In vitro cytotoxicity testing of airborne formaldehyde collected in serum-free culture media

Toxicology and Industrial Health

Volumn 21, Issue 6, 2005, Pages 147-154

  Bakand, S ^a   Hayes, A ^a   Winder, C ^a   Khalil, C ^a   Markovic, B ^a  

^a UNIVERSITY OF NEW SOUTH WALES   (Australia)

Author keywords

air contaminants; cytotoxicity; formaldehyde; in vitro toxicity; MTS (tetrazolium salt) assay

Indexed keywords

FORMALDEHYDE; TETRAZOLIUM;

AIR POLLUTION; ARTICLE; CANCER CELL CULTURE; CELL CULTURE; CELL VIABILITY; CHEMICAL ANALYSIS; CONTROLLED STUDY; CULTURE MEDIUM; CYTOTOXICITY; HEPATOMA CELL; HUMAN; HUMAN CELL; SKIN FIBROBLAST;

AIR POLLUTANTS, OCCUPATIONAL; CELL SURVIVAL; FIBROBLASTS; FORMALDEHYDE; HUMANS; SKIN; TETRAZOLIUM SALTS; TOXICITY TESTS; TUMOR CELLS, CULTURED;

EID: 23844446466     PISSN: 07482337     EISSN: None     Source Type: Journal    
DOI: 10.1191/0748233705th223oa     Document Type: Article

References (31)

