Epithelial cell deformation during surfactant-mediated airway reopening: A theoretical model

Journal of Applied Physiology

Volumn 99, Issue 2, 2005, Pages 458-471

  Naire, Shailesh ^a   Jensen, Oliver E ^b  

^a HERIOT WATT UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

Atelectrauma; Fluid structure interaction; Recruitment; Surface tension; Volutrauma

Indexed keywords

CALFACTANT; LUNG SURFACTANT;

ADSORPTION; ARTICLE; ATELECTASIS; CELL SHAPE; HUMAN; LUNG ALVEOLUS EPITHELIUM; LUNG ALVEOLUS SURFACE TENSION; LUNG COLLAPSE; LUNG COMPLIANCE; PHYSICAL CHEMISTRY; PHYSICAL STRESS; PRIORITY JOURNAL; SHEAR STRESS; THEORETICAL MODEL;

ANIMALS; CELL SIZE; COMPUTER SIMULATION; ELASTICITY; EPITHELIAL CELLS; FRICTION; HUMANS; LUNG; MODELS, BIOLOGICAL; PRESSURE; PULMONARY SURFACTANTS; RESPIRATORY MECHANICS; RESPIRATORY MUCOSA; SURFACE TENSION;

EID: 23044457753     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/japplphysiol.00796.2004     Document Type: Article

References (62)

