A Cre gene directed by a human TSPY promoter is specific for germ cells and neurons

Genesis (United States)

Volumn 42, Issue 4, 2005, Pages 263-275

  Kido, Tatsuo ^a   Lau, Yun Fai Chris ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Cre recombinase; Germ cell; Gonadoblastoma; Neurons; Transgenic mice; TSPY promoter

Indexed keywords

CRE RECOMBINASE; GREEN FLUORESCENT PROTEIN; RNA;

ADOLESCENT; ADULT; ADULTHOOD; AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN; CARCINOGENESIS; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; EMBRYO; FEMALE; GAMETOGENESIS; GENE; GENE EXPRESSION; GERM CELL; GONADOBLASTOMA; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; MOUSE; NERVE CELL; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; OVARY; PERINATAL PERIOD; PERIPHERAL NERVOUS SYSTEM; PRIORITY JOURNAL; PROMOTER REGION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPINAL GANGLION; TESTIS; TISSUE SPECIFICITY; TRANSGENIC MOUSE; TRIGEMINAL NERVE; TRIGEMINUS GANGLION; TSPY GENE; Y CHROMOSOME;

MUS MUSCULUS;

EID: 23844468154     PISSN: 1526954X     EISSN: None     Source Type: Journal    
DOI: 10.1002/gene.20147     Document Type: Article

References (43)

