Oral delivery of G protein-coupled receptor modulators: An explanation for the observed class difference

Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 16, 2005, Pages 3658-3664

  Beaumont, Kevin ^a   Schmid, Esther ^a   Smith, Dennis A ^a  

^a PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

APOMORPHINE; ATROPINE; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; CEVIMELINE; CIMETIDINE; CLONIDINE; CLOZAPINE; DARIFENACIN; DIPHENHYDRAMINE; DOPEXAMINE; ELETRIPTAN; EPHEDRINE; G PROTEIN COUPLED RECEPTOR; LORATADINE; MARAVIROC; METHYSERGIDE; MONTELUKAST; OLANZAPINE; PIMOZIDE; PIRENZEPINE; PRAZOSIN; RANITIDINE; RIMONABANT; SCOPOLAMINE; SULPIRIDE; SUMANIROLE; SUMATRIPTAN; TOLTERODINE; UNINDEXED DRUG;

ARTICLE; CLINICAL TRIAL; DRUG ABSORPTION; DRUG DELIVERY SYSTEM; DRUG METABOLISM; DRUG POTENCY; DRUG STRUCTURE; DRUG TARGETING; HUMAN; HYDROGEN BOND; LIPOPHILICITY; MOLECULAR WEIGHT; PHYSICAL CHEMISTRY; PROTEIN ANALYSIS;

ADMINISTRATION, ORAL; CRYSTALLIZATION; DRUG DESIGN; DRUG STABILITY; HUMANS; HYDROGEN BONDING; LIGANDS; MOLECULAR STRUCTURE; MOLECULAR WEIGHT; PHARMACEUTICAL PREPARATIONS; RECEPTORS, G-PROTEIN-COUPLED; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 22844448564     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.05.042     Document Type: Article

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