메뉴 건너뛰기




Volumn 49, Issue 4, 1996, Pages 309-315

Biotransformation of caffeine by cDNA-expressed human cytochromes P-450

Author keywords

Biotransformation; Caffeine; CDNA expressed microsomes; CYP1A1; CYP1A2; CYP2D6 Met; CYP2D6 Val; CYP2E1

Indexed keywords

CAFFEINE; CYTOCHROME P450; PARAXANTHINE; THEOPHYLLINE;

EID: 0030057725     PISSN: 00316970     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF00226333     Document Type: Article
Times cited : (55)

References (26)
  • 1
    • 0023681409 scopus 로고
    • Caffeine and theophylline metabolism in newborn and adult human hepatocytes; comparison with adult rat hepatocytes
    • Berthou F, Ratanasavanh D, Alix D, Carlhant D, Riche C, Guillouzo A (1988) Caffeine and theophylline metabolism in newborn and adult human hepatocytes; comparison with adult rat hepatocytes. Biochem Pharmacol 37:3961-3700
    • (1988) Biochem Pharmacol , vol.37 , pp. 3961-13700
    • Berthou, F.1    Ratanasavanh, D.2    Alix, D.3    Carlhant, D.4    Riche, C.5    Guillouzo, A.6
  • 2
    • 0025848751 scopus 로고
    • Evidence for involvement of several cytochromes P-450 in the first steps of caffeine metabolism by human liver microsomes
    • Berthou F, Flinois JP, Ratanasavanh D, Beaune P, Riche C, Guillouzo A (1991) Evidence for involvement of several cytochromes P-450 in the first steps of caffeine metabolism by human liver microsomes. Drug Metab Dispos 3:561-567
    • (1991) Drug Metab Dispos , vol.3 , pp. 561-567
    • Berthou, F.1    Flinois, J.P.2    Ratanasavanh, D.3    Beaune, P.4    Riche, C.5    Guillouzo, A.6
  • 4
    • 0023113788 scopus 로고
    • Biotransformation of caffeine, paraxanthine, theophylline and theobromine by polycyclic aromatic hydrocarbone inducible cytochrome(s) P-450 in human liver microsomes
    • Campell ME, Grant DM, Inaba T, Kalow W (1987) Biotransformation of caffeine, paraxanthine, theophylline and theobromine by polycyclic aromatic hydrocarbone inducible cytochrome(s) P-450 in human liver microsomes. Drug Metab Dispos 2:237-249
    • (1987) Drug Metab Dispos , vol.2 , pp. 237-249
    • Campell, M.E.1    Grant, D.M.2    Inaba, T.3    Kalow, W.4
  • 7
    • 0027419948 scopus 로고
    • Cafeine, estradiol and progesterone interact with human CYP1A1 and 1A2. Evidence from cDNA-directed expression in Saccharomyces cerevisiae
    • Eugster HP, Probst M Wuergler FE, Sengstag C (1993) Cafeine, estradiol and progesterone interact with human CYP1A1 and 1A2. Evidence from cDNA-directed expression in Saccharomyces cerevisiae. Drug Metab Dispos 21:43-49
    • (1993) Drug Metab Dispos , vol.21 , pp. 43-49
    • Eugster, H.P.1    Probst, M.2    Wuergler, F.E.3    Sengstag, C.4
  • 8
    • 0026537062 scopus 로고
    • Biotransformation of caffeine and theophylline in mammalian cell lines genetically engineered for expression of single cytochrome P450 isoforms
    • Fuhr U, Doehmer J, Battula N, Woelfel C, Kudla C, Keita Y, Staib H (1992) Biotransformation of caffeine and theophylline in mammalian cell lines genetically engineered for expression of single cytochrome P450 isoforms. Biochem Pharmacol 43: 225-235
    • (1992) Biochem Pharmacol , vol.43 , pp. 225-235
    • Fuhr, U.1    Doehmer, J.2    Battula, N.3    Woelfel, C.4    Kudla, C.5    Keita, Y.6    Staib, H.7
  • 11
    • 0023273657 scopus 로고
    • Biotransformation of caffeine by microsomes from human liver. Kinetics and inhibition studies
    • Grant DM, Campell ME, Tang BK, Kalow W (1987) Biotransformation of caffeine by microsomes from human liver. Kinetics and inhibition studies. Biochem Pharmacol 36, 1251-1260
    • (1987) Biochem Pharmacol , vol.36 , pp. 1251-1260
    • Grant, D.M.1    Campell, M.E.2    Tang, B.K.3    Kalow, W.4
  • 12
    • 0026849441 scopus 로고
    • Biotransformation of caffeine, paraxanthine, theobromine and theophylline by cDNA-expressed CYP1A2 and CYP2E1
    • Gu L, Gonzalez FJ, Kalow W, Tang BK (1992) Biotransformation of caffeine, paraxanthine, theobromine and theophylline by cDNA-expressed CYP1A2 and CYP2E1. Pharmacogenetics 2: 73-77
    • (1992) Pharmacogenetics , vol.2 , pp. 73-77
    • Gu, L.1    Gonzalez, F.J.2    Kalow, W.3    Tang, B.K.4
  • 13
    • 0028929645 scopus 로고
    • Metabolism of theophylline by cDNA-expressed human cytochromes P-450
    • Ha HR, Chen J, Freiburghaus AU, Follath F (1995) Metabolism of theophylline by cDNA-expressed human cytochromes P-450. Br J Clin Pharmacol 39: 321-326
