A new model for determining the influence of age and sex on functional recovery following hypoxic-ischemic brain damage

Developmental Neuroscience

Volumn 27, Issue 2-4, 2005, Pages 112-120

  Yager, Jerome Y ^a,b,d   Wright, Sandra ^a,c   Armstrong, Edward A ^a,b   Jahraus, Cleo M ^a   Saucier, Deborah M ^a  

^a UNIVERSITY OF SASKATCHEWAN   (Canada)

^b UNIVERSITY OF ALBERTA   (Canada)

^c MEMORIAL UNIVERSITY OF NEWFOUNDLAND   (Canada)

^d STOLLERY CHILDREN S HOSPITAL   (Canada)

Author keywords

Brain damage; Gender differences; Hypoxia ischemia; Newborn brain

Indexed keywords

ENDOTHELIN 1;

AGE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIOR; BRAIN CORTEX; BRAIN HYPOXIA; BRAIN INJURY; BRAIN ISCHEMIA; BRAIN REGION; CAUDATE NUCLEUS; CONTROLLED STUDY; CONVALESCENCE; DISEASE MODEL; FEMALE; GROUPS BY AGE; HIPPOCAMPUS; MALE; MIDDLE CEREBRAL ARTERY; NEUROPATHOLOGY; NEWBORN; NEWBORN PERIOD; NONHUMAN; PRIORITY JOURNAL; RAT; RODENT; SEX DIFFERENCE; STROKE; THALAMUS;

AGE FACTORS; ANIMALS; BRAIN; DISEASE MODELS, ANIMAL; FEMALE; HYPOXIA-ISCHEMIA, BRAIN; MALE; RATS; RATS, WISTAR; RECOVERY OF FUNCTION; SEX FACTORS;

EID: 23244462291     PISSN: 03785866     EISSN: None     Source Type: Journal    
DOI: 10.1159/000085982     Document Type: Article

References (49)