1. Arnemann J, Epplen JT, Cooke HJ, Sauermann U, Engel W, Schmidtke J. 1987. A human Y-chromosomal DNA sequence expressed in testicular tissue. Nucleic Acids Res 15:8713-8724.
2. Arnold AP, Burgoyne PS. 2004. Are XX and XY brain cells intrinsically different? Trends Endocrinol Metab 15:6-11.
3. Canela N, Rodriguez-Vilarrupla A, Estanyol JM, Diaz C, Pujol MJ, Agell N, Bachs O. 2003. The SET protein regulates G2/M transition by modulating cyclin B-cyclin-dependent kinase 1 activity. J Biol Chem 278:1158-1164.
4. Chai Z, Sarcevic B, Mawson A, Toh BH. 2001. SET-related cell division autoantigen-1 (CDA1) arrests cell growth. J Biol Chem 276:33665-33674.
5. De Smet C, Lurquin C, Lethe B, Martelange V, Boon T. 1999. DNA methylation is the primary silencing mechanism for a set of germ line- and tumor-specific genes with a CpG-rich promoter. Mo l Cell Biol 19:7327-7335.
6. De Vries GJ. 2004. Minireview: Sex differences in adult and developing brains: compensation, compensation, compensation. Endocrinology 145:1063-1068.
7. Debus E, Weber K, Osborn M. 1983. Monoclonal antibodies specific for glial fibrillary acidic (GFA) protein and for each of the neurofilament triplet polypeptides. Differentiation 25:193-203.
8. Friedrich H, Walter L, Gunther E. 1998. Analysis of the 5′-flanking regions of the MHC-linked Hsp70-2 and Hsp70-3 genes of the rat. Biochim Biophys Acta 1395:57-61.
9. Hisano M, Ohta H, Nishimune Y, Nozaki M. 2003. Methylation of CpG dinucleotides in the open reading frame of a testicular germ cell-specific intronless gene, Tact1/Act17b, represses its expression in somatic cells. Nucleic Acids Res 31:4797-4804.
10. Honecker F, Stoop H, De Krijger RR, Chris Lau YF, Bokemeyer C, Looijenga LH, 2004. Pathobiological implications of the expression of markers of testicular carcinoma in situ by fetal germ cells. J Pathol 203:849-857.
11. Iannello RC, Gould JA, Young JC, Giudice A, Medcalf R, Kola I. 2000. Methylation-dependent silencing of the testis-specific Pdha-2 basal promoter occurs through selective targeting of an activating transcription factor/cAMP-responsive element-binding site. J Biol Chem 275:19603-19608.
12. Ishimi Y, Kikuchi A. 1991. Identification and molecular cloning of yeast homolog of nucleosome assembly protein I which facilitates nucleosome assembly in vitro. J Biol Chem 266:7025-7029.
13. Jorgensen N, Muller J, Jaubert F, Clausen OP, Skakkebaek NE. 1997. Heterogeneity of gonadoblastoma germ cells: similarities with immature germ cells, spermatogonia and testicular carcinoma in situ cells. Histopathology 30:177-186.
14. Kellogg DR, Kikuchi A, Fujii-Nakata T, Turck CW, Murray AW. 1995. Members of the NAP/SET family of proteins interact specifically with B-type cyclins. J Cell Biol 130:661-673.
15. Lau W. 1999. Gonadoblastoma, testicular and prostate cancers, and the TSPY gene. Am J Hum Genet 64:921-927.
16. Lau YF, Zhang J. 2000. Expression analysis of thirty one Y chromosome genes in human prostate cancer. Mol Carcinog 27:308-321.
17. Lau Y, Chou P, Iezzoni J, Alonzo J, Komuves L. 2000. Expression of a candidate gene for the gonadoblastoma locus in gonadoblastoma and testicular seminoma. Cytogenet Cell Genet 91:160-164.
18. Lau YF, Lau HW, Komuves LG. 2003. Expression pattern of a gonadoblastoma candidate gene suggests a role of the Y chromosome in prostate cancer. Cytogenet Genome Res 101:250-260.
19. MacLusky NJ, Naftolin F 1981. Sexual differentiation of the central nervous system. Science 211:1294-1302.
20. Mazeyrat S, Mitchell MJ. 1998. Rodent Y chromosome TSPY gene is functional in rat and non-functional in mouse. Hum Mol Genet 7:557-562.
21. Mullen RJ, Buck CR, Smith AM. 1992. NeuN, a neuronal specific nuclear protein in vertebrates. Development 116:201-211.
22. Niwa H, Yamamura K, Miyazaki J. 1991. Efficient selection for high-expression transfectants with a novel eukaryotic vector. Gene 108:193-199.
23. Novak A, Guo C, Yang W, Nagy A, Lobe CG. 2000. Z/EG, a double reporter mouse line that expresses enhanced green fluorescent protein upon Cre-mediated excision. genesis 28:147-155.
24. Oh HJ, Li Y, Lau YF. 2005. Sry associates with the heterochromatin protein 1 complex by interacting with a KRAB domain protein. Biol Reprod 72:407-415.