    • (1995) Br J Clin Pharmacol , vol.39 , pp. 321-326
    • Ha, H.R.1    Chen, J.2    Freiburghaus, A.U.3    Follath, F.4
  • 14
    • 0022656686 scopus 로고
    • Assessment of caffeine exposure: Caffeine content of beverages, caffeine intake, and plasma concentrations of methylxanthines
    • Lelo A, Miners JO, Robson R, Birkett DJ (1986) Assessment of caffeine exposure: caffeine content of beverages, caffeine intake, and plasma concentrations of methylxanthines. Clin Pharmacol Ther 39: 54-59
    • (1986) Clin Pharmacol Ther , vol.39 , pp. 54-59
    • Lelo, A.1    Miners, J.O.2    Robson, R.3    Birkett, D.J.4
  • 15
    • 0025790577 scopus 로고
    • Localization of CYP1A1 and CYP1A2 massenger RNA in normal human liver and in hepatocellular carcinoma by in situ hybridization
    • Mc Kinnon RA, De la M Hall P, Quattrochi LC, Tukey RH, McManus EC (1991) Localization of CYP1A1 and CYP1A2 massenger RNA in normal human liver and in hepatocellular carcinoma by in situ hybridization. Hepatology 14: 848-856
    • (1991) Hepatology , vol.14 , pp. 848-856
    • Mc Kinnon, R.A.1    De La M Hall, P.2    Quattrochi, L.C.3    Tukey, R.H.4    McManus, E.C.5
  • 17
    • 78651165715 scopus 로고
    • The carbon monoxide-binding pigment of liver microsomes. I. Evidence for its hemoprotein nature
    • Omura T, Sato R (1964) The carbon monoxide-binding pigment of liver microsomes. I. Evidence for its hemoprotein nature. J Biol Chem 239:2370-2378
    • (1964) J Biol Chem , vol.239 , pp. 2370-2378
    • Omura, T.1    Sato, R.2
  • 18
    • 0025951584 scopus 로고
    • Intralobular distribution and quantitation of cytochromes P-450 enzymes in human liver as a function of age
    • Ratanasavanh D, Beaune P, Morel F, Flinois JP, Guengerich FP, Guillouzo A (1991) Intralobular distribution and quantitation of cytochromes P-450 enzymes in human liver as a function of age. Hepatology 13:1142-1151
    • (1991) Hepatology , vol.13 , pp. 1142-1151
    • Ratanasavanh, D.1    Beaune, P.2    Morel, F.3    Flinois, J.P.4    Guengerich, F.P.5    Guillouzo, A.6
  • 19
    • 0027418624 scopus 로고
    • Caffeine as an analgesic adjuvant: A review of pharmacology and mechanisms of action
    • Sawynok J, Yaksh TL (1993) Caffeine as an analgesic adjuvant: a review of pharmacology and mechanisms of action. Pharmacol Rev 45:43-85
    • (1993) Pharmacol Rev , vol.45 , pp. 43-85
    • Sawynok, J.1    Yaksh, T.L.2
  • 20
    • 0027077438 scopus 로고
    • Characterization of lung microsomal cytochrome P450 1A1 and its role in the oxidation of chemical carcinogens
    • Shimada T, Yun CH, Yamazaki H, Gautier JC, Beaune PH, Guengerich FP (1992) Characterization of lung microsomal cytochrome P450 1A1 and its role in the oxidation of chemical carcinogens. Mol Pharmacol 41:856-864
    • (1992) Mol Pharmacol , vol.41 , pp. 856-864
    • Shimada, T.1    Yun, C.H.2    Yamazaki, H.3    Gautier, J.C.4    Beaune, P.H.5    Guengerich, F.P.6
  • 21
    • 0028237729 scopus 로고
    • Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: Studies with liver microsomes of 30 japaneses and 30 Caucasians
    • Shimada T, Yamazaki Y, Mimura M, Inui Y, Guengerich FP (1994) Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 japaneses and 30 Caucasians. J Pharmacol Exp Ther 270:414-423
    • (1994) J Pharmacol Exp Ther , vol.270 , pp. 414-423
    • Shimada, T.1    Yamazaki, Y.2    Mimura, M.3    Inui, Y.4    Guengerich, F.P.5
  • 22
    • 0017654380 scopus 로고
    • Simultanous assay of the methylxanthine metabolites of caffeine in plasma by high performance liquid chromatography
    • Sved S, Wilson DL (1977) Simultanous assay of the methylxanthine metabolites of caffeine in plasma by high performance liquid chromatography. Res Commun Pathol Pharmacol 17: 319-330
    • (1977) Res Commun Pathol Pharmacol , vol.17 , pp. 319-330
    • Sved, S.1    Wilson, D.L.2
  • 26
    • 0025344378 scopus 로고
    • Cytochrome P450 isoenzymes, epoxide hydrolase and glutathione transferases in rat and human hepatic and extrahepatic tissues
    • de Waziers I, Cugnenic PH, Yang CS, Leroux JP, Beaune PH (1990) Cytochrome P450 isoenzymes, epoxide hydrolase and glutathione transferases in rat and human hepatic and extrahepatic tissues. J Pharmacol Exp Ther 253:387-394
    • (1990) J Pharmacol Exp Ther , vol.253 , pp. 387-394
    • De Waziers, I.1    Cugnenic, P.H.2    Yang, C.S.3    Leroux, J.P.4    Beaune, P.H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.