Mutations increasing exposure of a receptor binding site epitope in the soluble and oligomeric forms of the caprine arthritis-encephalitis lentivirus envelope glycoprotein

Virology

Volumn 339, Issue 2, 2005, Pages 261-272

  Hötzel, Isidro ^a,b   Cheevers, William P ^a  

^a WASHINGTON STATE UNIVERSITY   (United States)

^b GENENTECH INC   (United States)

Author keywords

CAEV; Conformation; Entropy; Glycoprotein; HIV 1; Lentivirus; Neutralization; Neutralization resistance; Receptor; Rotamer

Indexed keywords

ALANINE; DETERGENT; EPITOPE; GLYCOPROTEIN GP 120; GLYCOPROTEIN GP 135; ISOLEUCINE; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY F7 299; OLIGOMER; UNCLASSIFIED DRUG; VIRUS ENVELOPE PROTEIN; VIRUS GLYCOPROTEIN; VIRUS RECEPTOR;

ANTIGEN BINDING; ARTICLE; BAY REGION BINDING SITE; BINDING AFFINITY; CAPRINE ARTHRITIS ENCEPHALITIS VIRUS; CELL ADHESION; CONTROLLED STUDY; GENE DELETION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; IMMUNOGLOBULIN VARIABLE REGION; MOLECULAR RECOGNITION; MUTAGENESIS; MUTANT; MUTATION; NONHUMAN; NUCLEOTIDE SEQUENCE; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN LOCALIZATION; PROTEIN STABILITY; RECEPTOR BINDING; VIRUS ENVELOPE; VIRUS NEUTRALIZATION; WILD TYPE;

ANIMALS; ARTHRITIS-ENCEPHALITIS VIRUS, CAPRINE; CELL LINE; GENE PRODUCTS, ENV; GLYCOPROTEINS; MEMBRANE PROTEINS; MUTATION; VIRAL PROTEINS;

CAPRA; CAPRA HIRCUS; CAPRINE ARTHRITIS-ENCEPHALITIS VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; LENTIVIRUS; MAEDI-VISNA VIRUS; OVIS;

EID: 23844451791     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.virol.2005.05.028     Document Type: Article

References (34)

