Tetramethylpyrazine stimulates cystic fibrosis transmembrane conductance regulator-mediated anion secretion in distal colon of rodents

World Journal of Gastroenterology

Volumn 11, Issue 27, 2005, Pages 4173-4179

  He, Qiong ^a,b   Zhu, Jin Xia ^a,b   Xing, Ying ^a   Tsang, Lai Ling ^b   Yang, Ning ^a,b   Rowlands, Dewi Kenneth ^b   Chung, Yiu Wa ^b   Chan, Hsiao Chang ^b  

^a ZHENGZHOU UNIVERSITY   (China)

^b CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

cAMP; CF mice; Cl ; Colonic mucosa; HCO3 ; Ligustrazine; Tetramethylpyrazine

Indexed keywords

ADENYLATE CYCLASE ACTIVATOR; AMILORIDE; ANION; BICARBONATE; CALCIUM CHELATING AGENT; CHLORIDE ION; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; DICARBOXYLIC ACID DERIVATIVE; DIHYDRO 4,4' DIISOTHIOCYANO 2,2' STILBENEDISULFONIC ACID; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; FORSKOLIN; GLIBENCLAMIDE; ISOBUTYLMETHYLXANTHINE; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; SODIUM CHANNEL BLOCKING AGENT; SODIUM ION; TETRAMETHYLPYRAZINE; TRANSMEMBRANE CONDUCTANCE REGULATOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL TRANSPORT; COLON MUCOSA; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYSTIC FIBROSIS; DESCENDING COLON; DISEASE MODEL; DRUG EFFICACY; DRUG MECHANISM; ELECTROLYTE TRANSPORT; ENZYME INHIBITION; ENZYME SYNTHESIS; HOMOZYGOSITY; MALE; MOUSE; MUTATION; NONHUMAN; PROTEIN FUNCTION; PROTEIN SECRETION; RADIOIMMUNOASSAY; RAT; RODENT; SHORT CIRCUIT CURRENT; SIGNAL TRANSDUCTION;

EID: 23144463365     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.v11.i27.4173     Document Type: Article

References (38)

