Fluorescent microsphere method is suitable for chronic bone blood flow measurement: A long-term study after meniscectomy in rabbits

Journal of Applied Physiology

Volumn 96, Issue 5, 2004, Pages 1928-1936

  Anetzberger, H ^a,b   Thein, E ^a   Loffler G ^a   Messmer, K ^a  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^b Dept of Orthopaedics ^*  (Germany)

Author keywords

Experimental study; Osteoarthritis

Indexed keywords

ACCURACY; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE BLOOD FLOW; BONE PLATE; BONE STRESS; CALCULATION; CONTROLLED STUDY; FEMALE; FEMUR; FEMUR CONDYLE; FLUORESCENCE; FLUORESCENT MICROSPHERE; HUMERUS; MEASUREMENT; MENISCECTOMY; NONHUMAN; PRIORITY JOURNAL; RABBIT; RELIABILITY; TECHNIQUE; TIBIA; VALIDATION PROCESS;

ANIMALS; BONE AND BONES; FEMALE; FEMUR; FLUORESCENT DYES; HUMERUS; LONGITUDINAL STUDIES; MENISCI, TIBIAL; MICROSPHERES; ORTHOPEDIC PROCEDURES; OSTEOARTHRITIS; POSTOPERATIVE PERIOD; PULMONARY CIRCULATION; RABBITS; REGIONAL BLOOD FLOW; RENAL CIRCULATION; TIME FACTORS;

EID: 2342486106     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/japplphysiol.00904.2003     Document Type: Article

References (31)

