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Volumn 6, Issue 2, 2004, Pages 103-110

Vascular targeting agents

Author keywords

[No Author keywords available]

Indexed keywords

5,6 DIMETHYLXANTHENONE 4 ACETIC ACID; ANGIOGENESIS INHIBITOR; ANTIMITOTIC AGENT; ANTINEOPLASTIC AGENT; AVE 8062A; BLEOMYCIN; CISPLATIN; COLCHICINE; COMBRETASTATIN A4 PHOSPHATE; CONTRAST MEDIUM; CYTOTOXIC AGENT; FLAVONOID; GADOLINIUM; MITOFLAXONE; MITOFLAXONE 2 DIETHYLAMINOETHYL ESTER; MONOCLONAL ANTIBODY HUJ591; N ACETYLCOLCHINOL PHOSPHATE; N [2 [(4 HYDROXYPHENYL)AMINO] 3 PYRIDINYL] 4 METHOXYBENZENESULFONAMIDE; NSC 640888; PACLITAXEL; PHOSPHATIDYLSERINE INHIBITOR; PROSTATE SPECIFIC MEMBRANE ANTIGEN INHIBITOR; THALIDOMIDE; TISSUE FACTOR PATHWAY INHIBITOR; TUBULIN BINDING AGENT; UNCLASSIFIED DRUG; UNINDEXED DRUG; VASCULAR CELL ADHESION MOLECULE 1 INHIBITOR; VASCULAR TARGETING AGENT; VASCULOTROPIN; VINBLASTINE; VINCRISTINE; TUBULIN; TUBULIN MODULATOR;

EID: 2342564355     PISSN: 15233790     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11912-004-0021-6     Document Type: Review
Times cited : (7)

References (56)
  • 1
    • 0034648765 scopus 로고    scopus 로고
    • Angiogenesis in cancer and other diseases
    • Carmeliet P, Jain RK: Angiogenesis in cancer and other diseases. Nature 2000, 407:249-257.
    • (2000) Nature , vol.407 , pp. 249-257
    • Carmeliet, P.1    Jain, R.K.2
  • 2
    • 0038637355 scopus 로고    scopus 로고
    • Vascular targeting agents: Horizons in cancer therapeutics: From bench to bedside
    • Siemann DW: Vascular targeting agents: horizons in cancer therapeutics: from bench to bedside 2002, 3:4-15.
    • (2002) , vol.3 , pp. 4-15
    • Siemann, D.W.1
  • 3
    • 0036173591 scopus 로고    scopus 로고
    • Hypoxia as a target for combined modality treatments
    • Chiu RK, Lambin P: Hypoxia as a target for combined modality treatments. Eur J Cancer 2002, 38:240-257.
    • (2002) Eur. J. Cancer , vol.38 , pp. 240-257
    • Chiu, R.K.1    Lambin, P.2
  • 4
    • 85013312416 scopus 로고
    • Tumor angiogenesis: Therapeutic implications
    • Folkman J: Tumor angiogenesis: therapeutic implications. N Engl J Med 1971, 285:1182-1186.
    • (1971) N. Engl. J. Med. , vol.285 , pp. 1182-1186
    • Folkman, J.1
  • 5
    • 0034975263 scopus 로고    scopus 로고
    • Antiangiogenic agents and their promising potential in combined therapy
    • Burke PA, DeNardo SJ: Antiangiogenic agents and their promising potential in combined therapy. Crit Rev Oncol Hematol 2001, 39:155-171.
    • (2001) Crit. Rev. Oncol. Hematol. , vol.39 , pp. 155-171
    • Burke, P.A.1    DeNardo, S.J.2
  • 6
    • 0029686918 scopus 로고    scopus 로고
    • Tumor angiogenesis and the role of vascular cell integrin alphavbeta3
    • Edited by DeVita VT, Hellman S, Rosenbery SA. Philadelphia: Lippincott-Raven
    • Varner JA, Cheresh DA: Tumor angiogenesis and the role of vascular cell integrin alphavbeta3. In Important Advances in Oncology. Edited by DeVita VT, Hellman S, Rosenbery SA. Philadelphia: Lippincott-Raven; 1996:69-87.
