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Volumn 15, Issue 7, 2005, Pages 875-887

Therapeutic potential of CDK5 inhibitors to promote corneal epithelial wound healing

Author keywords

Cornea; Cyclin dependent kinase; Diabetic keratopathy; Epithelium; Infectious keratitis; Neurotorophic keratopathy; Wound healing

Indexed keywords

2 AMINOTHIAZOLE DERIVATIVE; ALOISINE; ANTIGLAUCOMA AGENT; ANTISENSE OLIGONUCLEOTIDE; BENZOPYRAN DERIVATIVE; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CYCLIN DEPENDENT KINASE 5; CYCLIN DEPENDENT KINASE 5 INHIBITOR; CYCLIN DEPENDENT KINASE INHIBITOR; DICLOFENAC; FLAVONE DERIVATIVE; INDAZOLE DERIVATIVE; INDIRUBIN; INDOLE DERIVATIVE; ISOXAZOLE DERIVATIVE; OLOMOUCINE; PAULLONE DERIVATIVE; PHENOL DERIVATIVE; PHTHALAZINE DERIVATIVE; PYRAZINE DERIVATIVE; PYRAZOLE DERIVATIVE; PYRIDINE DERIVATIVE; PYRIDO[2,3 D]PYRIMIDINE DERIVATIVE; PYRIMIDINE DERIVATIVE; PYRIMIDINONE DERIVATIVE; PYRROLE DERIVATIVE; ROSCOVITINE; THIAZOLE DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG; UREA DERIVATIVE;

EID: 22744441684     PISSN: 13543776     EISSN: None     Source Type: Journal    
DOI: 10.1517/13543776.15.7.875     Document Type: Review
Times cited : (5)

References (68)
  • 3
    • 0030802113 scopus 로고    scopus 로고
    • Expression of CDK-5, p35, and CDK5-associated kinase activity in the developing rat lens
    • GAO CY, ZAKERI Z, ZHU Y, HE HY, ZELENKA PS: Expression of CDK-5, p35, and CDK5-associated kinase activity in the developing rat lens. Develop. Genetics (1997) 20:267-275.
    • (1997) Develop. Genetics , vol.20 , pp. 267-275
    • Gao, C.Y.1    Zakeri, Z.2    Zhu, Y.3    He, H.Y.4    Zelenka, P.S.5
  • 4
    • 0035877992 scopus 로고    scopus 로고
    • Expression of the neuronal cyclin-dependent kinase 5 activator p35Nck5a in human monocytic cells is associated with differentiation
    • CHEN F, STUDZINSKI GP: Expression of the neuronal cyclin-dependent kinase 5 activator p35Nck5a in human monocytic cells is associated with differentiation. Blood (2001) 97:3763-3767.
    • (2001) Blood , vol.97 , pp. 3763-3767
    • Chen, F.1    Studzinski, G.P.2
  • 5
    • 0034786018 scopus 로고    scopus 로고
    • Structure and regulation of the CDK5-p25(nck5a) complex
    • TARRICONE C, DHAVAN R, PENG J et al.: Structure and regulation of the CDK5-p25(nck5a) complex. Mol. Cell Neurosci. (2001) 8:657-669.
    • (2001) Mol. Cell Neurosci. , vol.8 , pp. 657-669
    • Tarricone, C.1    Dhavan, R.2    Peng, J.3
  • 6
    • 0033710860 scopus 로고    scopus 로고
    • Cables links CDK5 and c-Abl and facilitates CDK5 tyrosine phosphorylation, kinase upregulation, and neurite outgrowth
    • ZUKERBERG LR, PATRICK GN, NIKOLIC M et al.: Cables links CDK5 and c-Abl and facilitates CDK5 tyrosine phosphorylation, kinase upregulation, and neurite outgrowth. Neuron (2000) 26:633-646.
