Mechanisms contributing to the exacerbated epileptiform activity in hippocampal slices expressing a C-terminal truncated GABAB2 receptor subunit

Epilepsy Research

Volumn 65, Issue 1-2, 2005, Pages 41-51

  Thuault, Sébastien J ^a,b,c   Brown, Jon T ^a,b   Calver, Andrew R ^a   Collingridge, Graham L ^b   Randall, Andrew ^a   Davies, Ceri H ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

^b UNIVERSITY OF BRISTOL   (United Kingdom)

^c Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

Epilepsy; Epileptiform activity; GABAB receptor; Hippocampal slice; Synaptic transmission; Transgenic mice

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID A RECEPTOR BLOCKING AGENT; 4 AMINOBUTYRIC ACID B RECEPTOR; 4 AMINOPYRIDINE; 6 NITRO 7 SULFAMOYLBENZO[F]QUINOXALINE 2,3 DIONE; BICUCULLINE; IONOTROPIC RECEPTOR ANTAGONIST; MAGNESIUM; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; POTASSIUM CHANNEL BLOCKING AGENT; PROTEIN SUBUNIT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN SLICE; CARBOXY TERMINAL SEQUENCE; CLINICAL PROTOCOL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISEASE EXACERBATION; EPILEPTIC DISCHARGE; EXTRACELLULAR SPACE; HIPPOCAMPUS; MOLECULAR BIOLOGY; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; TRANSGENIC MOUSE;

4-AMINOPYRIDINE; ANIMALS; BICUCULLINE; DRUG INTERACTIONS; ELECTRIC STIMULATION; EMBRYO; EPILEPSY; EXCITATORY AMINO ACID ANTAGONISTS; EXCITATORY POSTSYNAPTIC POTENTIALS; GABA ANTAGONISTS; GENE DELETION; HIPPOCAMPUS; MAGNESIUM; MEMBRANE POTENTIALS; MICE; MICE, KNOCKOUT; PHOSPHINIC ACIDS; POTASSIUM CHANNEL BLOCKERS; PROPANOLAMINES; PYRAMIDAL CELLS; QUINOLINIUM COMPOUNDS; RECEPTORS, GABA-B; TIME FACTORS; VALINE;

EID: 22844437551     PISSN: 09201211     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.eplepsyres.2005.04.004     Document Type: Article

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