Editorial - Tutorial on microarray gene expression experiments: An introduction

Methods of Information in Medicine

Volumn 44, Issue 3, 2005, Pages 392-399

  Repsilber, Dirk ^a,d   Mansmann, U ^b   Brunner, E ^c   Ziegler, A ^a  

^a UNIVERSITY OF LÜBECK   (Germany)

^b UNIVERSITY OF HEIDELBERG   (Germany)

^c UNIVERSITY OF GÖTTINGEN   (Germany)

^d UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; MESSENGER RNA;

BIOINFORMATICS; DATA ANALYSIS; DNA MICROARRAY; GENE CONTROL; GENE EXPRESSION; GENE EXPRESSION PROFILING; HEALTH CARE PLANNING; INTERDISCIPLINARY COMMUNICATION; PRIORITY JOURNAL; REVIEW; BOOK; EDITORIAL; EDUCATION; GENETICS; HUMAN; MATHEMATICAL COMPUTING; MEDICAL INFORMATICS; METHODOLOGY;

DICTIONARIES; EDUCATION; GENE EXPRESSION PROFILING; GENETIC RESEARCH; HUMANS; MATHEMATICAL COMPUTING; MEDICAL INFORMATICS COMPUTING; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS;

EID: 22944485296     PISSN: 00261270     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0038-1633982     Document Type: Review

References (31)

1. Slonim DK. Transcriptional profiling in cancer: the path to clinical pharmacogenomics. Pharmacogenomics 2001; 2 (2): 123-36.
2. Nevins JR, Huang ES, Dressman H, Pittman J, Huang AT, West M. Towards integrated clinicogenomic models for personalized medicine: combining gene expression signatures and clinical factors in breast cancer outcomes prediction. Hum Mol Genet 2003; 12 Spec No 2: R153-7.
3. Jain KK. Applications of biochips: from diagnostics to personalized medicine. Curr Opin Drug Discov Devel 2004; 7 (3): 285-9.
4. Raetz EA, Moos PJ. Impact of microarray technology in clinical oncology. Cancer Invest 2004; 22 (2): 312-20.
5. Lander ES. Array of hope. Nat Genet 1999; 21 (1 Suppl): 3-4.
6. Hicks J. Genome, proteome, and metabolome: where are we going? Ultrastruct Pathol 2003; 27 (5): 289-94.
7. Joos L, Eryuksel E, Bratsche MH. Functional genomics and gene microarrays - the use in research and clinical medicine. Swiss Med Wkly 2003; 133 (3-4): 31-8.
8. Dobrin SE, Stephan DA. Integrating microarrays into disease-gene identification strategies. Expert Rev Mol Diagn 2003; 3 (3): 375-85.
9. Lackie JM, Dow JAT. The dictionary of cell & molecular biology. London: Academic Press; 1999.
10. Celis JE, Kruhøffer M, Gromova I, Frederiksen C, Østergaard M, Thykjaer T, et al. Gene expression profiling: monitoring transcription and translation products using DNA microarrays and proteomics. FEBS Lett 2000; 480 (1): 2-16.
11. Brazma A, Vilo J. Gene expression data analysis. FEBS Lett 2000; 480(1): 17-24.
12. Somogyi R, Sniegoski CA. Modeling the complexity of genetic networks: Understanding multigenic and pleiotropic regulation. Complexity 1996; 1 (6): 45-63.
13. Southern EM. Detection of specific sequences among DNA fragments separated by gel electrophoresis. J Mol Biol 1975; 98 (3): 503-17.
14. Shalon D, Smith SJ, Brown PO. A DNA microarray system for analyzing complex DNA samples using two-color fluorescent probe hybridization. Genome Res 1996; 6 (7): 639-45.
15. Stears RL, Martinsky T, Schena M. Trends in microarray analysis. Nat Med 2003; 9 (1): 140-5.
16. McGall GH, Christians FC. High-density genechip oligonucleotide probe arrays. Adv Biochem Eng Biotechnol 2002; 77: 21-42.
17. Sebastiani P, Gussoni E, Kohane IS, Ramoni MF. Statistical challenges in functional genomics. Statistical Science 2003; 18(1): 33-70.
18. Repsilber D, Ziegler A. Two-color microarray experiments: Technology and sources of variance. Methods Inf Med 2005; 44: 400-4 (this issue).
19. Rahnenführer J. Image analysis for cDNA microarrays. Methods Inf Med 2005; 44: 405-7 (this issue).
20. Hartmann O. Quality control for microarray experiments. Methods Inf Med 2005; 44: 408-13 (this issue).
21. Boes T., Neuhäuser M. Normalization for Affymetrix GeneChips. Methods Inf Med 2005; 44: 414-7 (this issue).
22. Ittrich C. Normalization for two channel microarray data. Methods Inf Med 2005; 44: 418-22 (this issue).
23. Bretz F, Landgrebe J, Brunner E. Design and analysis of two-color microarray experiments using linear models. Methods Inf Med 2005; 44: 423-30 (this issue).
24. Bretz F, Landgrebe J, Brunner E. Multiplicity Issues in Microarray Experiments. Methods Inf Med 2005; 44: 431-7 (this issue).
25. Markowetz F, Spang R. Molecular diagnosis: classification, model selection and performance evaluation. Methods Inf Med 2005; 44: 438-43 (this issue).
26. Rahnenfuhrer J. Clustering algorithms and other exploratory methods for microarray data analysis. Methods Inf Med 2005; 44: 444-8 (this issue).
27. Mansmann U, Meister R. Testing differential gene expression in functional groups: Goeman's global test versus an ANCOVA-approach. Methods Inf Med 2005; 44: 449-53 (this issue).
28. Mansmann U. Genomic profiling: interplay between clinical epidemiology, bioinformatics and biostatistics. Meth Inf Med 2005; 44: 454-60 (this issue).
29. Repsilber D. L. Fink, M. Jacobsen, O. Bläsing, Ziegler A. Sample selection for microarray gene expression studies. Methods Inf Med 2005; 44: 461-7 (this issue).
30. Brors B. Microarray annotation and biological information on function. Methods Inf Med 2005; 44: 468-72 (this issue).
31. Post-genomic cultures. Nature 2001; 409 (6820): 545.