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Volumn 16, Issue 1, 2004, Pages 246-253

The opioid agonist morphine decreases the dyskinetic response to dopaminergic agents in parkinsonian monkeys

Author keywords

Basal ganglia; Dopamine; Dyskinesias; Opioids; Parkinson

Indexed keywords

DOPAMINE RECEPTOR STIMULATING AGENT; LEVODOPA; MORPHINE; OPIATE AGONIST;

EID: 2342576336     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2004.02.002     Document Type: Article
Times cited : (37)

References (53)
  • 2
    • 0032798111 scopus 로고    scopus 로고
    • Reduction of dyskinesia and induction of akinesia induced by morphine in two parkinsonian patients with severe sciatica
    • Berg D., Becker G., Reiners K. Reduction of dyskinesia and induction of akinesia induced by morphine in two parkinsonian patients with severe sciatica. J. Neural Transm. 106:1999;725-728
    • (1999) J. Neural Transm. , vol.106 , pp. 725-728
    • Berg, D.1    Becker, G.2    Reiners, K.3
  • 3
    • 0035029246 scopus 로고    scopus 로고
    • Upregulation of striatal preproenkephalin gene expression occurs before the appearance of parkinsonian signs in 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine monkeys
    • Bezard E., Ravenscroft P., Gross C.E., Crossman A.R., Brotchie J.M. Upregulation of striatal preproenkephalin gene expression occurs before the appearance of parkinsonian signs in 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine monkeys. Neurobiol. Dis. 8:2001;343-350
    • (2001) Neurobiol. Dis. , vol.8 , pp. 343-350
    • Bezard, E.1    Ravenscroft, P.2    Gross, C.E.3    Crossman, A.R.4    Brotchie, J.M.5
  • 5
    • 0031739073 scopus 로고    scopus 로고
    • Adjuncts to dopamine replacement: A pragmatic approach to reducing the problem of dyskinesia in Parkinson's disease
    • Brotchie J.M. Adjuncts to dopamine replacement: a pragmatic approach to reducing the problem of dyskinesia in Parkinson's disease. Mov. Disord. 13:1998;871-876
    • (1998) Mov. Disord. , vol.13 , pp. 871-876
    • Brotchie, J.M.1
  • 6
    • 0031604255 scopus 로고    scopus 로고
    • Opioid peptide precursor expression in animal models of dystonia secondary to dopamine-replacement therapy in Parkinson's disease
    • Brotchie J.M., Henry B., Hille C.J., Crossman A.R. Opioid peptide precursor expression in animal models of dystonia secondary to dopamine-replacement therapy in Parkinson's disease. Adv. Neurol. 78:1998;41-52
    • (1998) Adv. Neurol. , vol.78 , pp. 41-52
    • Brotchie, J.M.1    Henry, B.2    Hille, C.J.3    Crossman, A.R.4
  • 7
    • 0036159502 scopus 로고    scopus 로고
    • Increase of preproenkephalin mRNA levels in the putamen of Parkinson disease patients with levodopa-induced dyskinesias
    • Calon F., Birdi S., Rajput A.H., Hornykiewicz O., Bédard P.J., Di Paolo T. Increase of preproenkephalin mRNA levels in the putamen of Parkinson disease patients with levodopa-induced dyskinesias. J. Neuropathol. Exp. Neurol. 61:2002;186-196
    • (2002) J. Neuropathol. Exp. Neurol. , vol.61 , pp. 186-196
    • Calon, F.1    Birdi, S.2    Rajput, A.H.3    Hornykiewicz, O.4    Bédard, P.J.5    Di Paolo, T.6
  • 8
    • 0028093394 scopus 로고
