Orphanin FQ/nociceptin suppresses motor activity through an action along the mesoaccumbens axis in rats

Journal of Psychiatry and Neuroscience

Volumn 29, Issue 2, 2004, Pages 116-123

  Narayanan, Shridhar ^a   Lam, Hoa ^a   Carroll, F Ivy ^b   Lutfy, Kabirullah ^a,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b RTI INTERNATIONAL   (United States)

^c WESTERN UNIVERSITY OF HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 (1 CYCLOOCTYLMETHYL 3 HYDROXYMETHYL 4 PIPERIDYL) 3 ETHYL 1,3 DIHYDRO 2H BENZIMIDAZOL 2 ONE; BENZIMIDAZOLE DERIVATIVE; NOCICEPTIN; OPIATE RECEPTOR; OPIOID RECEPTOR LIKE RECEPTOR; OPIOID RECEPTOR LIKE RECEPTOR ANTAGONIST; RECEPTOR BLOCKING AGENT; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ARTICLE; BRAIN REGION; CANNULA; CEREBROSPINAL FLUID; CONTROLLED STUDY; CORPUS STRIATUM; DOPAMINERGIC NERVE CELL; DOSE RESPONSE; HABITUATION; MALE; MOTOR ACTIVITY; NEUROMODULATION; NONHUMAN; NUCLEUS ACCUMBENS; RAT; SUBSTANTIA NIGRA; VENTRAL TEGMENTUM;

ANIMALS; CORPUS STRIATUM; LOCOMOTION; MALE; NUCLEUS ACCUMBENS; OPIOID PEPTIDES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, OPIOID; SUBSTANTIA NIGRA;

EID: 2342518737     PISSN: 11804882     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (37)

