메뉴 건너뛰기




Volumn 1, Issue 4, 2004, Pages 441-448

Mechanisms of neuropathic pain: The role of cytokines

Author keywords

[No Author keywords available]

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ADALIMUMAB; CYTOKINE; ETANERCEPT; INFLIXIMAB; INTERLEUKIN 1 ANTIBODY; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 6 ANTIBODY; RECOMBINANT ANTIBODY; RECOMBINANT INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA ANTIBODY;

EID: 23744447366     PISSN: 17406765     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ddmec.2004.11.018     Document Type: Review
Times cited : (19)

References (61)
  • 1
    • 0032103115 scopus 로고    scopus 로고
    • Enkelytin and opioid peptide association in invertebrates and vertebrates: Immune activation and pain
    • Stefano, G.B. et al. (1998) Enkelytin and opioid peptide association in invertebrates and vertebrates: immune activation and pain. Immunol. Today 19, 265-268
    • (1998) Immunol. Today , vol.19 , pp. 265-268
    • Stefano, G.B.1
  • 2
    • 0003731855 scopus 로고    scopus 로고
    • Cytokines and neuropathic pain
    • (Hansson, P., Fields, H., Hill, R., Marchettini, P., eds), IASP press
    • Sommer, C. (2001) Cytokines and neuropathic pain. In Neuropathic Pain: Pathophysiology and Treatment (Hansson, P., Fields, H., Hill, R., Marchettini, P., eds), pp. 37-62, IASP press
    • (2001) Neuropathic Pain: Pathophysiology and Treatment , pp. 37-62
    • Sommer, C.1
  • 3
    • 0345561564 scopus 로고    scopus 로고
    • Nerve injury, axonal degeneration and neural regeneration: Basic insights
    • Stoll, G. and Muller, H.W. (1999) Nerve injury, axonal degeneration and neural regeneration: basic insights. Brain Pathol. 9, 313-325
    • (1999) Brain Pathol. , vol.9 , pp. 313-325
    • Stoll, G.1    Muller, H.W.2
  • 4
    • 0030217998 scopus 로고    scopus 로고
    • Schwann cells produce tumor necrosis factor alpha: Expression in injured and non-injured nerves
    • Wagner, R. and Myers, R.R. (1996) Schwann cells produce tumor necrosis factor alpha: expression in injured and non-injured nerves. Neuroscience 73, 625-629
    • (1996) Neuroscience , vol.73 , pp. 625-629
    • Wagner, R.1    Myers, R.R.2
  • 5
    • 0034994231 scopus 로고    scopus 로고
    • Pro- And anti-inflammatory cytokine gene expression in rat sciatic nerve chronic constriction injury model of neuropathic pain
    • Okamoto, K. et al. (2001) Pro- and anti-inflammatory cytokine gene expression in rat sciatic nerve chronic constriction injury model of neuropathic pain. Exp. Neurol. 169, 386-391
    • (2001) Exp. Neurol. , vol.169 , pp. 386-391
    • Okamoto, K.1
  • 6
    • 1542500972 scopus 로고    scopus 로고
    • The extent of cytokine induction in peripheral nerve lesions depends on the mode of injury and NMDA receptor signaling
    • Kleinschnitz, C. et al. (2004) The extent of cytokine induction in peripheral nerve lesions depends on the mode of injury and NMDA receptor signaling. J. Neuroimmunol. 149, 77-83
    • (2004) J. Neuroimmunol. , vol.149 , pp. 77-83
    • Kleinschnitz, C.1
  • 7
    • 2942612995 scopus 로고    scopus 로고
    • Wallerian degeneration after crush or chronic constriction injury of rodent sciatic nerve is associated with a depletion of endoneurial interleukin-10 protein
    • George, A. et al. (2004) Wallerian degeneration after crush or chronic constriction injury of rodent sciatic nerve is associated with a depletion of endoneurial interleukin-10 protein. Exp. Neurol. 188, 187-191
    • (2004) Exp. Neurol. , vol.188 , pp. 187-191
    • George, A.1
  • 8
    • 0029029582 scopus 로고
    • Induction of interleukin-6 in axotomized sensory neurons
