Influence of acid surrogates toward potency of VLA-4 antagonist

Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 18, 2005, Pages 4053-4056

  Venkatraman, Shankar ^a   Lim, Jongwon ^a   Cramer, Merryl ^a   Gardner, Michael F ^a   James, Joyce ^a   Alves, Kenneth ^a   Lingham, Russell B ^a   Mumford, Richard A ^a   Munoz, Benito ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Acid surrogates; VLA 4 antagonist

Indexed keywords

BLOCKING AGENT; CARBOXYLIC ACID; HETEROCYCLIC COMPOUND; OXADIAZOLE DERIVATIVE; VERY LATE ACTIVATION ANTIGEN 4;

ARTICLE; BINDING ASSAY; DRUG HALF LIFE; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; NONHUMAN; RAT;

ACIDS; ANIMALS; INHIBITORY CONCENTRATION 50; INJECTIONS, INTRAVENOUS; INTEGRIN ALPHA4BETA1; MOLECULAR STRUCTURE; OXADIAZOLES; RATS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 23644434240     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.06.034     Document Type: Article

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