6-anilinouracil-based inhibitors of bacillus subtilis DNA polymerase III: Antipolymerase and antimicrobial structure-activity relationships based on substitution at uracil N3

Journal of Medicinal Chemistry

Volumn 42, Issue 11, 1999, Pages 2035-2040

  Tarantino Jr , Paul M ^b   Zhi, Chengxin ^a,b   Gambino, Joseph J ^b   Wright, George E ^b   Brown, Neal C ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b GLSYNTHESIS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

6 (3 ETHYL 4 METHYLANILINO)URACIL; 6 (3,4 TRIMETHYLENEANILINO)URACIL; 6 ANILINOURACIL; DNA DIRECTED DNA POLYMERASE GAMMA; UNCLASSIFIED DRUG; URACIL DERIVATIVE;

ANTIMICROBIAL ACTIVITY; ARTICLE; BACILLUS SUBTILIS; BACTERIAL GROWTH; BACTERIUM CULTURE; DRUG EFFECT; DRUG MECHANISM; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; GRAM POSITIVE BACTERIUM; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; STRUCTURE ACTIVITY RELATION;

ANTI-BACTERIAL AGENTS; BACILLUS SUBTILIS; DNA POLYMERASE III; ENZYME INHIBITORS; MICROBIAL SENSITIVITY TESTS; STRUCTURE-ACTIVITY RELATIONSHIP; URACIL;

EID: 0344171944     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm980693i     Document Type: Article

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