The effect of immunization on the response to P. gingivalis infection in mice is adjuvant-dependent

Journal of Clinical Periodontology

Volumn 32, Issue 9, 2005, Pages 933-937

  Houri Haddad, Yael ^a   Soskolne, W Aubrey ^a   Halabi, Amal ^a   Shapira, Lior ^a  

^a HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

Author keywords

Cytokines; Inflammation; Porphyromonas gingivalis; Porphyromonas gingivalis humoral response; Th1 Th2; Vaccine adjuvant

Indexed keywords

ALUMINUM POTASSIUM SULFATE; ALUMINUM SULFATE; FREUND ADJUVANT; IMMUNOLOGICAL ADJUVANT; INCOMPLETE FREUND'S ADJUVANT; INTERLEUKIN 1; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA (163 171); INTERLEUKIN-1BETA (163-171); LIPID; PEPTIDE FRAGMENT; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL; ARTICLE; BACTERIAL INFECTION; BAGG ALBINO MOUSE; COMPARATIVE STUDY; FEMALE; IMMUNIZATION; IMMUNOLOGY; LEUKOCYTE COUNT; MOUSE; PORPHYROMONAS GINGIVALIS;

ADJUVANTS, IMMUNOLOGIC; ALUM COMPOUNDS; ANIMALS; BACTEROIDACEAE INFECTIONS; FEMALE; FREUND'S ADJUVANT; IMMUNIZATION; INTERLEUKIN-1; INTERLEUKIN-18; INTERLEUKIN-1BETA; LEUKOCYTE COUNT; LIPIDS; MICE; MICE, INBRED BALB C; PEPTIDE FRAGMENTS; PORPHYROMONAS GINGIVALIS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 23844477030     PISSN: 03036979     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-051X.2005.00768.x     Document Type: Article

References (23)

1. Baker, P. J., Evans, T. & Roopenian, D. C. (1994) Oral infection with Porphyromonas gingivalis and induced alveolar bone loss in immunocompetent and severe combined immunodeficient mice. Archives of Oral Biology 39, 1035-1040.
2. Brewer, J. M., Conacher, M., Hunter, C. A., Mohrs, M., Brombacher, F. & Alexander, J. (1999) Aluminium hydroxide adjuvant initiates strong antigen-specific Th2 responses in the absence of IL-4- or IL-13-mediated signaling. The Journal of Immunology 163, 6448-6454.
3. Carter, L. L. & Dutton, R. W. (1996) Type 1 and type 2: a fundamental dichotomy for all T cell subsets. Current Opinions on Immunology 8, 336.
4. Chen, P. B., Daveru, L. B., Schifferl, R. & Zambon, J. J. (1990) Protective immunization against experimental Bacteroides (Porphyromonas) gingivalis infection. Infection and Immunity 58, 3394-3400.
5. Ebersole, J. L., Steffen, M. J., Holt, S. C. & Kornman, K. S. (1991) Effect of immunization with Porphyromonas gingivalis and Provetella intermedia on disease progression in ligature induced periodontitis in the nonhuman primate, Macaca fascicularis. Infection and Immunity 59, 3351-3359.
6. Frolove, I., Houri-Haddad, Y., Soskolne, W. A. & Shapira, L. (1998) In vivo exposure to Porphyromonas gingivalis up regulates nitric oxide but suppresses tumor necrosis factor alpha production by cultured macrophages. Immunology 93, 323-328.
7. Gemmell, E., Winning, T. A., Bird, P. S. & Seymour, G. J. (1998) Cytokine profiles of lesional and spleenic T cells in Porphyromonas gingivalis infection in a murine model. J Periodontology 69, 1131-1138.
8. Gonzalez, D., Tzianabos, A. O., Genco, C. A. & Gibson, F. C. (2003) Immunization with Porphyromonas gingivalis capsular polysaccharide prevents P. gingivalis-elicited oral bone loss in a murine model. Infection and Immunity 71, 2283-2287.
9. Genco, C. A., Odusanya, B. M., Potempa, J., Mikolajczyk-Pawlinska, J. & Travis, J. (1998) A. peptide domain on gingipain R which confers immunity against Porphromonas gingivalis infection in mice. Infection and Immunity 66, 4108-4114.
10. Houri-Haddad, Y., Soskolne, W. A., Halabi, A., Barak, V. & Shapira, L. (2000) Repeat bacterial challenge in a subcutaneous chamber model results in augmented tumor necrosis factor-α and interferon-γ response, and suppression of interleukin-10. Immunology 99, 215-220.
11. Houri-Haddad, Y., Soskolne, W. A. & Shapira, L. (2001) Immunization to Porphyromonas gingivalis enhances the local pro-inflammatory response to subcutaneous bacterial challenge. Journal of Clinical Periodontology 28, 476-482.
12. Kesavalu, L., Ebersole, J. L., Machen, R. L. & Holt, S. C. (1992) Porphyromonas gingivalis virulence in mice: Induction of immunity to bacterial components. Infection and Immunity 60, 1455-1464.
13. Kojima, T., Yano, K. & Ishikawa, I. (1997) Relationship between serum antibody levels and subgingival colonization of Porphyromonas gingivalis in patients with various types of periodontitis. Journal of Periodontology 68, 618-625.
14. Moritz, A. J., Cappelli, D., Lantz, M. S., Holt, S. C. & Ebersole, J. L. (1998) Immunization with Porphyromonas gingivalis cysteine protease: effect on experimental gingivitis and ligature induced periodontitis in Macaca fascicularis. Journal of Periodontology 69, 686-697.
15. Mooney, J. & Kinane, D. F. (1997) Levels of specific immunoglobulin G to Porphyromonas gingivalis in gingival crevicular fluid are related to site disease status. Oral Microbiology and Immunology 12, 112-116.
16. Mosmann, T. R. & Coffman, R. L. (1989) Th1 and Th2 cells: different patterns of lymphokine secretion lead to different functional properties. Annual Review on Immunology 7, 145-173.
17. Okuda, K., Kato, T. & Naito, Y. (1988) Protective efficacy of active and passive immunization against experimental infections with Bacteroides gingivalis in ligated hamsters. Journal of Dental Research 67, 807-811.
18. Okuda, K., Saito, T., Hirai, K., Harano, K. & Kato, T. (1994) Role of antibodies in periodontopathic bacterial infection. In: Genco, R. J., Hamada, S., Lehner, T., Mcghee, J. & Mergenhagen, S. (eds). Molecular Pathogenesis of Periodontal Disease, pp. 257-265. Washington, DC: ASM Press.
19. Page, R. C. (2000) Vaccination and periodontitis: myth or reality. Journal of International Academic Periodontology 2, 31-43.
20. Persson, G. R., Engel, D. & Whitney, C. (1994) Immunization against Porphyromonas gingivalis inhibits progression of periodontitis in nonhuman primates. Infection and Immunity 62, 1026-1031.
21. Romagnani, S. (1996) Short analytical review of Th1 and Th2 in human diseases. Clinical Immunology and Immunopathology 80, 225-235.
22. Stashenko, P., Jandinski, J. J., Fujiyioshi, P., Rynar, J. & Socranski, S. S. (1991) Tissue levels of bone resorptive cytokines in periodontal disease. Journal of Periodontology 62, 504-509.
23. Tew, J. G., Marshall, D. R., Moor, W. E. C., Best, A. M., Palcanis, U. G. & Ranney, R. R. (1985) Serum antibody with predominant organisms in the subgingival flora of young adults with generalized severe periodontitis. Infection and Immunity 48, 303-311.