1. Alcaraz J, Buscemi L, Grabulosa M, Trepat X, Fabry B, Farre R, and Navajas D. Microrheology of human lung epithelial cells measured by atomic force microscopy. Biophys J 84: 2071-2079, 2003.
2. Alencar AM, Arold SP, Buldyrev SV, Majumdar A, Stamenovic D, Stanley HE, and Suki B. Physiology-dynamic instabilities in the inflating lung. Nature 417: 809-811, 2002.
3. Berrios JC, Schroeder MA, and Hubmayr RD. Mechanical properties of alveolar epithelial cells in culture. J Appl Physiol 91: 65-73, 2001.
4. Bilek AM, Dee KC, and Gaver DP. Mechanisms of surface-tension-induced epithelial cell damage in a model of pulmonary airway reopening. J Appl Physiol 94: 770-783, 2003.
5. Bretherton FP. The motion of long bubbles in tubes. J Fluid Mech 10: 166-188, 1961.
6. Cavanaugh KJ and Margulies SS. Measurement of stretch-induced loss of alveolar epithelial barrier integrity with a novel in vitro method. Am J Physiol Cell Physiol 283: C1801-C1808, 2002.
7. Chadwick RS. Axisymmetric indentation of a thin incompressible elastic layer. SIAM J Appl Math 62: 1520-1530, 2002.
8. Charras GT and Horton MA. Determination of cellular strains by combined atomic force microscopy and finite element modeling. Biophys J 83: 858-879. 2002.
9. Dreyfuss D and Saumon G. Ventilator-induced lung injury-lessons from experimental studies. Am J Respir Crit Care Med 157: 294-323, 1998.
10. Elad D, Kamm RD, and Shapiro AH. Tube law for the intrapulmonary airway. J Appl Physiol 65: 7-13, 1988.
11. Gajic O, Lee J, Doerr CH, Berrios JC, Myers JL, and Hubmayr RD. Ventilator-induced cell wounding and repair in the intact lung. Am J Respir Crit Care Med 167: 1057-1063, 2003.
12. Gattinoni L, Caironi P, Pelosi P, and Goodman LR. What has computed tomography taught us about the acute respiratory distress syndrome? Am J Respir Crit Care Med 164: 1701-1711, 2001.
13. Gattinoni L, Carlesso E, Cadringher P, Valenza F, Vagginelli F, and Chiumello D. Physical and biological triggers of ventilator-induced lung injury and its prevention. Eur Respir J 22: 15-25, 2003.
14. Gaver DP, Halpern D, and Jensen OE. Surfactant and airway liquid flows. In: Molecular Mechanisms in Lung Surfactant (Dys)function, edited by Nag K. New York: Dekker, 2005.
15. Gaver DP, Halpern D, Jensen OE, and Grotberg JB. The steady motion of a semi-infinite bubble through a flexible-walled channel. J Fluid Mech 319: 25-65, 1996.
16. Gaver DP, Samsel RW, and Solway J. Effects of surface-tension and viscosity on airway reopening. J Appl Physiol 69: 74-85, 1990.
17. Ghadiali SN. Experimental and Computational Investigations of Surfactant Physicochemical Behavior During Conditions Emulating the Opening of Pulmonary Airways (PhD thesis). New Orleans, LA: Tulane Universty, 2000.
18. Ghadiali SN and Gaver DP. The influence of nonequilibrium surfactant dynamics on the flow of a semi-infinite bubble in a rigid cylindrical capillary tube. J Fluid Mech 478: 165-196, 2003.
19. Ghadiali SN and Gaver DP. An investigation of pulmonary surfactant physicochemical behavior under airway reopening conditions. J Appl Physiol 88: 493-506, 2000.
20. Goldsmith LS, Greenspan JS, Rubenstein SD, Wolfson MR, and Shaffer TH. Immediate improvement in lung-volume after exogenous surfactant-alveolar recruitment versus increased distension. J Pediatr 119: 424-428, 1991.
21. Haider MA and Holmes MH. Indentation of a thin compressible elastic layer-approximate analytic and numerical-solutions for rigid flat indenters. J Mech Phys Solids 43: 1199-1219, 1995.
22. Halpern D and Grotberg JB. Surfactant effects on fluid-elastic instabilities of liquid-lined flexible tubes-a model of airway-closure. J Biomech Eng 115: 271-277, 1993.
23. Halpern D, Naire S, Jensen OE, and Gaver DP. Unsteady bubble propagation in a flexible-walled channel: predictions of a viscous stick-slip instability. J Fluid Mech 528: 53-86, 2005.
24. Halter JM, Steinberg JM, Schiller HJ, DaSilva M, Gatto LA, Lanclas S, and Nieman GF. Positive end-expiratory pressure after a recruitment maneuver prevents both alveolar collapse and recruitment/derecruitment. Am J Respir Crit Care Med 167: 1620-1626, 2003.
25. Hammerschmidt S, Kuhn H, Grasenack T, Gessner C, and Wirtz H. Apoptosis and necrosis induced by cyclic mechanical stretching in alveolar type II cells. Am J Respir Cell Mol Biol 30: 396-402, 2004.
26. Hazel AL and Heil M. Three-dimensional airway reopening: the steady propagation of a semi-infinite bubble into a buckled elastic tube. J Fluid Mech 478: 47-70, 2003.
27. Heil M. Finite Reynolds number effects in the propagation of an air finger into a liquid-filled flexible-walled channel. J Fluid Mech 424: 21-44, 2000.
28. Howell PD, Waters SL, and Grotberg JB. The propagation of a liquid bolus along a liquid-lined flexible tube. J Fluid Mech 406: 309-335, 2000.
29. Hsu S, Strohl K, and Jamieson A. Role of viscoelasticity in a tube model of airway reopening. I. Non-Newtonian sols. J Appl Physiol 76: 2481-2489, 1994.
30. Hubmayr RD. Perspective on lung injury and recruitment-a skeptical look at the opening and collapse story. Am J Respir Crit Care Med 165: 1647-1653, 2002.
31. Jacob AM and Gaver DP. An investigation of the influence of cell topography on epithelial mechanical stresses during pulmonary airway reopening. Phys Fluids 17: 031502, 2005.
