Plasma levels of polyunsaturated fatty acids in children with atopic dermatitis and in atopic and non-atopic controls

Wiener Klinische Wochenschrift

Volumn 117, Issue 13-14, 2005, Pages 485-491

  Focke, Margarete ^a   Sesztak Greinecker, Gabriele ^a   Brannath, Werner ^b   Götz, Manfred ^a   Jarisch, Reinhart ^a   Hemmer, Wolfgang ^a,c  

^a FAZ Floridsdorf Allergy Centre   (Austria)

^b MEDICAL UNIVERSITY OF VIENNA   (Austria)

^c FAZ Floridsdorf Allergy Center   (Austria)

Author keywords

Atopic dermatitis; Delta 6 desaturase; Essential fatty acids; Gammalinolenic acid; Polyunsaturated fatty acids

Indexed keywords

ARACHIDONIC ACID; GAMMA LINOLENIC ACID; IMMUNOGLOBULIN E; LINOLEIC ACID; POLYUNSATURATED FATTY ACID;

ALLERGIC RHINITIS; ARTICLE; ASTHMA; ATOPIC DERMATITIS; BLOOD LEVEL; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; ECZEMA; FATTY ACID METABOLISM; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; LIPID ANALYSIS; MALE; STATISTICAL ANALYSIS; SUPPLEMENTATION;

ASTHMA; BIOLOGICAL MARKERS; CHILD; DERMATITIS, ATOPIC; FATTY ACIDS, UNSATURATED; FEMALE; HUMANS; IMMUNOGLOBULIN E; MALE; PREVALENCE; PROGNOSIS; RHINITIS, ALLERGIC, PERENNIAL; RISK ASSESSMENT; RISK FACTORS;

EID: 23844469828     PISSN: 00435325     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00508-005-0394-z     Document Type: Article

References (29)

