-
2
-
-
0028292341
-
Phase II trial of gemcitabine (2′2′ difluorodeoxycytidine) in patients with adenocarcinoma of the pancreas
-
Casper ES, Green MR, Kelsen DP, et al. Phase II trial of gemcitabine (2′2′ difluorodeoxycytidine) in patients with adenocarcinoma of the pancreas. Invest New Drugs 1994; 10: 29-34
-
(1994)
Invest New Drugs
, vol.10
, pp. 29-34
-
-
Casper, E.S.1
Green, M.R.2
Kelsen, D.P.3
-
3
-
-
8244254377
-
Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: A randomized trial
-
Burris HA, Moore M, Andersen J, et al. Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial. J Clin Oncol 1997; 15: 2403-13
-
(1997)
J Clin Oncol
, vol.15
, pp. 2403-2413
-
-
Burris, H.A.1
Moore, M.2
Andersen, J.3
-
4
-
-
0035165047
-
Gemcitabine: Progress in the treatment of pancreatic cancer
-
Heinemann V. Gemcitabine: progress in the treatment of pancreatic cancer. Oncology 2001; 60: 8-18
-
(2001)
Oncology
, vol.60
, pp. 8-18
-
-
Heinemann, V.1
-
5
-
-
0032807118
-
Experimental drugs and drug combinations in pancreatic cancer
-
Kroep JR, Pinedo HM, van Groeningen CJ, et al. Experimental drugs and drug combinations in pancreatic cancer. Ann Oncol 1999; 10 Suppl. 4: S234-8
-
(1999)
Ann Oncol
, vol.10
, Issue.4 SUPPL.
-
-
Kroep, J.R.1
Pinedo, H.M.2
Van Groeningen, C.J.3
-
6
-
-
0032950347
-
Enzyme inhibition, polyglutamation, and the effect of LY231514 (MTA) on purine biosynthesis
-
Mendelsohn LG, Shih C, Chen VJ, et al. Enzyme inhibition, polyglutamation, and the effect of LY231514 (MTA) on purine biosynthesis. Semin Oncol 1999; 26 (2 Suppl. 6): 42-7
-
(1999)
Semin Oncol
, vol.26
, Issue.2 SUPPL. 6
, pp. 42-47
-
-
Mendelsohn, L.G.1
Shih, C.2
Chen, V.J.3
-
7
-
-
0030891198
-
LY231514 a pyrrolo [2,3-d] pyrimidine based antifolate that inhibits multiple folate requiring enzymes
-
Shih C, Chen VJ, Gossett LS, et al. LY231514 a pyrrolo [2,3-d] pyrimidine based antifolate that inhibits multiple folate requiring enzymes. Cancer Res 1997; 57: 1116-23
-
(1997)
Cancer Res
, vol.57
, pp. 1116-1123
-
-
Shih, C.1
Chen, V.J.2
Gossett, L.S.3
-
8
-
-
0032990562
-
Activity of the multitargeted antifolate LY231514 in the human tumor-cloning assay
-
Britten CD, Izbicka E, Hilsenbeck S, et al. Activity of the multitargeted antifolate LY231514 in the human tumor-cloning assay. Cancer Chemother Pharmacol 1999; 44 (2): 105-10
-
(1999)
Cancer Chemother Pharmacol
, vol.44
, Issue.2
, pp. 105-110
-
-
Britten, C.D.1
Izbicka, E.2
Hilsenbeck, S.3
-
9
-
-
0032859301
-
A phase I evaluation of multitargeted antifolate (MTA, LY231514) administered every 21 days, utilizing the modified continual reassessment method for dose escalation
-
Rinaldi DA, Kuhn JG, Burris HA, et al. A phase I evaluation of multitargeted antifolate (MTA, LY231514) administered every 21 days, utilizing the modified continual reassessment method for dose escalation. Cancer Chemother Pharmacol 1999; 44: 372-80
