Prostaglandin E2 receptor EP4 agonist induces Bcl-xL and independently activates proliferation signals in mouse primary hepatocytes

Journal of Gastroenterology

Volumn 40, Issue 6, 2005, Pages 610-616

  Kataoka, Kojiro ^a   Takikawa, Yasuhiro ^a   Lin, Shi De ^a   Suzuki, Kazuyuki ^a  

^a IWATE MEDICAL UNIVERSITY   (Japan)

Author keywords

Bcl xL; ERK; Hepatocyte apoptosis; Proliferation; Prostaglandin E2 receptor agonist

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; CYCLIN D1; EPIDERMAL GROWTH FACTOR RECEPTOR; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; ONOAE 1437; PROSTAGLANDIN E RECEPTOR; PROSTAGLANDIN E2 DERIVATIVE; PROTEIN BCL XL; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL PROLIFERATION; CELL REGENERATION; CELL STIMULATION; DRUG TARGETING; LIVER CELL; LIVER FAILURE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; BCL-X PROTEIN; BLOTTING, WESTERN; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CELL PROLIFERATION; CELLS, CULTURED; CYCLINS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FLAVONOIDS; HEPATOCYTES; MALE; MICE; MICE, INBRED C57BL; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-BCL-2; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTORS, PROSTAGLANDIN E; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION;

EID: 22844448233     PISSN: 09441174     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00535-005-1595-y     Document Type: Article

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