    • (2000) Neuron , vol.26 , pp. 633-646
    • Zukerberg, L.R.1    Patrick, G.N.2    Nikolic, M.3
  • 7
    • 18644374595 scopus 로고    scopus 로고
    • Fyn and CDK5 mediate semaphorin-3A signaling, which is involved in regulation of dendrite orientation in cerebral cortex
    • SASAKI Y, CHENG C, UCHIDA Y et al.: Fyn and CDK5 mediate semaphorin-3A signaling, which is involved in regulation of dendrite orientation in cerebral cortex. Neuron (2002) 35:907-920.
    • (2002) Neuron , vol.35 , pp. 907-920
    • Sasaki, Y.1    Cheng, C.2    Uchida, Y.3
  • 8
    • 0028931265 scopus 로고
    • Principles of CDK regulation
    • MORGAN DO: Principles of CDK regulation. Nature (1995) 374:131-134.
    • (1995) Nature , vol.374 , pp. 131-134
    • Morgan, D.O.1
  • 9
    • 0033565616 scopus 로고    scopus 로고
    • Migration defects of CDK5(-/-) neurons in the developing cerebellum is cell autonomous
    • OHSHIMA T, GILMORE EC, LONGENECKER G et al.: Migration defects of CDK5(-/-) neurons in the developing cerebellum is cell autonomous. J. Neurosci. (1999) 19:6017-6026.
    • (1999) J. Neurosci. , vol.19 , pp. 6017-6026
    • Ohshima, T.1    Gilmore, E.C.2    Longenecker, G.3
  • 10
    • 0042490494 scopus 로고    scopus 로고
    • CDK5 is essential for synaptic vesicle endocytosis
    • TAN TC, VALOVA VA, MALLADI CS et al.: CDK5 is essential for synaptic vesicle endocytosis. Nat. Cell Biol. (2003) 5(8):701-10.
    • (2003) Nat. Cell Biol. , vol.5 , Issue.8 , pp. 701-710
    • Tan, T.C.1    Valova, V.A.2    Malladi, C.S.3
  • 11
    • 11144247943 scopus 로고    scopus 로고
    • Cyclin-dependent kinase 5 phosphorylates serine 31 of tyrosine hydroxylase and regulates its stability
    • MOY LY, TSAI LH: Cyclin-dependent kinase 5 phosphorylates serine 31 of tyrosine hydroxylase and regulates its stability. J. Biol. Chem. (2004) 279:54487-5493.
    • (2004) J. Biol. Chem. , vol.279 , pp. 54487-55493
    • Moy, L.Y.1    Tsai, L.H.2
  • 12
    • 5444266880 scopus 로고    scopus 로고
    • Identification of tyrosine hydroxylase as a physiological substrate for CDK5
    • KANSY JW, DAUBNER SC, NISHI A et al.: Identification of tyrosine hydroxylase as a physiological substrate for CDK5. J. Neurochem. (2004) 91:374-84.
    • (2004) J. Neurochem. , vol.91 , pp. 374-384
    • Kansy, J.W.1    Daubner, S.C.2    Nishi, A.3
  • 13
    • 0036469286 scopus 로고    scopus 로고
    • Cyclin-dependent kinase 5 prevents neuronal apoptosis by negative regulation of c-Jun N-terminal kinase 3
    • LI BS, ZHANG L, TAKAHASHI S et al.: Cyclin-dependent kinase 5 prevents neuronal apoptosis by negative regulation of c-Jun N-terminal kinase 3. EMBO J. (2002) 21:324-333.
    • (2002) EMBO J. , vol.21 , pp. 324-333
    • Li, B.S.1    Zhang, L.2    Takahashi, S.3
  • 14
    • 0042817922 scopus 로고    scopus 로고
    • Cyclin-dependent kinase-5 is involved in neuregulin-dependent activation of phosphatidylinositol 3-kinase and Akt activity mediating neuronal survival
    • LI BS, MA W, JAFFE H et al.: Cyclin-dependent kinase-5 is involved in neuregulin-dependent activation of phosphatidylinositol 3-kinase and Akt activity mediating neuronal survival. J. Biol. Chem. (2003) 278(37):35702-35709.