    • (1996) Important Advances in Oncology , pp. 69-87
    • Varner, J.A.1    Cheresh, D.A.2
  • 7
    • 0042887593 scopus 로고    scopus 로고
    • Assessment of pharmacodynamic vascular response in a phase I trial of combrestatin A4 phosphate
    • Anderson HL, Yap JT, Miller MP, et al.: Assessment of pharmacodynamic vascular response in a phase I trial of combrestatin A4 phosphate. J Clin Oncol 2003, 21:2823-2830.
    • (2003) J. Clin. Oncol. , vol.21 , pp. 2823-2830
    • Anderson, H.L.1    Yap, J.T.2    Miller, M.P.3
  • 8
    • 2342548069 scopus 로고    scopus 로고
    • Vascular targeting: Clinical experience: Horizons in cancer therapeutics: From bench to bedside
    • Remick SC: Vascular targeting: clinical experience: horizons in cancer therapeutics: from bench to bedside 2002, 3:16-23.
    • (2002) , vol.3 , pp. 16-23
    • Remick, S.C.1
  • 9
    • 0025093973 scopus 로고
    • Vascular attack as a therapeutic strategy for cancer
    • Denekamp J: Vascular attack as a therapeutic strategy for cancer. Cancer Metastasis Rev 1990, 9:267-282.
    • (1990) Cancer Metastasis Rev. , vol.9 , pp. 267-282
    • Denekamp, J.1
  • 10
    • 0037373826 scopus 로고    scopus 로고
    • The first international conference on vascular targeting: Meeting overview
    • Thorpe PE, Chaplin DJ, Blakey DC: The first international conference on vascular targeting: meeting overview. Cancer Res 2003, 63:1144-1147.
    • (2003) Cancer Res. , vol.63 , pp. 1144-1147
    • Thorpe, P.E.1    Chaplin, D.J.2    Blakey, D.C.3
  • 11
    • 0036891515 scopus 로고    scopus 로고
    • The development of combretastatin A4 phosphate as a vascular targeting agent
    • Chaplin DJ, Hill SA: The development of combretastatin A4 phosphate as a vascular targeting agent. Int J Radiat Oncol Biol Phys 2002, 54:1491-1496.
    • (2002) Int. J. Radiat. Oncol. Biol. Phys. , vol.54 , pp. 1491-1496
    • Chaplin, D.J.1    Hill, S.A.2
  • 13
    • 0000742387 scopus 로고
    • A critique of tumor resistance
    • Wolfrum WH: A critique of tumor resistance. J Cancer Res 1923, 7:283-31.
    • (1923) J. Cancer Res. , vol.7 , pp. 283-331
    • Wolfrum, W.H.1
  • 15
    • 0031026481 scopus 로고    scopus 로고
    • Tumor infarction in mice by antibody-directed targeting of tissue factor to tumor vasculature
    • Huang X, Molema G, King S, et al.: Tumor infarction in mice by antibody-directed targeting of tissue factor to tumor vasculature. Science 1997, 275:547-550.
    • (1997) Science , vol.275 , pp. 547-550
    • Huang, X.1    Molema, G.2    King, S.3
  • 16
    • 0033168844 scopus 로고    scopus 로고
    • Five different antiprostate-specific membrane antigen (PSMA) antibodies confirm PSMA expression in tumor-associated vasculature
    • Chang SS, Reuter VE, Heston WD, et al.: Five different antiprostate-specific membrane antigen (PSMA) antibodies confirm PSMA expression in tumor-associated vasculature. Cancer Res 1999, 59:3192-3198.