25. Ozbun LL, You L, Kiang S, Angdisen J, Martinez A, Jakowlew SB. 2001. Identification of differentially expressed nucleolar TGF-beta1 target (DENTT) in human lung cancer cells that is a new member of the TSPY/SET/NAP-1 superfamily. Genomics 73:179-193.
26. Page DC. 1987. Hypothesis: a Y-chromosomal gene causes gonadoblastoma in dysgenetic gonads. Development 101(Suppl):151-155
27. Puffenberger EG, Hu-Lince D, Parod JM, Craig DW, Dobrin SE, Conway AR, Donarum EA, Strauss KA, Dunckley T, Cardenas JF, Melmed KR, Wright CA, Liang W, Stafford P, Flynn CR, Morton DH, Stephan DA. 2004. Mapping of sudden infant death with dysgenesis of the testes syndrome (SIDDT) by a SNP genome scan and identification of TSPYL loss of function. Proc Natl Acad Sci U S A 101:11689-11694.
28. Rajpert-De-Meyts E, Bartkova J, Samson M, Hoei-Hansen CE, Frydelund-Larsen L, Bartek J, Skakkebaek NE. 2003. The emerging phenotype of the testicular carcinoma in situ germ cell. APMIS 111:267-278; discussion 278-279.
29. Rupp RA, Snider L, Weintraub H. 1994. Xenopus embryos regulate the nuclear localization of XMyoD. Genes Dev 8:1311-1323.
30. Salo P, Kaariainen H, Petrovic V, Peltomaki P, Page DC, de la Chapelle A. 1995. Molecular mapping of the putative gonadoblastoma locus on the Y chromosome. Genes Chromsomes Cancer 14:210-214.
31. Schnieders F, Dork T, Arnemann J, Vogel T, Werner M, Schmidtke J. 1996. Testis-specific protein, Y-encoded (TSPY) expression in testicular tissues. Hum Mol Genet 5:1801-1807.
32. Schubert S, Skawran B, Dechend F, Nayernia K, Meinhardt A, Nanda I, Schmid M, Engel W, Schmidtke J. 2003. Generation and characterization of a transgenic mouse with a functional human TSPY. Biol Reprod 69:968-975.
33. Seo SB, McNamara P, Heo S, Turner A, Lane WS, Chakravarti D. 2001. Regulation of histone acetylation and transcription by INHAT, a human cellular complex containing the set oncoprotein. Cell 104:119-130.
34. Skaletsky H, Kuroda-Kawaguchi T, Minx PJ, Cordum HS, Hillier L, Brown LG, Repping S, Pyntikova T, Ali J, Bieri T, Chinwalla A, Delehaunty A, Delehaunty K, Du H, Fewell G, Fulton L, Fulton R, Graves T, Hou SF, Latrielle P, Leonard S, Mardis E, Maupin R, McPherson J, Miner T, Nash W, Nguyen C, Ozersky P, Pepin K, Rock S, Rohlfing T, Scott K, Schultz B, Strong C, Tin-Wollam A, Yang SP, Waterston RH, Wilson RK, Rozen S, Page DC. 2003. The male-specific region of the human Y chromosome is a mosaic of discrete sequence classes. Nature 423:825-837.
35. Steger K. 1999. Transcriptional and translational regulation of gene expression in haploid spermatids. Anat Embryol (Berl) 199:471-487.
36. Tascou S, Nayernia K, Samani A, Schmidtke J, Vogel T, Engel W, Burfeind P. 2000. Immortalization of murine male germ cells at a discrete stage of differentiation by a novel directed promoter-based selection strategy. Biol Reprod 63:1555-1561.
37. Tsuchiya K, Reijo R, Page DC, Disteche CM. 1995. Gonadoblastoma: molecular definition of the susceptibility region on the Y chromosome. Am J Hum Genet 57:1400-1407.
38. Turner DL, Weintraub H. 1994. Expression of achaete-scute homolog 3 in Xenopus embryos converts ectodermal cells to a neural fate. Genes Dev 8:1434-1447.
39. Turner JM, Mahadevaiah SK, Fernandez-Capetillo O, Nussenzweig A, Xu X, Deng CX, Burgoyne PS. 2005. Silencing of unsynapsed meiotic chromosomes in the mouse. Nat Genet 37:41-47.
40. Vogel T, Dittrich O, Mehraein Y, Dechend F, Schnieders F, Schmidtke J. 1998. Murine and human TSPYL genes: novel members of the TSPY-SET-NAP1L1 family. Cytogenet Cell Genet 81:265-270.
41. von Lindern M, van Baal S, Wiegant J, Raap A, Hagemeijer A, Grosveld G. 1992. Can, a putative oncogene associated with myeloid leukemogenesis, may be activated by fusion of its 3′ half to different genes: characterization of the set gene. Mol Cell Biol 12:3346-3355.
42. Wang MM, Reed RR. 1993. Molecular cloning of the olfactory neuronal transcription factor Olf-1 by genetic selection in yeast. Nature 364:121-126.
43. Zhang JS, Yang-Feng TL, Muller U, Mohandas TK, de Jong PJ, Lau YF. 1992. Molecular isolation and characterization of an expressed gene from the human Y chromosome. Hum Mol Genet 1:717-726.