Ketamine for paediatric sedation/analgesia in the emergency department

Emergency Medicine Journal

Volumn 21, Issue 3, 2004, Pages 275-280

  Howes, Marten C ^a  

^a ROYAL PRESTON HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

KETAMINE; MIDAZOLAM; OXYGEN; SEDATIVE AGENT;

ANALGESIA; APNEA; ATAXIA; CHILD; CHILDHOOD INJURY; DISTRESS SYNDROME; DRUG MECHANISM; DYSPHORIA; EMERGENCY WARD; FEAR; FLUSHING; GENERAL ANESTHESIA; HALLUCINATION; HUMAN; LARYNX SPASM; LIMB MOVEMENT; MEDICAL INSTRUMENTATION; MOTOR DYSFUNCTION; MYOCLONUS; NYSTAGMUS; OPISTHOTONUS; PAIN; PARENTAL BEHAVIOR; PLAY THERAPY; PRACTICE GUIDELINE; PRIORITY JOURNAL; RASH; RESPIRATORY TRACT DISEASE; REVIEW; SEDATION; SIDE EFFECT; STAFF; UNITED KINGDOM; VOMITING;

ANALGESIA; ANALGESICS; CHILD; CONSCIOUS SEDATION; EMERGENCY SERVICE, HOSPITAL; HUMANS; KETAMINE; WOUNDS AND INJURIES;

EID: 2342461101     PISSN: 14720205     EISSN: None     Source Type: Journal    
DOI: 10.1136/emj.2003.005769     Document Type: Review

References (72)

