2-(1-Hexyn-1-yl)adenosine-induced intraocular hypertension is mediated via K+ channel opening through adenosine A2A receptor in rabbits

European Journal of Pharmacology

Volumn 518, Issue 2-3, 2005, Pages 203-211

  Konno, Takashi ^a   Uchibori, Takehiro ^a   Nagai, Akihiko ^a   Kogi, Kentaro ^a   Nakahata, Norimichi ^b  

^a TOA EIYO LTD   (Japan)

^b TOHOKU UNIVERSITY   (Japan)

Author keywords

2 Alkynyladenosine derivative; Adenosine A2a receptor; Intraocular pressure; K+ channel; Outflow facility

Indexed keywords

2 (1 HEXYN 1 YL)ADENOSINE; 5 HYDROXYDECANOIC ACID; 8 (3 CHLOROSTYRYL)CAFFEINE; 8 CYCLOPENTYLTHEOPHYLLINE; ADENOSINE A1 RECEPTOR ANTAGONIST; ADENOSINE A2 RECEPTOR AGONIST; ADENOSINE A2 RECEPTOR ANTAGONIST; ADENOSINE A2A RECEPTOR; ADENOSINE A2B RECEPTOR ANTAGONIST; ADENOSINE DERIVATIVE; ADENOSINE TRIPHOSPHATE; GLIBENCLAMIDE; INDOMETACIN; POTASSIUM CHANNEL; POTASSIUM CHANNEL BLOCKING AGENT; PROSTAGLANDIN SYNTHASE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; INTRAOCULAR HYPERTENSION; INTRAOCULAR PRESSURE; MALE; NONHUMAN; PRIORITY JOURNAL; PROSTAGLANDIN RELEASE;

ADENOSINE; ALKYNES; ANIMALS; ANTIHYPERTENSIVE AGENTS; CAFFEINE; DECANOIC ACIDS; GLYBURIDE; HYDROXY ACIDS; HYPOTONIC SOLUTIONS; INTRAOCULAR PRESSURE; MALE; OCULAR HYPERTENSION; PHENETHYLAMINES; PINACIDIL; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS; RABBITS; RECEPTOR, ADENOSINE A2A; SODIUM CHLORIDE; TIME FACTORS; XANTHINES;

EID: 23644447403     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2005.03.002     Document Type: Article

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