    • Murphy, P.G. et al. (1995)Induction of interleukin-6 in axotomized sensory neurons. J. Neurosci. 15, 5130-5138
    • (1995) J. Neurosci. , vol.15 , pp. 5130-5138
    • Murphy, P.G.1
  • 9
    • 0037294433 scopus 로고    scopus 로고
    • Selective increase of tumour necrosis factor-alpha in injured and spared myelinated primary afferents after chronic constrictive injury of rat sciatic nerve
    • Schäfers, M. et al. (2003) Selective increase of tumour necrosis factor-alpha in injured and spared myelinated primary afferents after chronic constrictive injury of rat sciatic nerve. Eur. J. Neurosci. 17, 791-804
    • (2003) Eur. J. Neurosci. , vol.17 , pp. 791-804
    • Schäfers, M.1
  • 10
    • 0030751245 scopus 로고    scopus 로고
    • Cytokine and growth factor immunohistochemical spinal profiles in two animal models of mononeuropathy
    • DeLeo, J.A. et al. (1997) Cytokine and growth factor immunohistochemical spinal profiles in two animal models of mononeuropathy. Brain Res. 759, 50-57
    • (1997) Brain Res. , vol.759 , pp. 50-57
    • DeLeo, J.A.1
  • 11
    • 0032570035 scopus 로고    scopus 로고
    • Increase of interleukin-6 mRNA in the spinal cord following peripheral nerve injury in the rat: Potential role of IL-6 in neuropathic pain
    • Arruda, J.L. et al. (1998) Increase of interleukin-6 mRNA in the spinal cord following peripheral nerve injury in the rat: potential role of IL-6 in neuropathic pain. Brain Res. Mol. Brain Res. 62, 228-235
    • (1998) Brain Res. Mol. Brain Res. , vol.62 , pp. 228-235
    • Arruda, J.L.1
  • 12
    • 0035888084 scopus 로고    scopus 로고
    • Nerve injury proximal or distal to the DRG induces similar spinal glial activation and selective cytokine expression but differential behavioral responses to pharmacologic treatment
    • Winkelstein, B.A. et al. (2001) Nerve injury proximal or distal to the DRG induces similar spinal glial activation and selective cytokine expression but differential behavioral responses to pharmacologic treatment. J. Comp. Neurol 439, 127-139
    • (2001) J. Comp. Neurol , vol.439 , pp. 127-139
    • Winkelstein, B.A.1
  • 13
    • 0033546760 scopus 로고    scopus 로고
    • Brain-derived TNFalpha mediates neuropathic pain
    • Ignatowski, T.A. et al. (1999) Brain-derived TNFalpha mediates neuropathic pain. Brain Res. 841, 70-77
    • (1999) Brain Res. , vol.841 , pp. 70-77
    • Ignatowski, T.A.1
  • 14
    • 0034677593 scopus 로고    scopus 로고
    • Brain-derived TNFalpha: Involvement in neuroplastic changes implicated in the conscious perception of persistent pain
    • Covey, W.C. et al. (2000) Brain-derived TNFalpha: involvement in neuroplastic changes implicated in the conscious perception of persistent pain. Brain Res. 859, 113-122
    • (2000) Brain Res. , vol.859 , pp. 113-122
    • Covey, W.C.1
  • 15
    • 0038748399 scopus 로고    scopus 로고
    • Glial proinflammatory cytokines mediate exaggerated pain states: Implications for clinical pain
    • Watkins, L.R. et al. (2003) Glial proinflammatory cytokines mediate exaggerated pain states: implications for clinical pain. Adv. Exp. Med. Biol. 521, 1-21
    • (2003) Adv. Exp. Med. Biol. , vol.521 , pp. 1-21
    • Watkins, L.R.1
  • 16
    • 0030474099 scopus 로고    scopus 로고
    • Endoneurial injection of TNF-alpha produces neuropathic pain behaviors
    • Wagner, R. and Myers, R.R. (1996) Endoneurial injection of TNF-alpha produces neuropathic pain behaviors. Neuroreport 7, 2897-2901
    • (1996) Neuroreport , vol.7 , pp. 2897-2901
    • Wagner, R.1    Myers, R.R.2
  • 17
    • 0030770623 scopus 로고    scopus 로고
    • Tumour necrosis factor-alpha induces ectopic activity in nociceptive primary afferent fibres