32. Jensen OE and Horsburgh MK. Modelling the reopening of liquid-lined lung airways. In: Wall-Fluid Interactions in Physiological Flows, edited by Collins MW, Pontrelli G, and Atherton MA. Southampton, UK: WIT Press. 2004.
33. Jensen OE, Horsburgh MK, Halpern D, and Gaver DP. The steady propagation of a bubble in a flexible-walled channel: asymptotic and computational models. Phys Fluids 14: 443-457, 2002.
34. Kamm RD. Airway wall mechanics. Annu Rev Biomed Eng 1: 47-72, 1999.
35. Kay SS, Bilek AM, Kay CD, and Gaver DP. Pressure gradient, not exposure duration, determines the extent of epithelial cell damage in a model of pulmonary airway reopening. J Appl Physiol 97: 269-276, 2004.
36. Lambert RK, Codd SL, Alley MR, and Pack RJ. Physical determinants of bronchial mucosal folding. J Appl Physiol 77: 1206-1216, 1994.
37. Laurent VM, Henon S, Planus E, Fodil R, Balland M, Isabey D, and Gallet F. Assessment of mechanical properties of adherent living cells by bead micromanipulation: comparison of magnetic twisting cytometry vs optical tweezers. J Biomech Eng 124: 408-421, 2002.
38. Macklem PT, Proctor DF, and Hogg JC. Stability of peripheral airways. Respir Physiol 8: 191-203, 1970.
39. Maniotis AJ, Chen CS, and Ingber DE. Demonstration of mechanical connections between integrins cytoskeletal filaments, and nucleoplasm that stabilize nuclear structure. Proc Natl Acad Sci USA 94: 849-854, 1997.
40. Martynowicz MA, Minor TA, Walters BJ, and Hubmayr RD. Regional expansion of oleic acid-injured lungs. Am J Respir Crit Care Med 160: 250-258, 1999.
41. Martynowicz MA, Walters BJ, and Hubmayr RD. Mechanisms of recruitment in oleic acid-injured lungs. J Appl Physiol 90: 1744-1753, 2001.
42. McNeil PL and Steinhardt RA. Plasma membrane disruption: repair, prevention, adaptation. Annu Rev Cell Dev Biol 19: 697-731, 2003.
43. Muscedere JG, Mullen JBM, Gan K, and Slutsky AS. Tidal ventilation at low airway pressures can augment lung injury. Am J Respir Crit Care Med 149: 1327-1334, 1994.
44. Naire S and Jensen OE. An asymptotic model of unsteady airway reopening. J Biomech Eng 125: 823-831, 2003.
45. Naureckas ET, Dawson CA, Gerber BS, Gaver DP, Gerber HL, Linehan JH, Solway J, and Samsel RW. Airway reopening pressure in isolated rat lungs. J Appl Physiol 76: 1372-1377, 1994.
46. Otis DR, Johnson M, Pedley TJ, and Kamm RD. Role of pulmonary surfactant in airway-closure - A computational study. J Appl Physiol 75: 1323-1333, 1993.
47. Perun ML and Gaver DP. An experimental-model investigation of the opening of a collapsed untethered pulmonary airway. J Biomech Eng 117: 245-253, 1995.
48. Perun ML and Gaver DP. Interaction between airway lining fluid forces and parenchymal tethering during pulmonary airway reopening. J Appl Physiol 79: 1717-1728, 1995.
49. Ricard JD, Dreyfuss D, and Saumon G. Ventilator-induced lung injury. Eur Respir J 22: 2-9, 2003.
50. Scarpelli EM. Physiology of the alveolar surface network. Comp Biochem Physiol A Mol Integr Physiol 135: 39-104, 2003.
51. Sera T, Fujioka H, Yokota H, Makinouchi A, Himeno R, Schroter RC, and Tanishita K. Localized compliance of small airways in excised rat lungs using microfocal X-ray computed tomography. J Appl Physiol 96: 1665-1673, 2004.
52. Sera T, Fujioka H, Yokota H, Makinouchi A, Himeno R, Schroter RC, and Tanishita K. Three-dimensional visualization and morphometry of small airways from microfocal X-ray computed tomography. J Biomech 36: 1587-1594, 2003.
53. Slutsky AS. Lung injury caused by mechanical ventilation. Chest 116: 9-15, 1999.
54. Taskar V, John J, Evander E, Robertson B, and Jonson B. Surfactant dysfunction makes lungs vulnerable to repetitive collapse and reexpansion. Am J Respir Crit Care Med 155: 313-320, 1997.
55. Taskar V, John J, Evander E, Wollmer P, Robertson B, and Jonson B. Healthy lungs tolerate repetitive collapse and reopening during short periods of mechanical ventilation. Acta Anaesthesiol Scand 39: 370-376, 1995.
56. Tschumperlin DJ, Oswari J, and Margulies SS. Deformation-induced injury of alveolar epithelial cells-effect of frequency, duration, and amplitude. Am J Respir Crit Care Med 162: 357-362, 2000.
57. Uhlig S. Mechanotransduction in the lung-ventilation-induced lung injury and mechanotransduction: stretching it too far? Am J Physiol Lung Cell Mol Physiol 282: L892-L896, 2002.
58. Vlahakis ME and Hubmayr RD. Invited review: Plasma membrane stress failure in alveolar epithelial cells. J Appl Physiol 89: 2490-2496, 2000.
59. Vlahakis NE, Schroeder MA, Limper AH, and Hubmayr RD. Stretch induces cytokine release by alveolar epithelial cells in vitro. Am J Physiol Lung Cell Mol Physiol 277: L167-L173, 1999.
60. Waters SL and Grotberg JB. The propagation of a surfactant laden liquid plug in a capillary tube. Phys Fluids 14: 471-480, 2002.
61. Yap DYK and Gaver DP. The influence of surfactant on two-phase flow in a flexible-walled channel under bulk equilibrium conditions. Phys Fluids 10: 1846-1863, 1998.
62. Yap DYK, Liebkemann WD, Solway J, and Gaver DP. Influences of parenchymal tethering on the reopening of closed pulmonary airways. J Appl Physiol 76: 2095-2105, 1994.