In vivo delivery of BCNU from a MEMS device to a tumor model

Journal of Controlled Release

Volumn 106, Issue 1-2, 2005, Pages 138-145

  Li, Yawen ^a   Duc, Hong Linh Ho ^a   Tyler, Betty ^b   Williams, Tiffany ^b   Tupper, Malinda ^a   Langer, Robert ^a   Brem, Henry ^b   Cima, Michael J ^a  

^a Massachusetts Institute of Technology Cambridge   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

BCNU; Drug delivery; Microelectromechanical systems (MEMS); Release kinetics; Tumor

Indexed keywords

CHEMOTHERAPY; DRUG THERAPY; GROWTH KINETICS; MICROELECTROMECHANICAL DEVICES; SILICON; SUBSTRATES;

CHEMOTHERAPEUTIC AGENT; ELECTROCHEMICAL DISSOLUTION; EQUIPOTENT INJECTIONS; RELEASE KINETICS; THERAPEUTIC AGENTS;

CONTROLLED DRUG DELIVERY;

CARMUSTINE; GOLD; MACROGOL; SILICON;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; ARTIFICIAL MEMBRANE; CANCER INHIBITION; CONTROLLED STUDY; DOSE RESPONSE; DRUG DELIVERY MICROELECTROMECHANICAL SYSTEM; DRUG DELIVERY SYSTEM; DRUG POTENCY; DRUG RELEASE; ELECTROCHEMISTRY; EXPERIMENTAL MODEL; FEMALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; ANTINEOPLASTIC AGENTS, ALKYLATING; CARBON RADIOISOTOPES; CARMUSTINE; CHEMISTRY, PHARMACEUTICAL; DRUG DELIVERY SYSTEMS; DRUG PACKAGING; ELECTROCHEMISTRY; FEMALE; GLASS; GLIOSARCOMA; MINIATURIZATION; NEOPLASM TRANSPLANTATION; NEOPLASMS, EXPERIMENTAL; POLYETHYLENE GLYCOLS; RATS; RATS, INBRED F344; TUMOR BURDEN;

EID: 23744452913     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2005.04.009     Document Type: Article

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