Clues for new therapeutics in osteoporosis

New England Journal of Medicine

Volumn 350, Issue 18, 2004, Pages 1902-1903

  Serhan, Charles N ^a  

^a HARVARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARACHIDONATE 12 LIPOXYGENASE; ARACHIDONATE 15 LIPOXYGENASE; ENZYME INHIBITOR; 12 15 LIPOXYGENASE; 12-15-LIPOXYGENASE;

ANIMAL MODEL; BONE DENSITY; BONE DEVELOPMENT; BONE MARROW CELL; BONE MASS; BONE MINERAL; CELL DIFFERENTIATION; CELL INTERACTION; CONTROLLED STUDY; GENE EXPRESSION; INBRED STRAIN; MOUSE; NONHUMAN; OSTEOBLAST; OSTEOPOROSIS; PRIORITY JOURNAL; SHORT SURVEY; ANIMAL; ARTICLE; DRUG ANTAGONISM; ENZYMOLOGY; FEMALE; GENETICS; HUMAN; METABOLISM; RABBIT;

ANIMALS; ARACHIDONATE 12-LIPOXYGENASE; ARACHIDONATE 15-LIPOXYGENASE; BONE DENSITY; FEMALE; HUMANS; MICE; OSTEOPOROSIS; RABBITS;

EID: 2342625293     PISSN: 00284793     EISSN: None     Source Type: Journal    
DOI: 10.1056/NEJMcibr040318     Document Type: Short Survey

References (5)

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2. Serhan CN, Jain A, Marleau S, et al. Reduced inflammation and tissue damage in transgenic rabbits overexpressing 15-lipoxygenase and endogenous anti-inflammatory lipid mediators. J Immunol 2003;171:6856-65.
3. Goh J, Godson C, Brady HR, Macmathuna P. Lipoxins: pro-resolution lipid mediators in intestinal inflammation. Gastroenterology 2003;124:1043-54.
4. Kobayashi T, Narumiya S. Function of prostanoid receptors: studies on knockout mice. Prostaglandins Other Lipid Mediat 2002;68-69:557-73.
5. Krieg P, Marks F, Fürstenberger G. A gene cluster encoding human epidermis-type lipoxygenases at chromosome 17p13.1: cloning, physical mapping, and expression. Genomics 2001;73:323-30.