In vitro binding of leukotriene B4 (LTB4) to human serum albumin: Evidence from spectroscopic, molecular modeling, and competitive displacement studies

Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 16, 2005, Pages 3725-3731

  Zsila, Ferenc ^a   Bikádi, Zsolt ^a   Lockwood, Samuel F ^b  

^a CHEMICAL RESEARCH CENTER   (Hungary)

^b HAWAII BIOTECH INC   (United States)

Author keywords

Circular dichroism spectroscopy; Human serum albumin; Ibuprofen; Induced chirality; Leukotriene B4; Palmitic acid

Indexed keywords

HUMAN SERUM ALBUMIN; IBUPROFEN; LEUKOTRIENE B4; LONG CHAIN FATTY ACID; PALMITIC ACID;

ABSORPTION SPECTROSCOPY; ARTICLE; BINDING AFFINITY; BINDING SITE; CIRCULAR DICHROISM; COMPLEX FORMATION; CRYSTAL STRUCTURE; DRUG BINDING; IN VITRO STUDY; MOLECULAR MODEL; NONLINEAR REGRESSION ANALYSIS; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; SPECTROSCOPY; TITRIMETRY; VIBRATION;

BINDING SITES; BINDING, COMPETITIVE; CIRCULAR DICHROISM; HUMANS; IBUPROFEN; LEUKOTRIENE B4; LIGANDS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; SERUM ALBUMIN; SPECTROPHOTOMETRY, ULTRAVIOLET; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 22844445364     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.05.125     Document Type: Article

References (14)

1. B. Samuelsson, S.E. Dahlen, J.A. Lindgren, C.A. Rouzer, and C.N. Serhan Science 237 1987 1171
2. P. Hedqvist, J. Raud, U. Palmertz, M. Kumlin, and S.E. Dahlen Adv. Prostaglandin Thromboxane Leukot. Res. 21B 1991 537
3. S.W. Crooks, and R.A. Stockley Int. J. Biochem. Cell Biol. 30 1998 173
4. E.S. Silverman, and J.M. Drazen Proc. Assoc. Am. Physicians 111 1999 525
5. R. Spanbroek, R. Grabner, K. Lotzer, M. Hildner, A. Urbach, K. Ruhling, M.P. Moos, B. Kaiser, T.U. Cohnert, T. Wahlers, A. Zieske, G. Plenz, H. Robenek, P. Salbach, H. Kuhn, O. Radmark, B. Samuelsson, and A.J. Habenicht Proc. Natl. Acad. Sci. U.S.A. 100 2003 1238
6. T. Peters All about albumin 1996 Academic Press San Diego
7. D.C. Carter, and J.X. Ho Adv. Protein Chem. 45 1994 153
8. M. Benz, O. Werz, R. Jacob, and D. Steinhilber Inflamm. Res. 46 1997 366
9. J. Haeggstrom, F. Fitzpatrick, O. Radmark, and B. Samuelsson FEBS Lett. 164 1983 181
10. G. Folco, E. Granstrom, and H. Kindahl FEBS Lett. 82 1977 321
11. F.A. Fitzpatrick, D.R. Morton, and M.A. Wynalda J. Biol. Chem. 257 1982 4680
12. M. Sugiura, H. Beierbeck, P.C. Belanger, and G. Kotovych J. Am. Chem. Soc. 106 1984 4021
13. A.A. Bhattacharya, T. Grune, and S. Curry J. Mol. Biol. 303 2000 721
14. K. Yamasaki, M.H. Rahman, Y. Tsutsumi, T. Maruyama, S. Ahmed, U. Kragh-Hansen, and M. Otagiri AAPS PharmSciTech. 1 2000 E12