A physiological pharmacokinetic model for solute disposition in tissues below a topical application site

Pharmaceutical Research

Volumn 16, Issue 9, 1999, Pages 1392-1398

  Roberts, Michael S ^a   Cross, Sheree E ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Binding; Cutaneous perfusion; Dermal absorption; Half life; Pharmacokinetics; Topical application

Indexed keywords

BOVINE SERUM ALBUMIN; DEXTRAN; DIAZEPAM; DICLOFENAC; LIDOCAINE; WATER;

ANIMAL TISSUE; ARTICLE; DRUG ABSORPTION; DRUG BINDING; DRUG DISPOSITION; DRUG HALF LIFE; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SKIN ABSORPTION; SKIN BLOOD FLOW;

ADMINISTRATION, TOPICAL; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; DEXTRANS; DICLOFENAC; HALF-LIFE; KINETICS; MALE; NONLINEAR DYNAMICS; PROTEIN BINDING; RATS; RATS, WISTAR; REGIONAL BLOOD FLOW; REGRESSION ANALYSIS; SERUM ALBUMIN, BOVINE; SKIN; SKIN ABSORPTION; SOLUTIONS;

EID: 0032835415     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1018998908655     Document Type: Article

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