Combination of chemotherapy without platinum compounds in the treatment of advanced non-small cell lung cancer: A systematic review of phase III trials

Lung Cancer

Volumn 49, Issue 3, 2005, Pages 289-298

  Barlési, Fabrice ^a,b   Pujol, Jean Louis ^a  

^a HÔPITAL ARNAUD DE VILLENEUVE   (France)

^b AIX MARSEILLE UNIVERSITY   (France)

Author keywords

Chemotherapy; Docetaxel; Gemcitabine; Non small cell lung cancer; Paclitaxel; Platinum free; Vinorelbine

Indexed keywords

ANTINEOPLASTIC AGENT; CARBOPLATIN; CISPLATIN; DOCETAXEL; EPIRUBICIN; GEMCITABINE; GRANULOCYTE COLONY STIMULATING FACTOR; IFOSFAMIDE; NAVELBINE; PACLITAXEL; PEMETREXED; PLATINUM DERIVATIVE; TAXANE DERIVATIVE;

BLOOD TOXICITY; BONE MARROW SUPPRESSION; CANCER COMBINATION CHEMOTHERAPY; CANCER SURVIVAL; CLINICAL TRIAL; DRUG EFFICACY; DRUG FATALITY; DRUG HYPERSENSITIVITY; DRUG SAFETY; EDEMA; FEBRILE NEUTROPENIA; FLUID RETENTION; HUMAN; INTERSTITIAL PNEUMONIA; LEUKOPENIA; LUNG NON SMALL CELL CANCER; NAUSEA AND VOMITING; NEUTROPENIA; OTOTOXICITY; PRIORITY JOURNAL; QUALITY OF LIFE; REVIEW; SIDE EFFECT; SURVIVAL RATE; SURVIVAL TIME; SYSTEMATIC REVIEW; TREATMENT OUTCOME;

ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CARCINOMA, NON-SMALL-CELL LUNG; CLINICAL TRIALS; CLINICAL TRIALS, PHASE III; DATABASES, BIBLIOGRAPHIC; DEOXYCYTIDINE; HUMANS; LUNG NEOPLASMS; PACLITAXEL; PLATINUM COMPOUNDS; QUALITY CONTROL; RANDOMIZED CONTROLLED TRIALS; TAXOIDS; TREATMENT OUTCOME; VINBLASTINE;

EID: 23744437871     PISSN: 01695002     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lungcan.2005.03.034     Document Type: Review

References (37)