    • (2003) J. Biol. Chem. , vol.278 , Issue.37 , pp. 35702-35709
    • Li, B.S.1    Ma, W.2    Jaffe, H.3
  • 15
    • 1242274335 scopus 로고    scopus 로고
    • Cyclin-dependent kinase 5 regulates dopaminergic and glutamatergic transmission in the striatum
    • CHERGUI K, SVENNINGSSON P, GREENGARD P: Cyclin-dependent kinase 5 regulates dopaminergic and glutamatergic transmission in the striatum. Proc. Natl. Acad. Sci. USA (2004) 101:2191-2196.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 2191-2196
    • Chergui, K.1    Svenningsson, P.2    Greengard, P.3
  • 16
    • 13444265883 scopus 로고    scopus 로고
    • Increased activity of cyclin-dependent kinase 5 leads to attenuation of cocaine-mediated dopamine signaling
    • TAKAHASHI S, OHSHIMA T, CHO A et al.: Increased activity of cyclin-dependent kinase 5 leads to attenuation of cocaine-mediated dopamine signaling. Proc. Natl. Acad. Sci. USA (2005) 102:1737-1742.
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 1737-1742
    • Takahashi, S.1    Ohshima, T.2    Cho, A.3
  • 17
    • 0033540060 scopus 로고    scopus 로고
    • Conversion of p35 to p25 deregulates CDK5 activity and promotes neurodegeneration
    • PATRICK GN, ZUKERBERG L, NIKOLIC M et al.: Conversion of p35 to p25 deregulates CDK5 activity and promotes neurodegeneration. Nature (1999) 402:615-622.
    • (1999) Nature , vol.402 , pp. 615-622
    • Patrick, G.N.1    Zukerberg, L.2    Nikolic, M.3
  • 18
    • 0034682414 scopus 로고    scopus 로고
    • Neurotoxicity induces cleavage of p35 to p25 by calpain
    • LEE M-S, KWON YT, LI M et al.: Neurotoxicity induces cleavage of p35 to p25 by calpain Nature (2000) 405:360-364.
    • (2000) Nature , vol.405 , pp. 360-364
    • Lee, M.-S.1    Kwon, Y.T.2    Li, M.3
  • 19
    • 0037040934 scopus 로고    scopus 로고
    • Calpain-mediated cleavage of the cyclin-dependent kinase-5 activator p39 to p29
    • PATZKE H, TSAI LH: Calpain-mediated cleavage of the cyclin-dependent kinase-5 activator p39 to p29. J. Biol. Chem. (2002) 277:8054-8060.
    • (2002) J. Biol. Chem. , vol.277 , pp. 8054-8060
    • Patzke, H.1    Tsai, L.H.2
  • 20
    • 0035126176 scopus 로고    scopus 로고
    • p35/CDK5 binds and phosphorylates β-catenin and regulates β-catenin/presenilin-1 interaction
    • KESAVAPANY S, LAU KF, MCLOUGHLIN DM et al.: p35/CDK5 binds and phosphorylates β-catenin and regulates β-catenin /presenilin-1 interaction. Eur. J. Neurosci. (2001) 13:241-247.
    • (2001) Eur. J. Neurosci. , vol.13 , pp. 241-247
    • Kesavapany, S.1    Lau, K.F.2    Mcloughlin, D.M.3
  • 21
    • 20444404218 scopus 로고    scopus 로고
    • A specific interaction between muskelin and the cyclin dependent kinase 5 activator p39 promotes peripheral localization of muskelin
    • Mar 28:(Epub ahead of print)
    • LEDEE DR, GAO CY, SETH R et al.: A specific interaction between muskelin and the cyclin dependent kinase 5 activator p39 promotes peripheral localization of muskelin. J. Biol. Chem. (2005) Mar 28:(Epub ahead of print).
    • (2005) J. Biol. Chem.
    • Ledee, D.R.1    Gao, C.Y.2    Seth, R.3
  • 22
    • 0037092515 scopus 로고    scopus 로고
    • CDK5 regulates cell-matrix and cell-cell adhesion in lens epithelial cells
    • NEGASH S, WANG HS, GAO C, LEDEE D, ZELENKA P: CDK5 regulates cell-matrix and cell-cell adhesion in lens epithelial cells. J. Cell Sci. (2002) 115:2109-2117.