1. Bogousslavsky J, Pierre P: Ischemic stroke in patients under age 45; in Barnett HJM, Hachinski V (eds): Neurologic Clinics: Cerebral Ischemia: Treatment and Prevention. Philadelphia, WB Saunders Co, 1992, pp 113-124.
2. Bogousslavsky J, Van Melle G, Regli F: The Lausanne Stroke Registry: Analysis of 1,000 consecutive patients with first stroke. Stroke 1988;19:1083-1092.
3. Schoenberg BS, Mellinger JF, Schoenberg DG: Cerebrovascular disease in infants and children: A study of incidence, clinical features and survival. Neurology 1978;28:763-768.
4. deVeber G: Stroke and the child's brain: An overview of epidemiology, syndromes and risk factors. Curr Opin Neurol 2002;15:133-138.
5. United States Department of Health, Education, and Welfare: National Survey of Stroke. Washington, National Institutes of Health, publication No 80-2069, 1980.
6. Auer RN: Excitotoxic mechanisms, age-related susceptibility to brain damage in ischemia, hypoglycemia and toxic mussel poisoning. Neurotoxicology 1991;12:541-546.
7. Duffy TE, Kohle SJ, Vannucci RC: Carbohydrate and energy metabolism in perinatal rat brain: Relation to survival in anoxia. J Neurochem 1975;24:271-276.
8. Fazekas J, Alexander AD, Himich HE: Tolerance of the newborn to anoxia. Am J Physiol 1941;134:281-287.
9. Glass H, Snyder FF, Webster E: The rate of decline in resistance to anoxia for rabbits, dogs and guinea pigs from the onset of viability to adult life. Am J Physiol 1944;140:609-615.
10. Jilek L, Fischer J, Virulich L, Trojan S: The reaction of the brain to stagnant hypoxia and anoxia during ontogeny. Prog Brain Res 1964;9:113-131.
11. Towfighi JC, Mauger D, Vannucci RC, Vannucci SJ: Influence of age on the cerebral lesions in an immature rat model of cerebral HI: A light microscope study. Brain Res Dev Brain Res 1997;100:149-160.
12. Muramatsu K, Fukuda A, Togari H, Nishino H: Topography of hypoxic injury proved by argyrophilia in postnatal rat brain. Pediatr Neurol 1997;16:105-113.
13. McDonald JW, Silverstein FS, Johnston MV: Neurotoxicity of N-methyl-D-aspartate is markedly enhanced in developing rat central nervous system. Brain Res 1988;459:200-203.
14. Ikonomidou C, Mosinger JL, Salles KS, Labruyere J, Olney JW: Sensitivity of the developing rat brain to hypobaric/ischemic damage parallels sensitivity to N-methyl-aspartate neurotoxicity. J Neurosci 1989;9:2809-2818.
15. Yager JY, Shuaib A, Thornhill J: The effect of age on susceptibility to brain damage in a model of global hemispheric hypoxia-ischemia. Brain Res Dev Brain Res 1996;93:143-154.
16. Sharkey J, Butcher SP: Characterisation of an experimental model of stroke produced by intracerebral microinjection of endothelin-1 adjacent to the rat middle cerebral artery. J Neurosci Methods 1995;60:125-131.
17. Henshall DC, Butcher SP, Sharkey J: A rat model of endothelin-3-induced middle cerebral artery occlusion with controlled reperfusion. Brain Res 1999;843:105-111.
18. Sharkey J, Ritchie IM, Kelly PA: Perivascular microapplication of endothelin-1: A new model of focal cerebral ischaemia in the rat. J Cereb Blood Flow Metab 1993;13:865-871.
19. Hagberg H, Ichord R, Palmer C, Yager JY, Vannucci SJ: Animal models of developmental brain injury: Relevance to human disease. A summary of the panel discussion from the Third Hershey Conference on Developmental Cerebral Blood Flow and Metabolism. Dev Neurosci 2002;24:364-366.
20. McIlwain H, Bachelard HS: Chemical and Enzymatic Make-Up of the Brain during Development and Ageing. Biochemistry and the Central Nervous System. Baltimore, Williams and Wilkins, 1971, pp 371-412.
21. Pettigrew JW, Panchalingam K, Withers G, et al: Changes in brain energy and phospholipid metabolism during development and aging in the Fischer 344 rat. J Neuropathol Exp Neurol 1990;49:237-249.
22. Yager JY: Animal models of hypoxic-ischemic brain damage in the newborn. Semin Pediatr Neurol 2004;11:31-46.
23. Wirrell EC, Armstrong EA, Osman LD, Yager JY: Prolonged seizures exacerbate perinatal hypoxic-ischemic brain damage. Pediatr Res 2001;50:445-454.
24. Sharkey J, Butcher SP, Kelly JS: Endothelin-1 induced middle cerebral artery occlusion: Pathological consequences and neuroprotective effects of MK801. J Auton Nerv Syst 1994;49(suppl):S177-S185.
25. Kugler C, Altenhoner T, Lochner P, Ferbert A: Does age influence early recovery from ischemic stroke? A study from the Hessian Stroke Data Bank. J Neurol 2003;250:676-681.
26. Bagg S, Pombo AP, Hopman W: Effect of age on functional outcomes after stroke rehabilitation. Stroke 2002;33:179-185.
27. Kalra L: Does age affect benefits of stroke unit rehabilitation? Stroke 1994;25:346-351.
28. Yager JY, Shuaib A, Thornhill J: The effect of age on susceptibility to brain damage in a model of global hemispheric hypoxia-ischemia. Brain Res Dev Brain Res 1996;93:143-154.
29. Kolb B: Overview of cortical plasticity and recovery from brain injury. Phys Med Rehabil Clin N Am 2003;14:S7-25, viii.
30. Kolb B, Cioe J, Whishaw IQ: Is there an optimal age for recovery from motor cortex lesions? 1. Behavioral and anatomical sequelae of bilateral motor cortex lesions in rats on postnatal days 1, 10, and in adulthood. Brain Res 2000;882:62-74.
31. Kolb B, Cioe J, Whishaw IQ: Is there an optimal age for recovery from motor cortex lesions? 2. Behavioural and anatomical consequences of unilateral motor cortex lesions in perinatal, infant, and adult rats. Restor Neurol Neurosci 2000;17:61-70.
32. Hallett M: Plasticity of the human motor cortex and recovery from stroke. Brain Res Brain Res Rev 2001;36:169-174.
33. Ikonomidou C, Bosch F, Miksa M, et al: Blockade of NMDA receptors and apoptotic neurodegeneration in the developing brain. Science 1999;283:70-74.
34. Olney JW, Young C, Wozniak DF, Jevtovic-Todorovic V, Ikonomidou C: Do pediatric drugs cause developing neurons to commit suicide? Trends Pharmacol Sci 2004;25:135-139.
35. 2+ channels. J Hypertens Suppl 1988;6:S188-S191.
36. Fuxe K, Kurosawa N, Cintra A, et al: Involvement of local ischemia in endothelin-1 induced lesions of the neostriatum of the anaesthetized rat. Exp Brain Res 1992;88:131-139.
37. Fuxe K, Bjelke B, Andbjer B, Grahn H, Rimondini R, Agnati LF: Endothelin-1 induced lesions of the frontoparietal cortex of the rat. A possible model of focal cortical ischemia. Neuroreport 1997;8:2623-2629.
38. Park L, Thornhill J: Hypoxic modulation of striatal lesions induced by administration of endothelin-1. Brain Res 2000;883:51-59.
39. Rice JE 3rd, Vannucci RC, Brierley JB: The influence of immaturity on hypoxic-ischemic brain damage in the rat. Ann Neurol 1981;9:131-141.
40. Takaba H, Fukuda K, Yao H: Substrain differences, gender, and age of spontaneously hypertensive rats critically determine infarct size produced by distal middle cerebral artery occlusion. Cell Mol Neurobiol 2004;24:589-598.
41. Schwartz PH, Massarweh WF, Vinters HV, Wasterlain CG: A rat model of severe neonatal hypoxic-ischemic brain injury. Stroke 1992;23:539-546.
42. McCullough LD, Hurn PD: Estrogen and ischemic neuroprotection: An integrated view. Trends Endocrinol Metab 2003;14:228-235.
43. Hurn PD, Macrae IM: Estrogen as a neuroprotectant in stroke. J Cereb Blood Flow Metab 2000;20:631-652.
44. Alkayed NJ, Harukuni I, Kimes AS, London ED, Traystman RJ, Hurn PD: Gender-linked brain injury in experimental stroke. Stroke 1998;29:159-166.
45. Hurn PD, Brass LM: Estrogen and stroke: A balanced analysis. Stroke 2003;34:338-341.
46. Simpkins JW, Yang SH, Liu R, et al: Estrogen-like compounds for ischemic neuroprotection. Stroke 2004;35:2648-2651.
47. Rothwell PM, Slattery J, Warlow CP: A systematic review of the risks of stroke and death due to endarterectomy for symptomatic carotid stenosis. Stroke 1996;27:260-265.
48. Rothwell PM, Slattery J, Warlow CP: A systematic comparison of the risks of stroke and death due to carotid endarterectomy for symptomatic and asymptomatic stenosis. Stroke 1996;27:266-269.
49. Sarac TP, Hertzer NR, Mascha EJ, et al: Gender as a primary predictor of outcome after carotid endarterectomy. J Vasc Surg 2002;35:748-753.