1. Alfaro Moreno, E., Martinez, L., Garcia Cuellar, C. et al. 2002: Biologic effects induced in vitro by PM 10 from three different zones of Mexico City. Environmental Health Perspectives 110, 715-720.
2. ATSDR, 1999: Toxicological profile for Formaldehyde. Atlanta: US Department of Health and Human Services, Public Health Service. Agency for Toxic Substances and Disease Registry.
3. Aufderheide, M., Knebel, J. W. and Ritter, D. 2003: Novel approaches for studying pulmonary toxicity in vitro. Toxicology Letters 140-141, 205-211.
4. Blanquart, C., Giuliani, I., Houcine, O. et al. 1995: In vitro exposure of rabbit trachelium to SO2: effects on morphology and ciliarity beating. Toxicology In Vitro 9, 123-132.
5. Chen, L. C., Fang, C. P., Qu, Q. S. et al. 1993: A novel system for the in vitro exposure of pulmonary cells to acid sulfate aerosols. Fundamental and Applied Toxicology 20, 170-176.
6. Clemedson, C. and Ekwall, B. 1999: Overview of the final MEIC results: I. The in vitro-in vitro evaluation. Toxicology In Vitro 13, 657-663.
7. Conolly, R. B., Kimbell, J. S., Janszen, D. B. and Miller, F. J. 2002: Dose response for formaldehyde-induced cytotoxi-city in the human respiratory tract. Regulatory Toxicology and Pharmacology 35, 32-43.
8. Ekwall, B. 1999: Overview of the final MEIC results: II. The in vitro-in vivo evaluation, including the selection of a practical battery of cell tests for prediction of acute lethal blood concentrations in humans. Toxicology In Vitro 13, 665-673.
9. Glowala, M., Mazurek, A., Piddubnyak, V. et al. 2002: HSP70 over expression increases resistance of V79 cells to cytotoxicity of airborne pollutants, but does not protect the mitotic spindle against damage caused by airborne toxins. Toxicology 170, 211-219.
10. Hamers, T., Van Schaardenburg, M. D., Felzel, E. C. et al. 2000: The application of reporter gene assay for the determination of the toxic potency of diffuse air pollution. The Science of the Total Environment 262, 159-174.
11. IARC, 1995: International Agency for Research on Cancer - summaries & evaluations, formaldehyde, vol 62. Retrieved from http://www.inchem.org/documents/iarc/vol62/formal.html (accessed September 2003).
12. IARC, 2004: IARC classifies formaldehyde as carcinogenic to humans. International Agency for Research on Cancer, Press Release, N 153.
13. IPCS, 1989: Formaldehyde. Environmental health criteria, No 89. International Programme on Chemical Safety. Geneva: World Health Organization.
14. Jabbour, A. J., Altman, L. C., Wight, T. N. and Luchtel, D. L. 1998: Ozone alters the distribution of beta1 integrins in cultured primate bronchial epithelial cells. American Journal of Respiratory Cell and Molecular Biology 19, 357-365.
15. Knebel, J. W., Ritter, D. and Aufderheide, M. 1998: Development of an in vitro system for studying effects of native and photochemically transformed gaseous compounds using an air/liquid culture technique. Toxicology Letters 96 -97, 1-11.
16. Lieber, M., Smith, B., Szakal, A. et al. 1976: A continuous tumour-cell line from a human lung carcinoma with properties of type II alveolar epithelial cells. International Journal of Cancer 17, 62-70.
17. Lovschall, H., Eiskjaer, M. and Arenholt-Bindslev, D. 2002: Formaldehyde cytotoxicity in three human cell types assessed in three different assays. Toxicology In Vitro 16, 63-69.
18. Malich, G., Markovic, B. and Winder, C. 1997: The sensitivity and specificity of the MTS tetrazolium assay for detecting the in vitro cytotoxicity of 20 chemicals using human cell lines. Toxicology 124, 179-192.
19. Monticello, T. M., Miller, F. J. and Morgan, K. T. 1991: Regional increases in rat nasal epithelial cell proliferation following acute and subchronic inhalation of formalde-hyde. Toxicology & Applied Pharmacology 111, 409-421.
20. Muckter, H., Zwing, M., Bader, S. et al. 1998: A novel apparatus for the exposure of cultured cells to volatile agents. Journal of Pharmacological and Toxicological Methods 40, 63-69.
21. Newell, G. W. 1983: Overview of formaldehyde. In Gibson, J. E., editor, Formaldehyde toxicity. Washington, DC: Hemisphere Publishing Corporation, 3-15.
22. NIOSH, 1994: NIOSH manual of analytical methods (NMAM), fourth edition. National Institute for Occupational Safety and Health. Retrieved from http://www.cdc.gov/niosh/nmam/nmammenu.html (accessed March 2003).
23. NIOSH, 2002: The registry of toxic effects of chemical substances, formaldehyde, RTECS NO LP8925000. National Institute for Occupational Safety and Health. Retrieved from http://www.cdc.gov/niosh/rtecs/lp882f48.html (accessed September 2003).
24. Promega, CellTiter 96® Aqueous Non-Radioactive Cell Proliferation Assay: Technical Bulletin No 169. Madison, USA: Promega Corporation
25. Ritter, D., Knebel, J. W. and Aufderheide, M. 2001: In vitro exposure of isolated cells to native gaseous compounds - development and validation of an optimized system for human lung cells. Experimental and Toxicologic Pathology 53, 373-386.
26. Rusznak, C., Devalia, J. L., Sapsford, R. J. and Davies, R. J., 1996: Ozone-induced mediator release from human bronchial epithelial cells in vitro and the influence of nedocromil sodium. European Respiratory Journal 9, 2298-2305.
27. Saltzman, B. E. 1997: Preparation of known concentration of air contaminants. In Dinardi, S. R., editor, The occupational environment - its evaluation and control. Fairfax, VA: American Industrial Hygienists Association, 131-154.
28. Van Der Zee, J., Dubbelman, T. M. A. R., Raap, T. K. and Van Steveninck, J. 1987: Toxic effects of ozone on murine L929 fibroblasts. Enzyme inactivation and glutathion depletion. Biochemical Journal 242, 707-712.
29. WHO, 2002: Formaldehyde, Concise International Chemical Assessment Document, No 40. Geneva: World Health Organization.
30. Wilmer, J. W., Woutersen, R. A., Appelman, L. M. et al. 1989: Subchronic (13-week) inhalation toxicity study of formal-dehyde in male rats: 8-hour intermittent versus 8-hour continuous exposure. Toxicology Letters 47, 287-293.
31. Yamaguchi, T. and Yamazaki, H. 2001: Cytotoxicity of airborne particulates sampled roadside in rodent and human lung fibroblasts. Journal of Health Science 47, 272-277.