    • (1999) Cancer Res. , vol.59 , pp. 3192-3198
    • Chang, S.S.1    Reuter, V.E.2    Heston, W.D.3
  • 17
    • 0012648073 scopus 로고    scopus 로고
    • Anti-PSMA mAB huJ591 specifically targets tumor vascular endothelial cells with advanced solid tumor malignancies
    • [abstract]
    • Milowsky MI, Rosmarin AS, Cobham MV, et al.: Anti-PSMA mAB huJ591 specifically targets tumor vascular endothelial cells with advanced solid tumor malignancies [abstract]. Proc ASCO 2002, 21:29.
    • (2002) Proc. ASCO , vol.21 , pp. 29
    • Milowsky, M.I.1    Rosmarin, A.S.2    Cobham, M.V.3
  • 18
    • 0001851181 scopus 로고
    • Colchicine in the experimental chemotherapy of cancer
    • Ludford RJ: Colchicine in the experimental chemotherapy of cancer. J Natl Cancer Inst 1945, 6:89-101.
    • (1945) J. Natl. Cancer Inst. , vol.6 , pp. 89-101
    • Ludford, R.J.1
  • 19
    • 0016723594 scopus 로고
    • An endotoxin-induced serum factor that causes necrosis of tumors
    • Carswell EA, Old LJ, Kassel RL, et al.: An endotoxin-induced serum factor that causes necrosis of tumors. Proc Natl Acad Sci U S A 1975, 25:3666-3670.
    • (1975) Proc. Natl. Acad. Sci. USA , vol.25 , pp. 3666-3670
    • Carswell, E.A.1    Old, L.J.2    Kassel, R.L.3
  • 21
    • 0025076479 scopus 로고
    • Role of tumor necrosis factor in flavone acetic acid-induced tumor vascular shutdown
    • Mahadevan V, Malik ST, Meager A, et al.: Role of tumor necrosis factor in flavone acetic acid-induced tumor vascular shutdown. Cancer Res 1990, 50:5537-5542.
    • (1990) Cancer Res. , vol.50 , pp. 5537-5542
    • Mahadevan, V.1    Malik, S.T.2    Meager, A.3
  • 22
    • 0022529486 scopus 로고
    • Phase I and pharmacokinetic study of LM985 (flavone acetic acid ester)
    • Kerr DJ, Kaye SB, Graham J, et al.: Phase I and pharmacokinetic study of LM985 (flavone acetic acid ester). Cancer Res 1986, 46:142-146.
    • (1986) Cancer Res. , vol.46 , pp. 142-146
    • Kerr, D.J.1    Kaye, S.B.2    Graham, J.3
  • 23
    • 0023608388 scopus 로고
    • Phase I and pharmacokinetic study of flavone acetic acid
    • Kerr DJ, Kaye SB, Cassidy J, et al.: Phase I and pharmacokinetic study of flavone acetic acid. Cancer Res 1987, 47:6776-6781.
    • (1987) Cancer Res. , vol.47 , pp. 6776-6781
    • Kerr, D.J.1    Kaye, S.B.2    Cassidy, J.3
  • 24
    • 0027459147 scopus 로고
    • Flavone acetic acid: From laboratory to clinic and back
    • Bibby MC, Double JA: Flavone acetic acid: from laboratory to clinic and back. Anticancer Drugs 1993, 4:3-17.
    • (1993) Anticancer Drugs , vol.4 , pp. 3-17
    • Bibby, M.C.1    Double, J.A.2
  • 25
    • 0037106501 scopus 로고    scopus 로고
    • Effects of 5,6-dimethylxanthenone-4-acetic acid on human tumor microcirculation assessed by dynamic contrast-enhanced magnetic resonance imaging
    • Galbraith SM, Rustin GJS, Lodge MA, et al.: Effects of 5,6-dimethylxanthenone-4-acetic acid on human tumor microcirculation assessed by dynamic contrast-enhanced magnetic resonance imaging. J Clin Oncol 2002, 20:3826-3840.