    • Prefrontal corticostriatal afferents maintain increased enkephalin gene expression in the dopamine-denervated rat striatum
    • Campbell K., Bjorklund A. Prefrontal corticostriatal afferents maintain increased enkephalin gene expression in the dopamine-denervated rat striatum. Eur. J. Neurosci. 6:1994;1371-1383
    • (1994) Eur. J. Neurosci. , vol.6 , pp. 1371-1383
    • Campbell, K.1    Bjorklund, A.2
  • 9
    • 0020036185 scopus 로고
    • Primary structure of the human Met- and Leu-enkephalin precursor and its mRNA
    • Comb M., Seeburg P.H., Adelman J., Eiden L., Herbert E. Primary structure of the human Met- and Leu-enkephalin precursor and its mRNA. Nature. 295:1982;663-666
    • (1982) Nature , vol.295 , pp. 663-666
    • Comb, M.1    Seeburg, P.H.2    Adelman, J.3    Eiden, L.4    Herbert, E.5
  • 11
    • 17344390118 scopus 로고    scopus 로고
    • Topographical organization of opioid peptide precursor gene expression following repeated apomorphine treatment in the 6-hydroxydopamine-lesioned rat
    • Duty S., Henry B., Crossman A.R., Brotchie J.M. Topographical organization of opioid peptide precursor gene expression following repeated apomorphine treatment in the 6-hydroxydopamine-lesioned rat. Exp. Neurol. 150:1998;223-234
    • (1998) Exp. Neurol. , vol.150 , pp. 223-234
    • Duty, S.1    Henry, B.2    Crossman, A.R.3    Brotchie, J.M.4
  • 12
    • 0032078541 scopus 로고    scopus 로고
    • Integrated events in central dopamine transmission as analyzed at multiple levels. Evidence for intramembrane adenosine A2A/dopamine D2 and adenosine A1/dopamine D1 receptor interactions in the basal ganglia
    • Fuxe K., Ferre S., Zoli M., Agnati L.F. Integrated events in central dopamine transmission as analyzed at multiple levels. Evidence for intramembrane adenosine A2A/dopamine D2 and adenosine A1/dopamine D1 receptor interactions in the basal ganglia. Brain Res. Brain Res. Rev. 26:1998;258-273
    • (1998) Brain Res. Brain Res. Rev. , vol.26 , pp. 258-273
    • Fuxe, K.1    Ferre, S.2    Zoli, M.3    Agnati, L.F.4
  • 13
    • 0025572196 scopus 로고
    • D1 and D2 dopamine receptor-regulated gene expression of striatonigral and striatopallidal neurons
    • Gerfen C.R., Engber T.M., Mahan L.C., Susel Z., Chase T.N., Monsma F.J. Jr., Sibley D.R. D1 and D2 dopamine receptor-regulated gene expression of striatonigral and striatopallidal neurons. Science. 250:1990;1429-1432
    • (1990) Science , vol.250 , pp. 1429-1432
    • Gerfen, C.R.1    Engber, T.M.2    Mahan, L.C.3    Susel, Z.4    Chase, T.N.5    Monsma Jr., F.J.6    Sibley, D.R.7
  • 14
    • 0025944714 scopus 로고
    • Dopamine differentially regulates dynorphin, substance P, and enkephalin expression in striatal neurons: In situ hybridization histochemical analysis
    • Gerfen C.R., McGinty J.F., Young W.S. III Dopamine differentially regulates dynorphin, substance P, and enkephalin expression in striatal neurons: in situ hybridization histochemical analysis. J. Neurosci. 11:1991;1016-1031
    • (1991) J. Neurosci. , vol.11 , pp. 1016-1031
    • Gerfen, C.R.1    McGinty, J.F.2    Young III, W.S.3
  • 15
    • 0035798093 scopus 로고    scopus 로고
    • The neurobiology of slow synaptic transmission
    • Greengard P. The neurobiology of slow synaptic transmission. Science. 294:2001;1024-1030
