Testing potential Alzheimer vaccines

Scientist

Volumn 16, Issue 2, 2002, Pages 23-24

  Steinberg, Douglas ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

EID: 23044530444     PISSN: 08903670     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (12)

1. D. Schenk et al., "Immunization with amyloid-β attenuates Alzheimer-disease-like pathology in the PDAPP mouse," Nature, 400:173-7, 1999.
2. H.L. Weiner et al., "Nasal administration of amyloid-β peptide decreases cerebral amyloid burden in a mouse model of Alzheimer's disease," Annals of Neurology, 48:567-79, 2000.
3. E.M. Sigurdsson et al., "Immunization with a nontoxic/nonfibrillar amyloid-β homologous peptide reduces Alzheimer's disease-associated pathology in transgenic mice," American Journal of Pathology, 159[2]:439-47, August 2001.
4. C. Cao et al., "Development of plasmid DNA vaccines against beta amyloid protein for prophylactic and/or therapeutic use against transgenic mouse model of amyloid deposition," poster #649.6, 2001 SFN meeting. Abstracts from the SFN meeting are available at www.sfn.org.
5. F. Bard et al., "Peripherally administered antibodies against amyloid b-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease," Nature Medicine, 6:916-9, 2000.
6. B.J. Bacskai et al., "Multiple mechanisms are involved in clearance of amyloid-β by immunotherapy," slide presentation #687.7, 2001 SFN meeting.
7. R.B. DeMattos et al., "Peripheral anti-Abantibody alters CNS and plasma A clearance and decreases brain Ab burden in a mouse model of Alzheimer's disease," Proceedings of the National Academy of Sciences, 98[15]:8850-5, July 17, 2001.
8. C. Janus et al., Aβ peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease," Nature, 408:979-82, 2000.
9. D. Morgan et al., "Aβ peptide vaccination prevents memory loss in an animal model of Alzheimer's disease," Nature, 408:982-5, 2000.
10. J.-C. Dodart et al., "Passive immunization reverses memory deficits but not Alzheimer-like pathology in very old APPV717F transgenic mice," slide presentation #687.12, 2001 SFN meeting.
11. L.A. Kotilinek et al., "Dementia associated with Aβ accumulation reversed with Ab antibodies," poster #546.10, 2001 SFN meeting.
12. D. Morgan et al., "Short-term Aβ vaccinations do not improve cognitive performance in aged, cognitively-impaired APP+PS1 transgenic mice," slide presentation #687.11, 2001 SFN meeting.