    • (2002) J. Clin. Oncol. , vol.20 , pp. 3826-3840
    • Galbraith, S.M.1    Rustin, G.J.S.2    Lodge, M.A.3
  • 26
    • 0026079805 scopus 로고
    • Potential antitumor agents. 63. Structure-activity relationships for side-chain analogues of colon 38 active agent 9-oxo-9H-xanthene-4-acetic acid
    • Rewcastle GW, Atwell GJ, Baguley BC, et al.: Potential antitumor agents. 63. Structure-activity relationships for side-chain analogues of colon 38 active agent 9-oxo-9H-xanthene-4-acetic acid. J Med Chem 1991, 34:2864-2870.
    • (1991) J. Med. Chem. , vol.34 , pp. 2864-2870
    • Rewcastle, G.W.1    Atwell, G.J.2    Baguley, B.C.3
  • 27
    • 0030002174 scopus 로고    scopus 로고
    • Ablation of colorectal xenografts with combined radioimmunotherapy and tumor blood flow-modifying agents
    • Pedley RB, Boden JA, Boden R, et al.: Ablation of colorectal xenografts with combined radioimmunotherapy and tumor blood flow-modifying agents. Cancer Res 1996, 56:3293-3300.
    • (1996) Cancer Res. , vol.56 , pp. 3293-3300
    • Pedley, R.B.1    Boden, J.A.2    Boden, R.3
  • 28
    • 0036568457 scopus 로고    scopus 로고
    • Vascular targeting agents enhance chemotherapeutic agent activities in solid tumor therapy
    • Siemann DW, Mercer E, Lepler S, et al.: Vascular targeting agents enhance chemotherapeutic agent activities in solid tumor therapy. Int J Cancer 2002, 99:1-6.
    • (2002) Int. J. Cancer , vol.99 , pp. 1-6
    • Siemann, D.W.1    Mercer, E.2    Lepler, S.3
  • 29
    • 0028280239 scopus 로고
    • Induction of tumor necrosis factor-alpha messenger RNA in human and murine cells by the flavone acetic acid analogue 5,6-dimethylxanthenone-4-acetic acid (NSC 640488)
    • Ching LM, Joseph WR, Crosier RE, et al.: Induction of tumor necrosis factor-alpha messenger RNA in human and murine cells by the flavone acetic acid analogue 5,6-dimethylxanthenone-4-acetic acid (NSC 640488). Cancer Res 1994, 54:870-872.
    • (1994) Cancer Res. , vol.54 , pp. 870-872
    • Ching, L.M.1    Joseph, W.R.2    Crosier, R.E.3
  • 30
    • 0030663473 scopus 로고    scopus 로고
    • Production of tumour necrosis factor-alpha by cultured human peripheral blood leucocytes in response to the anti-tumour agent 5,6-dimethylxanthenone-4-acetic acid (NSC 640488)
    • Philpott M, Joseph WR, Crosier KE, et al.: Production of tumour necrosis factor-alpha by cultured human peripheral blood leucocytes in response to the anti-tumour agent 5,6-dimethylxanthenone-4-acetic acid (NSC 640488). Br J Cancer 1997, 76:1586-1591.
    • (1997) Br. J. Cancer , vol.76 , pp. 1586-1591
    • Philpott, M.1    Joseph, W.R.2    Crosier, K.E.3
  • 31
    • 0038575250 scopus 로고    scopus 로고
    • Clinical aspects of a phase I trial of 5,6-dimethylxanthenone-4-acetic acid (DMXAA), a novel antivascular agent
    • Jameson MB, Thompson PI, Baguley BC, et al.: Clinical aspects of a phase I trial of 5,6-dimethylxanthenone-4-acetic acid (DMXAA), a novel antivascular agent. Br J Cancer 2003, 88:1844-1850.
