Functional imaging in small animals using X-ray computed tomography - Study of physiologic measurement reproducibility

IEEE Transactions on Medical Imaging

Volumn 24, Issue 7, 2005, Pages 832-843

  Krishnamurthi, Ganapathy ^a   Stantz, Keith M ^b   Steinmetz, Rosemary ^b   Gattone, Vincent H ^b   Cao, Minsong ^a   Hutchins, Gary D ^b   Liang, Yun ^b  

^a PURDUE UNIVERSITY   (United States)

^b INDIANA UNIVERSITY   (United States)

Author keywords

Compartmental model; Functional computed tomography; PKD; Renal physiology

Indexed keywords

BLOOD; COMPUTERIZED TOMOGRAPHY; HYDROPHILICITY; PHYSIOLOGY; SCANNING; X RAYS;

COMPARTMENTAL MODEL; CONTRAST AGENT (CA); FUNCTIONAL COMPUTED TOMOGRAPHY; RENAL PHYSIOLOGY;

MEDICAL IMAGING;

CONTRAST MEDIUM;

ALGORITHM; ANIMAL; ANIMAL DISEASE; ARTICLE; BIOLOGICAL MODEL; COMPUTER ASSISTED DIAGNOSIS; COMPUTER ASSISTED TOMOGRAPHY; COMPUTER SIMULATION; EVALUATION; FEASIBILITY STUDY; IMAGE QUALITY; KIDNEY; MALE; METHODOLOGY; MOUSE; NUDE MOUSE; RADIOGRAPHY; REPRODUCIBILITY; SAMPLE SIZE; SENSITIVITY AND SPECIFICITY; STATISTICAL MODEL;

ALGORITHMS; ANIMALS; COMPUTER SIMULATION; CONTRAST MEDIA; FEASIBILITY STUDIES; KIDNEY; MALE; MICE; MICE, NUDE; MODELS, BIOLOGICAL; MODELS, STATISTICAL; RADIOGRAPHIC IMAGE ENHANCEMENT; RADIOGRAPHIC IMAGE INTERPRETATION, COMPUTER-ASSISTED; REPRODUCIBILITY OF RESULTS; SAMPLE SIZE; SENSITIVITY AND SPECIFICITY; TOMOGRAPHY, X-RAY COMPUTED;

EID: 23744456949     PISSN: 02780062     EISSN: None     Source Type: Journal    
DOI: 10.1109/TMI.2005.851385     Document Type: Article

References (37)