1. Hansen AE (1937) Serum lipids in eczema and other pathological conditions. Am J Dis Child 53: 933-946
2. Manku MS, Horrobin DF, Morse NL, Wright S, Burton JL (1984) Essential fatty acids in the plasma phospholipids of patients with atopic eczema. Br J Dermatol 110: 643-648
3. Oliwiecki S, Burton JL, Elles K, Horrobin DF (1990) Levels of essential and other fatty acids in plasma and red cell phospholipids from normal controls and patients with atopic eczema. Acta Derm Venerol 71: 224-228
4. Melnik BC, Plewig G (1989) Is the origin of atopy linked to deficient conversion of omega 6 fatty acids to prostaglandin E1. J Am Acad Dermatol 21: 557-563
5. Horrobin DF (1993) Fatty acid metabolism in health and disease: the role of delta 6 desaturase. Am J Clin Nutr 57 [Suppl 5]: 732-737
6. Wright S, Burton JL (1982) Oral evening-primrose-seed oil improves atopic dermatitis. Lancet 2(8308): 1120-1122
7. Manku MS, Horrobin DF, Morse N, Kyte V, Jenkins K, Wright S, et al (1982) Reduced levels of prostaglandin precursors in the blood of atopic patients: defective delta-6-desaturase function as a biochemical basis for atopy. Prostaglandins Leukot Med 9: 615-628
8. Ziboh VA (1989) Implications of dietary oils and polyunsaturated fatty acids in the management of cutaneous disorders. Arch Dermatol 125: 241-245
9. Horrobin DF, Manku MS, Huang YS (1984) Effects of essential fatty acids on prostaglandin biosynthesis. Biomed Biochim Acta 43: S114-120
10. Schalin-Karrila M, Mattila L, Jansen CT, Uotila P (1987) Evening primrose oil in the treatment of atopic eczema: effect on clinical status, plasma phospholipid fatty acids and circulating blood prostaglandins. Br J Dermatol 117: 11-19
11. Bordoni A, Biagi PL, Masi M, Ricci G, Fanelli C, Patrizi A, et al (1988) Evening primrose oil (Efamol) in the treatment of children with atopic eczema. Drugs Exp Clin Res 14: 291-297
12. Bamford JTM, Gibson RW, Renier CMR (1985) Atopic eczema unresponsive to evening primrose oil (linoleic and gamma-linolenic acids). J Am Acad Dermatol 13: 959-965
13. Berth-Jones J, Graham-Brown RAC (1993) Placebo-controlled trial of essential fatty acid supplementation in atopic dermatitis. Lancet 341: 1557-1560
14. Henz BM, Jablonska S, van de Kerkhof PC, Stingl G, Blaszczyk M, Vandervalk PG, et al (1999) Double-blind, multicentre analysis of the efficacy of borage oil in patients with atopic eczema. Br J Dermatol 140: 685-688
15. Takwale A, Tan E, Agarwal S, Barclay G, Ahmed I, Hotchkiss K, et al (2003) Efficacy and tolerability of borage oil in adults and children with atopic eczema: randomised, double blind, placebo controlled, parallel group trial. BMJ 327: 1385
16. van Gool CJ, Zeegers MP, Thijs C (2004) Oral essential fatty acid supplementation in atopic dermatitis - a meta-analysis of placebo-controlled trials. Br J Dermatol 150: 728-740
17. Hanifin JM, Rajka G (1980) Diagnostic features of atopic dermatitis. Acta Derm Venereol 92: S44-47
18. Kjellman NIM, Johansson SGO, Roth A (1976) Serum IgE levels in healthy children quantified by a sandwich technique (PRIST). Clin Allergy 6: 51-59
19. Bligh E, Dyer N (1959) A rapid method of total lipid extraction and purification. Can J Biochem Physiol 37: 9-11
20. Jüngling E, Kammermeier H (1988) A one-vial method for routine extraction and quantification of free fatty acids in blood and tissue by HPLC. Anal Biochem 171: 150-157
21. Strannegard IL, Svennerholm L, Strannegard O (1987) Essential fatty acids in serum lecithin of children with atopic dermatitis and in umbilical cord serum of infants with high or low IgE levels. Int Arch Allergy Appl Immunol 82: 422-423
22. Rocklin RE, Thistle L, Gallant L, Manku MS, Horrobin D (1986) Altered arachidonic acid content in polymorphonuclear and mononuclear cells from patients with allergic rhinitis and/or asthma. Lipids 21: 17-20
23. Galli E, Picardo M, Chini L, Passi S, Moschese V, Terminali O, et al (1994) Analysis of polyunsaturated fatty acids in newborn sera: a screening tool for atopic disease? Br J Dermatol 130: 752-756
24. Leichsenring M, Kochsiek U, Paul K (1995) (n-6)-Fatty acids in plasma lipids of children with atopic bronchial asthma. Pediatr Allergy Immunol 6: 209-212
25. Businco L, Ioppi M, Morse NL, Nisini R, Wright S (1993) Breast milk from mothers of children with newly developed atopic eczema has low levels of long chain polyunsaturated fatty acids. J Allergy Clin Immunol 91: 1134-1139
26. Thijs C, Houwelingen A, Poorterman I, Mordant A, van den Brandt P (2000) Essential fatty acids in breast milk of atopic mothers: comparison with non-atopic mothers, and effect of borage oil supplementation. Eur J Clin Nutr 54: 234-238
27. Kankaanpää P, Nurmela K, Erkkilä A, Kalliomäki M, Holmberg-Marttila D, Salminen S, et al (2001) Polyunsaturated fatty acids in maternal diet, breast milk, and serum lipid fatty acids of infants in relation to atopy. Allergy 56: 633-638
28. Yu G, Björkstén B (1998) Polyunsaturated fatty acids in school children in relation to allergy and serum IgE levels. Pediatr Allergy Immunol 9: 133-138
29. Duchen K, Yu G, Björkstén B (1998) Atopic sensitization during the first year of life in relation to chain polyunsaturated fatty acid levels in human milk. Pediatr Res 44: 478-484