    • (2001) Science , vol.294 , pp. 1024-1030
    • Greengard, P.1
  • 16
    • 0035793308 scopus 로고    scopus 로고
    • Effects of acute and repeated treatment with a novel dopamine D2 receptor ligand on L-DOPA-induced dyskinesias in MPTP monkeys
    • Hadj Tahar A., Ekesbo A., Grégoire L., Bangassoro E., Svensson K.A., Tedroff J., Bédard P.J. Effects of acute and repeated treatment with a novel dopamine D2 receptor ligand on L-DOPA-induced dyskinesias in MPTP monkeys. Eur. J. Pharmacol. 412:2001;247-254
    • (2001) Eur. J. Pharmacol. , vol.412 , pp. 247-254
    • Hadj Tahar, A.1    Ekesbo, A.2    Grégoire, L.3    Bangassoro, E.4    Svensson, K.A.5    Tedroff, J.6    Bédard, P.J.7
  • 17
    • 0037208585 scopus 로고    scopus 로고
    • New insights in Parkinson's disease therapy: Can levodopa induced dyskinesia ever be manageable
    • A. Gordin, S. Kaakkola, & H. Teravainen. Philadelphia: Lippincott Williams and Wilkins
    • Hadj Tahar A., Grondin R., Grégoire L., Calon F., Di Paolo T., Bédard P.J. New insights in Parkinson's disease therapy: can levodopa induced dyskinesia ever be manageable. Gordin A., Kaakkola S., Teravainen H. Parkinsons' Disease: Advances in Neurology. 2003;51-64 Lippincott Williams and Wilkins, Philadelphia
    • (2003) Parkinsons' Disease: Advances in Neurology , pp. 51-64
    • Hadj Tahar, A.1    Grondin, R.2    Grégoire, L.3    Calon, F.4    Di Paolo, T.5    Bédard, P.J.6
  • 18
    • 0029923030 scopus 로고    scopus 로고
    • Chronic dizocilpine maleate (MK-801) treatment suppresses the effects of nigrostriatal dopamine deafferentation on enkephalin but not on substance P expression in the rat striatum
    • Hajji M.D., Salin P., Kerkerian-le Goff L. Chronic dizocilpine maleate (MK-801) treatment suppresses the effects of nigrostriatal dopamine deafferentation on enkephalin but not on substance P expression in the rat striatum. Eur. J. Neurosci. 8:1996;917-926
    • (1996) Eur. J. Neurosci. , vol.8 , pp. 917-926
    • Hajji, M.D.1    Salin, P.2    Kerkerian-Le Goff, L.3
  • 20
    • 0029762313 scopus 로고    scopus 로고
    • Potential of opioid antagonists in the treatment of levodopa-induced dyskinesias in Parkinson's disease
    • Henry B., Brotchie J.M. Potential of opioid antagonists in the treatment of levodopa-induced dyskinesias in Parkinson's disease. Drugs Aging. 9:1996;149-158
    • (1996) Drugs Aging , vol.9 , pp. 149-158
    • Henry, B.1    Brotchie, J.M.2
  • 21
    • 0034851915 scopus 로고    scopus 로고
    • Mu- and delta-opioid receptor antagonists reduce levodopa-induced dyskinesia in the MPTP-lesioned primate model of Parkinson's disease
    • Henry B., Fox S.H., Crossman A.R., Brotchie J.M. Mu- and delta-opioid receptor antagonists reduce levodopa-induced dyskinesia in the MPTP-lesioned primate model of Parkinson's disease. Exp. Neurol. 171:2001;139-146
    • (2001) Exp. Neurol. , vol.171 , pp. 139-146
    • Henry, B.1    Fox, S.H.2    Crossman, A.R.3    Brotchie, J.M.4
  • 22
    • 0026608174 scopus 로고
    • Pre- and postsynaptic inhibition by opioids in rat striatum
    • Jiang Z.G., North R.A. Pre- and postsynaptic inhibition by opioids in rat striatum. J. Neurosci. 12:1992;356-361