    • Sorkin, L.S. et al. (1997) Tumour necrosis factor-alpha induces ectopic activity in nociceptive primary afferent fibres. Neuroscience 81, 255-262
    • (1997) Neuroscience , vol.81 , pp. 255-262
    • Sorkin, L.S.1
  • 18
    • 0031884592 scopus 로고    scopus 로고
    • Anti-inflammatory interleukin-10 therapy in CCI neuropathy decreases thermal hyperalgesia, macrophage recruitment, and endoneurial TNF-alpha expression
    • Wagner, R. et al. (1998) Anti-inflammatory interleukin-10 therapy in CCI neuropathy decreases thermal hyperalgesia, macrophage recruitment, and endoneurial TNF-alpha expression. Pain 74, 35-42
    • (1998) Pain , vol.74 , pp. 35-42
    • Wagner, R.1
  • 19
    • 0003012174 scopus 로고    scopus 로고
    • Hyperalgesia from subcutaneous cytokines
    • (Watkins, L.R. and Maier, S.F., eds), Birkhäuser
    • Poole, S. et al. (1999) Hyperalgesia from subcutaneous cytokines. In Cytokines and Pain (Watkins, L.R. and Maier, S.F., eds), pp. 59-87, Birkhäuser
    • (1999) Cytokines and Pain , pp. 59-87
    • Poole, S.1
  • 20
    • 9244259139 scopus 로고    scopus 로고
    • Herpes vector-mediated gene transfer in treatment of diseases of the nervous system
    • Glorioso, J.C. and Fink, D.J. (2004) Herpes vector-mediated gene transfer in treatment of diseases of the nervous system. Annu. Rev. Microbiol. 58, 253-271
    • (2004) Annu. Rev. Microbiol. , vol.58 , pp. 253-271
    • Glorioso, J.C.1    Fink, D.J.2
  • 21
    • 0037129964 scopus 로고    scopus 로고
    • Interleukin-2 gene therapy of chronic neuropathic pain
    • Yao, M.Z. et al. (2002) Interleukin-2 gene therapy of chronic neuropathic pain. Neuroscience 112, 409-416
    • (2002) Neuroscience , vol.112 , pp. 409-416
    • Yao, M.Z.1
  • 22
    • 0035857748 scopus 로고    scopus 로고
    • Intrathecal interleukin-1 receptor antagonist in combination with soluble tumor necrosis factor receptor exhibits an anti-allodynic action in a rat model of neuropathic pain
    • Sweitzer, S. et al. (2001) Intrathecal interleukin-1 receptor antagonist in combination with soluble tumor necrosis factor receptor exhibits an anti-allodynic action in a rat model of neuropathic pain. Neuroscience 103, 529-539
    • (2001) Neuroscience , vol.103 , pp. 529-539
    • Sweitzer, S.1
  • 23
    • 0041655944 scopus 로고    scopus 로고
    • Spinal interleukin-6 (IL-6) inhibits nociceptive transmission following neuropathy
    • Flatters, S.J. et al. (2003) Spinal interleukin-6 (IL-6) inhibits nociceptive transmission following neuropathy. Brain Res. 984, 54-62
    • (2003) Brain Res. , vol.984 , pp. 54-62
    • Flatters, S.J.1
  • 24
    • 0037320840 scopus 로고    scopus 로고
    • Spinal glia and proinflammatory cytokines mediate mirror-image neuropathic pain in rats
    • Milligan, E.D. et al. (2003) Spinal glia and proinflammatory cytokines mediate mirror-image neuropathic pain in rats. J. Neurosci. 23, 1026-1040
    • (2003) J. Neurosci. , vol.23 , pp. 1026-1040
    • Milligan, E.D.1
  • 25
    • 0038324344 scopus 로고    scopus 로고
    • Effects of neutralizing antibodies to tumor necrosis factor-alpha on nucleus pulposus-induced abnormal nociresponses in rat dorsal horn neurons
    • Onda, A. et al. (2003) Effects of neutralizing antibodies to tumor necrosis factor-alpha on nucleus pulposus-induced abnormal nociresponses in rat dorsal horn neurons. Spine 28, 967-972
    • (2003) Spine , vol.28 , pp. 967-972
    • Onda, A.1
  • 26
    • 0027977895 scopus 로고
    • Cutaneous hyperalgesia induced by peripheral injection of interleukin-1β in the rat
    • Fukuoka, H. et al. (1994) Cutaneous hyperalgesia induced by peripheral injection of interleukin-1β in the rat. Brain Res. 657, 133-140