-
(1999)
Cancer Chemother Pharmacol
, vol.44
, pp. 372-380
-
-
Rinaldi, D.A.1
Kuhn, J.G.2
Burris, H.A.3
-
10
-
-
0033981350
-
Phase II study of the multitargeted antifolate LY231514 (Alimta, MTA, pemetrexed disodium) in patients with advanced pancreatic cancer
-
Miller KD, Picus J, Blanke C, et al. Phase II study of the multitargeted antifolate LY231514 (Alimta, MTA, pemetrexed disodium) in patients with advanced pancreatic cancer. Ann Oncol 2000; 11: 101-3
-
(2000)
Ann Oncol
, vol.11
, pp. 101-103
-
-
Miller, K.D.1
Picus, J.2
Blanke, C.3
-
11
-
-
4243732564
-
Sequence dependence using combinations of ALIMTA (pemetrexed disodium, LY231514, MTA), gemcitabine and oxaliplatin in human colorectal carcinoma cell lines
-
abstract no. 503
-
Schultz R, Rothenberg M, Koury M, et al. Sequence dependence using combinations of ALIMTA (pemetrexed disodium, LY231514, MTA), gemcitabine and oxaliplatin in human colorectal carcinoma cell lines [abstract no. 503]. Clin Cancer Res 2000; 6: 4567S
-
(2000)
Clin Cancer Res
, vol.6
-
-
Schultz, R.1
Rothenberg, M.2
Koury, M.3
-
12
-
-
0033993714
-
Phase I and pharmacologic study of sequences of gemcitabine and the multitargeted antifolate agent in patients with advanced solid tumors
-
Adjei AA, Erlichman C, Sloan JA, et al. Phase I and pharmacologic study of sequences of gemcitabine and the multitargeted antifolate agent in patients with advanced solid tumors. J Clin Oncol 2000; 18: 1748-57
-
(2000)
J Clin Oncol
, vol.18
, pp. 1748-1757
-
-
Adjei, A.A.1
Erlichman, C.2
Sloan, J.A.3
-
13
-
-
0033179374
-
Cell cycle modulation by a multitargeted antifolate, LY231514, increases the cytotoxicity and antitumor activity of gemcitabine in HT29 colon carcinoma
-
Tonkinson JL, Worzalla JF, Teng CH, et al. Cell cycle modulation by a multitargeted antifolate, LY231514, increases the cytotoxicity and antitumor activity of gemcitabine in HT29 colon carcinoma. Cancer Res 1999; 59: 3671-6
-
(1999)
Cancer Res
, vol.59
, pp. 3671-3676
-
-
Tonkinson, J.L.1
Worzalla, J.F.2
Teng, C.H.3
-
14
-
-
0036155290
-
In vitro schedule-dependent interactions between the multitargeted antifolate LY231514 and Gemcitabine in human colon adenocarcinoma cell lines
-
Tesei A, Ricotti L, de Paola F, et al. In vitro schedule-dependent interactions between the multitargeted antifolate LY231514 and Gemcitabine in human colon adenocarcinoma cell lines. Clin Cancer Res 2002; 8: 233-9
-
(2002)
Clin Cancer Res
, vol.8
, pp. 233-239
-
-
Tesei, A.1
Ricotti, L.2
De Paola, F.3
-
15
-
-
4143063182
-
Dosage adjustment in renal disease
-
Shargel L, Yu ABC, editors. Norwalk (CT): Appleton-Century-Crofts
-
Shargel L, Yu ABC. Dosage adjustment in renal disease. In: Shargel L, Yu ABC, editors. Applied biopharmaceutics and pharmacokinetics. 2nd ed. Norwalk (CT): Appleton-Century-Crofts, 1985: 305-330
-
(1985)
Applied Biopharmaceutics and Pharmacokinetics. 2nd Ed.
