High-throughput purification of single compounds and libraries

Journal of Combinatorial Chemistry

Volumn 7, Issue 4, 2005, Pages 546-553

  Schaffrath, Mathias ^a   Von Roedern, Erich ^a   Hamley, Peter ^a   Stilz, Hans Ulrich ^a  

^a SANOFI AVENTIS DEUTSCHLAND GMBH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; AUTOMATION; COMBINATORIAL CHEMISTRY; FRACTIONATION; INSTRUMENTATION; METHODOLOGY;

AUTOMATION; CHEMICAL FRACTIONATION; COMBINATORIAL CHEMISTRY TECHNIQUES;

EID: 22844437343     PISSN: 15204766     EISSN: None     Source Type: Journal    
DOI: 10.1021/cc0498128     Document Type: Article

References (9)

1. Cork, D.; Hird, N. S. Drug Discovery Today 2002, 7, 56-63.
2. Jones, M. Drug Discovery Today 2001, 6, 219-220.
3. Weber, A.; von Roedern, E.; Stilz, H. U. J. Comb. Chem. 2005, 7, 178-184.
4. Isbell, J.; Xu, R.; Cai, Z.; Kassel, D. B. J. Comb. Chem. 2002, 4, 600-611.
5. An overview of the current situation in high-throughput purification in the field of medicinal chemistry can by foundin the following literature: (a) Ripka, W. C.; Barker, G.; Krakover, J. Drug Discovery Today 2001, 6, 471-477.
6. (b) Everett J.; Gardner, M.; Pullen, F.; Smith, G. F.; Snarey, M.; Terrett, N. Drug Discovery Today 2001, 6, 779-785.
7. (c) Hughes, I.; Huter, D. Curr. Opin. Chem. Biol. 2001, 5, 243-247.
8. (d) Yan, B.; Collins, N.; Wheatley, J.; Irving, M.; Leopold, K.; Chan, C.; Shornikov, A.; Fang, L.; Lee, A.; Stock, M.; Zhao, J. J. Comb. Chem. 2004, 6, 255-261.
9. (e) Ventura, M.; Farrell, W.; Aurigemma, C.; Tivel, K.; Greig, M.; Wheatley, J.; Yanovsky, A.; Milgram, K. E.; Dalesandro, D.; DeGuzman, R.; Tran, P.; Nguyen, L.; Chung, L.; Gron, O.; Koch, C. A. J. Chromatography 2004, 1036, 7-13.