    • (2003) Br. J. Cancer , vol.88 , pp. 1844-1850
    • Jameson, M.B.1    Thompson, P.I.2    Baguley, B.C.3
  • 32
    • 0001296910 scopus 로고    scopus 로고
    • Combination of the antivascular agent DMXAA with radiation and chemotherapy
    • Wilson WR, BC Baguley: Combination of the antivascular agent DMXAA with radiation and chemotherapy. Int J Radiat Oncol Biol Phys 2000, 46:706.
    • (2000) Int. J. Radiat. Oncol. Biol. Phys. , vol.46 , pp. 706
    • Wilson, W.R.1    Baguley, B.C.2
  • 33
    • 0037222218 scopus 로고    scopus 로고
    • Marked potentiation of the antitumour activity of chemotherapy drugs by the antivascular agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA)
    • Siim BG, Pruijn FB, Shalal-Zwain S, et al.: Marked potentiation of the antitumour activity of chemotherapy drugs by the antivascular agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA). Cancer Chemother Pharmacol 2003, 51:43-52.
    • (2003) Cancer Chemother. Pharmacol. , vol.51 , pp. 43-52
    • Siim, B.G.1    Pruijn, F.B.2    Shalal-Zwain, S.3
  • 34
    • 0028234390 scopus 로고
    • Combining bioreductive drugs (SR4233 or SN23862) with the vasoreactive agents flavone acetic acid or 5,6-dimethylxanthenone-4-acetic acid
    • Cliffe S, Taylor ML, Rutland M, et al.: Combining bioreductive drugs (SR4233 or SN23862) with the vasoreactive agents flavone acetic acid or 5,6-dimethylxanthenone-4-acetic acid. Int J Radiat Oncol Biol Phys 1994, 24:373-377.
    • (1994) Int. J. Radiat. Oncol. Biol. Phys. , vol.24 , pp. 373-377
    • Cliffe, S.1    Taylor, M.L.2    Rutland, M.3
  • 35
    • 0031858141 scopus 로고    scopus 로고
    • Enhancement of the anti-tumour effects of the antivascular agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA) by combination wit h5-hydroxytryptamine and bioreductive drugs
    • Lash CJ, LI AE, Rutland M, et al.: Enhancement of the anti-tumour effects of the antivascular agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA) by combination wit h5-hydroxytryptamine and bioreductive drugs. Br J Cancer 1998, 78:439-445.
    • (1998) Br. J. Cancer , vol.78 , pp. 439-445
    • Lash, C.J.1    Li, A.E.2    Rutland, M.3
  • 36
    • 0036891507 scopus 로고    scopus 로고
    • Synergy between vascular targeting agents and antibody-directed therapy
    • Pedley RB, El-Emir E, Flynn A, et al.: Synergy between vascular targeting agents and antibody-directed therapy. Int J Radiat Oncol Biol Phys 2002, 54:1524-1531.
    • (2002) Int. J. Radiat. Oncol. Biol. Phys. , vol.54 , pp. 1524-1531
    • Pedley, R.B.1    El-Emir, E.2    Flynn, A.3
  • 37
    • 0032895102 scopus 로고    scopus 로고
    • Thalidomide increases both intra-tumoral tumour necrosis factor-alpha production and anti-tumour activity in response to 5,6-dimethylxanthenone-4-acetic acid
    • Cao Z, Joseph WR, Browne WL, et al.: Thalidomide increases both intra-tumoral tumour necrosis factor-alpha production and anti-tumour activity in response to 5,6-dimethylxanthenone-4-acetic acid. Br J Cancer 1999, 80:716-723.