1. V. E. Torres, "New insights into polycystic kidney disease and its treatment," Curr. Opin. Nephrol. Hypertens., vol. 7, no. 2, pp. 159-169, Mar. 1998.
2. B. D. Cowley Jr., "Recent advances in understanding the pathogenesis of polycystic kidney disease: Therapeutic implications," Drugs, vol. 64, no. 12, pp. 1285-1294, 2004.
3. T. Yamaguchi, J. C. Pelling, N. T. Ramaswamy, J. W. Eppler, D. P. Wallace, S. Nagao, L. A. Rome, L. P. Sullivan, and J. J. Grantham, "cAMP stimulates the in vitro proliferation of renal cyst epithelial cells by activating the extracellular signal-regulated kinase pathway," Kidney Int., vol. 57, no. 4, pp. 1460-1471, Apr. 2000.
4. T. Yamaguchi, S. Nagao, H. Takahashi, M. Ye, and J. J. Grantham, "Cyst fluid from a murine model of polycystic kidney disease stimulates fluid secretion, cyclic adenosine monophosphate accumulation, and cell proliferation by Madin-Darby canine kidney cells in vitro," Am. J. Kidney Dis., vol. 25, no. 3, pp. 471-477, Mar. 1995.
5. K. Hanaoka, O. Devuyst, E. M. Schwiebert, P. D. Wilson, and W. B. Guggino, "A role for CFTR in human autosomal dominant polycystic kidney disease," Am. J. Physiol., pt. 1, vol. 270, no. 1, pp. C389-C399, Jan. 1996.
6. C. J. Davidow, R. L. Maser, L. A. Rome, J. P. Calvet, and J. J. Grantham, "The cystic fibrosis transmembrane conductance regulator mediates transepithelial fluid secretion by human autosomal dominant polycystic kidney disease epithelium in vitro," Kidney Int., vol. 50, no. 1, pp. 208-218, Jul. 1996.
7. Q. Qian, P. C. Harris, and V. E. Torres, "Treatment prospects for autosomal-dominant polycystic kidney disease," Kidney Int., vol. 59, no. 6, pp. 2005-2022, Jun. 2001.
8. J. Grantham, B. Cowley Jr., and V. Torres, "Progression of autosomal dominant polycystic kidney disease (ADPKD) to renal failure," in The Kidney: Physiology and Pathophysiology, 2nd ed, D. Seldin and G. Giebisch, Eds. Baltimore, MD: Lippincott Williams & Wilkins, 2000, pp. 2513-2536.
9. B. Hocher, R. Zart, A. Schwarz, V. Vogt, C. Braun, C. Thone-Reineke, N. Braun, H. H. Neumayer, K. Koppenhagen, C. Bauer, and P. Rohmeiss, "Renal endothelin system in polycystic kidney disease," J. Am. Soc. Nephrol., vol. 9, no. 7, pp. 1169-1177, Jul. 1998.
10. K. A. Nath, "Tubulointerstitial changes as a major determinant in the progression of renal damage," Am. J. Kidney Dis., vol. 20, no. 1, pp. 1-17, Jul. 1992.
11. T. M. Kennefick, M. A. Al Nimri, T. T. Oyama, M. M. Thompson, F. J. Kelly, J. G. Chapman, and S. Anderson, "Hypertension and renal injury in experimental polycystic kidney disease," Kidney Int., vol. 56, no. 6, pp. 2181-2190, Dec. 1999.
12. M. A. AI Nimri, R. Komers, T. T. Oyama, A. R. Subramanya, J. N. Lindsley, and S. Anderson, "Endothelial-derived vasoactive mediators in polycystic kidney disease," Kidney Int., vol. 63, no. 5, pp. 1776-1784, May 2003.
13. R. Zhou, S. Pickup, T. E. Yankeelov, C. S. Springer Jr., and J. D. Glickson, "Simultaneous measurement of arterial input function and tumor pharmacokinetics in mice by dynamic contrast enhanced imaging: Effects of transcytolemmal water exchange," Magn. Reson. Med., vol. 52, no. 2, pp. 248-257, Aug. 2004.
14. L. Bogin, R. Margalit, J. Mispelter, and H. Degani, "Parametric imaging of tumor perfusion using flow- and permeability-limited tracers," J. Magn. Reson. Imag., vol. 16, no. 3, pp. 289-299, Sep. 2002.
15. K. M. Donahue, R. M. Weisskoff, and D. Burstein, "Water diffusion and exchange as they influence contrast enhancement," J. Magn. Reson. Imag., vol. 7, no. 1, pp. 102-110, Jan. 1997.
16. K. M. Donahue, R. M. Weisskoff, D. A. Chesler, K. K. Kwong, A. A. Bogdanov Jr., J. B. Mandeville, and B. R. Rosen, "Improving MR quantification of regional blood volume with intravascular T 1 contrast agents: Accuracy, precision, and water exchange," Magn. Reson. Med., vol. 36, no. 6, pp. 858-867, Dec. 1996.
17. R. M. Judd, S. B. Reeder, and K. May-Newman, "Effects of water exchange on the measurement of myocardial perfusion using paramagnetic contrast agents," Magn. Reson. Med., vol. 41. no. 2, pp. 334-342, Feb. 1999.