    • (1992) J. Neurosci. , vol.12 , pp. 356-361
    • Jiang, Z.G.1    North, R.A.2
  • 23
    • 0029417155 scopus 로고
    • Recent advances in molecular recognition and signal transduction of active peptides: Receptors for opioid peptides
    • Kieffer B.L. Recent advances in molecular recognition and signal transduction of active peptides: receptors for opioid peptides. Cell. Mol. Neurobiol. 15:1995;615-635
    • (1995) Cell. Mol. Neurobiol. , vol.15 , pp. 615-635
    • Kieffer, B.L.1
  • 25
    • 0033005506 scopus 로고    scopus 로고
    • Mu- and delta-opioid receptor agonists inhibit DARPP-32 phosphorylation in distinct populations of striatal projection neurons
    • Lindskog M., Svenningsson P., Fredholm B., Greengard P., Fisone G. Mu- and delta-opioid receptor agonists inhibit DARPP-32 phosphorylation in distinct populations of striatal projection neurons. Eur. J. Neurosci. 11:1999;2182-2186
    • (1999) Eur. J. Neurosci. , vol.11 , pp. 2182-2186
    • Lindskog, M.1    Svenningsson, P.2    Fredholm, B.3    Greengard, P.4    Fisone, G.5
  • 27
    • 0023390553 scopus 로고
    • Autoradiographic differentiation of mu, delta, and kappa opioid receptors in the rat forebrain and midbrain
    • Mansour A., Khachaturian H., Lewis M.E., Akil H., Watson S.J. Autoradiographic differentiation of mu, delta, and kappa opioid receptors in the rat forebrain and midbrain. J. Neurosci. 7:1987;2445-2464
    • (1987) J. Neurosci. , vol.7 , pp. 2445-2464
    • Mansour, A.1    Khachaturian, H.2    Lewis, M.E.3    Akil, H.4    Watson, S.J.5
  • 28
    • 0027988507 scopus 로고
    • Problems with long-term levodopa therapy for Parkinson's disease
    • Marsden C.D. Problems with long-term levodopa therapy for Parkinson's disease. Clin. Neuropharmacol. 17(Suppl. 2):1994;S32-S44
    • (1994) Clin. Neuropharmacol. , vol.17 , Issue.SUPPL. 2 , pp. 32-S44
    • Marsden, C.D.1
  • 29
    • 0037723832 scopus 로고    scopus 로고
    • Compensatory regulation of striatal neuropeptide gene expression occurs before changes in metabolic activity of basal ganglia nuclei
    • Meissner W., Dovero S., Bioulac B., Gross C.E., Bezard E. Compensatory regulation of striatal neuropeptide gene expression occurs before changes in metabolic activity of basal ganglia nuclei. Neurobiol. Dis. 13:2003;46-54
    • (2003) Neurobiol. Dis. , vol.13 , pp. 46-54
    • Meissner, W.1    Dovero, S.2    Bioulac, B.3    Gross, C.E.4    Bezard, E.5
  • 30
    • 0030722477 scopus 로고    scopus 로고
    • Preproenkephalin mRNA expression in the caudate-putamen of MPTP monkeys after chronic treatment with the D2 agonist U91356A in continuous or intermittent mode of administration: Comparison with L-DOPA therapy
    • Morissette M., Goulet M., Soghomonian J.J., Blanchet P.J., Calon F., Bédard P.J., Di Paolo T. Preproenkephalin mRNA expression in the caudate-putamen of MPTP monkeys after chronic treatment with the D2 agonist U91356A in continuous or intermittent mode of administration: comparison with L-DOPA therapy. Brain Res. Mol. Brain Res. 49:1997;55-62
    • (1997) Brain Res. Mol. Brain Res. , vol.49 , pp. 55-62
    • Morissette, M.1    Goulet, M.2    Soghomonian, J.J.3    Blanchet, P.J.4    Calon, F.5    Bédard, P.J.6    Di Paolo, T.7