    • (2002) J. Cell Sci. , vol.115 , pp. 2109-2117
    • Negash, S.1    Wang, H.S.2    Gao, C.3    Ledee, D.4    Zelenka, P.5
  • 23
    • 0030962126 scopus 로고    scopus 로고
    • The role of cyclin-dependent kinase 5 and a novel regulatory subunit in regulating muscle differentiation and patterning
    • PHILPOTT A, PORRO EB, KIRSCHNER MW, TSAI L-H: The role of cyclin-dependent kinase 5 and a novel regulatory subunit in regulating muscle differentiation and patterning. Genes Dev. (1997) 11:1409-1421.
    • (1997) Genes Dev. , vol.11 , pp. 1409-1421
    • Philpott, A.1    Porro, E.B.2    Kirschner, M.W.3    Tsai, L.-H.4
  • 24
    • 0030983120 scopus 로고    scopus 로고
    • Cyclin-dependent kinase 5, CDK5, is a positive regulator of myogenesis in mouse C2 cells
    • LAZARO J-B, KITZMANN M, POUL M-A et al.: Cyclin-dependent kinase 5, CDK5, is a positive regulator of myogenesis in mouse C2 cells. J. Cell Sci. (1997) 110:1251-1260.
    • (1997) J. Cell Sci. , vol.110 , pp. 1251-1260
    • Lazaro, J.-B.1    Kitzmann, M.2    Poul, M.-A.3
  • 25
    • 2342483179 scopus 로고    scopus 로고
    • Cyclin-dependent kinase 5 phosphorylates signal transducer and activator of transcription 3 and regulates its transcriptional activity
    • FU AK, FU WY, NG AK et al.: Cyclin-dependent kinase 5 phosphorylates signal transducer and activator of transcription 3 and regulates its transcriptional activity. Proc. Natl. Acad. Sci. USA (2004) 101:6728-6733.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 6728-6733
    • Fu, A.K.1    Fu, W.Y.2    Ng, A.K.3
  • 26
    • 0037060410 scopus 로고    scopus 로고
    • Induction of CDK5 activity in rat skeletal muscle after nerve injury
    • FU WY, FU AK, LOK KC, IP FC, IP NY: Induction of CDK5 activity in rat skeletal muscle after nerve injury. Neuroreport (2002) 13:243-247.
    • (2002) Neuroreport , vol.13 , pp. 243-247
    • Fu, W.Y.1    Fu, A.K.2    Lok, K.C.3    Ip, F.C.4    Ip, N.Y.5
  • 27
    • 0035088897 scopus 로고    scopus 로고
    • CDK5 is involved in neuregulin-induced AChR expression at the neuromuscular junction
    • FU AK, FU WY, CHEUNG J et al.: CDK5 is involved in neuregulin-induced AChR expression at the neuromuscular junction. Nat. Neurosci. (2001) 4:374-381.
    • (2001) Nat. Neurosci. , vol.4 , pp. 374-381
    • Fu, A.K.1    Fu, W.Y.2    Cheung, J.3
  • 28
    • 0035823630 scopus 로고    scopus 로고
    • Cyclin-dependent kinase 5 promotes insulin exocytosis
    • LILJA L, YANG SN, WEBB DL et al.: Cyclin-dependent kinase 5 promotes insulin exocytosis. J. Biol. Chem. (2001) 276:34199-34205.
    • (2001) J. Biol. Chem. , vol.276 , pp. 34199-34205
    • Lilja, L.1    Yang, S.N.2    Webb, D.L.3
  • 29
    • 0033864742 scopus 로고    scopus 로고
    • Specific association of increased cyclin-dependent kinase 5 expression with monocytic lineage of differentiation of human leukemia HL60 cells
    • CHEN F, RAO J, STUDZINSKI GP: Specific association of increased cyclin-dependent kinase 5 expression with monocytic lineage of differentiation of human leukemia HL60 cells. J. Leukoc. Biol. (2000) 67:559-566.
