Nanoengineered multimodal contrast agent for medical imaging guidance

Progress in Biomedical Optics and Imaging - Proceedings of SPIE

Volumn 5746, Issue I, 2005, Pages 31-39

  Perkins, Gregory J ^a   Zheng, Jinzi ^b   Brock, Kristy ^a   Allen, Christine ^c   Jaffray, David A ^a,b  

^a PRINCESS MARGARET HOSPITAL   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

Author keywords

Computed tomography (CT); Contrast agent; Image guidance; Image registration; Liposome; Magnetic resonance imaging (MRI); Multimodality imaging; Rabbit; Radiation therapy

Indexed keywords

BIOLOGICAL ORGANS; BLOOD; CELLS; COMPUTERIZED TOMOGRAPHY; IMAGE ANALYSIS; MAGNETIC RESONANCE IMAGING; NANOTECHNOLOGY; RADIOTHERAPY; TUMORS;

CONTRAST AGENT; IMAGE GUIDANCE; IMAGE REGISTRATION; LIPOSOME; MULTIMODALITY IMAGING; RABBIT;

BIOMEDICAL ENGINEERING;

EID: 23844490186     PISSN: 16057422     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1117/12.596038     Document Type: Conference Paper

References (30)

1. Jaffray DA, Siewerdsen JH, Wong JW, Martinez AA, "Flat-panel cone-beam computed tomography for image-guided radiation therapy", Int J Radiat Oncol Biol Phys, 53, 1337-1349, 2002.
2. Krause W, "Delivery of diagnostic agents in computed tomography", Adv Drug Deliv Rev, 37, 159-173, 1999.
3. McDonald MA, Watkin BS, Watkin KL, "Small Particulate Gadolinium Oxide and Gadolinium Oxide Albumin Microspheres as Multimodal Contrast and Therapeutic Agents", Invest Radiol, 38, 305-310, 2003.
4. Bloem JL, Wondergem J, "Gd-DTPA as a contrast agent in CT", Radiology, 171, 578-579, 1989.
5. Gierda DS, Bae KT, "Gadolinium as a CT contrast agent: assessment in a porcine model", Radiology, 210, 829-834, 1999.
6. Quinn AD, O'Hare NJ, Wallis FJ, et al., "Gd-DTPA: an alternative contrast medium for CT", J Comput Assist Tomogr, 18, 634-636, 1994.
7. Pena CS, Kaufman JA, Geller SC, et al., "Gadopentetate dimeglumine: a possible alternative contrast agent for CT angiography of the aorta", J Comput Assist Tomogr, 23, 23-24, 1999.
8. Liu J, Xiao Y, Allen C, "Polymer-drug compatibility: a guide to the development of delivery systems for the anticancer agent, ellipticine", J Pharm Sci, 93, 132-143, 2004.
9. Kao CY, Hoffman EA, Beck KC, Bellamkonda RV, Annapragada AV, "Long-residence-time nano-scale liposomal iohexol for X-ray-based blood pool imaging", Acad Radiol, 10, 475-483, 2003.
10. Leike JU, Sachse A, Rupp K, "Characterization of continuously extruded iopromide-carrying liposomes for computed tomography blood-pool imaging", Invest Radiol, 36, 303-308, 2001.
11. Leander P, Hoglund P, Borseth A, Kloster Y, Berg A, "A new liposomal liver-specific contrast agent for CT: first human phase-I clinical trial assessing efficacy and safety", Eur Radiol, 11, 698-704, 2001.
12. Schmiedl UP, Krause W, Leike J, Sachse A, "CT blood pool enhancement in primates with lopromide-carrying liposomes containing soy phosphatidyl glycerol", Acad Radiol, 6, 164-169, 1999.
13. Spinazzi A, Ceriati S, Pianezzola P, Lorusso V, Luzzani F, Fouillet X, Alvino S, Rummeny EJ, "Safety and pharmacokinetics of a new liposomal liver-specific contrast agent for CT: results of clinical testing in nonpatient volunteers", Invest Radiol, 35, 1-7, 2000.