    • (1999) Br. J. Cancer , vol.80 , pp. 716-723
    • Cao, Z.1    Joseph, W.R.2    Browne, W.L.3
  • 38
    • 0035266136 scopus 로고    scopus 로고
    • Vascular attack by 5,6-dimethylxanthenone-4-acetic acid combined with B7.1 (CD80)-mediated immunotherapy overcomes immune resistance and leads to eradication of large tumors and multiple tumor foci
    • Kanwar JR, Danwar RK, Pandey S, et al.: Vascular attack by 5,6-dimethylxanthenone-4-acetic acid combined with B7.1 (CD80)-mediated immunotherapy overcomes immune resistance and leads to eradication of large tumors and multiple tumor foci. Cancer Res 2001, 61:1948-1956.
    • (2001) Cancer Res. , vol.61 , pp. 1948-1956
    • Kanwar, J.R.1    Danwar, R.K.2    Pandey, S.3
  • 39
    • 0029800934 scopus 로고    scopus 로고
    • Antitumor activity of combretastatin-A4 phosphate, a natural product tubulin inhibitor
    • Dorr T: Dvorakova K, Snead K, et al.: Antitumor activity of combretastatin-A4 phosphate, a natural product tubulin inhibitor. Invest New Drugs 1996, 14:131-137.
    • (1996) Invest. New Drugs , vol.14 , pp. 131-137
    • Dorr, T.1    Dvorakova, K.2    Snead, K.3
  • 40
    • 0042386700 scopus 로고    scopus 로고
    • Phase I clinical trial of weekly combretastatin A4 phosphate: Clinical and pharmacokinetic results
    • Rustin GJS, Galbraith SM, Anderson H, et al.: Phase I clinical trial of weekly combretastatin A4 phosphate: clinical and pharmacokinetic results. J Clin Oncol 2003, 21:2815-2822.
    • (2003) J. Clin. Oncol. , vol.21 , pp. 2815-2822
    • Rustin, G.J.S.1    Galbraith, S.M.2    Anderson, H.3
  • 41
    • 0031770618 scopus 로고    scopus 로고
    • The effect of combretastatin A-4 phosphate in a C3H mouse mammary carcinoma and a variety of murine spontaneous tumors
    • Horsman MR, Ehrnrooth E, Laderkarl M, et al.: The effect of combretastatin A-4 phosphate in a C3H mouse mammary carcinoma and a variety of murine spontaneous tumors. Int J Radiat Oncol Biol Phys 1998, 42:895-989.
    • (1998) Int. J. Radiat. Oncol. Biol. Phys. , vol.42 , pp. 895-989
    • Horsman, M.R.1    Ehrnrooth, E.2    Laderkarl, M.3
  • 42
    • 0030951899 scopus 로고    scopus 로고
    • Combretastatin A-4, an agent that displays potent and selective toxicity toward tumor vasculature
    • Dark GG, Hill SA, Prise VE, et al.: Combretastatin A-4, an agent that displays potent and selective toxicity toward tumor vasculature. Cancer Res 1997, 57:1829-1834.
    • (1997) Cancer Res. , vol.57 , pp. 1829-1834
    • Dark, G.G.1    Hill, S.A.2    Prise, V.E.3
  • 43
    • 0032532391 scopus 로고    scopus 로고
    • Induction of apoptosis in proliferating human endothelial cells by tumor-specific antiangiogenesis agent combretastatin A-4
    • Iyer S, Chaplin DJ, Rosenthal DS, et al.: Induction of apoptosis in proliferating human endothelial cells by tumor-specific antiangiogenesis agent combretastatin A-4. Cancer Res 1998, 58:4510-4514.
    • (1998) Cancer Res. , vol.58 , pp. 4510-4514
    • Iyer, S.1    Chaplin, D.J.2    Rosenthal, D.S.3
  • 44
    • 0034906627 scopus 로고    scopus 로고
    • Combretastatin A4 prodrug study of effect on the growth and microvasculature of colorectal liver metastases in a murine model
    • Malcontenti-Wilson C, Muralidharan V, Skinner S, et al.: Combretastatin A4 prodrug study of effect on the growth and microvasculature of colorectal liver metastases in a murine model. Clin Cancer Res 2001, 7:1052-1060.