    • (2000) J. Leukoc. Biol. , vol.67 , pp. 559-566
    • Chen, F.1    Rao, J.2    Studzinski, G.P.3
  • 30
    • 1642266407 scopus 로고    scopus 로고
    • Cellular senescence requires CDK5 repression of Rac1 activity
    • ALEXANDER K, YANG HS, HINDS PW: Cellular senescence requires CDK5 repression of Rac1 activity. Mol. Cell Biol. (2004) 24:2808-2819.
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 2808-2819
    • Alexander, K.1    Yang, H.S.2    Hinds, P.W.3
  • 31
    • 0036870869 scopus 로고    scopus 로고
    • CDK5 Regulates cell adhesion and migration in corneal epithelial cells
    • GAO C, NEGASH S, GUO HT et al.: CDK5 Regulates cell adhesion and migration in corneal epithelial cells. Mol. Cancer Res. (2002) 1:12-24.
    • (2002) Mol. Cancer Res. , vol.1 , pp. 12-24
    • Gao, C.1    Negash, S.2    Guo, H.T.3
  • 32
    • 4944237715 scopus 로고    scopus 로고
    • CDK5 regulates activation and localization of Src during corneal epithelial wound closure
    • GAO CY, STEPP MA, FARISS R, ZELENKA PS: CDK5 regulates activation and localization of Src during corneal epithelial wound closure. J. Cell Sci. (2004) 117:4089-4098.
    • (2004) J. Cell Sci. , vol.117 , pp. 4089-4098
    • Gao, C.Y.1    Stepp, M.A.2    Fariss, R.3    Zelenka, P.S.4
  • 33
    • 0037370196 scopus 로고    scopus 로고
    • Cell-matrix and cell-cell interactions during corneal epithelial wound healing
    • SUZUKI K, SAITO J, YANAI R et al.: Cell-matrix and cell-cell interactions during corneal epithelial wound healing. Prog. Retin. Eye Res. (2003) 22:113-133.
    • (2003) Prog. Retin. Eye Res. , vol.22 , pp. 113-133
    • Suzuki, K.1    Saito, J.2    Yanai, R.3
  • 34
    • 0037337805 scopus 로고    scopus 로고
    • Direct visualization of a stratified epithelium reveals that wounds heal by unified sliding of cell sheets
    • ZHAO M, SONG B, PU J, FORRESTER JV, MCCAIG CD: Direct visualization of a stratified epithelium reveals that wounds heal by unified sliding of cell sheets. FASEB J. (2003) 17:397-406.
    • (2003) FASEB J. , vol.17 , pp. 397-406
    • Zhao, M.1    Song, B.2    Pu, J.3    Forrester, J.V.4    Mccaig, C.D.5
  • 36
    • 0031797018 scopus 로고    scopus 로고
    • Actin 'purse string' filaments are anchored by E-cadherin-mediated adherens junctions at the leading edge of the epithelial wound, providing coordinated cell movement
    • DANJO Y, GIPSON IK: Actin 'purse string' filaments are anchored by E-cadherin-mediated adherens junctions at the leading edge of the epithelial wound, providing coordinated cell movement. J. Cell Sci. (1998) 111:3323-3332.
    • (1998) J. Cell Sci. , vol.111 , pp. 3323-3332
    • Danjo, Y.1    Gipson, I.K.2
  • 37
    • 0037069690 scopus 로고    scopus 로고
    • Rho GTPases in cell biology
    • ETIENNE-MANNEVILLE S, HALL A: Rho GTPases in cell biology. Nature (2002) 420:629-635.
    • (2002) Nature , vol.420 , pp. 629-635
    • Etienne-Manneville, S.1    Hall, A.2
  • 38
  • 39
    • 0027355597 scopus 로고
    • Corneal and ocular surface histochemistry
    • HAZLETT L: Corneal and ocular surface histochemistry. Prog. Histochem. Cytochem. (1993) 25:1-60.
    • (1993) Prog. Histochem. Cytochem. , vol.25 , pp. 1-60
    • Hazlett, L.1
  • 40
    • 0033991556 scopus 로고    scopus 로고
    • Growth factors: Importance in wound healing and maintenance of transparency of the cornea
    • IMANISHI J, KAMIYAMA K, IGUCHI I et al.: Growth factors: importance in wound healing and maintenance of transparency of the cornea. Prog. Retin. Eye Res. (2000) 19:113-129.
