Mild and efficient removal of hydroxyethyl unit from 2-hydroxyethyl ether derivatives leading to alcohols

Organic Letters

Volumn 7, Issue 15, 2005, Pages 3303-3306

  Fujioka, Hiromichi ^a   Ohba, Yusuke ^a   Hirose, Hideki ^a   Murai, Kenichi ^a   Kita, Yasuyuki ^a  

^a OSAKA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 23044512119     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol051135i     Document Type: Article

References (21)

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18. 1H NMR.
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20. For deprotection of acetals by CAN, see: (a) Ates, A.; Gautier, A.; Leroy, B.; Plancher, J.-M.; Quesnel, Y.; Vanherck, J.-C.; Markó, I. E. Tetrahedron 2003, 59, 8989.
21. (b) Markó, I. E.; Ates, A.; Gautier, A.; Leroy, B.; Plancher, J.-M; Quesnel, Y.; Vanherck, J.-C. Angew. Chem., Int. Ed. 1999, 38, 3207. For hydrolysis of acetal units in compounds 7 and 10, the reactions were carried out at 60°C and excess amounts of CAN were used.