Targeting normal and neoplastic tissues in the rat jejunum and colon with boronated, cationic acrylamide copolymers

Journal of Controlled Release

Volumn 106, Issue 1-2, 2005, Pages 14-25

  Azab, Abdel Kareem ^a   Srebnik, Morris ^a   Doviner, Victoria ^b   Rubinstein, Abraham ^a  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^b HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

Author keywords

Acrylamide polymer; Boron neutron capture therapy; Colorectal cancer

Indexed keywords

CONCENTRATION (PROCESS); ELECTROSTATICS; MONOMERS; PH; POLYMERS; POSITIVE IONS; TISSUE;

ACRYLAMIDE POLYMER; BORON NEUTRON CAPTURE THERAPY (BNCT); COLORECTAL CANCER; RAT JEJUNUM;

COPOLYMERS;

BORON DERIVATIVE; COPOLYMER; MAGNESIUM ION; MUCIN; N ACRYLOYL 3 AMINOPHENYLBORONIC ACID; N ACRYLOYLDIAMINOETHANE; POLYACRYLAMIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY DISTRIBUTION; CHEMICAL INTERACTION; COLON; COLON POLYP; COMPARATIVE STUDY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG TARGETING; DRUG TISSUE LEVEL; DRUG UPTAKE; ELECTRICITY; INTESTINE EPITHELIUM; INTESTINE POLYP; IONIZATION; JEJUNUM; MICROENVIRONMENT; NEOPLASM; NEUTRON CAPTURE THERAPY; NONHUMAN; PH MEASUREMENT; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT;

1,2-DIMETHYLHYDRAZINE; ACRYLAMIDE; ANIMALS; BORON; BORON NEUTRON CAPTURE THERAPY; BORONIC ACIDS; CARCINOGENS; CATIONS; COLON; COLONIC NEOPLASMS; DRUG CARRIERS; INTESTINAL MUCOSA; JEJUNUM; MUCINS; POLYMERS; RATS; RATS, INBRED STRAINS; TISSUE ADHESIVES;

EID: 23744513109     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2005.03.015     Document Type: Article

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