Structural basis for differential recognition of tyrosine-phosphorylated sites in the linker for activation of T cells (LAT) by the adaptor Gads

EMBO Journal

Volumn 23, Issue 7, 2004, Pages 1441-1451

  Cho, Sangwoo ^a   Velikovsky, C Alejandro ^a   Swaminathan, Chittoor P ^a   Houtman, Jon C D ^b   Samelson, Lawrence E ^b   Mariuzza, Roy A ^a  

^a UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Gads; Grb2; LAT; SH2 domain; Tyrosine phosphorylation

Indexed keywords

ADAPTOR PROTEIN; ASPARAGINE; GROWTH FACTOR RECEPTOR BOUND PROTEIN 2; LAT PROTEIN; PROTEIN GAD; TYROSINE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING SITE; CALORIMETRY; CARBOXY TERMINAL SEQUENCE; CRYSTAL STRUCTURE; LYMPHOCYTE FUNCTION; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN BINDING; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; GRB2 ADAPTOR PROTEIN; HUMANS; MEMBRANE PROTEINS; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MULTIPROTEIN COMPLEXES; PHOSPHOPEPTIDES; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN CONFORMATION; SRC HOMOLOGY DOMAINS; THERMODYNAMICS; TYROSINE;

EID: 2342558054     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.emboj.7600168     Document Type: Article

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