    • (1994) Brain Res. , vol.657 , pp. 133-140
    • Fukuoka, H.1
  • 27
    • 0034663315 scopus 로고    scopus 로고
    • Involvement of the proinflammatory cytokines tumor necrosis factor-alpha, IL-1beta, and IL-6 but not IL-8 in the development of heat hyperalgesia: Effects on heat-evoked calcitonin gene-related peptide release from rat skin
    • Opree, A. and Kress, M. (2000) Involvement of the proinflammatory cytokines tumor necrosis factor-alpha, IL-1beta, and IL-6 but not IL-8 in the development of heat hyperalgesia: effects on heat-evoked calcitonin gene-related peptide release from rat skin. J. Neurosci. 20, 6289-6293
    • (2000) J. Neurosci. , vol.20 , pp. 6289-6293
    • Opree, A.1    Kress, M.2
  • 28
    • 0036794671 scopus 로고    scopus 로고
    • IL-1 beta potentiates heat-activated currents in rat sensory neurons: Involvement of IL-1RI, tyrosine kinase, and protein kinase C
    • Obreja, O. et al. (2002) IL-1 beta potentiates heat-activated currents in rat sensory neurons: involvement of IL-1RI, tyrosine kinase, and protein kinase C. FASEB J. 16, 1497-1503
    • (2002) FASEB J. , vol.16 , pp. 1497-1503
    • Obreja, O.1
  • 29
    • 0033963153 scopus 로고    scopus 로고
    • Nociceptive and inflammatory effects of subcutaneous TNFalpha
    • Junger, H. and Sorkin, L.S. (2000) Nociceptive and inflammatory effects of subcutaneous TNFalpha. Pain 85, 145-151
    • (2000) Pain , vol.85 , pp. 145-151
    • Junger, H.1    Sorkin, L.S.2
  • 30
    • 0035869638 scopus 로고    scopus 로고
    • Reduction of potassium currents and phosphatidylinositol 3-kinase-dependent AKT phosphorylation by tumor necrosis factor-(alpha) rescues axotomized retinal ganglion cells from retrograde cell death in vivo
    • Diem, R. et al. (2001) Reduction of potassium currents and phosphatidylinositol 3-kinase-dependent AKT phosphorylation by tumor necrosis factor-(alpha) rescues axotomized retinal ganglion cells from retrograde cell death in vivo. J. Neurosci. 21, 2058-2066
    • (2001) J. Neurosci. , vol.21 , pp. 2058-2066
    • Diem, R.1
  • 31
    • 0036715218 scopus 로고    scopus 로고
    • Acute topical application of tumor necrosis factor alpha evokes protein kinase A-dependent responses in rat sensory neurons
    • Zhang, J.M. et al. (2002) Acute topical application of tumor necrosis factor alpha evokes protein kinase A-dependent responses in rat sensory neurons. J. Neurophysiol. 88, 1387-1392
    • (2002) J. Neurophysiol. , vol.88 , pp. 1387-1392
    • Zhang, J.M.1
  • 32
    • 17144451153 scopus 로고    scopus 로고
    • Increased sensitivity of injured and adjacent uninjured rat primary sensory neurons to exogenous tumor necrosis factor-alpha after spinal nerve ligation
    • Schäfers, M. et al. (2003) Increased sensitivity of injured and adjacent uninjured rat primary sensory neurons to exogenous tumor necrosis factor-alpha after spinal nerve ligation. J. Neurosci. 23, 3028-3038
    • (2003) J. Neurosci. , vol.23 , pp. 3028-3038
    • Schäfers, M.1
  • 33
    • 0036144288 scopus 로고    scopus 로고
    • TNF-alpha receptors simultaneously activate Ca2+ mobilisation and stress kinases in cultured sensory neurones
    • Pollock, J. et al. (2002) TNF-alpha receptors simultaneously activate Ca2+ mobilisation and stress kinases in cultured sensory neurones. Neuropharmacology 42, 93-106
    • (2002) Neuropharmacology , vol.42 , pp. 93-106
    • Pollock, J.1
  • 34
    • 0345701254 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha induces mechanical allodynia after spinal nerve ligation by activation of p38 MAPK in primary sensory neurons