1. Meunier JC, Mollereau C, Toll L, Suaudeau C, Moisand C, Alvinerie P, et al. Isolation and structure of the endogenous agonist of opioid receptor-like ORL1 receptor. Nature 1995;377:532-5.
2. Reinscheid RK, Nothacker HP, Bourson A, Ardati A, Henningsen RA, Bunzow JR, et al. Orphanin FQ: a neuropeptide that activates an opioidlike G protein-coupled receptor. Science 1995;270:792-4.
3. Bunzow JR, Saez C, Mortrud M, Bouvier C, Williams JT, Low M, et al. Molecular cloning and tissue distribution of a putative member of the rat opioid receptor gene family that is not a mu, delta or kappa opioid receptor type. FEBS Lett 1994;347:284-8.
4. Chen Y, Fan Y, Liu J, Mestek A, Tian M, Kozak CA, et al. Molecular cloning, tissue distribution and chromosomal localization of a novel member of the opioid receptor gene family. FEBS Lett 1994;347:279-83.
5. Fukuda K, Kato S, Mori K, Nishi M, Takeshima H, Iwabe N, et al. cDNA cloning and regional distribution of a novel member of the opioid receptor family. FEBS Lett 1994;343:42-6.
6. Mollereau C, Parmentier M, Mailleux P, Butour JL, Moisand C, Chalon P, et al. ORL1, a novel member of the opioid receptor family. Cloning, functional expression and localization. FEBS Lett 1994;341:33-8.
7. 2+ in the SH-SY5Y human neuroblastoma cell line. Br J Pharmacol 1996;118:205-7.
8. Knoflach F, Reinscheid RK, Civelli O, Kemp JA. Modulation of voltage-gated calcium channels by orphanin FQ in freshly dissociated hippocampal neurons. J Neurosci 1996;16:6657-64.
9. Connor M, Vaughan CW, Chieng B, Christie MJ. Nociceptin receptor coupling to a potassium conductance in rat locus coeruleus neurones in vitro. Br J Pharmacol 1996;119:1614-8.
10. Matthes H, Seward EJ, Kieffer B, North A. Functional selectivity of orphanin FQ for its receptor coexpressed with potassium channel subunits in Xenopus laevis oocytes. Mol Pharmacol 1996;50:447-50.
11. Vaughan CW, Christie MJ. Increase by the ORL1 receptor (opioid receptor-like1) ligand, nociceptin, of inwardly rectifying K conductance in dorsal raphe nucleus neurones. Br J Pharmacol 1996;117:1609-11.
12. Murphy NP, Ly HT, Maidment NT. Intracerebroventricular orphanin FQ/nociceptin suppresses dopamine release in the nucleus accumbens of anaesthetized rats. Neuroscience 1996;75:1-4.
13. Lutfy K, Do T, Maidment NT. Orphanin FQ/nociceptin attenuates motor stimulation and changes in nudeus accumbens extracellular dopamine induced by cocaine in rats. Psychopharmacology (Berl) 2001;154:1-7.
14. Murphy NP, Maidment NT. Orphanin FQ/nociceptin modulation of mesolimbic dopamine transmission determined by microdialysis. J Neurochem 1999;73:179-86.
15. Di Giannuario A, Pieretti S. Nociceptin differentially affects morphine-induced dopamine release from the nucleus accumbens and nucleus caudate in rats. Peptides 2000;21:1125-30.
16. Konya H, Masuda H, Itoh K, Nagai K, Kakishita E, Matsuoka A. Modification of dopamine release by nociceptin in conscious rat striatum. Brain Res 1998;788:341-4.
17. Paxinos G, Watson C. The rat brain in stereotaxic coordinates. 2nd ed. San Diego (CA): Academic Press; 1986.
18. Devine DP, Taylor L, Reinscheid RK, Monsma FJ Jr, Civelli O, Akil H. Rats rapidly develop tolerance to the locomotor-inhibiting effects of the novel neuropeptide orphanin FQ. Neurochem Res 1996;21:1387-96.
19. Lutfy K, Khaliq I, Carroll FI, Maidment NT. Orphanin FQ/nociceptin blocks cocaine-induced behavioral sensitization in rats. Psychopharmacology (Berl) 2002;164:168-76.
20. Maidment NT, Chen Y, Tan AM, Murphy NP, Leslie FM. Rat ventral midbrain dopamine neurons express the orphanin FQ/nociceptin receptor ORL-1. NeuroReport 2002;13:1137-40.
21. Norton CS, Neal CR, Kumar S, Akil H, Watson SJ. Nociceptin/orphanin FQ and opioid receptor-like receptor mRNA expression in dopamine systems. J Comp Neurol 2002;444:358-68.
22. Kawamoto H, Ozaki S, Itoh Y, Miyaji M, Arai S, Nakashima H, et al. Discovery of the first potent and selective small molecule opioid receptor-like (ORL1) antagonist: 1-[(3R,4R)-1-cyclooctylmethyl-3-hydroxymethyl-4-piperidyl]-3- ethyl-1,3-di-hydro-2H-benzimidazol-2-one (J-113397). J Med Chem 1999;42:5061-63.
23. Ozaki S, Kawamoto H, Itoh Y, Miyaji M, Azuma T, Ichikawa D, et al. In vitro and in vivo pharmacological characterization of J-113397, a potent and selective non-peptidyl ORL-1 receptor antagonist. Eur J Pharmacol 2000;402:45-53.
24. Herz A. Opioid reward mechanisms: A key role in drug abuse? Can J Physiol Pharmacol 1998;76:252-8.
25. Koob GF. Drugs of abuse: anatomy, pharmacology and function of reward pathways. Trends Pharmacol Sci 1992;13:177-84.
26. Di Chiara G, Imperato A. Opposite effects of mu and kappa opiate agonists on dopamine release in the nucleus accumbens and in the dorsal caudate of freely moving rats. J Pharmacol Exp Ther 1988;244:1067-80.
27. Johnson SW, North RA. Two types of neurone in the rat ventral tegmental area and their synaptic inputs. J Physiol 1992;450:455-68.
28. Speciale SG, Manaye KF, Sadeq M, German DC. Opioid receptors in midbrain dopaminergic regions of the rat. II. Kappa and delta receptor autoradiography. J Neural Transm Gen Sect 1993;91:53-66.
29. Neal CR Jr, Akil H, Watson SJ Jr. Expression of orphanin FQ and the opioid receptor-like (ORL1) receptor in the developing human and rat brain. J Chem Neuroanat 2001;22:219-49.
30. Spanagel R, Herz A, Shippenberg TS. Opposing tonically active endogenous opioid systems modulate the mesolimbic dopaminergic pathway. Proc Natl Acad Sci U S A 1992;89:2046-50.
31. Narayanan S, Maidment NT. Orphanin FQ and behavioral sensitization to cocaine. Pharmacol Biochem Behav 1999;63:271-7.
32. Zheng F, Grandy DK, Johnson SW. Actions of orphanin FQ/nociceptin on rat ventral tegmental area neurons in vitro. Br J Pharmacol 2002;136:1065-71.
33. Hokfelt T, Ljungdahl A, Fuxe K, Johansson O. Dopamine nerve terminals in the rat limbic cortex: aspects of the dopamine hypothesis of schizophrenia. Science 1974;184:177-9.
34. Matthysse S. Antipsychotic drug actions: A clue to the neuropathology of schizophrenia? Fed Proc 1973;32:200-5.
35. Stevens JR. An anatomy of schizophrenia? Arch Gen Psychiatry 1973;29:177-89.
36. Robinson TE, Berridge KC. The neural basis of drug craving: an incentive-sensitization theory of addiction. Brain Res Rev 1993;18:247-91.
37. Vanderschuren LJ, Kalivas PW. Alterations in dopaminergic and glutamatergic transmission in the induction and expression of behavioral sensitization: a critical review of preclinical studies. Psychopharmacology (Berl) 2002;151:99-120.