An alternative to "brutacaine": A comparison of low dose intramuscular ketamine with intranasal midazolam in children before suturing

Emergency Medicine Journal

Volumn 15, Issue 4, 1998, Pages 231-236

  McGlone, R G ^a   Ranasinghe, S ^a   Durham, S ^a  

^a ROYAL LANCASTER INFIRMARY   (United Kingdom)

Author keywords

Children; Ketamine; Midazolam; Suturing

Indexed keywords

KETAMINE; MIDAZOLAM;

AFTERDISCHARGE; ANESTHESIA; ARTICLE; CHILD; CHILD BEHAVIOR; CLINICAL TRIAL; CONTROLLED STUDY; CRYING; GAIT DISORDER; HUMAN; INTRAMUSCULAR DRUG ADMINISTRATION; INTRANASAL DRUG ADMINISTRATION; LENGTH OF STAY; MAJOR CLINICAL STUDY; OXYGEN SATURATION; SEDATION; SUTURING METHOD; VOMITING; WOUND CLOSURE;

ADMINISTRATION, INTRANASAL; ANESTHETICS, DISSOCIATIVE; ANTI-ANXIETY AGENTS; CHILD; CHILD, PRESCHOOL; CONSCIOUS SEDATION; FEMALE; HUMANS; INFANT; INJECTIONS, INTRAMUSCULAR; KETAMINE; MALE; MIDAZOLAM; QUESTIONNAIRES; STATISTICS, NONPARAMETRIC; SUTURES; WOUNDS AND INJURIES;

EID: 2742536886     PISSN: 13510622     EISSN: None     Source Type: Journal    
DOI: 10.1136/emj.15.4.231     Document Type: Review

References (35)

1. Green G, Nakamura R, Johnson E. Ketamine sedation for paediatric procedures; part I, a prospective series. Ann Emerg Med 1990;19:1024-32.
2. Green G, Johnson E. Ketamine sedation for paediatric procedures: part 2, review and implications. Ann Emerg Med 1990;19 1033-46.
3. Epstein F Ketamine dissociative sedation in paediatric emergency medical practice. Am J Emerg Med 1993;11: 180-2
4. Theroux M, West D. Efficacy of intranasal midazolam in facilitating suturing of lacerations in preschool children in the emergency department. Pediatrics 1993;91:624-7.
5. Pruitt J, Goldwasser M. Intramuscular ketamine, midazolam, and glycopyrrolate for paediatric sedation in the emergency department. J Oral Maxillofac Surg 1995;53: 13-17.
6. Yealy D, Ellis J. Intranasal midazolam as a sedative for children during laceration repair Am J Emerg Med 1992;10: 584-7.
7. Qureshi F, Mellis P. Efficacy of oral ketamine for providing sedation and to children requiring laceration repair. Pediatr Emerg Care 1995;11:93-7
8. Connors K, Terndrup T. Nasal versus, oral midazolam. for sedation of anxious children undergoing laceration repair. Ann Emerg Med 1994;24:1074-9.
9. Louon A, Reddy V. Nasal midazolam and ketamine for paediatric sedation during computerised tomography. Acta Anaesthesiol Scand 1994,38.259-61.
10. Abrams R, Morrison J Safety and effectiveness of intranasal administration of sedative medications (ketamine, midazolam or sufentanil) for urgent brief paediatric dental procedures. Anaesthesia Progress 1993;40:63-6.
11. Huwitz G, DeVore D. Decreased doses of ketamine hydrochloride in children: a triple blind study. Journal of the Baltimore College of Dental Surgery 1975,30:28-34.
12. Rey E, Delaunay L. Pharmacokinetics of midazolam in children: comparative study of intranasal and intravenous administration. Eur J Clin Pharmacol 1991,41:355-7.
13. Walker J. The use of oral midazolam in A&E to reduce anxiety in children. Accid Emerg Nursing 1996;4 110-13.
14. Taiwo B, Flowers M, Zoltie N Reducing children's fear when undergoing painful procedures. Arch Emerg Med 1992;9:306-9.
15. Payne JG, Mattheyse FJ. The pharmacokinetics of midazolam in paediatric patients Eur J Clin Pharmacol 1989:;37 267-72.
16. Karl H, Rosenberger J. Transmucosal administration of midazolam for premedication of pediatric patients. Anesthesiology 1993;78;885-91.
17. Taylor MB, Vine PR. Intramuscular midazolam premedication in young children. Anaesthesia 1986;41.21-6.
18. Greenberg RS, Maxwell LG. Preanaesthetic medication of children with midazolam using the Biojector jet injector. Anesthesiology 1995,83:264-9.
19. Bozkurt P, Kilic N. The effects of mtranasal midazolam on urodynamic studies in children. Br J Urol 1996;78:282-6.
20. Fosel T. Hack C, Knoll R. Nasal midazolam in children, plasma concentrations and the effect on respiration. Paediatr Anaesth 1995,5:347-53.
21. Malinovsky J, Lejus C, Servin F. Plasma concentrations of midazolam after IV, nasal or rectal administration in children. Br J Anaesth 1993;70:617-20.
22. Fraser G. Intranasal midazolam. Hospital Pharmacy 1992; 27:73-4.
23. Lugo R, Fishbein M. Complication of intranasal midazolam [letter]. Pediatrics 1993;92:638.
24. Cohen M, Gur E Intranasal administration of midazolam with a dinosaur toy [letter]. Plast Reconstr Surg 1995;95: 421-2
25. Sakane T. Direct drug transport from the rat nasal cavity to the cerebrospinal fluid: the relation to the dissociation of the drug. J Pharm Pharmacol 1994;46:378-9.
26. Twersky R, Hartung J. Midazolam enhances anterograde but not retrograde amnesia in paediatric patients. Anaesthesiology 1993,78.51-5.
27. Kupietzky A, Holan G. Intranasal midazolam better at effecting amnesia after sedation than oral hydroxyzine: a pilot study Pediatr Dent 1996;18:32-4.
28. Wallace S. Nasal benzodiazepines for management of acute childhood seizures? Lancet 1997;349:222.
29. Aldrete J, Russell L, Davis F. Intranasal administration of ketamine: possible applications Acta Anaesthiol Belg (Suppl) 1988,39:95-6
30. Dachs RJ, Innes GM. Intravenous ketamine sedation of paediatric patients in the emergency department. Ann Emerg Med 1997,29:146-50.
31. Parker RI, Mahan RA. Efficacy and safety of intravenous midazolam and ketamine as sedation for therapeutic and diagnostic procedures in children. Pediatrics 1997;99.427-31.
32. Smith J, Santer L. Respiratory arrest following intramuscular ketamine injection in a 4 year old child Ann Emerg Med 1993;22:613-15 [Letters 1993,23:139-40.]
33. Smith J, Santer L. Respiratory arrest following intramuscular ketamine injection in a 4 year old child Ann Emerg Med 1993;22:613-15 [Letters 1993,23:139-40.]
34. Duda J.The goods bad, and ugly: using ketamine for ED pediatric patients. J Emerg Nurs 1996,22:49-51
35. Glickman A. Ketamine: the dissociative anesthetic and the development of a policy for its safe administration in the pediatric emergency department. J Emerg Nurs 1995;21: 116-24.