    • Schäfers, M. et al. (2003) Tumor necrosis factor-alpha induces mechanical allodynia after spinal nerve ligation by activation of p38 MAPK in primary sensory neurons. J. Neurosci. 23, 2517-2521
    • (2003) J. Neurosci. , vol.23 , pp. 2517-2521
    • Schäfers, M.1
  • 35
    • 0023471275 scopus 로고
    • Interleukin-1 regulates synthesis of nerve growth factor in non-neuronal cells of rat sciatic nerve
    • Lindholm, D. et al. (1987) Interleukin-1 regulates synthesis of nerve growth factor in non-neuronal cells of rat sciatic nerve. Nature 330, 658-659
    • (1987) Nature , vol.330 , pp. 658-659
    • Lindholm, D.1
  • 36
    • 0028982492 scopus 로고
    • Contribution of interleukin-1 beta to the inflammation-induced increase in nerve growth factor levels and inflammatory hyperalgesia
    • Safieh-Garabedian, B. et al. (1995) Contribution of interleukin-1 beta to the inflammation-induced increase in nerve growth factor levels and inflammatory hyperalgesia. Br. J. Pharmacol. 115, 1265-1275
    • (1995) Br. J. Pharmacol. , vol.115 , pp. 1265-1275
    • Safieh-Garabedian, B.1
  • 37
    • 0031028773 scopus 로고    scopus 로고
    • Tumor necrosis factor enhances the capsaicin sensitivity of rat sensory neurons
    • Nicol, G.D. et al. (1997) Tumor necrosis factor enhances the capsaicin sensitivity of rat sensory neurons. J. Neurosci. 17, 975-982
    • (1997) J. Neurosci. , vol.17 , pp. 975-982
    • Nicol, G.D.1
  • 38
    • 0032589741 scopus 로고    scopus 로고
    • Interleukin-1beta induces substance P release from primary afferent neurons through the cyclooxygenase-2 system
    • Inoue, A. et al. (1999) Interleukin-1beta induces substance P release from primary afferent neurons through the cyclooxygenase-2 system. J. Neurochem. 73, 2206-2213
    • (1999) J. Neurochem. , vol.73 , pp. 2206-2213
    • Inoue, A.1
  • 39
    • 0031981294 scopus 로고    scopus 로고
    • gp130 cytokines, leukemia inhibitory factor and interleukin-6, induce neuropeptide expression in intact adult rat sensory neurons in vivo: Time-course, specificity and comparison with sciatic nerve axotomy
    • Thompson, S.W. et al. (1998) gp130 cytokines, leukemia inhibitory factor and interleukin-6, induce neuropeptide expression in intact adult rat sensory neurons in vivo: time-course, specificity and comparison with sciatic nerve axotomy. Neuroscience 84, 1247-1255
    • (1998) Neuroscience , vol.84 , pp. 1247-1255
    • Thompson, S.W.1
  • 40
    • 0037112041 scopus 로고    scopus 로고
    • The role of spinal neuroimmune activation in morphine tolerance/hyperalgesia in neuropathic and sham-operated rats
    • Raghavendra, V. et al. (2002) The role of spinal neuroimmune activation in morphine tolerance/hyperalgesia in neuropathic and sham-operated rats. J. Neurosci. 22, 9980-9989
    • (2002) J. Neurosci. , vol.22 , pp. 9980-9989
    • Raghavendra, V.1
  • 41
    • 0025759321 scopus 로고
    • Serum levels of tumour necrosis factor-alpha and interleukin-1 beta during leprosy reactional states
    • Sarno, E.N. et al. (1991) Serum levels of tumour necrosis factor-alpha and interleukin-1 beta during leprosy reactional states. Clin. Exp. Immunol. 84, 103-108
    • (1991) Clin. Exp. Immunol. , vol.84 , pp. 103-108
    • Sarno, E.N.1
  • 42
    • 0026522665 scopus 로고
    • Tumor necrosis factor production in patients with leprosy
    • Barnes, P.F. et al. (1992) Tumor necrosis factor production in patients with leprosy. Infect. Immun. 60, 1441-1446
    • (1992) Infect. Immun. , vol.60 , pp. 1441-1446
    • Barnes, P.F.1
  • 43
    • 0035933188 scopus 로고    scopus 로고
    • TNF-alpha expression in painful and nonpainful neuropathies
