Actin 'purse string' filaments are anchored by E-cadherin-mediated adherens junctions at the leading edge of the epithelial wound, providing coordinated cell movement

Journal of Cell Science

Volumn 111, Issue 22, 1998, Pages 3323-3332

  Danjo, Yukitaka ^a   Gipson, Ilene K ^a  

^a SCHEPENS EYE RESEARCH INSTITUTE   (United States)

Author keywords

Actin cytoskeleton; Cell adhesion molecule; Cell movement; Corneal epithelium; Wound healing

Indexed keywords

ACTIN; CATENIN; UVOMORULIN;

ACTIN FILAMENT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL JUNCTION; CELL MOTION; CORNEA INJURY; LAMELLIPODIUM; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; WOUND HEALING;

ACTINS; ANIMALS; ANTIBODIES; BETA CATENIN; BINDING, COMPETITIVE; CADHERINS; CELL MOVEMENT; CORNEA; CYTOSKELETAL PROTEINS; CYTOSKELETON; EPITHELIAL CELLS; INTERCELLULAR JUNCTIONS; MALE; MEMBRANE PROTEINS; MICE; MICE, INBRED BALB C; MYOSINS; PSEUDOPODIA; TRANS-ACTIVATORS; WOUND HEALING;

ANIMALIA;

EID: 0031797018     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (54)