1. E. Rapp, J.L. Pater, A. Willan, Y. Cormier, N. Murray, and W.K. Evans Chemotherapy can prolong survival in patients with advanced non-small cell lung cancer - report of a Canadian multi-center randomized trial J Clin Oncol 6 1998 633 641
2. Non-Small Cell Lung Cancer Collaborative Group Chemotherapy in non-small cell lung cancer: a meta-analysis using updated data on individual patients from 52 randomized clinical trials Br Med J 311 1995 899 909
3. P.J. Souquet, F. Chauvin, J.P. Boissel, R. Cellerino, Y. Cormier, and P.A. Ganz Polychemotherapy in advanced non-small cell lung cancer: a meta-analysis Lancet 342 1993 19 21
4. K. Hotta, K. Matsuo, H. Ueoka, K. Kiura, M. Tabata, and M. Tanimoto Meta-analysis of randomized clinical trials comparing cisplatin to carboplatin in patients with advanced non-small cell lung cancer J Clin Oncol 22 2004 3852 3859
5. R. Abratt, W. Bezwoda, G. Falkson, L. Goedhals, D. Hacking, and T. Rugg Drug efficacy and safety profile of gemcitabine in non-small cell lung cancer: a phase II study J Clin Oncol 12 1994 1535 1540
6. H. Anderson, P. Hopwood, R.J. Stephens, N. Thatcher, B. Cottier, and M. Nicholson Gemcitabine plus best supportive care (BSC) vs. BSC in inoperable non-small cell lung cancer - a randomized trial with quality of life as the primary outcome. UK NSCLC Gemcitabine Group Non-Small Cell Lung Cancer Br J Cancer 83 2000 447 453
7. M. Ranson, N. Davidson, M. Nicolson, S. Falk, J. Carmichael, and P. Lopez Randomized trial of paclitaxel plus supportive care versus supportive care for patients with advanced non-small-cell lung cancer J Natl Cancer Inst 92 2000 074 080
8. T. Cerny, S. Kaplan, N. Pavlidis, P. Schoffski, R. Epelbaum, and J. van Meerbeck Docetaxel (taxotere) is active in non-small cell lung cancer: a phase II trial of the EORTC-Clinical Trials Group Br J Cancer 70 1994 384 387
9. K. Roszkowski, A. Pluzanska, M. Krzakowski, A.P. Smith, E. Saigi, and U. Aasebo A multicenter, randomized, phase III study of docetaxel plus best supportive care versus best supportive care in chemotherapy-naive patients with metastatic or non-resectable localized non-small cell lung cancer (NSCLC) Lung Cancer 27 2000 145 157
10. F. Shepherd, J. Dancey, R. Ramlau, K. Mattson, R. Gralla, and M. O'Rourke Prospective randomized trial of docetaxel versus best supportive care in patients with non-small cell lung cancer previously treated with platinum-based chemotherapy J Clin Oncol 18 2000 2095 2103
11. The Elderly Lung Cancer Vinorelbine Italian Study group Effect of vinorelbine on quality of life and survival of elderly patients with advanced non-small cell lung cancer J Natl Cancer Inst 91 1999 66 72
12. K. Hotta, K. Matsuo, H. Ueoka, K. Kiura, M. Tabata, and M. Tanimoto Addition of platinum compounds to a new agent in patients with advanced non-small-cell lung cancer: a literature based meta-analysis of randomised trials Ann Oncol 15 2004 1782 1789
13. J.L. Pujol, X. Quantin, D. Choma, W. Jacot, and F. Khial Combination chemotherapy without cisplatin in the treatment of advanced non-small cell lung cancer Lung Cancer 38 2002 S57 S60
14. R.C. Lilenbaum, C.S. Chen, T. Chidiac, P.O. Schwarzenberger, M. Thant, and M. Versola Phase II randomized trial of vinorelbine and gemcitabine versus carboplatin and paclitaxel in advanced non-small-cell lung cancer Ann Oncol 16 2005 97 101
15. Y.M. Chen, R.P. Perng, Y.C. Lee, J.F. Shih, C.S. Lee, and C.M. Tsai Paclitaxel plus carboplatin, compared with paclitaxel plus gemcitabine, shows similar efficacy while more cost-effective: a randomized phase II study of combination chemotherapy against inoperable non-small-cell lung cancer previously untreated Ann Oncol 13 2002 108 115
16. L. Zhang, Y. Zhang, N. Li, F. Xu, Z.K. Pan, and Z.Z. Guan Gemcitabine plus cisplatin versus gemcitabine plus vinorelbine in treatment of advanced non-small cell lung cancer (NSCLC) Ai Zheng 23 2004 1455 1458
17. G. Frasci, V. Lorusso, N. Panza, P. Comella, G. Nicolella, and A. Bianco Gemcitabine plus vinorelbine versus vinorelbine alone in elderly patients with advanced non-small-cell lung cancer J Clin Oncol 18 2000 2529 2536
18. C. Gridelli, F. Perrone, C. Gallo, S. Cigolari, A. Rossi, F. Piantedosi MILES Investigators Chemotherapy for elderly patients with advanced non-small-cell lung cancer: the Multicenter Italian Lung Cancer in the Elderly Study (MILES) phase III randomized trial J Natl Cancer Inst 95 2003 341 343
19. V. Alberola, C. Camps, M. Provencio, D. Isla, R. Rosell, C. Vadell Spanish Lung Cancer Group Cisplatin plus gemcitabine versus a cisplatin-based triplet versus non-platinum sequential doublets in advanced non-small-cell lung cancer: a Spanish Lung Cancer Group phase III randomized trial J Clin Oncol 21 2003 3207 3213