1. J. Cao, N. Sullivan, E. Desjardin, C. Parolin, J. Robinson, R. Wyatt, and J. Sodroski Replication and neutralization of human immunodeficiency virus type 1 lacking the V1 and V2 variable loops of the gp120 envelope glycoprotein J. Virol. 71 1997 9808 9812
2. W.P. Cheevers, and T.C. McGuire The lentiviruses: maedi/visna, caprine arthritis-encephalitis, and equine infectious anemia Adv. Virus Res. 34 1988 189 215
3. W.P. Cheevers, D.P. Knowles, and L.K. Norton Neutralization-resistant antigenic variants of caprine arthritis-encephalitis lentivirus associated with progressive arthritis J. Infect. Dis. 164 1991 679 685
4. W.P. Cheevers, T.C. McGuire, L.K. Norton, R. Cordery-Cotter, and D.P. Knowles Failure of neutralizing antibody to regulate CAE lentivirus expression in vivo Virology 196 1993 835 839
5. B. Chen, E.M. Vogan, H. Gong, J.J. Skehel, D.C. Wiley, and S.C. Harrison Structure of an unliganded simian immunodeficiency virus gp120 core Nature 433 2005 834 841
6. T.B. Crawford, D.S. Adams, W.P. Cheevers, and L.C. Cork Chronic arthritis in goats caused by a retrovirus Science 207 1980 997 999
7. I. Hötzel Conservation of the human immunodeficiency virus type 1 gp120 V1/V2 stem/loop structure in the equine infectious anemia virus (EIAV) gp90 AIDS Res. Hum. Retroviruses 19 2003 923 924
8. I. Hötzel, and W.P. Cheevers Sequence similarity between the envelope surface unit (SU) glycoproteins of primate and small ruminant lentiviruses Virus Res. 69 2000 47 54
9. I. Hötzel, and W.P. Cheevers Conservation of human immunodeficiency virus type 1 gp120 inner-domain sequences in lentivirus and type A and B retrovirus envelope surface glycoproteins J. Virol. 75 2001 2014 2018
10. I. Hötzel, and W.P. Cheevers Differential receptor usage of small ruminant lentiviruses in ovine and caprine cells: host range but not cytopathic phenotype is determined by receptor usage Virology 301 2002 21 31
11. I. Hötzel, and W.P. Cheevers Caprine arthritis-encephalitis virus envelope surface glycoprotein regions interacting with the transmembrane glycoprotein: structural and functional parallels with the human immunodeficiency virus type 1 gp120 J. Virol. 77 2003 11578 11587
12. G.A. Hullinger, D.P. Knowles, T.C. McGuire, and W.P. Cheevers Caprine arthritis-encephalitis lentivirus SU is the ligand for infection of caprine synovial membrane cells Virology 192 1993 328 331
13. R.K. Kemp, D.P. Knowles, L.L. Perry, T.C. McGuire, T.E. Besser, and W.P. Cheevers Crossreactive neutralizing antibodies induced by immunization with caprine arthritis-encephalitis virus surface glycoprotein Vaccine 18 2000 1282 1287
14. P. Klevjer-Anderson, and W.P. Cheevers Characterization of the infection of caprine synovial membrane cells by the retrovirus caprine arthritis-encephalitis virus Virology 110 1981 113 119
15. D.P. Knowles, W.P. Cheevers, T.C. McGuire, A.L. Brassfield, W.G. Harwood, and T.A. Stem Structure and genetic variability of envelope glycoproteins of two antigenic variants of caprine arthritis-encephalitis lentivirus J. Virol. 65 1991 5744 5750
16. P.D. Kwong, R. Wyatt, J. Robinson, R.W. Sweet, J. Sodroski, and W.A. Hendrickson Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody Nature 393 1998 648 659
17. P.D. Kwong, R. Wyatt, Q.J. Sattentau, J. Sodroski, and W.A. Hendrickson Oligomeric modeling and electrostatic analysis of the gp120 envelope glycoprotein of human immunodeficiency virus J. Virol. 74 2000 1961 1972
18. P.D. Kwong, M.L. Doyle, D.J. Casper, C. Cicala, S.A. Leavitt, S. Majeed, T.D. Steenbeke, M. Venturi, I. Chalken, M. Fung, H. Katinger, P.W.I.H. Parren, J. Robinson, D. Van Ryk, L. Wang, D.R. Burton, E. Freire, R. Wyatt, J. Sodroski, W.A. Hendrickson, and J. Arthos HIV-1 evades antibody-mediated neutralization through conformational masking of receptor-binding sites Nature 420 2002 678 682
19. J.W. Lyall, N. Solanky, and L.S. Tiley Restricted species tropism of maedi-visna virus strain EV-1 is not due to limited receptor distribution J. Gen. Virol. 81 2000 2919 2927
20. D.G. Myszka, R.W. Sweet, P. Hensley, M. Brigham-Burke, P.D. Kwong, W.A. Hendrickson, R. Wyatt, J. Sodroski, and M.L. Doyle Energetics of the HIV gp120-CD4 binding reaction Proc. Natl. Acad. Sci. U.S.A. 97 2000 9026 9031
21. O. Narayan, D. Sheffer, D.E. Griffin, J. Clements, and J. Hess Lack of neutralizing antibodies to caprine arthritis-encephalitis lentivirus in persistently infected goats can be overcome by immunization with inactivated Mycobacterium tuberculosis J. Virol. 49 1984 349 355
22. O. Narayan, M. Zink, M. Gorrel, S. Crane, D. Huso, P. Jolly, M. Saltarelli, R. Adams, and J. Clements The lentiviruses of sheep and goats J.A. Levy The Retroviridae 1993 Plenum Press New York 229 256
23. F. Özyörük, W.P. Cheevers, G.A. Hullinger, T.C. McGuire, M. Hutton, and D.P. Knowles Monoclonal antibodies to conformational epitopes of the surface glycoprotein of caprine arthritis-encephalitis virus: potential application to competitive-inhibition enzyme-linked immunosorbent assay for detecting antibodies in goat sera Clin. Diagn. Lab. Immunol. 8 2001 44 51
24. C.N. Pace, F. Vajdos, L. Fee, G. Grimsley, and T. Gray How to measure and predict the molar absorption coefficient of a protein Protein Sci. 4 1995 2411 2423
25. P. Poignard, P.J. Klasse, and Q.J. Sattentau Antibody neutralization of HIV-1 Immunol. Today 17 1996 239 246
26. J.W. Ponder, and F.M. Richards Use of packing criteria in the enumeration of allowed sequences for different structural classes J. Mol. Biol. 193 1987 775 791
27. F.M. Richards Areas, volumes, packing and protein structure Annu. Rev. Biophys. Bioeng. 6 1977 151 157
28. C.D. Rizzuto, R. Wyatt, N. Hernández-Ramos, Y. Sun, P.D. Kwong, W.A. Hendrickson, and J. Sodroski A conserved HIV gp120 glycoprotein structure involved in chemokine receptor binding Science 280 1998 1949 1953
29. M. Thali, J.P Moore, C. Furman, M. Charles, D.D. Ho, J. Robinson, and J. Sodroski Characterization of conserved human immunodeficiency virus type 1 gp120 neutralization epitopes exposed upon gp120-CD4 binding J. Virol. 67 1993 3978 3988
30. S. Valas, C. Benoit, C. Baudry, G. Perrin, and R.Z. Mamoun Variability and immunogenicity of caprine arthritis-encephalitis virus surface glycoprotein J. Virol. 74 2000 6178 6185
31. R. Wyatt, M. Thali, S. Tilley, A. Pinter, M. Posner, D. Ho, J. Robinson, and J. Sodroski Relationship of the human immunodeficiency virus type 1 gp120 third variable loop to a component of the CD4 binding site in the fourth conserved region J. Virol. 66 1992 6997 7004
32. R. Wyatt, J. Moore, M. Accola, E. Desjardin, J. Robinson, and J. Sodroski Involvement of the V1/V2 variable loop structure in the exposure of human immunodeficiency virus type 1 gp120 epitopes induced by receptor binding J. Virol. 69 1995 5723 5733
33. R. Wyatt, P.D. Kwong, E. Desjardins, R.W. Sweet, J. Robinson, W.A. Hendrickson, and J. Sodroski The antigenic structure of the HIV gp120 envelope glycoprotein Nature 393 1998 705 711
34. S. Xiang, P.D. Kwong, R. Gupta, C.D. Rizzuto, D.J. Casper, R. Wyatt, L. Wang, W.A. Hendrickson, M.L. Doyle, and J. Sodroski Mutagenic stabilization and/or disruption of a CD4-bound state reveals distinct conformations of the human immunodeficiency virus type 1 gp120 envelope glycoprotein J. Virol. 76 2002 9888 9899