1. Kennedy RM. The "ouchless emergency department" getting closer: advances in decreasing distress during painful procedures in the emergency department. Pediatr Clin North Am 1999;46:1215-47.
2. Kleinknecht RA. Acquisition of blood, injury, and needle fears and phobias. Behav Res Ther 1994;32:817-23.
3. Trigwell PJ. Iatrogenic needle phobia. [Letter]. Br Dent J 1993;174:158.
4. Maurice SC, O'Donnell JJ, Beattie TF. Emergency analgesia in the paediatric population. Part II pharmacological methods of pain relief. Emerg Med J 2002;19:101-5.
5. O'Donnell JJ, Maurice SC, Beattie TF. Emergency analgesia in the paediatric population. Part III non-pharmacological measures of pain relief and anxiolysis. Emerg Med J 2002;19:195-7.
6. Doyle E. Emergency analgesia in the paediatric population. Part IV paediatric sedation in the emergency department: pros and cons. Emerg Med J 2002;19:284-7.
7. Blackburn P, Vissers R. Pharmacology of emergency department pain management and conscious dissociation. Emerg Med Clin North Am 2000;18:803-27.
8. Epstein FB. Ketamine dissociative sedation in pediatric emergency medicine practice. Am J Emerg Med 1993;11:180-2.
9. Sobel RM, Morgan BW, Murhy M. Ketamine in the ED: medical politics versus patient care. Am J Emerg Med 1999;17:722-5.
10. Green SM, Johnson NE. Ketamine sedation for pediatric procedures: Part 2, review and implications. Ann Emerg Med 1990;19:1033-46.
11. Heckman JD. The use of dedamine sedation. J Bone Joint Surg [Am] 2000;82-A:911.
12. Dachs RJ, Innes GM. Intravenous ketamine sedation of pediatric patients in the emergency department. Ann Emerg Med 1997;29:146-50.
13. Ducharme J. Ketamine: Do what is right for the patient. Emerg Med 2002;13:7-8.
14. Sacchetti A. Pediatric sedation and analgesia. Emerg Med 1995;27:67-87.
15. McCarty EC, Mencio GA, Walker LA, et al. Ketamine sedation for the reduction of children's fractures in the emergency department. J Bone Joint Surg [Am] 2000;82-A:912-18.
16. Green SM, Rothrock SG, Lynch EL, et al. Intramuscular ketamine for pediatric sedation in the emergency department: safety profile in 1,022 cases. Ann Emerg Med 1998;31:688-97.
17. Green SM, Krauss B. The semantics of ketamine. Ann Emerg Med 2000;36:480-2.
18. Adams HA, Hemplemann G. Twenty years of ketamine - a retrospective view. Anaesthetist 1990;39:71-6.
19. McGlone RG, Ranasinghe S, Durham S. An alternative to "Brutacaine": a comparison of low dose intramuscular ketamine with intranasal midazolam before suturing. J Accid Emerg Med 1998; 15:231-6.
20. McGlone R, Fleet T, Durham S, et al. A comparison of intramuscular ketamine with high dose intramuscular midazolam with and without intranasal flumazenil in children before suturing. Emerg Med J 2001;18:34-8.
21. Holloway VJ, Husain HM, Saetta JP, et al. Accident and emergency department led implementation of ketamine sedation in paediatric practice and parental response. J Accid Emerg Med 2000;17:25-8.
22. Ilkhanipour K, Juels CR, Langdorf MI. Pediatric pain control and conscious sedation: a survey of emergency medicine residents. Acad Emerg Med 1995;1:368-72.
23. Hostetler MA, Auinger P, Szilagyi PG. Parenteral analgesic and sedative use among ED patients in the United States: combined results from the National Hospital Ambulatory Medical Care Survey (NHAMCS) 1992-1997. Am J Emerg Med 2002;20:83-7 and erratum in Am J Emerg Med 2002;20:496.
24. Priestly SJ, Taylor J, McAdam CM, et al. Ketamine sedation for children in the emergency department. Emerg Med 2001;13:82-90.
25. Everitt I, Younge P, Barnett P. Paediatric sedation in emergency departments: What is our practice? Emerg Med 2002;14:62-6.
26. Ng KC, Ang SY. Sedation with ketamine for paediatric procedures in the emergency department - a review of 500 cases. Singapore Med J 2002;42:300-4.
27. American College of Emergency Physicians. Clinical policy for procedural sedation and analgesia in the emergency department. Ann Emerg Med 1998;31:663-77.
28. Australasian College of Emergency Medicine. Policy document - use of intravenous sedation for procedures in the emergency department. http://www.acem.org.au/open/documents/sedation.htm (accessed Jan 2003).
29. Scottish Intercollegiate Guidelines Network. http://www.sign.ac.uk/ (accessed Jan 2003).
30. White PF, Way WL, Trevor AJ. Ketamine - its pharmacology and therapeutic uses. Anesthesiology 1982;56:119-36.
31. Reich DL, Silvay G. Ketamine: an update on the first twenty-five years of clinical experience. Can J Anaesth 1989;36:186-97.
32. Sadove MS, Shulman M, Hatano S, et al. Analgesic effects of ketamine in subdissociative doses. Anesth Analg 1971;50:452-7.
33. Komatsu T, Singh PK, Kimura T, et al. Differential effects of ketamine and midazolam on heart rate. Can J Anaesth 1995;42:1003-9.
34. Park GR, Manara AR, Medel L, et al. Ketamine infusion. Its use as a sedative, inotrope and bronchodilator in a critically ill patient. Anaesthesia 1987;42:980-3.
35. L'Hommedieu CS. The use of ketamine for the emergency department intubation of patients with status asthmaticus. Ann Emerg Med 1987;16:568-71.
36. Strube PJ, Hallam PL. Ketamine by continuous infusion in status asthmaticus. Anaesthesia 1986;41:1017-19.
37. Youssef-Ahmed MZ, Silver P, Nimkoff L, et al. Continuous infusion of ketamine in mechanically ventilated children with refractory bronchospasm. Intensive Care Medicine 1996;22:972-6.