  • 31
    • 0032902460 scopus 로고    scopus 로고
    • Differential regulation of striatal preproenkephalin and preprotachykinin mRNA levels in MPTP-lesioned monkeys chronically treated with dopamine D1 or D2 receptor agonists
    • Morissette M., Grondin R., Goulet M., Bédard P.J., Di Paolo T. Differential regulation of striatal preproenkephalin and preprotachykinin mRNA levels in MPTP-lesioned monkeys chronically treated with dopamine D1 or D2 receptor agonists. J. Neurochem. 72:1999;682-692
    • (1999) J. Neurochem. , vol.72 , pp. 682-692
    • Morissette, M.1    Grondin, R.2    Goulet, M.3    Bédard, P.J.4    Di Paolo, T.5
  • 32
    • 0034667715 scopus 로고    scopus 로고
    • A common signaling pathway for striatal NMDA and adenosine A2a receptors: Implications for the treatment of Parkinson's disease
    • Nash J.E., Brotchie J.M. A common signaling pathway for striatal NMDA and adenosine A2a receptors: implications for the treatment of Parkinson's disease. J. Neurosci. 20:2000;7782-7789
    • (2000) J. Neurosci. , vol.20 , pp. 7782-7789
    • Nash, J.E.1    Brotchie, J.M.2
  • 33
    • 0034109592 scopus 로고    scopus 로고
    • Pathophysiology of levodopa-induced dyskinesias in Parkinson's disease: Problems with the current model
    • Obeso J.A., Rodriguez-Oroz M.C., Rodriguez M., DeLong M.R., Olanow C.W. Pathophysiology of levodopa-induced dyskinesias in Parkinson's disease: problems with the current model. Ann. Neurol. 47:2000;S22-S32
    • (2000) Ann. Neurol. , vol.47 , pp. 22-S32
    • Obeso, J.A.1    Rodriguez-Oroz, M.C.2    Rodriguez, M.3    Delong, M.R.4    Olanow, C.W.5
  • 34
    • 0030792360 scopus 로고    scopus 로고
    • Protein kinase a inhibitor attenuates levodopa-induced motor response alterations in the hemi-parkinsonian rat
    • Oh J.D., Del Dotto P., Chase T.N. Protein kinase A inhibitor attenuates levodopa-induced motor response alterations in the hemi-parkinsonian rat. Neurosci. Lett. 228:1997;5-8
    • (1997) Neurosci. Lett. , vol.228 , pp. 5-8
    • Oh, J.D.1    Del Dotto, P.2    Chase, T.N.3
  • 35
  • 36
    • 0032889771 scopus 로고    scopus 로고
    • Expression of mu, kappa, and delta opioid receptor messenger RNA in the human CNS: A 33P in situ hybridization study
    • Peckys D., Landwehrmeyer G.B. Expression of mu, kappa, and delta opioid receptor messenger RNA in the human CNS: a 33P in situ hybridization study. Neuroscience. 88:1999;1093-1135
    • (1999) Neuroscience , vol.88 , pp. 1093-1135
    • Peckys, D.1    Landwehrmeyer, G.B.2
  • 38
    • 0034850112 scopus 로고    scopus 로고
    • Anatomy, physiology, and pharmacology of the basal ganglia
    • Pollack A.E. Anatomy, physiology, and pharmacology of the basal ganglia. Neurol. Clin. 19:2001;523-534
    • (2001) Neurol. Clin. , vol.19 , pp. 523-534
    • Pollack, A.E.1
  • 39
    • 0037008416 scopus 로고    scopus 로고
    • Increases in striatal preproenkephalin gene expression are associated with nigrostriatal damage but not L-DOPA-induced dyskinesias in the squirrel monkey
    • Quik M., Police S., Langston J.W., Di Monte D.A. Increases in striatal preproenkephalin gene expression are associated with nigrostriatal damage but not L-DOPA-induced dyskinesias in the squirrel monkey. Neuroscience. 113:2002;213-220
