Design and synthesis of novel antibacterial agents with inhibitory activity against DNA polymerase III

Bioorganic and Medicinal Chemistry Letters

Volumn 11, Issue 16, 2001, Pages 2185-2188

  Ali, Amjad ^a   Aster, Susan D ^a   Graham, Donald W ^a   Patel, Gool F ^a   Taylor, Gayle E ^a   Tolman, Richard L ^a   Painter, Ronald E ^a   Silver, Lynn L ^a   Young, Katherine ^a   Ellsworth, Kenneth ^a   Geissler, Wayne ^a   Harris, Georgianna S ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINO 6 (ANILINO)PYRIMIDINE DERIVATIVE; ANTIINFECTIVE AGENT; DNA DIRECTED DNA POLYMERASE GAMMA; ENZYME INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DNA SYNTHESIS; DRUG DESIGN; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME INHIBITION; IC 50; NONHUMAN; REACTION ANALYSIS; STAPHYLOCOCCUS AUREUS; STRAIN DIFFERENCE;

ANILINE COMPOUNDS; ANTI-BACTERIAL AGENTS; DNA POLYMERASE III; DRUG DESIGN; ENZYME INHIBITORS; MICROBIAL SENSITIVITY TESTS; PYRIMIDINES; STAPHYLOCOCCUS AUREUS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 17944369343     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(01)00407-3     Document Type: Article

References (19)