38. Green SM, Nakamura R, Johnson NE. Ketamine sedation for pediatric procedures: Part 1, a prospective series. Ann Emerg Med 1990;19:1024-32.
39. Sussman DR. A comparative evaluation of ketamine anesthesia in children and adults. Anesthesiology 1974;40:459-64.
40. McGlone RG, Howes MC, Joshi M. The Lancaster experience of 2.0 to 2.5 mg/kg intramuscular ketamine for paediatric sedation: 501 cases and analysis. Emerg Med J 2004;21:290-5.
41. Smith JA, Santer LJ. Respiratory arrest following intramuscular ketamine injection in a 4-year-old child. Ann Emerg Med 1993;22:613-15.
42. Greenhalgh T. How to read a paper: the Medline database. BMJ 1997;315:180-3.
43. Younge PA, Kendall JM. Sedation for children requiring wound repair: a randomised controlled double blind comparison of oral midazolam and oral ketamine. Emerg Med J 2001;18:30-3.
44. Acworth JP, Purdie K, Clark RC. Intravenous ketamine plus midazolam is superior to intranasal midazolam for emergency paediatric procedural sedation. Emerg Med J 2001;18:39-45.
45. Green SM, Kuppermann N, Rothrock SG, et al. Predictors of adverse events with intramuscular ketamine sedation in children. Ann Emerg Med 2000;35:35-42.
46. Kapklein MJ, Slonim AD. Ketamine vs. Propofol: How safe is safe enough. Crit Care Med 2002;30:1384-6.
47. Green SM, Clem KJ, Rothrock SG. Ketamine safety profile in the developing world:survey of practioners. Acad Emerg Med 1996;3:598-604.
48. Ketchman DW. Where there is no anesthesiologist: the many uses of ketamine in the developing world. Trop Doct 1990;20:163-6.
49. Pederson L, Benumhof J. Incidence and magnitude of hypoxaemia with ketamine in a rural African hospital. Anaesthesia 1993;48:67-9.
50. Gofrit ON, Leibovici D, Shemer J, et al. Ketamine in the field: the use of ketamine for induction of anaesthesia before intubation in injured patients in the field. Injury 1997;28:41-3.
51. Tighe SQ, Rudland SV. Anesthesia in northern Iraq: an audit from a field hospital. Mil Med 1994;159:86-90.
52. Cottingham R, Thomson K. Use of ketamine in prolonged entrapment. J Accid Emerg Med 1994;11:189-91.
53. Trouwborst A, Weber Bk, Dufour D. Medical statistics of battlefield casualties. Injury 1987;18:96-9.
54. Green SM, Clark R, Hostetler MA, et al. Inadvertent ketamine overdose in children: clinical manifestations and outcome. Ann Emerg Med 1999;34:492-7.
55. Green SM, Klooster M, Harris T, et al. Ketamine sedation for pediatric gastroenterology procedures. J Pediatr Gastroenterol Nutr 2001;32:26-33.
56. Sherwin TS, Green SM, Khan A, et al. Does adjuctive midazolam reduce recovery agitation after ketamine sedation for pediatric procedures? A randomised, double-blind, placebo-controlled trial. Ann Emerg Med 2000;35:229-38.
57. Wathen JE, Roback MG, MacKenzie T, et al. Does midazolam alter the clinical effects of intravenous ketamine sedation in children? A double-blind, randomised, controlled emergency department trial. Ann Emerg Med 2000;36:579-88.
58. Carley S, Martin B. Midazolam and emergence phenomena in children. Emerg Med J 2001;18:273-4.
59. Paxton D. Treating postoperative nausea in children. Hospital Update 1996:428-30.3.
60. Green SM, Krauss B. Pulmonary aspiration risk during emergency department procedural sedation - an examination of the role of fasting and sedation depth. Acad Emerg Med 2002;9:35-42.
61. Green SM, Rothrock SG, Harris T, et al. Intravenous ketamine for pediatric sedation in the emergency department: safety profile with 156 cases. Acad Emerg Med 1998;5:971-6.
62. Peña BMG, Krauss B. Adverse events of percedural sedation and analgesia in a pediatric emergency department. Ann Emerg Med 1999;34:483-91.
63. Glickman A. Ketamine: the dissociative anesthetic and the development of a policy for its safe administration in the pediatric emergency department. J Emerg Nurs 1995;21:116-15.
64. Kennedy RM, Porter F, Miller JP, et al. Comparison of fentanyl/midazolam with ketamine/midazolam for pediatric orthopedic emergencies. Pediatrics 1998;102):956-63.
65. Murphy M. Sedation. Ann Emerg Med 1996;27:461-3.
66. Green SM, Hummel CB, Wittlake WA, et al. What is the optimal dose of intramuscular ketamine for pediatric sedation? Acad Emerg Med 1999;6:21-6.
67. Chudnofsky CR, Weber JE, Stoyanoff PJ, et al. A combination of midazolam and ketamine for procedural sedation and analgesia in adult emergency department patients. Acad Emerg Med 2000;7:278-81.
68. UK Academy of Medical Royal Colleges and their Faculties. Implementing and ensuring safe sedation practice for healthcare procedures in adults. Report of an Intercollegiate Working Party chaired by the Royal College of Anaesthetists. London: RCA, 2001.
69. Dental Teachers Sedation Group. Standards for conscious sedation in dentistry. Report of an Independent Expert Working Group. London: Dental Teachers Sedation Group, 2000. http://www.dstg.co.uk/oct2000sicsfd/oct2000.htm (accessed Jan 2003).
70. Roscow C, Manberg PJ. Bispectral index monitoring. Anesthesiol Clin North Am 1998;2:89-107.
71. Royal College of Anaesthetists. Guidance on the provision of paediatric anaesthetic services. London: RCA, 2001. htpp: //www.rcoa.ac.uk/dload/paediatric%20services.pdf (accessed Jan 2003).
72. Green SM. Modern anesthesiologists receive limited training with ketamine - implications for emergency medicine.[Letter]. Acad Emerg Med 2000;7:839-41.