    • (2000) Prog. Retin. Eye Res. , vol.19 , pp. 113-129
    • Imanishi, J.1    Kamiyama, K.2    Iguchi, I.3
  • 41
    • 16244420115 scopus 로고    scopus 로고
    • Sensitizing effect of substance P on corneal epithelial migration induced by IGF-1, fibronectin, or interleukin-6
    • YAMADA N, YANAI R, INUI M, NISHIDA T: Sensitizing effect of substance P on corneal epithelial migration induced by IGF-1, fibronectin, or interleukin-6. Invest. Ophthalmol. Vis. Sci. (2005) 46:833-839.
    • (2005) Invest. Ophthalmol. Vis. Sci. , vol.46 , pp. 833-839
    • Yamada, N.1    Yanai, R.2    Inui, M.3    Nishida, T.4
  • 42
    • 0038685911 scopus 로고    scopus 로고
    • CDK inhibitors in clinical development for the treatment of cancer
    • FISCHER P, GIANELLA-BORRADORI A: CDK inhibitors in clinical development for the treatment of cancer. Expert Opin. Investig. Drugs. (2003) 12:955-970.
    • (2003) Expert Opin. Investig. Drugs , vol.12 , pp. 955-970
    • Fischer, P.1    Gianella-Borradori, A.2
  • 43
    • 0038446704 scopus 로고    scopus 로고
    • Cyclin-dependent protein kinases as therapeutic targets in cardiovascular disease
    • EDO M, ROLDAN M, ANDRES V: cyclin-dependent protein kinases as therapeutic targets in cardiovascular disease. Expert Opin. Ther. Patents (2003) 13:579-588.
    • (2003) Expert Opin. Ther. Patents , vol.13 , pp. 579-588
    • Edo, M.1    Roldan, M.2    Andres, V.3
  • 44
    • 1842588303 scopus 로고    scopus 로고
    • Discovery and development of GSK3 inhibitors for the treatment of Type 2 diabetes
    • WAGMAN AS, JOHNSON KW, BUSSIERE DE: Discovery and development of GSK3 inhibitors for the treatment of Type 2 diabetes. Curr. Pharm. Des. (2004) 10:1105-1137.
    • (2004) Curr. Pharm. Des. , vol.10 , pp. 1105-1137
    • Wagman, A.S.1    Johnson, K.W.2    Bussiere, D.E.3
  • 45
    • 13444253813 scopus 로고    scopus 로고
    • Mechanism of CDK5/p25 Binding by CDK Inhibitors
    • MAPELLI M, MASSIMILIANO L, CROVACE C et al.: Mechanism of CDK5/p25 Binding by CDK Inhibitors. J. Med. Chem. (2005) 48:671-679.
    • (2005) J. Med. Chem. , vol.48 , pp. 671-679
    • Mapelli, M.1    Massimiliano, L.2    Crovace, C.3
  • 46
    • 13244264765 scopus 로고    scopus 로고
    • A CDK5 inhibitory peptide reduces tau hyperphosphorylation and apoptosis in neurons
    • ZHENG YL, KESAVAPANY S, GRAVELL M et al.: A CDK5 inhibitory peptide reduces tau hyperphosphorylation and apoptosis in neurons. EMBO J. (2005) 24:209-20.
    • (2005) EMBO J. , vol.24 , pp. 209-220
    • Zheng, Y.L.1    Kesavapany, S.2    Gravell, M.3
  • 47
    • 0347089037 scopus 로고    scopus 로고
    • Electroporation and RNA interference in the rodent retina in vivo and in vitro
    • MATSUDA T, CEPKO CL: Electroporation and RNA interference in the rodent retina in vivo and in vitro. Proc. Natl. Acad. Sci. USA (2004) 101:16-22.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 16-22
    • Matsuda, T.1    Cepko, C.L.2
  • 48
    • 13844256697 scopus 로고    scopus 로고
    • Transmembrane delivery of protein and peptide drugs by TAT-mediated transduction in the treatment of cancer
    • WADIA JS, DOWDY SF: Transmembrane delivery of protein and peptide drugs by TAT-mediated transduction in the treatment of cancer. Adv. Drug Deliv. Rev. (2005) 57:579-596.