    • (2002) Neuroscience , vol.113 , pp. 213-220
    • Quik, M.1    Police, S.2    Langston, J.W.3    Di Monte, D.A.4
  • 41
    • 0142122419 scopus 로고    scopus 로고
    • Opioid antagonists increase the dyskinetic response to dopaminergic agents in parkinsonian monkeys: Interaction between dopamine and opioid systems
    • Samadi P., Grégoire L., Bédard P.J. Opioid antagonists increase the dyskinetic response to dopaminergic agents in parkinsonian monkeys: interaction between dopamine and opioid systems. Neuropharmacology. 45:2003;954-963
    • (2003) Neuropharmacology , vol.45 , pp. 954-963
    • Samadi, P.1    Grégoire, L.2    Bédard, P.J.3
  • 42
    • 0027339887 scopus 로고
    • Adenosine A2 receptors regulate the gene expression of striatopallidal and striatonigral neurons
    • Schiffmann S.N., Vanderhaeghen J.J. Adenosine A2 receptors regulate the gene expression of striatopallidal and striatonigral neurons. J. Neurosci. 13:1993;1080-1087
    • (1993) J. Neurosci. , vol.13 , pp. 1080-1087
    • Schiffmann, S.N.1    Vanderhaeghen, J.J.2
  • 43
    • 0033179592 scopus 로고    scopus 로고
    • Striatal preproenkephalin gene expression is upregulated in acute but not chronic parkinsonian monkeys: Implications for the contribution of the indirect striatopallidal circuit to parkinsonian symptomatology
    • Schneider J.S., Decamp E., Wade T. Striatal preproenkephalin gene expression is upregulated in acute but not chronic parkinsonian monkeys: implications for the contribution of the indirect striatopallidal circuit to parkinsonian symptomatology. J. Neurosci. 19:1999;6643-6649
    • (1999) J. Neurosci. , vol.19 , pp. 6643-6649
    • Schneider, J.S.1    Decamp, E.2    Wade, T.3
  • 44
    • 0034717725 scopus 로고    scopus 로고
    • Striatal enkephalin gene expression does not reflect parkinsonian signs
    • Schroeder J.A., Schneider J.S. Striatal enkephalin gene expression does not reflect parkinsonian signs. NeuroReport. 11:2000;1799-1802
    • (2000) NeuroReport , vol.11 , pp. 1799-1802
    • Schroeder, J.A.1    Schneider, J.S.2
  • 45
    • 0025371482 scopus 로고
    • The neural network of the basal ganglia as revealed by the study of synaptic connections of identified neurones
    • Smith A.D., Bolam J.P. The neural network of the basal ganglia as revealed by the study of synaptic connections of identified neurones. Trends Neurosci. 13:1990;259-265
    • (1990) Trends Neurosci. , vol.13 , pp. 259-265
    • Smith, A.D.1    Bolam, J.P.2
  • 46
    • 0028987683 scopus 로고
    • Glutamate/dopamine D1/D2 balance in the basal ganglia and its relevance to Parkinson's disease
    • Starr M.S. Glutamate/dopamine D1/D2 balance in the basal ganglia and its relevance to Parkinson's disease. Synapse. 19:1995;264-293
    • (1995) Synapse , vol.19 , pp. 264-293
    • Starr, M.S.1
  • 47
    • 0031594380 scopus 로고    scopus 로고
    • Activation of adenosine A2A and dopamine D1 receptors stimulates cyclic AMP-dependent phosphorylation of DARPP-32 in distinct populations of striatal projection neurons
    • Svenningsson P., Lindskog M., Rognoni F., Fredholm B.B., Greengard P., Fisone G. Activation of adenosine A2A and dopamine D1 receptors stimulates cyclic AMP-dependent phosphorylation of DARPP-32 in distinct populations of striatal projection neurons. Neuroscience. 84:1998;223-228
