Development of DNA polymerase IIIC inhibitors for the treatment of Gram-positive bacterial infections

Expert Opinion on Therapeutic Patents

Volumn 15, Issue 8, 2005, Pages 947-953

  Ali, Amjad ^a   Taylor, Gayle E ^b  

^a MERCK RESEARCH LABORATORIES   (United States)

^b NONE

Author keywords

6 anilinouracil; Antibacterial; DNA polymerase IIIC; Gram positive bacteria

Indexed keywords

ANTIBIOTIC AGENT; CIPROFLOXACIN; DNA DIRECTED DNA POLYMERASE GAMMA; DNA DIRECTED DNA POLYMERASE GAMMA INHIBITOR; EXONUCLEASE; METICILLIN; NUCLEOTIDYLTRANSFERASE INHIBITOR; QUINOLONE DERIVATIVE; UNCLASSIFIED DRUG; VANCOMYCIN;

ANTIBACTERIAL ACTIVITY; BACTERIAL INFECTION; DNA REPLICATION; DNA SYNTHESIS INHIBITION; DRUG EFFICACY; DRUG STRUCTURE; ENZYME INHIBITION; GENE SEQUENCE; GRAM POSITIVE BACTERIUM; HYDROGEN BOND; IN VITRO STUDY; IN VIVO STUDY; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PATENT; REVIEW; SEQUENCE HOMOLOGY; STAPHYLOCOCCUS AUREUS;

EID: 23844469268     PISSN: 13543776     EISSN: None     Source Type: Journal    
DOI: 10.1517/13543776.15.8.947     Document Type: Review

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