18. A. L. Goertzen, A. K. Meadors, R. W. Silverman, and S. R. Cherry, "Simultaneous molecular and anatomical imaging of the mouse in vivo," Phys. Med. Biol., vol. 47, no. 24, pp. 4315-4328, Dec. 2002.
19. G. D. Hutchins, N. Rouze, K. L. Stone, G. Krishnamurthi, and Y. Liang, "Initial imaging experience with IndyPET II," J. Nucl. Med., vol. 43, no. 5, p. 59P, May 2002.
20. R. Weissleder and V. Ntziachristos, "Shedding light onto live molecular targets," Nat. Med., vol. 9, no. 1, pp. 123-128, Jan. 2003.
21. S. R. Cherry, "In vivo molecular and genomic imaging: New challenges for imaging physics," Phys. Med. Biol., vol. 49, no. 3, pp. R13-R48, Feb. 2004.
22. V. Ntziachristos, C. H. Tung, C. Bremer, and R. Weissleder, "Fluorescence molecular tomography resolves protease activity in vivo," Nat. Med., vol. 8, no. 7, pp. 757-760, Jul. 2002.
23. R. K. Jain, "Delivery of molecular and cellular medicine to solid tumors," Microcirculation-London, vol. 4, no. 1, pp. 3-23, Mar. 1997.
24. _, "Determinants of tumor blood-flow - A review," Cancer Res., vol. 48, no. 10, pp. 2641-2658, May 1988.
25. _, "Transport of molecules in the tumor interstitium - A review," Cancer Res., vol. 47, no. 12, pp. 3039-3051, Jun. 1987.
26. H. Anderson, P. Price, M. Blomley, M. O. Leach, and P. Workman, "Measuring changes in human tumour vasculature in response to therapy using functional imaging techniques," Br. J. Cancer, vol. 85, no. 8, pp. 1085-1093, Oct. 2001.
27. K. Miles, P. H. Dawson, and M. Blomley, Functional Computed Tomography. Oxford, U.K.: Isis Medical Media, 1997.
28. T. G. Purdie, E. Henderson, and T. Y. Lee, "Functional CT imaging of angiogenesis in rabbit VX2 soft-tissue tumour," Phys. Med. Biol., vol. 46, no. 12, pp. 3161-3175, Dec. 2001.
29. G. Brix, M. L. Bahner, U. Hoffmann, A. Horvath, and W. Schreiber, "Regional blood flow, capillary permeability, and compartmental volumes: Measurement with dynamic CT - Initial experience," Radiology, vol. 210, no. 1, pp. 269-276, Jan. 1999.
30. K. M. Stantz, Y. Liang, and G. Hutchins, "Kinematic modeling and its implication in longitudinal chemotherapy study of tumor physiology: Ovarian xenograft mouse model and contrast-enhanced dynamic CT. 5369," Proc. SPIE (Medical Imaging 2004), pp. 769-779, 2004.
31. L. T. Baxter, H. Zhu, D. G. Mackensen, and R. K. Jain, "Physiologically based pharmacokinetic model for specific and nonspecific monoclonal antibodies and fragments in normal tissues and human tumor xenografts in nude mice," Cancer Res., vol. 54, no. 6, pp. 1517-1528, Mar. 1994.
32. L. T. Baxter, H. Zhu, D. G. Mackensen, W. F. Butler, and R. K. Jain, "Biodistribution of monoclonal antibodies: Scale-up from mouse to human using a physiologically based pharmacokinetic model," Cancer Res., vol. 55, no. 20, pp. 4611-4622, Oct. 1995.
33. S. K. Sarin, C. Sabba, and R. J. Groszmann, "Splanchnic and systemic hemodynamics in mice using a radioactive microsphere technique," Am. J. Physiol., pt. 1, vol. 258, no. 3, pp. G365-G369, Mar. 1990.
34. J. N. Lorenz, "A practical guide to evaluating cardiovascular, renal, and pulmonary function in mice," Am. J. Physiol. Regul. Integr. Comp. Physiol., vol. 282, no. 6, pp. R1565-R1582, Jun. 2002.
35. Y. Liang, K. M. Stantz, G. Krishnamurthi, R. Steinmetz, and G. D. Hutchins, "Development of contrast-enhanced rodent imaging using functional CT," Proc. SPIE (Medical Imaging 2003), vol. 5031, pp. 140-148, 2003.
36. B. Hocher, R. Zart, A. Schwarz, V. Vogt, C. Braun, C. Thone-Reineke, N. Braun, H. H. Neumayer, K. Koppenhagen, C. Bauer, and P. Rohmeiss, "Renal endothelin system in polycystic kidney disease," J. Am. Soc. Nephrol., vol. 9, no. 7, pp. 1169-1177, Jul. 1998.
37. T. M. Kennefick, M. A. Al Nimri, T. T. Oyama, M. M. Thompson, F. J. Kelly, J. G. Chapman, and S. Anderson, "Hypertension and renal injury in experimental polycystic kidney disease," Kidney Int., vol. 56, no. 6, pp. 2181-2190, Dec. 1999.