1. Anetzberger H, Metak G, Scherer MA, Putz R, and Müller-Gerbl M. Anpassung der subchondralen Knochenplatte nach Meniskektomie als Folge einer Änderung der Spannungsverteilung. Osteologie 4: 224-232, 1995.
2. Anetzberger H, Thein E, Becker M, Walli AK, and Messmer K. Validity of fluorescent microspheres method for bone blood flow measurement during intentional arterial hypotension. J Appl Physiol 95: 1153-1158, 2003.
3. Anetzberger H, Thein E, Walli AK, and Messmer K. Determination of regional bone blood flow by means of fluorescent microspheres using an automated sample processing procedure. Eur Surg Res 35: 337-345, 2003.
4. Bland JM and Altman DG. Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1: 307-310, 1986.
5. Bünger C, Bulow J, Hjermind J, and Harving S. Hemodynamics of the juvenile dog knee in relation to increased venous outlet resistance. Pflügers Arch 399: 129-133, 1983.
6. Colombo C, Butler M, O'Byrne E, Hickman L, Swartzendruber D, Selwyn M, and Steinetz B. A new model of osteoarthritis in rabbits. I. Development of knee joint pathology following lateral meniscectomy and section of the fibular collateral and sesamoid ligaments. Arthritis Rheum 26: 875-886, 1983.
7. Duncan CP and Shim SS. The autonomic nerve supply of bone. An experimental study of the intraosseous adrenergic nervi vasorum in the rabbit. J Bone Joint Surg Br 59: 323-330, 1977.
8. Gao J and Messner K. Natural healing of anterior and posterior attachments of the rabbit meniscus. Clin Orthop 328: 276-284, 1996.
9. Gregg PJ and Walder DN. Regional distribution of circulating microspheres in the femur of the rabbit. J Bone Joint Surg Br 62: 222-226, 1980.
10. Gross PM, Heistad DD, and Marcus ML. Neurohumoral regulation of blood flow to bones and marrow. Am J Physiol Heart Circ Physiol 237: H440-H448, 1979.
11. Gross TS, Damji AA, Judex S, Bray RC, and Zernicke RF. Bone hyperemia precedes disuse-induced intracortical bone resorption. J Appl Physiol 86: 230-235, 1999.
12. Imhof H, Breitenseher M, Kainberger F, and Trattnig S. Degenerative joint disease: cartilage or vascular disease? Skeletal Radiol 26: 398-403, 1997.
13. Jones LC, Niv Al, Davis RF, and Hungerford DS. Bone blood flow in the femora of anesthetized and conscious dogs in a chronic preparation, using the radioactive tracer microsphere method. Clin Orthop 170: 286-295, 1982.
14. Jong De MK, Van den Bos GC, and Elzinga G. Changes of microsphere density with time in myocardial infarcts in dogs. Bibl Anat 15: 147-150, 1977.
15. Kaihara S, Van Heerden PD, Migita T, and Wagner HNJ. Measurement of distribution of cardiac output. J Appl Physiol 25: 696-700, 1968.
16. Korkala O, Karaharju E, Gronblad M, and Aalto K. Articular cartilage after meniscectomy. Rabbit knees studied with the scanning electron microscope. Acta Orthop Scand 55: 273-277, 1984.
17. Layton MW, Goldstein SA, Goulet RW, Feldkamp LA, Kubinski DJ, and Bole GG. Examination of subchondral bone architecture in experimental osteoarthritis by microscopic computed axial tomography. Arthritis Rheum 31: 1400-1405, 1988.
18. McDevitt CA and Miller RR. Biochemistry, cell biology, and immunology of osteoarthritis. Curr Opin Rheumatol 1: 303-314, 1989.
19. McGrory BJ, Moran CG, Bronk J, Weaver AL, and Wood MB. Canine bone blood flow measurements using serial microsphere injections. Clin Orthop 303: 264-279, 1994.
20. Messner K, Fahlgren A, Ross I, and Andersson B. Simultaneous changes in bone mineral density and articular cartilage in a rabbit meniscectomy model of knee osteoarthrosis. Osteoarthritis Cartilage 8: 197-206, 2000.
21. Norrdin RW, Kawcak CE, Capwell BA, and McIlwraith CW. Subchondral bone failure in an equine model of overload arthrosis. Bone 22: 133-139, 1998.
22. Raab S, Thein E, Harris AG, and Messmer K. A new sample-processing unit for the fluorescent microsphere method. Am J Physiol Heart Circ Physiol 276: H1801-H1806, 1999.
23. Radin EL, Martin RB, Burr DB, Caterson B, Boyd RD, and Goodwin C. Effects of mechanical loading on the tissues of the rabbit knee. J Orthop Res 2: 221-234, 1984.
24. Radin EL and Rose RM. Role of subchondral bone in the initiation and progression of cartilage damage. Clin Orthop 213: 34-40, 1986.
25. Schimmel C, Frazer D, Huckins SR, and Glenny RW. Validation of automated spectrofluroimetry for measurement of regional organ perfusion using fluorescent microspheres. Comput Methods Programs Biomed 62: 115-125, 2000.
26. Shymkiw RC, Bray RC, Boyd SK, Kantzas A, and Zernicke RF. Physiological and mechanical adaptation of periarticular cancellous bone after joint ligament injury. J Appl Physiol 90: 1083-1087, 2001.
27. Sommerlath K and Gillquist J. The effect of a meniscal prosthesis on knee biomechanics and cartilage. An experimental study in rabbits. Am J Sports Med 20: 73-81, 1992.
28. Thein E, Raab S, Harris AG, and Messmer K. Automation of the use of fluorescent microspheres for the determination of blood flow. Comput Methods Programs Biomed 61: 11-21, 2000.
29. Van Oosterhout MF, Prinzen FW, Sakurada S, Glenny RW, and Hales JR. Fluorescent microspheres are superior to radioactive microspheres in chronic blood flow measurements. Am J Physiol Heart Circ Physiol 275: H110-H115, 1998.
30. Wei L, de Bri E, Lundberg A, and Svensson O. Mechanical load and primary guinea pig osteoarthrosis. Acta Orthop Scand 69: 351-357, 1998.
31. Will-Hofmann H. Regenerative processes of the internal structures of the knee joint following meniscectomy. Experimental study of the knee joint of the rabbit. Z Orthop Ihre Grenzgeb 123: 957-961, 1985.