In vitro reactivation potency of some acetylcholinesterase reactivators against sarin- and cyclosarin-induced inhibitions

Journal of Applied Toxicology

Volumn 25, Issue 4, 2005, Pages 296-300

  Kuca, Kamil ^a,b   Cabal, Jiri ^a   Jun, Daniel ^a   Kassa, Jiri ^a   Bartosová, Lucie ^a   Kunesová, Gabriela ^a  

^a UNIVERSITY OF DEFENCE   (Czech Republic)

^b UNIVERSITY OF DEFENCE   (Czech Republic)

Author keywords

Acetylcholinesterase; Cyclosarin; Nerve agents; Oxime; Reactivation; Sarin

Indexed keywords

1 (4 CARBAMOYLPYRIDINIO) 1' (2 HYDROXYIMINOMETHYLPYRIDINIO)DIMETHYL ETHER; 1 (4 CARBAMOYLPYRIDINIO) 4 (2 HYDROXYIMINOMETHYLPYRIDINIO) 2 BUTENE DIBROMIDE; 1 [2,4 BIS(HYDROXYIMINOMETHYL)PYRIDINIO] 1' (4 CARBAMOYLPYRIDINIO)DIMETHYL ETHER DIIODIDE; ACETYLCHOLINESTERASE; CYCLOSARIN; OBIDOXIME; PRALIDOXIME; SARIN; TOXOGONINE; TRIMEDOXIME; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BRAIN HOMOGENATE; CHOLINESTERASE INHIBITION; DISSOCIATION CONSTANT; DRUG EFFICACY; DRUG POTENCY; DRUG STRUCTURE; ENZYME REACTIVATION; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; BRAIN; CHEMICAL WARFARE AGENTS; CHOLINESTERASE INHIBITORS; CHOLINESTERASE REACTIVATORS; KINETICS; ORGANOPHOSPHORUS COMPOUNDS; RATS; RATS, WISTAR; SARIN;

EID: 22844435631     PISSN: 0260437X     EISSN: None     Source Type: Journal    
DOI: 10.1002/jat.1065     Document Type: Article

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