    • Empl, M. et al. (2001) TNF-alpha expression in painful and nonpainful neuropathies. Neurology 56, 1371-1377
    • (2001) Neurology , vol.56 , pp. 1371-1377
    • Empl, M.1
  • 44
    • 0038819417 scopus 로고    scopus 로고
    • Cytokines in sural nerve biopsies from inflammatory and non-inflammatory neuropathies
    • Lindenlaub, T. and Sommer, C. (2003) Cytokines in sural nerve biopsies from inflammatory and non-inflammatory neuropathies. Acta Neuropathol. 105, 593-602
    • (2003) Acta Neuropathol. , vol.105 , pp. 593-602
    • Lindenlaub, T.1    Sommer, C.2
  • 45
    • 10744225509 scopus 로고    scopus 로고
    • Cerebrospinal fluid interleukin 8 concentrations and the subsequent development of postherpetic neuralgia
    • Kotani, N. et al. (2004) Cerebrospinal fluid interleukin 8 concentrations and the subsequent development of postherpetic neuralgia. Am. J. Med. 116, 318-324
    • (2004) Am. J. Med. , vol.116 , pp. 318-324
    • Kotani, N.1
  • 46
    • 0036175334 scopus 로고    scopus 로고
    • Proinflammatory cytokines in cerebrospinal fluid and serum in patients with disc herniation and sciatica
    • Brisby, H. et al. (2002) Proinflammatory cytokines in cerebrospinal fluid and serum in patients with disc herniation and sciatica. Eur. Spine J. 11, 62-66
    • (2002) Eur. Spine J. , vol.11 , pp. 62-66
    • Brisby, H.1
  • 47
    • 0036201899 scopus 로고    scopus 로고
    • Intervertebral discs which cause low back pain secrete high levels of proinflammatory mediators
    • Burke, J.G. et al. (2002) Intervertebral discs which cause low back pain secrete high levels of proinflammatory mediators. J. Bone Joint Surg. Br. 84, 196-201
    • (2002) J. Bone Joint Surg. Br. , vol.84 , pp. 196-201
    • Burke, J.G.1
  • 48
    • 0036571243 scopus 로고    scopus 로고
    • mRNA expression of cytokines and chemokines in herniated lumbar intervertebral discs
    • Ahn, S.H. et al. (2002) mRNA expression of cytokines and chemokines in herniated lumbar intervertebral discs. Spine 27, 911-917
    • (2002) Spine , vol.27 , pp. 911-917
    • Ahn, S.H.1
  • 49
    • 0038352253 scopus 로고    scopus 로고
    • Perispinal TNF-alpha inhibition for discogenic pain
    • Tobinick, E.L. and Britschgi-Davoodifar, S. (2003) Perispinal TNF-alpha inhibition for discogenic pain. Swiss Med. Wkly. 133, 170-177
    • (2003) Swiss Med. Wkly. , vol.133 , pp. 170-177
    • Tobinick, E.L.1    Britschgi-Davoodifar, S.2
  • 50
    • 6944221364 scopus 로고    scopus 로고
    • Treatment of chronic inflammatory demyelinating polyneuropathy
    • Van Doorn, P.A. and Ruts, L. (2004) Treatment of chronic inflammatory demyelinating polyneuropathy. Curr. Opin. Neurol. 17, 607-613
    • (2004) Curr. Opin. Neurol. , vol.17 , pp. 607-613
    • Van Doorn, P.A.1    Ruts, L.2
  • 51
    • 0038674652 scopus 로고    scopus 로고
    • Successful treatment with low-dose thalidomide in a patinet with both Behcet's disease in complex regional pain syndrome type I
    • Ching, D.W.T. et al. (2003) Successful treatment with low-dose thalidomide in a patinet with both Behcet's disease in complex regional pain syndrome type I. J. Clin. Rheumatol. 9, 96-98
    • (2003) J. Clin. Rheumatol. , vol.9 , pp. 96-98
    • Ching, D.W.T.1
  • 52
    • 0033062162 scopus 로고    scopus 로고
    • Thalidomide as a blocker of TNF production
    • Sommer, C. (1999) Thalidomide as a blocker of TNF production. Drugs Future 24, 67-75
    • (1999) Drugs Future , vol.24 , pp. 67-75
    • Sommer, C.1
  • 53
    • 0037007683 scopus 로고    scopus 로고
    • Treatment of ankylosing spondylitis by inhibition of tumor necrosis factor alpha
    • Gorman, J.D. et al. (2002) Treatment of ankylosing spondylitis by inhibition of tumor necrosis factor alpha. N. Engl. J. Med. 346, 1349-1356
