Solid-phase synthesis and anti-infective activity of a combinatorial library based on the natural product anisomycin

Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 18, 2005, Pages 4151-4154

  Shi, Shuhao ^a   Zhu, Shirong ^a   Gerritz, Samuel W ^a   Esposito, Kim ^b   Padmanabha, Ramesh ^b   Li, Wenying ^c   Herbst, John J ^c   Wong, Henry ^d   Yue, Zhong Shu ^c   Lam, Kin S ^c   Sofia, Michael J ^a  

^a New Leads Chemistry   (United States)

^b Lead Discovery   (United States)

^c Natural Products Chemistry   (United States)

^d BRISTOL MYERS SQUIBB   (United States)

Author keywords

Anisomycin library; Antibiotics; Candida albicans; Fungal; Solid phase synthesis; Staphylococcus aureus

Indexed keywords

ANISOMYCIN; NATURAL PRODUCT;

ANTIFUNGAL ACTIVITY; ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIUM; CELL ASSAY; COMBINATORIAL LIBRARY; EMBRYO; FUNGUS; HUMAN; HUMAN CELL; NONHUMAN; SOLID PHASE SYNTHESIS; STAPHYLOCOCCUS AUREUS; WHOLE CELL;

ANISOMYCIN; ANTI-INFECTIVE AGENTS; BIOLOGICAL PRODUCTS; CELL LINE; COMBINATORIAL CHEMISTRY TECHNIQUES; FUNGI; HUMANS; INHIBITORY CONCENTRATION 50; MOLECULAR STRUCTURE; STAPHYLOCOCCUS AUREUS; STRUCTURE-ACTIVITY RELATIONSHIP;

CANDIDA ALBICANS; STAPHYLOCOCCUS AUREUS;

EID: 23644434088     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.06.004     Document Type: Article

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