Abdominal adiposity assessed by dual energy x-ray absorptiometry provides a sex-independent predictor of insulin sensitivity in older adults

Journals of Gerontology - Series A Biological Sciences and Medical Sciences

Volumn 60, Issue 7, 2005, Pages 872-877

  Lee, Cathy C ^a,b   Glickman, Scott G ^a   Dengel, Donald R ^a   Brown, Michael D ^a   Supiano, Mark A ^a  

^a UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^b VA ANN ARBOR HEALTHCARE SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; INSULIN;

ABDOMEN; ADIPOSE TISSUE; ADULT; AGED; AGING; ANTHROPOMETRIC PARAMETERS; ARTICLE; BODY FAT; BODY MASS; DUAL ENERGY X RAY ABSORPTIOMETRY; FEMALE; HUMAN; INSULIN SENSITIVITY; MALE; METABOLIC PARAMETERS; NORMAL HUMAN; PREDICTION; PRIORITY JOURNAL; WAIST CIRCUMFERENCE; WAIST HIP RATIO;

EID: 23244439256     PISSN: 10795006     EISSN: None     Source Type: Journal    
DOI: 10.1093/gerona/60.7.872     Document Type: Article

References (35)

1. Shimokata H, Tobin JD, Muller DC, Elahi D, Coon PJ, Andres R. Studies In the distribution of body fat: I. Effects of age, sex, and obesity. J Gerontol. 1989;44:66-73.
2. Kohrt WM. Abdominal obesity and associated cardiovascular comorbidities in the elderly. Coron Artery Dis. 1998;9:489-494.
3. Meyers DA, Goldberg AP, Bleecker ML, Coon PJ, Drinkwater DT, Bleecker ER. Relationship of obesity and physical fitness to cardiopulmonary and metabolic function in healthy older men. J Gerontol. 1991;46:M57-M65.
4. Bonora E, Del Prato S, Bonadonna RC, et al. Total body fat content and fat topography are associated differently with in vivo glucose metabolism in nonobese and obese nondiabetic women. Diabetes. 1992;41:1151-1159.
5. Guo SS, Zeller C, Chumlea WC, Siervogel RM. Aging, body composition, and lifestyle: the Fels Longitudinal Study. Am J Clin Nutr. 1999;70:405-411.
6. Laaksonen DE, Lakka HM, Niskanen LK, Kaplan GA, Salonen JT, Lakka TA. Metabolic Syndrome and development of diabetes mellitus: application and validation of recently suggested definitions of the Metabolic Syndrome in a prospective cohort study. Am J Epidemiol. 2002;156:1070-1077.
7. Yamashita S, Nakamura T, Shimomura I, et al. Insulin resistance and body fat distribution: contribution of visceral fat accumulation to the development of insulin resistance and atherosclerosis. Diabetes Care. 1996;19:287-291.
8. Cefalu WT, Wang ZQ, Werbel S, et al. Contribution of visceral fat mass to the insulin resistance of aging. Metabolism. 1995;44:954-959.
9. Carey DG, Jenkins AB, Campbell LV, Freund J, Chisholm DJ. Abdominal fat and insulin resistance in normal and overweight women: direct measurements reveal a strong relationship in subjects at both low and high risk of NIDDM. Diabetes. 1996;45:633-638.
10. Svendsen OL, Hassager C, Bergmann I, Christiansen C. Measurement of abdominal and intra-abdominal fat in postmenopausal women by dual energy x-ray absorptiometry and anthropometry: comparison with computerized tomography. Int J Obes. 1993;17:45-51.
11. Paradisi G, Smith L, Burtner C, et al. Dual energy x-ray absorptiometry assessment of fat mass distribution and its association with the insulin resistance syndrome. Diabetes Care. 1999;22:1310-1317.
12. Rissanen P, Hämäläinen P, Vanninen E, Tenbunen-Eskelinen M, Uusitupa M. Relationship of metabolic variables to abdominal adiposity measured by different anthropometric measurements and dual-energy x-ray absorptiometry in obese middle-aged women. Int J Obes. 1997; 21:367-371.
13. The Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. Report of the expert committee on the diagnosis and classification of diabetes mellitus. Diabetes Care. 1998;21 Supplement 1:S5-S19.
14. Bergman RN. Toward physiological understanding of glucose tolerance: minimal model approach. Diabetes. 1989;38:1512-1527.
