Chronic inflammatory pain leads to increased blood-brain barrier permeability and tight junction protein alterations

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 289, Issue 2 58-2, 2005, Pages

  Brooks, Tracy A ^a   Hawkins, Brian T ^a   Huber, Jason D ^b   Egleton, Richard D ^a   Davis, Thomas P ^a  

^a UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

^b WEST VIRGINIA UNIVERSITY   (United States)

Author keywords

Central nervous system; Claudin; Complete Freund's adjuvant; Diffusion; Homeostasis; Membrane permeability; Occludin

Indexed keywords

ACTIN; CARBON 14; CELL MEMBRANE PROTEIN; CLAUDIN; CLAUDIN 3; CLAUDIN 5; FREUND ADJUVANT; OCCLUDIN; PROTEIN ZO1; SUCROSE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN EDEMA; CAPILLARY PERMEABILITY; CHRONIC INFLAMMATION; CHRONIC PAIN; CONTROLLED STUDY; ENDOTHELIUM CELL; FEMALE; HOMEOSTASIS; HYPERALGESIA; ISOTOPE LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; TIGHT JUNCTION; WESTERN BLOTTING;

ANIMALS; BLOOD PRESSURE; BLOOD-BRAIN BARRIER; CAPILLARY PERMEABILITY; CHRONIC DISEASE; EDEMA; FEMALE; FOOT; FREUND'S ADJUVANT; HYPERALGESIA; INFLAMMATION; INJECTIONS; MEMBRANE PROTEINS; PAIN; PERFUSION; RATS; RATS, SPRAGUE-DAWLEY; TIGHT JUNCTIONS; TISSUE DISTRIBUTION;

EID: 23744445782     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.01288.2004     Document Type: Article

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