    • (1998) Neuroscience , vol.84 , pp. 223-228
    • Svenningsson, P.1    Lindskog, M.2    Rognoni, F.3    Fredholm, B.B.4    Greengard, P.5    Fisone, G.6
  • 48
    • 0028331291 scopus 로고
    • Rostrocaudal subregional differences in the response of enkephalin, dynorphin and substance P synthesis in rat nucleus accumbens to dopamine depletion
    • Voorn P., Docter G.J., Jongen-Relo A.L., Jonker A.J. Rostrocaudal subregional differences in the response of enkephalin, dynorphin and substance P synthesis in rat nucleus accumbens to dopamine depletion. Eur. J. Neurosci. 6:1994;486-496
    • (1994) Eur. J. Neurosci. , vol.6 , pp. 486-496
    • Voorn, P.1    Docter, G.J.2    Jongen-Relo, A.L.3    Jonker, A.J.4
  • 49
    • 0035341258 scopus 로고    scopus 로고
    • Preferential cytoplasmic localization of delta-opioid receptors in rat striatal patches: Comparison with plasmalemmal mu-opioid receptors
    • Wang H., Pickel V.M. Preferential cytoplasmic localization of delta-opioid receptors in rat striatal patches: comparison with plasmalemmal mu-opioid receptors. J. Neurosci. 21:2001;3242-3250
    • (2001) J. Neurosci. , vol.21 , pp. 3242-3250
    • Wang, H.1    Pickel, V.M.2
  • 50
    • 0033552067 scopus 로고    scopus 로고
    • Mu-opioid and NMDA-type glutamate receptors are often colocalized in spiny neurons within patches of the caudate-putamen nucleus
    • Wang H., Gracy K.N., Pickel V.M. Mu-opioid and NMDA-type glutamate receptors are often colocalized in spiny neurons within patches of the caudate-putamen nucleus. J. Comp. Neurol. 412:1999;132-146
    • (1999) J. Comp. Neurol. , vol.412 , pp. 132-146
    • Wang, H.1    Gracy, K.N.2    Pickel, V.M.3
  • 51
    • 0035138995 scopus 로고    scopus 로고
    • Cellular and synaptic adaptations mediating opioid dependence
    • Williams J.T., Christie M.J., Manzoni O. Cellular and synaptic adaptations mediating opioid dependence. Physiol. Rev. 81:2001;299-343
    • (2001) Physiol. Rev. , vol.81 , pp. 299-343
    • Williams, J.T.1    Christie, M.J.2    Manzoni, O.3
  • 52
    • 0030857109 scopus 로고    scopus 로고
    • Involvement of cAMP-dependent protein kinase in mu-opioid modulation of NMDA-mediated synaptic currents
    • Xie C.W., Lewis D.V. Involvement of cAMP-dependent protein kinase in mu-opioid modulation of NMDA-mediated synaptic currents. J. Neurophysiol. 78:1997;759-766
    • (1997) J. Neurophysiol. , vol.78 , pp. 759-766
    • Xie, C.W.1    Lewis, D.V.2
  • 53
    • 0028988176 scopus 로고
    • Chronic L-DOPA treatment differentially regulates gene expression of glutamate decarboxylase, preproenkephalin and preprotachykinin in the striatum of 6-hydroxydopamine-lesioned rat
    • Zeng B.Y., Jolkkonen J., Jenner P., Marsden C.D. Chronic L-DOPA treatment differentially regulates gene expression of glutamate decarboxylase, preproenkephalin and preprotachykinin in the striatum of 6-hydroxydopamine- lesioned rat. Neuroscience. 66:1995;19-28
    • (1995) Neuroscience , vol.66 , pp. 19-28
    • Zeng, B.Y.1    Jolkkonen, J.2    Jenner, P.3    Marsden, C.D.4


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