    • (2005) Adv. Drug Deliv. Rev. , vol.57 , pp. 579-596
    • Wadia, J.S.1    Dowdy, S.F.2
  • 49
    • 0026684837 scopus 로고
    • Epidermal growth factor and corneal wound healing. A multicenter study
    • PASTOR JC, CALONGE M: Epidermal growth factor and corneal wound healing. A multicenter study. Cornea (1992) 11:311-314.
    • (1992) Cornea , vol.11 , pp. 311-314
    • Pastor, J.C.1    Calonge, M.2
  • 50
    • 0028921726 scopus 로고
    • Topical fibronectin ophthalmic solution in the treatment of persistent defects of the corneal epithelium
    • Chiron Vision Fibronectin Study Group
    • GORDON JF, JOHNSON P, MUSCH DC: Topical fibronectin ophthalmic solution in the treatment of persistent defects of the corneal epithelium. Chiron Vision Fibronectin Study Group. Am. J. Ophthalmol. (1995) 119:281-287.
    • (1995) Am. J. Ophthalmol. , vol.119 , pp. 281-287
    • Gordon, J.F.1    Johnson, P.2    Musch, D.C.3
  • 51
    • 0032714635 scopus 로고    scopus 로고
    • Ocular surface management in corneal transplantation, a review
    • TSUBOTA K: Ocular surface management in corneal transplantation, a review. Jpn. J. Ophthalmol. (1999) 43:502-508.
    • (1999) Jpn. J. Ophthalmol. , vol.43 , pp. 502-508
    • Tsubota, K.1
  • 52
    • 0344011624 scopus 로고    scopus 로고
    • Evaluation of umbilical cord serum therapy for persistent corneal epithelial defects
    • VAJPAYEE RB, MUKERJI N, TANDON R et al.: Evaluation of umbilical cord serum therapy for persistent corneal epithelial defects. Br. J. Ophthalmol. (2003) 87:1312-1316.
    • (2003) Br. J. Ophthalmol. , vol.87 , pp. 1312-1316
    • Vajpayee, R.B.1    Mukerji, N.2    Tandon3
  • 53
    • 0033873752 scopus 로고    scopus 로고
    • Amniotic membrane transplantation for severe neurotrophic corneal ulcers
    • CHEN HJ, PIRES RT, TSENG SC: Amniotic membrane transplantation for severe neurotrophic corneal ulcers. Br. J. Ophthalmol. (2000) 84:826-833.
    • (2000) Br. J. Ophthalmol. , vol.84 , pp. 826-833
    • Chen, H.J.1    Pires, R.T.2    Tseng, S.C.3
  • 54
  • 55
    • 11144224062 scopus 로고    scopus 로고
    • Trends in contact lens-related corneal ulcers
    • MAH-SADORRA JH, YAVUZ SG, NAJJAR DM et al.: Trends in contact lens-related corneal ulcers. Cornea (2005) 24:51-58.
    • (2005) Cornea , vol.24 , pp. 51-58
    • Mah-Sadorra, J.H.1    Yavuz, S.G.2    Najjar, D.M.3
  • 56
    • 0033954728 scopus 로고    scopus 로고
    • The diagnosis and management of acanthamodeba keratitits
    • MCCULLEY J, ALIZADEH H: The diagnosis and management of acanthamodeba keratitits. CLAO J. (2000) 26:47-51.
    • (2000) CLAO J. , vol.26 , pp. 47-51
    • Mcculley, J.1    Alizadeh, H.2
  • 57
    • 0033506113 scopus 로고    scopus 로고
    • The impact of the herpetic eye disease studies on the management of herpes simplex vius ocular infections
    • SUDESH S, LAIBSON PR: The impact of the herpetic eye disease studies on the management of herpes simplex vius ocular infections. Curr. Opin. Ophthalmol. (1999) 10:230-233.