1. Pan G, Lu S, Ke M, Han S, Guo H, Fang X. Epidemiologic study of the irritable bowel syndrome in Beijing: stratified randomized study by cluster sampling. Chin Med J 2000; 113: 35-39
2. Bommelaer G, Dorval E, Denis P, Czernichow P, Frexinos J, Pelc A, Slama A, El Hasnaoui A. Prevalence of irritable bowel syndrome in the French population according to the Rome I criteria. Gastroenterol Clin Biol 2002; 26: 1118-1123
3. Belai A, Wheeler H, Burnstock G. Innervation of the rat gastrointestinal sphincters: Changes during development and aging. Int J Dev Neurosci 1995; 13: 81-95
4. Burleigh DE. Evidence for a functional cholinergic deficit in human colonic tissue resected for constipation. J Pharm Pharmacol 1988; 40: 55-57
5. Dawson DC. Ion channels and colonic salt transport. Annu Rev Physiol 1991; 53: 321-339
6. Sood R, Bear C, Auerbach W, Reyes E, Jensen T, Kartner N, Riordan JR, Buchwald M. Regulation of CFTR expression and function during differentiation of intestinal epithelial cells. EMBO J 1992; 11: 2487-2494
7. Strong TV, Boehm K, Collins FS. Localization of cystic fibrosis transmembrane conductance regulator mRNA in the human gastrointestinal tract by in situ hybridization. J Clin Invest 1994; 93: 347-354
8. O'Grady SM, Jiang X, Maniak PJ, Birmachu W, Scribner LR, Bulbulian B, Gullikson GW. Cyclic AMP-dependent Cl secretion is regulated by multiple phosphodiesterase subtypes in human colonic epithelial cells. J Membr Biol 2002; 185: 137-144
9. Kunzelmann K, Mall M. Electrolyte transport in the mammalian colon: mechanisms and implications for disease. Physiol Rev 2002; 82: 245-289
10. - secretion across murine duodenum. Am J Physiol 1998; 274(4 Pt 1): G718-726
11. - secretion. J Physiol 1997; 505: 411-423
12. Lencer WI, Delp C, Neutra MR, Madara JL. Mechanism of cholera toxin action on a polarized human intestinal epithelial cell line: role of vesicular traffic. J Cell Biol 1992; 117: 1197-1209
13. Ewe K. Intestinal transport in constipation and diarrhoea. Pharmacology 1988; 36: 73-84
14. Campillos Paez MT, Valles Ugarte ML, San Laureano Palomero T, Perez Hernansaiz M. Constipation and laxative consumption in the elderly. Aten Primaria 2000; 26: 430-432
15. Zhu JX, Chan YM, Tsang LL, Chan LN, Zhou Q, Zhou CX, Chan HC. Cellular signaling mechanisms underlying pharmacological action of Bak Foong Pills on gastrointestinal secretion. Jpn J Physiol 2002; 52: 129-134
16. Xu J, Li YK, Liang ZJ. Effects of tetramethylpyrazine and ferulic acid alone or combined on vascular smooth muscle, blood viscosity and toxicity. Zhongguo Zhongyao Zazhi 1992; 17: 680-682
17. Liu SY, Sylvester DM. Antiplatelet activity of tetramethylpyrazine. Thromb Res 1994; 75: 51-62
18. Lin LN, Wang WT, Xu ZJ. Clinical study on ligustrazine in treating myocardial ischemia and reperfusion injury. Zhongguo Zhongxiyijiehe Zazhi 1997; 17: 261-263
19. Lin CI, Wu SL, Tao PL, Chen HM, Wei J. The role of cyclic AMP and phosphodiesterase activity in the mechanism of action of tetramethylpyrazine on human and dog cardiac and dog coronary arterial tissues. J Pharm Pharmacol 1993; 45: 963-966
20. Kenyon JL, Gibbons WR. Effects of low-chloride solutions on action potentials of sheep cardiac Purkinje fibers. J Gen Physiol 1977; 70: 635-660
21. Snouwaert JN, Brigman KK, Latour AM, Malouf NN, Boucher RC, Smithies O, Koller BH. An animal model for cystic fibrosis made by gene targeting. Science 1992; 257: 1083-1088
22. Ussing HH, Zerahn K. Active transport of sodium as the source of electric current in the short-circuited isolated frog skin. Acta Physiol Scand 1951; 23: 110-127
23. Strabel D, Diener M. Evidence against direct activation of chloride secretion by carbachol in the rat distal colon. Eur J Pharmacol 1995; 274: 181-191
24. Andres H, Rock R, Bridges RJ, Rummel W, Schreiner J. Submucosal plexus and electrolyte transport across rat colonic mucosa. J Physiol 1985; 364: 301-312
25. Schultz BD, DeRoos AD, Venglarik CJ, Singh AK, Frizzell RA, Frizzell RA, Bridges RJ. Glibenclamide blockade of CFTR chloride channels. Am J Physiol 1996; 271(2 Pt 1): L192-200
26. Mall M, Bleich M, Schürlein M, Kuhr J, Seydewitz HH, Brandis M, Greger R, Kunzelmann K. Cholinergic ion secretion in human colon requires coactivation by cAMP. Am J Physiol Gastrointest Liver Physiol 1998; 275(6 Pt 1): G1274-1281
27. Foster ES, Zimmerman TW, Hayslett JP, Binder HJ. Corticosteroid alteration of active electrolyte transport in rat distal colon. Am J Physiol 1983; 245(5 Pt 1): G668-675
28. - cotransporter subtype pNBC1. Am J Physiol Gastrointest Liver Physiol 2003; 284: 37-45
29. - cotransporter of secretory epithelia. Annu Rev Physiol 2000; 62: 515-534
30. +-pump activity in Calu-3 human airway cells. Biochem Biophys Res Commun i2000; 274: 230-235
31. Greger R. Role of CFTR in the colon. Annu Rev Physiol 2000; 62: 467-491
32. - secretion. Gastroebterology 2000; 118: 101-107
33. - with cystic fibrosis transmembrane conductance regulator. JOP 2001; 2: 207-211
34. Dalemans W, Barbry P, Champigny G, Jallat S, Dott K, Dreyer D, Crystal RG, Pavirani A, Lecocq JP, Lazdunski M. Altered chloride ion channel kinetics associated with the F508 cystic fibrosis mutation. Nature 1991; 354: 526-528
35. Barrett KE, Keely SJ. Chloride secretion by the intestinal epithelium: molecular basis and regulatory aspects. Annu Rev Physiol 2000; 62: 535-572
36. Kopito RR. Biosynthesis and degradation of CFTR. Physiol Rev 1999; 79(1 Suppl): S167-173
37. Craven PA, DeRubertis FR. Stimulation of rat colonic mucosal prostaglandin synthesis by calcium and carbamylcholine: relationship to alterations in cyclic nucleotide metabolism. Prostaglandins 1981; 21: 65-81
38. Genz AK, v Engelhardt W, Busche R. Maintenance and regulation of the pH microclimate at the luminal surface of the distal colon of guinea-pig. J Physiol 1999; 517: 507-519