Synthesis of macrocyclic scaffolds from natural products and their utilization for solid-phase chemistry

Synthesis

Volumn , Issue 12, 2005, Pages 2015-2021

  Grosche, Philipp ^a   Akyel, Kayhan Gabriel ^a   Marzinzik, Andreas L ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

Author keywords

Combinatorial chemistry; Natural products; Solid phase synthesis

Indexed keywords

CHEMISTRY; SCAFFOLDS; SOLIDS;

COMBINATORIAL CHEMISTRY; NATURAL PRODUCTS; SOLID-PHASE CHEMISTRY; SOLID-PHASE SYNTHESIS;

SYNTHESIS (CHEMICAL);

1 [12,13 DIHYDROXY 1,2 DIMETHOXY 7 METHYL 4 (3 NITROBENZYLOXY) 5 OXO 5,8,9,10,11,12,13,14,15,16 DECAHYDRO 7H 6 OXA BENZOCYCLOTETRADECEN 11 YL] 3 (2 FLUOROPHENYL) UREA; 1 [4 ALLYLOXY 12,13 DIHYDROXY 1,2 DIMETHOXY 7 METHYL 5 OXO 5,8,9,10,11,12,13,14,15,16 DECAHYDRO 7H 6 OXA BENZOCYCLOTETRADECEN 11 YL) 3 (3 TRIFLUOROMETHYL PHENYL)UREA]; 1 TERT BUTYL 3 [12,13 DIHYDROXY 1,2 DIMETHOXY 7 METHYL 4 (3 NITROBENZYLOXY) 5 OXO 5,8,9,10,11,12,13,14,15,16 DECAHYDRO 7H 6 OXA BENZOCYCLOTETRADECEN 11 YLUREA; [4 ALLYLOXY 12,13 DIHYDROXY 1,2 DIMETHOXY 7 METHYL 5 OXO 5,8,9,10,11,12,13,14,15,16 DECAHYDRO 7H 6 OXA BENZOCYCLOTETRADECEN 11 YL]AMIDE THIOPHENE 2 CARBOXYLIC ACID; MACROCYCLIC COMPOUND; N [4 ALLYLOXY 12,13 DIHYDROXY 1,2 DIMETHOXY 7 METHYL 5 OXO 5,8,9,10,11,12,13,14,15,16 DECAHYDRO 7H 6 OXA BENZOCYCLOTETRADECEN 11 YL]BENZAMIDE; UNCLASSIFIED DRUG; UREA DERIVATIVE; ZEARALENONE;

ALKYLATION; ARTICLE; CATALYSIS; DERIVATIZATION; FUNGAL STRAIN; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROGENATION; SOLID; SYNTHESIS;

EID: 23744472085     PISSN: 00397881     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2005-869969     Document Type: Article

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