    • (1999) Curr. Opin. Ophthalmol. , vol.10 , pp. 230-233
    • Sudesh, S.1    Laibson, P.R.2
  • 58
    • 0033758798 scopus 로고    scopus 로고
    • Recurrent erosions of the cornea: Epidemiology and treatment
    • REIDY JJ, PAULUS MP, GONA S: Recurrent erosions of the cornea: epidemiology and treatment. Cornea (2000) 19:767-771.
    • (2000) Cornea , vol.19 , pp. 767-771
    • Reidy, J.J.1    Paulus, M.P.2    Gona, S.3
  • 59
    • 0014382855 scopus 로고
    • Meesman's corneal dystrophy
    • BURNS R: Meesman's corneal dystrophy. Trans. Am. Ophthalmol. Soc. (1968) 66:530-635.
    • (1968) Trans. Am. Ophthalmol. Soc. , vol.66 , pp. 530-635
    • Burns, R.1
  • 60
    • 0031955562 scopus 로고    scopus 로고
    • Natural history of recurrent erosion syndrome - A 4 year review of 117 patients
    • HEYWORTH P, MORLET N, RAYNER S, HYKIN P, DART J: Natural history of recurrent erosion syndrome - a 4 year review of 117 patients. Br. J. Ophthalmol. (1998) 82:26-28.
    • (1998) Br. J. Ophthalmol. , vol.82 , pp. 26-28
    • Heyworth, P.1    Morlet, N.2    Rayner, S.3    Hykin, P.4    Dart, J.5
  • 61
    • 0016664002 scopus 로고
    • The anesthetic eye: An investigation of changes in the anterior ocular segment of the monkey caused by interrupting the trigeminal nerve at various levels along its course
    • ALPER MG: The anesthetic eye: an investigation of changes in the anterior ocular segment of the monkey caused by interrupting the trigeminal nerve at various levels along its course. Trans. Am. Ophthalmol. Soc. (1975) 73:313-365.
    • (1975) Trans. Am. Ophthalmol. Soc. , vol.73 , pp. 313-365
    • Alper, M.G.1
  • 64
    • 0024419193 scopus 로고
    • Decreased penetration of anchoring fibrils into the diabetic stroma. A morphometric analysis
    • AZAR DT, SPURR-MICHAUD SJ, TISDALE AS, GIPSON IK: Decreased penetration of anchoring fibrils into the diabetic stroma. A morphometric analysis. Arch. Ophthalmol. (1989) 107:1520-1523.
    • (1989) Arch. Ophthalmol. , vol.107 , pp. 1520-1523
    • Azar, D.T.1    Spurr-Michaud, S.J.2    Tisdale, A.S.3    Gipson, I.K.4
  • 65
    • 0037226340 scopus 로고    scopus 로고
    • Correlation of corneal sensation, but not of basal or reflex tear secretion, with the stage of diabetic retinopathy
    • SAITO J, ENOKI M, HARA M et al.: Correlation of corneal sensation, but not of basal or reflex tear secretion, with the stage of diabetic retinopathy. Cornea (2003) 22:15-18.
    • (2003) Cornea , vol.22 , pp. 15-18
    • Saito, J.1    Enoki, M.2    Hara, M.3
  • 66
    • 10344241959 scopus 로고    scopus 로고
    • Ocular surface stem cells and disease: Current concepts and clinical applications
    • ANG L, TAN D: Ocular surface stem cells and disease: current concepts and clinical applications. Ann. Acad. Med. Singapore (2004) 33:576-580.
    • (2004) Ann. Acad. Med. Singapore , vol.33 , pp. 576-580
    • Ang, L.1    Tan, D.2
  • 68
    • 0036924593 scopus 로고    scopus 로고
    • Cyclin-dependent kinases as cellular targets for antiviral drugs
    • SCHANG L: Cyclin-dependent kinases as cellular targets for antiviral drugs. J. Antimicrob. Chemother. (2002) 50:779-792.
    • (2002) J. Antimicrob. Chemother. , vol.50 , pp. 779-792
    • Schang, L.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.