, pp. 305-330
-
-
Shargel, L.1
Yu, A.B.C.2
-
16
-
-
0023271255
-
The Memorial Pain Assessment Card: A valid instrument for the evaluation of cancer pain
-
Fishman B, Pasternak S, Wallenstein SL, et al. The Memorial Pain Assessment Card: a valid instrument for the evaluation of cancer pain. Cancer 1987; 60: 1151-8
-
(1987)
Cancer
, vol.60
, pp. 1151-1158
-
-
Fishman, B.1
Pasternak, S.2
Wallenstein, S.L.3
-
17
-
-
0036562507
-
Homocysteine and methylmalonic acid: Markers to predict and avoid toxicity from pemetrexed therapy
-
Niyikiza C, Baker SD, Seitz DE, et al. Homocysteine and methylmalonic acid: markers to predict and avoid toxicity from pemetrexed therapy. Mol Cancer Ther 2002; 1: 545-52
-
(2002)
Mol Cancer Ther
, vol.1
, pp. 545-552
-
-
Niyikiza, C.1
Baker, S.D.2
Seitz, D.E.3
-
18
-
-
0027076295
-
Southwest Oncology Group standard response criteria, endpoint definitions, and toxicity criteria
-
Green S, Weiss GR. Southwest Oncology Group standard response criteria, endpoint definitions, and toxicity criteria. Invest New Drugs 1992; 10: 239-53
-
(1992)
Invest New Drugs
, vol.10
, pp. 239-253
-
-
Green, S.1
Weiss, G.R.2
-
19
-
-
0020108590
-
One-sample multiple testing procedure for phase 2 clinical trials
-
Fleming TR. One-sample multiple testing procedure for phase 2 clinical trials. Biometrics 1982; 38: 143-51
-
(1982)
Biometrics
, vol.38
, pp. 143-151
-
-
Fleming, T.R.1
-
20
-
-
33845382806
-
Nonparametric estimation of incomplete observations
-
Kaplan EL, Meier P. Nonparametric estimation of incomplete observations. JASA 1958; 53: 457-81
-
(1958)
JASA
, vol.53
, pp. 457-481
-
-
Kaplan, E.L.1
Meier, P.2
-
21
-
-
0033559213
-
An investigational new drug treatment program for patients with gemcitabine
-
Storniolo AM, Enas NH, Brown CA, et al. An investigational new drug treatment program for patients with gemcitabine. Cancer 1999; 85: 1261-8
-
(1999)
Cancer
, vol.85
, pp. 1261-1268
-
-
Storniolo, A.M.1
Enas, N.H.2
Brown, C.A.3
-
22
-
-
0031730802
-
Role of folic acid in modulating the toxicity and efficacy of the multitargeted antifolate, LY231514
-
Worzalla JF, Shih C, Schultz RM. Role of folic acid in modulating the toxicity and efficacy of the multitargeted antifolate, LY231514. Anticancer Res 1998; 18: 3235-9
-
(1998)
Anticancer Res
, vol.18
, pp. 3235-3239
-
-
Worzalla, J.F.1
Shih, C.2
Schultz, R.M.3
-
23
-
-
0041629528
-
Phase III study of pemetrexed in combination with cisplatin versus cisplatin alone in patients with malignant pleural mesothelioma
-
Vogelzang NJ, Rusthoven J, Symanowski JJ, et al. Phase III study of pemetrexed in combination with cisplatin versus cisplatin alone in patients with malignant pleural mesothelioma. J Clin Oncol 2003; 21 (14): 2636-44
-
(2003)
J Clin Oncol
, vol.21
, Issue.14
, pp. 2636-2644
-
-
Vogelzang, N.J.1
Rusthoven, J.2
Symanowski, J.J.3
-
24
-
-
0000025839
-
Randomized phase II trial of dose intense gemcitabine by standard infusion vs fixed dose rate in metastatic pancreatic adenocarcinoma
-
Tempero M, Plunkett W, Ruizvan Haperen V, et al. Randomized phase II trial of dose intense gemcitabine by standard infusion vs fixed dose rate in metastatic pancreatic adenocarcinoma [abstract]. Proc Am Soc Clin Oncol 1999; 18: 237a
-
(1999)
Proc Am Soc Clin Oncol
, vol.18
-
-
Tempero, M.1
Plunkett, W.2
Ruizvan Haperen, V.3
-
25
-
-
0036682041
-
Phase III study of gemcitabine in combination with fluorouracil versus gemcitabine alone in patients with advanced pancreatic carcinoma; Eastern Cooperative Oncology Group Trial E2297
-
Berlin JD, Catalano P, Thomas JP, et al. Phase III study of gemcitabine in combination with fluorouracil versus gemcitabine alone in patients with advanced pancreatic carcinoma; Eastern Cooperative Oncology Group Trial E2297. J Clin Oncol 2002; 20: 3270-5
-
(2002)
J Clin Oncol
, vol.20
, pp. 3270-3275
-
-
Berlin, J.D.1
Catalano, P.2
Thomas, J.P.3
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