    • (2002) N. Engl. J. Med. , vol.346 , pp. 1349-1356
    • Gorman, J.D.1
  • 54
    • 12444336486 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha monoclonal anti-body, infliximab, used to manage severe sciatica
    • discussion 753-754
    • Karppinen, J. et al. (2003) Tumor necrosis factor-alpha monoclonal anti-body, infliximab, used to manage severe sciatica. Spine 28, 750-753 (discussion 753-754)
    • (2003) Spine , vol.28 , pp. 750-753
    • Karppinen, J.1
  • 55
    • 0013511183 scopus 로고    scopus 로고
    • Treatment of rheumatoid arthritis with a recombinant human tumor necrosis factor receptor (p75)-Fc fusion protein
    • Moreland, L.W. et al. (1997) Treatment of rheumatoid arthritis with a recombinant human tumor necrosis factor receptor (p75)-Fc fusion protein. N. Engl. J. Med. 337, 141-147
    • (1997) N. Engl. J. Med. , vol.337 , pp. 141-147
    • Moreland, L.W.1
  • 56
    • 0033524159 scopus 로고    scopus 로고
    • Infliximab (chimeric anti-tumour necrosis factor alpha monoclonal antibody) versus placebo in rheumatoid arthritis patients receiving concomitant methotrexate: A randomised phase III trial
    • ATTRACT Study Group
    • Maini, R. et al. (1999) Infliximab (chimeric anti-tumour necrosis factor alpha monoclonal antibody) versus placebo in rheumatoid arthritis patients receiving concomitant methotrexate: a randomised phase III trial. ATTRACT Study Group. Lancet 354, 1932-1939
    • (1999) Lancet , vol.354 , pp. 1932-1939
    • Maini, R.1
  • 57
    • 0034735842 scopus 로고    scopus 로고
    • nfliximab and methotrexate in the treatment of rheumatoid arthritis. Anti-tumor necrosis factor trial in Rheumatoid ATTRACT Study Group
    • Lipsky, P.E. et al. (2000) nfliximab and methotrexate in the treatment of rheumatoid arthritis. Anti-tumor necrosis factor trial in Rheumatoid ATTRACT Study Group. N. Engl. J. Med. 22, 1594-1602
    • (2000) N. Engl. J. Med. , vol.22 , pp. 1594-1602
    • Lipsky, P.E.1
  • 58
    • 0037231533 scopus 로고    scopus 로고
    • Adalimumab, a fully human anti-tumor necrosis factor alpha monoclonal antibody, for the treatment of rheumatoid arthritis in patients taking concomitant methotrexate: The ARMADA trial
    • Weinblatt, M.E. et al. (2003) Adalimumab, a fully human anti-tumor necrosis factor alpha monoclonal antibody, for the treatment of rheumatoid arthritis in patients taking concomitant methotrexate: the ARMADA trial. Arthritis Rheum. 48, 35-45
    • (2003) Arthritis Rheum. , vol.48 , pp. 35-45
    • Weinblatt, M.E.1
  • 59
    • 3242716045 scopus 로고    scopus 로고
    • Efficacy of etanercept in the treatment of acute and severe sciatica. A pilot study
    • Genevay, S. et al. (2004) Efficacy of etanercept in the treatment of acute and severe sciatica. A pilot study. Ann. Rheum. Dis. 63, 1120-1123
    • (2004) Ann. Rheum. Dis. , vol.63 , pp. 1120-1123
    • Genevay, S.1
  • 60
    • 3442878494 scopus 로고    scopus 로고
    • Anakinra: An inhibitor of IL-1 for the treatment of rheumatoid arthritis
    • Fleischmann, R. et al. (2004) Anakinra: an inhibitor of IL-1 for the treatment of rheumatoid arthritis. Expert Opin. Biol. Ther. 4, 1333-1344
    • (2004) Expert Opin. Biol. Ther. , vol.4 , pp. 1333-1344
    • Fleischmann, R.1
  • 61
    • 1542644751 scopus 로고    scopus 로고
    • Gene therapy: Novel treatments for poly neuropathy and chronic pain
    • Mata, M. et al. (2004) Gene therapy: novel treatments for poly neuropathy and chronic pain. Curr. Neurol. Neurosci. Rep. 4, 1-2
    • (2004) Curr. Neurol. Neurosci. Rep. , vol.4 , pp. 1-2
    • Mata, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.