    • (2001) Clin. Cancer Res. , vol.7 , pp. 1052-1060
    • Malcontenti-Wilson, C.1    Muralidharan, V.2    Skinner, S.3
  • 45
    • 0032950870 scopus 로고    scopus 로고
    • Anti-vascular approaches to solid tumour therapy: Evaluation of combretastatin A4 phosphate
    • Chaplin DJ, Pettit GR, Hill SA: Anti-vascular approaches to solid tumour therapy: evaluation of combretastatin A4 phosphate. Anticancer Res 1999, 19:189-195.
    • (1999) Anticancer Res. , vol.19 , pp. 189-195
    • Chaplin, D.J.1    Pettit, G.R.2    Hill, S.A.3
  • 46
    • 0037096814 scopus 로고    scopus 로고
    • A phase I pharmacokinetic and translational study of the novel vascular targeting agent combretastatin A-4 phosphate on a single-dose intravenous schedule in patients with advanced cancer
    • Dotwali A, Robertson K, Cooney M, et al.: A phase I pharmacokinetic and translational study of the novel vascular targeting agent combretastatin A-4 phosphate on a single-dose intravenous schedule in patients with advanced cancer. Cancer Res 2002, 62:3408-3416.
    • (2002) Cancer Res. , vol.62 , pp. 3408-3416
    • Dotwali, A.1    Robertson, K.2    Cooney, M.3
  • 47
    • 0035889331 scopus 로고    scopus 로고
    • Combretastatin A-4 disodium phosphate: A vascular targeting agent that improves the anti-tumor effects of hyperthermia, radiation and mild hyperthermia
    • Murata R, Overgaard J, Horsman MR: Combretastatin A-4 disodium phosphate: a vascular targeting agent that improves the anti-tumor effects of hyperthermia, radiation and mild hyperthermia. Int J Radiat Oncol Bio Phys, 2002, 51:1018-102.
    • (2002) Int. J. Radiat. Oncol. Bio. Phys. , vol.51 , pp. 1018-1102
    • Murata, R.1    Overgaard, J.2    Horsman, M.R.3
  • 48
    • 0042386691 scopus 로고    scopus 로고
    • Combrestatin A4 phosphate has tumor antivascular activity in rat and man as demonstrated by dynamic contrast-enhanced magnetic resonance imaging
    • Galbraith SM, Maxwell RJ, Lodge MA, et al.: Combrestatin A4 phosphate has tumor antivascular activity in rat and man as demonstrated by dynamic contrast-enhanced magnetic resonance imaging. J Clin Oncol 2003, 21:2831-2842.
    • (2003) J. Clin. Oncol. , vol.21 , pp. 2831-2842
    • Galbraith, S.M.1    Maxwell, R.J.2    Lodge, M.A.3
  • 49
    • 0842265381 scopus 로고    scopus 로고
    • Phase I, pharmacokinetic and DCE-MRI correlative study of AVE8062A, an antivascular combretastatin analogue, administered weekly for 3 weeks every 28 days [abstract]
    • Tolcher AW, Forero L, Celio P, et al.: Phase I, pharmacokinetic and DCE-MRI correlative study of AVE8062A, an antivascular combretastatin analogue, administered weekly for 3 weeks every 28 days [abstract]. Proc ASCO, 2003, 22:834.
    • (2003) Proc. ASCO , vol.22 , pp. 834
    • Tolcher, A.W.1    Forero, L.2    Celio, P.3
  • 50
    • 0011454948 scopus 로고    scopus 로고
    • In vivo antitumor activity and tumor necrosis induced by AVE8062A, a tumor vasculature targeting agent
    • Presented at the 93rd annual conference of the American Association for Cancer Research. April 6-10, San Francisco, CA; abstract
    • Lejeune P, Hodge TG, Vrignaud P, et al.: In vivo antitumor activity and tumor necrosis induced by AVE8062A, a tumor vasculature targeting agent. Presented at the 93rd annual conference of the American Association for Cancer Research. April 6-10, 2002, San Francisco, CA; abstract 781.