14. Petersein J, Franke B, Fouillet X, Hamm B, "Evaluation of liposomal contrast agents for liver CT in healthy rabbits", Invest Radiol, 34, 401-409, 1999.
15. Leander P, Hoglund P, Kloster Y, Borseth A, "New liposomal liver-specific contrast agent for CT: first human phase I clinical trial assessing efficacy and safety", Acad Radiol, 5 Suppl 1, S6-8; discussion S28-30, 1998.
16. Krause W, Leike J, Schuhmann-Giampieri G, Sachse A, Schmiedl U, Strunk H, "Iopromide-carrying liposomes as a contrast agent for the liver", Acad Radiol, 3 Suppl 2, S235-237, 1996.
17. Dick A, Adam G, Tacke J, Prescher A, Southon TE, Gunther RW, "Computed tomography of experimental liver abscesses using a new liposomal contrast agent", Invest Radiol, 31, 194-203, 1996.
18. Revel D, Corot C, Carrillon Y, Dandis G, Eloy R, Amiel M, "Ioxaglate-carrying liposomes. Computed tomographic study as hepatosplenic contrast agent in rabbits", Invest Radiol, 25 Suppl 1, S95-97, 1990.
19. Musu C, Felder E, Lamy B, Schneider M, "A liposomal contrast agent. Preliminary communication", Invest Radiol, 23 Suppl 1, S126-129, 1988.
20. Zalutsky MR, Noska MA, Seltzer SE, "Characterization of liposomes containing iodine-125-labeled radiographic contrast agents", Invest Radiol, 22, 141-147, 1987.
21. Seltzer SE, Shulkin PM, Adams DF, Davis MA, Hoey GB, Hopkins RM, Bosworth ME, "Usefulness of liposomes carrying losefamate for CT opacification of liver and spleen", AJR Am J Roentgenol, 143, 575-579, 1984.
22. Jendrasiak GL, Frey GD, Heim RC, Jr., "Liposomes as carriers of iodolipid radiocontrast agents for CT scanning of the liver", Invest Radiol, 20, 995-1002, 1985.
23. Torchilin VP, "Polymeric contrast agents for medical imaging", Curr Pharm Biotechnol, 1, 183-215, 2000.
24. Schneider T, Sachse A, Roßling G, Brandi M., "Generation of contrast-carrying liposomes of defined size with a new continuous high pressure extrusion method." Int J Pharm, 117, 1-12, 1995.
25. Pauser S, Reszka R, Wagner S, Wolf KJ, Buhr HJ, Berger G, "Liposome-encapsulated superparamagnetic iron oxide particles as markers in an MRI-guided search for tumor-specific drug carriers", Anticancer Drug Des, 12, 125-135, 1997.
26. Raffy S, Teissie J, "Control of lipid membrane stability by cholesterol content", Biophys J, 76, 2072-2080, 1999.
27. Awasthi VD, Garcia D, Goins BA, Phillips WT, "Circulation and biodistribution profiles of long-circulating PEG-liposomes of various sizes in rabbits", Int J Pharm, 253, 121-132, 2003.
28. Takeuchi H, Kojima H, Yamamoto H, Kawashima Y, "Evaluation of circulation profiles of liposomes coated with hydrophilic polymers having different molecular weights in rats", J Control Release, 75, 83-91, 2001.
29. Allen TM, Hansen C, "Pharmacokinetics of stealth versus conventional liposomes: effect of dose", Biochim Biophys Acta, 1068, 133-141, 1991.
30. Allen C, Dos Santos N, Gallagher R, Chiu GN, Shu Y, Li WM, Johnstone SA, Janoff AS, Mayer LD, Webb MS, Bally MB, "Controlling the physical behavior and biological performance of liposome formulations through use of surface grafted poly(ethylene glycol)", Biosci Rep, 22, 225-250, 2002.