15. 2, pH, and lactate from arterialized venous samples. J Appl Physiol. 1972;32:134-137.
16. Behnke AR, Wilmore JH. Evaluation and Regulation of Body Build and Composition. Englewood Cliffs, NJ: Prentice Hall; 1974.
17. Lohman TG, Roche AF, Martorell R, eds. Anthropometric Standardization Reference Manual. Champaign, IL: Human Kinetics; 1988.
18. Glickman SG, Marn CS, Supiano MA, Dengel DR. Validity and reliability of dual-energy X-ray absorptiometry for the assessment of abdominal adiposity. J Applied Physiol. 2004;97:509-514.
19. Van Pelt RE, Evans EM, Schechtman KB, Ehsani AA, Kohrt WM. Contributions of total and regional fat mass to risk for cardiovascular disease in older women. Am J Physiol Endocrinol Metab. 2002; 282:E1023-E1028.
20. Furler SM, Poynten AM, Kriketos AD, et al. Independent influences of central fat and skeletal muscle lipids on insulin sensitivity. Obes Res. 2001;9:535-543.
21. Rendell M, Hulthén UL, Törnquist C, Groop L, Mattiasson I. Relationship between abdominal fat compartments and glucose and lipid metabolism in early postmenopausal women. J Clin Endocrinol Metab. 2001;86:744-749.
22. Kelley DE, Thaete FL, Troost F, Huwe T, Goodpaster BH. Subdivisions of subcutaneous abdominal adipose tissue and insulin resistance. Am J Physiol Endocrinol Metab. 2000;278:E941-E948.
23. Sites CK, Calles-Escandón J, Brochu M, Butterfield M, Ashikaga T, Poehlman ET. Relation of regional fat distribution to insulin sensitivity in postmenopausal women. Fertil Steril. 2000;73:61-65.
24. Sparrow D, Borkan GA, Gerzof SG, Wisniewski C, Silbert CK. Relationship to fat distribution to glucose tolerance: results of computed tomography in male participants of the normative aging study. Diabetes. 1986;35:411-415.
25. Coon PJ, Rogus EM, Drinkwater D, Muller DC, Goldberg AP. Role of body fat distribution in the decline in insulin sensitivity and glucose tolerance with age. J Clin Endocrinol Metab. 1992;75:1125-1132.
26. Boden G, Chen X, DeSantis RA, Kendrick Z. Effects of age and body fat on insulin resistance in healthy men. Diabetes Care. 1993;16: 728-733.
27. Marcus MA, Murphy L, Pi-Sunyer FX, Albu JB. Insulin sensitivity and serum triglyceride level in obese white and black women: relationship to visceral and truncal subcutaneous fat. Metabolism. 1999;48: 194-199.
28. Goodpaster BH, Thaete FL, Simoneau JA, Kelley DE. Subcutaneous abdominal fat and thigh muscle composition predict insulin sensitivity independently of visceral fat. Diabetes. 1997;46:1579-1585.
29. Abate N, Garg A, Peshock RM, Stray-Gundersen J, Grundy SM. Relationships of generalized and regional adiposity to insulin sensitivity in men. J Clin Invest. 1995;96:88-98.
30. Pouliot MC, Després JP, Lemieux S, et al. Waist circumference and abdominal sagittal diameter: best simple anthropometric indexes of abdominal visceral adipose tissue accumulation and related cardiovascular risk in men and women. Am J Cardiol. 1994;73:460-468.
31. Kohrt WM, Kirwan JP, Staten MA, Bourey RE, King DS, Holloszy JO. Insulin resistance in aging is related to abdominal obesity. Diabetes. 1993;42:273-281.
32. Iwao S, Iwao N, Muller DC, Elahi D, Shimokata H, Andres R. Effect of aging on the relationship between multiple risk factors and waist circumference. J Am Geriatr Soc. 2000;48:788-794.
33. Ashwell M, Cole TJ, Dixon AK. Ratio of waist circumference to height is strong predictor of intra-abdominal fat. Br Med J. 1996;313:559-560.
34. Fujioka S, Matsuzawa Y, Tokunaga K, Tarui S. Contribution of intraabdominal fat accumulation to the impairment of glucose and lipid metabolism in human obesity. Metab Clin Exp. 1987;36:54-59.
35. Ross R, Fortier L, Hudson R. Separate associations between visceral and subcutaneous adipose tissue distribution, insulin and glucose levels in obese women. Diabetes Care. 1996;19:1404-1411.