20. E. Laack, N. Dickgreber, T. Muller, A. Knuth, J. Benk, C. Lorenz German and Swiss Lung Cancer Study Group Randomized phase III study of gemcitabine and vinorelbine versus gemcitabine, vinorelbine, and cisplatin in the treatment of advanced non-small-cell lung cancer: from the german and Swiss lung cancer study group J Clin Oncol 22 2004 2348 2356
21. C. Gridelli, C. Gallo, F.A. Shepherd, A. Illiano, F. Piantedosi, and S.F. Robbiati Gemcitabine plus vinorelbine compared with cisplatin plus vinorelbine or cisplatin plus gemcitabine for advanced non-small-cell lung cancer: a phase III Trial of the Italian GEMVIN Investigators and the National Cancer Institute of Canada Clinical Trials Group J Clin Oncol 21 2003 3025 3034
22. R. Abratt, A. Szczesna, K. Mattson, M. Wernli, P. Reiterer, and R. Hui Vinorelbine-carboplatin vs. non-platinum doublets in inoperable non-small cell lung cancer patients - final results of the Glob2 phase III with patient benefit analysis J Clin Oncol 14S 2004 A7016
23. M. Dunsford, G.M. Mead, A. Bateman, T. Cook, and K. Tung Severe pulmonary toxicity in patients treated with a combination of docetaxel and gemcitabine for metastatic transitional cell carcinoma Ann Oncol 10 1999 943 947
24. P. Kosmidis, N. Mylonakis, C. Nicolaides, C. Kalophonos, E. Samantas, and J. Boukovinas Paclitaxel plus carboplatin versus gemcitabine plus paclitaxel in advanced non-small-cell lung cancer: a phase III randomized trial J Clin Oncol 20 2002 3578 3585
25. E.F. Smit, J.P. van Meerbeeck, P. Lianes, C. Debruyne, C. Legrand, F. Schramel EORTC Lung Cancer Group Three-arm randomized study of two cisplatin-based regimens and paclitaxel plus gemcitabine in advanced non-small-cell lung cancer: a phase III trial of the European Organization for Research and Treatment of Cancer Lung Cancer Group - EORTC 08975 J Clin Oncol 21 2003 3909 3917
26. J. Treat, C. Belani, M. Edelman, M. Socinski, R. Gonin, and C. Obasaju A randomized phase III trial of gemcitabine in combination with carboplatin or paclitaxel versus paclitaxel plus carboplatin in advanced (stage IIIB IV) non-small cell lung cancer Proc Am Soc Clin Oncol 21 2003 A2511
27. V. Georgoulias, C. Kouroussis, N. Androulakis, S. Kakolyris, M.A. Dimopoulos, and E. Papadakis Front-line treatment of advanced non-small-cell lung cancer with docetaxel and gemcitabine: a multicenter phase II trial J Clin Oncol 17 1999 914 920
28. P. Rebattu, X. Quantin, C. Ardiet, J.F. Morere, M.R. Azarian, and M.P. Schuller-Lebeau Dose-finding, pharmacokinetic and phase II study of docetaxel in combination with gemcitabine in patients with inoperable non-small cell lung cancer Lung Cancer 33 2001 277 287
29. V. Georgoulias, E. Papadakis, A. Alexopoulos, X. Tsiafaki, A. Rapti, M. Veslemes Greek Oncology Cooperative Group (GOCG) for Lung Cancer Platinum-based and non-platinum-based chemotherapy in advanced non-small-cell lung cancer: a randomized multicentre trial Lancet 357 2001 1478
30. S. Kakolyris, X. Tsiafaki, A. Agelidou, J. Arapis, J. Boukovinas, N. Samaras The Greek Cooperative Group for Lung Cancer Preliminary results of a multicenter randomized phase III trial of docetaxel plus gemcitabine versus vinorelbine plus cisplatine in patients with advanced non-small cell lung cancer Proc Am Soc Clin Oncol 20 2002 A1182
31. J. Rigas, M. Carey, B. Cole, A. Evans, R. Page, and F. Yunus Multicenter web-based phase III study to test the survival equivalence of non-platinum-based vs. platinum-based therapy for advanced non-small cell lung cancer: the Dartmouth NPB chemotherapy trial (D0112) J Clin Oncol S14 2004 A7071
32. J.L. Pujol, J.L. Breton, R. Gervais, P. Rebattu, A. Depierre, and J.F. Morère Gemcitabine/docetaxel versus cisplatin/vinorelbine in advanced or metastatic non-small cell lung cancer: a phase III study addressing the case for cisplatin Ann Oncol 2005 (in press)
33. F. Wachters, J. van Putten, H. Kramer, Z. Erjavec, P. Eppinga, and J. Strijbos First-line gemcitabine with gemcitabine or epirubicin in advanced non-small cell lung cancer: a phase III trial Br J Cancer 89 2003 192 199
34. J.P. Sculier, J.J. Lafitte, J. Lecomte, T. Berghmans, J. Thiriaux, M.C. Florin on behalf of the European Lung Cancer Working Party Ann Oncol 13 2002 874 882
35. G.P. Stathopoulos, M. Veslemes, N. Georgatou, D. Antoniou, P. Giamboudakis, and K. Katis Front-line paclitaxel-vinorelbine versus paclitaxel-carboplatin in patients with advanced non-small-cell lung cancer: a randomized phase III trial Ann Oncol 15 2004 1048 1055
36. D.G. Pfister, D.H. Johnson, C.G. Azzoli, W. Sause, T.J. Smith, S. Baker Jr American Society of Clinical Oncology American Society of Clinical Oncology treatment of unresectable non-small-cell lung cancer guideline: update J Clin Oncol 22 2004 330 353
37. R.D. Gelber, A. Goldhisrsh, and B.F. Cole Evaluation of effectiveness: Q-TWiST. The International Breast cancer study group Cancer Treat Rev 19 1993 73 84