    • (2002) , pp. 781
    • Lejeune, P.1    Hodge, T.G.2    Vrignaud, P.3
  • 51
    • 0036278972 scopus 로고    scopus 로고
    • Antitumor activity of the novel vascular targeting agent ZD6126 in a panel of tumor models
    • Blakey DC, Westwood FR, Walker M, et al.: Antitumor activity of the novel vascular targeting agent ZD6126 in a panel of tumor models. Clin Cancer Res 2002, 8:1974-1983.
    • (2002) Clin. Cancer Res. , vol.8 , pp. 1974-1983
    • Blakey, D.C.1    Westwood, F.R.2    Walker, M.3
  • 52
    • 0012692946 scopus 로고    scopus 로고
    • A dose escalation study of the novel vascular targeting agent, ZD6126 in patients with solid tumors
    • [abstract]
    • Gadgeel SM, LoRusso PM, Wozniak AJ, et al.: A dose escalation study of the novel vascular targeting agent, ZD6126 in patients with solid tumors [abstract]. Proc ASCO 2002, 21:438.
    • (2002) Proc. ASCO , vol.21 , pp. 438
    • Gadgeel, S.M.1    LoRusso, P.M.2    Wozniak, A.J.3
  • 53
    • 0038599016 scopus 로고    scopus 로고
    • Clinical evaluation of the novel vascular-targeting agent, ZD6126: Assessment of toxicity and surrogate markers of vascular damage
    • [abstract]
    • Radema SA, Beerepoot LV, Wittevee PO, et al.: Clinical evaluation of the novel vascular-targeting agent, ZD6126: assessment of toxicity and surrogate markers of vascular damage [abstract]. Proc ASCO 2002, 21:439.
    • (2002) Proc. ASCO , vol.21 , pp. 439
    • Radema, S.A.1    Beerepoot, L.V.2    Wittevee, P.O.3
  • 54
    • 0013405842 scopus 로고    scopus 로고
    • MRI evaluation of the effect of the vascular targeting agent ZD6126 on tumor vasculature
    • [abstract]
    • DelProposto Z, LoRusso P, Latif Z, et al.: MRI evaluation of the effect of the vascular targeting agent ZD6126 on tumor vasculature [abstract]. Proc ASCO 2002, 21:440.
    • (2002) Proc. ASCO , vol.21 , pp. 440
    • DelProposto, Z.1    LoRusso, P.2    Latif, Z.3
  • 55
    • 4344686435 scopus 로고    scopus 로고
    • Pharmacokinetics and safety profile of ABT-751, a novel microtubulin inhibitor
    • [abstract]
    • Hande KR, Meek K, Lockhart AC, et al.: Pharmacokinetics and safety profile of ABT-751, a novel microtubulin inhibitor [abstract]. Proc ASCO 2003, 22:520.
    • (2003) Proc. ASCO , vol.22 , pp. 520
    • Hande, K.R.1    Meek, K.2    Lockhart, A.C.3
  • 56
    • 0011468858 scopus 로고    scopus 로고
    • A novel anti-tubulin agent (ABT-751) selectively reduces tumor perfusion in a subcutaneous rat tumor model as measured by MRI
    • Presented at the 93rd annual conference of the American Association for Cancer Research. April 6-10, San Francisco, CA; abstract
    • Luo Y, Mohning KM, Nuss ME, et al.: A novel anti-tubulin agent (ABT-751) selectively reduces tumor perfusion in a subcutaneous rat tumor model as measured by MRI. Presented at the 93rd annual conference of the American Association for Cancer Research. April 6-10, 2002, San Francisco, CA; abstract 784.
    • (2002) , pp. 784
    • Luo, Y.1    Mohning, K.M.2    Nuss, M.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.