1. Adams, C. L., Nelson, W. J. and Smith, S. J. (1996). Quantitative analysis of cadherin-catenin-actin reorganization during development of cell-cell adhesion. J. Cell Biol. 135, 1899-1911.
2. Angres, B., Barth, A. and Nelson, W. J. (1996). Mechanism for transition from initial to stable cell-cell adhesion: kinetic analysis of E-cadherin-mediated adhesion using a quantitative adhesion assay. J. Cell Biol. 134, 549-557.
3. Bement, W. M., Forscher, P. and Mooseker, M. S. (1993). A novel cytoskeletal structure involved in purse string wound closure and cell polarity maintenance. J. Cell Biol. 121, 565-578.
4. Braga, V. M., Machesky, L. M., Hall, A. and Hotchin, N. A. (1997). The small GTPases Rho and Rac are required for the establishment of cadherin-dependent cell-cell contacts. J. Cell Biol. 137, 1421-1431.
5. Brock, J., Midwinter, K., Lewis, J. and Martin, P. (1996). Healing of incisional wounds in the embryonic chick wing bud: characterization of the actin purse-string and demonstration of a requirement for Rho activation. J. Cell Biol. 135, 1097-1107.
6. Buck, R. C. (1979). Cell migration in repair of mouse corneal epithelium. Invest. Ophthalmol. Vis. Sci. 18, 767-784.
7. Burridge, K., Fath, K., Kelly, T., Nuckolls, G. and Turner, C. (1988). Focal adhesions: Transmembrane junctions between the extracellular matrix and cytoskeleton. Annu. Rev. Cell Biol. 4, 487-525.
8. Condeelis, J. (1993). Life at the leading edge: the formation of cell protrusions. Annu. Rev. Cell Biol. 9, 411-444.
9. Conrad, P. A., Nederlof, M. A., Herman, I. M. and Taylor, D. L. (1989). Correlated distribution of actin, myosin, and microtubules at the leading edge of migrating Swiss 3T3 fibroblasts. Cell Motil. Cytoskel. 14, 527-543.
10. Cowin, P., Kapprell, H. P., Franke, W. W., Tamkun, J. and Hynes R. O. (1986). Plakoglobin: a protein common to different kinds of intercellular adhering junctions. Cell 46, 1063-1073.
11. Cramer, L. P., Mitchison, T. J. and Theriot, J. A. (1994). Actin-dependent motile forces and cell motility. Curr. Opin. Cell Biol. 6, 82-86.
12. Fey, E. G., Wan, K. M. and Penman, S. (1984). Epithelial cytoskeletal framework and nuclear matrix-intermediate filament scaffold: three-dimensional organization and protein composition. J. Cell Biol. 98, 1973-1984.
13. Geiger, B. and Ginsberg, D. (1991). The cytoplasmic domain of adherens-type junctions. Cell. Motil. Cytoskel. 20, 1-6.
14. Geiger, B. and Ayalon, O. (1992). Cadherins. Annu. Rev. Cell. Biol. 8, 307-332.
15. Gipson, I. K. and Anderson, R. A. (1977). Actin filaments in normal and migrating corneal epithelial cells. Invest. Ophthalmol. Vis. Sci. 16, 161-166.
16. Gipson, I. K. and Keezer, L. (1982). Effects of cytochalasins and colchicine on the ultrastructure of migrating corneal epithelium. Invest. Ophthalmol. Vis. Sci. 22, 643-650.
17. Gipson, I. K. and Kiorpes, T. C. (1982). Epithelial sheet movement: protein and glycoprotein synthesis. Dev. Biol. 92, 259-262.
18. Gipson, I. K., Westcott, M. J. and Brooksby, N. G. (1982). Effects of cytochalasins B and D and colchicine on migration of the corneal epithelium. Invest. Ophthalmol. Vis. Sci. 22, 633-642.
19. Gipson, I. K. and Sugrue, S. P. (1994). Cell biology of the corneal epithelium. In Principles and Practice of Ophthalmology (ed. D. M. Albert and F. A. Jakobiec), pp. 3-16. Lippincott, Philadelphia.
20. Hatta, K., Okada, T. S. and Takeichi, M. (1985). A monoclonal antibody disrupting calcium-dependent cell-cell adhesion of brain tissues: possible role of its target antigen in animal pattern formation. Proc. Nat. Acad. Sci. USA 82, 2789-2793.
21. Hirai, Y., Nose, A., Kobayashi, S. and Takeichi, M. (1989a). Expression and role of E- and P-cadherin adhesion molecules in embryonic histogenesis. I. Lung epithelial morphogenesis. Development 105, 263-270.
22. Hirai, Y., Nose, A., Kobayashi, S. and Takeichi, M. (1989b). Expression and role of E- and P-cadherin adhesion molecules in embryonic histogenesis. II. Skin morphogenesis. Development 105, 271-277.
23. Itoh, M., Nagafuchi, A., Yonemura, S., Kitani-Yasuda, T., Tsukita, S. and Tsukita, S. (1993). The 220-kD protein colocalizing with cadherin in non-epithelial cells is identical to ZO-1, a tight junction-associated protein in epithelial cells: cDNA cloning and immunoelectron microscopy. J. Cell Biol. 121, 491-502.
24. Itoh, M., Nagafuchi, A., Moroi, S. and Tsukita, S. (1997). Involvement of ZO-1 in cadherin-based cell adhesion through its direct binding to α-catenin and actin filaments. J. Cell Biol. 138, 181-192.
25. Jockusch, B. M., Bubeck, P., Giehl, K., Kroemker, M., Moschner, J., Rothkegel, M., Rudiger, M., Schluter, K., Stanke, G. and Winkler, J. (1995). The molecular architecture of focal adhesions. Annu. Rev. Cell Dev. Biol. 11, 379-416.
26. Kemler, R. (1993). From cadherins to catenins: cytoplasmic protein interactions and regulation of cell adhesion. Trends Genet. 9, 317-321.
27. Kolega, J. (1997). Asymmetry in the distribution of free versus cytoskeletal myosin II in locomoting microcapillary endothelial cells. Exp. Cell Res. 231, 66-82.
28. Lauffenburger, D. A. and Horwitz, A. F. (1996). Cell migration: a physically integrated molecular process. Cell 84, 359-369.
29. Lavker, R. M., Dong, G., Cheng, S. Z., Kudoh, K., Cotsarelis, G. and Sun, T.T. (1991). Relative proliferative rates of limbal and corneal epithelia. Implications of corneal epithelial migration, circadian rhythm, and suprabasally located DNA-synthesizing keratinocytes. Invest. Ophthalmol. Vis. Sci. 32, 1864-1875.
30. Martin, P. and Lewis, J. (1992). Actin cables and epidermal movement in embryonic wound healing. Nature 360, 179-183.
31. McNeill, H., Ozawa, M., Kemler, R. and Nelson, W. J. (1990). Novel function of the cell adhesion molecule uvomorulin as an inducer of cell surface polarity. Cell 62, 309-316.
32. McNeill, H., Ryan, T. A., Smith, S. J. and Nelson, W. J. (1993). Spatial and temporal dissection of immediate and early events following cadherin-mediated epithelial cell adhesion. J. Cell Biol. 120, 1217-1226.
33. Mitchison, T. J. and Cramer, L. P. (1996). Actin-based cell motility and cell locomotion. Cell 84, 371-379.
34. Nagafuchi, A. and Takeichi, M. (1988). Cell binding function of E-cadherin is regulated by the cytoplasmic domain. EMBO J. 7, 3679-3684.
35. Näthke, I. S., Hinck, L., Swedlow, J. R., Papkoff, J. and Nelson, W. J. (1994). Defining interactions and distributions of cadherin and catenin complexes in polarized epithelial cells. J. Cell Biol. 125, 1341-1352.
36. Ogou, S., Yoshida-Noro, C. and Takeichi, M. (1983). Calcium-dependent cell-cell adhesion molecules common to hepatocytes and teratocarcinoma stem cells. J. Cell Biol. 97, 944-948.
37. Overduin, M., Harvey, T. S., Bagby, S., Tong, K. I., Yau, P., Takeichi, M. and Ikura, M. (1995). Solution structure of the epithelial cadherin domain responsible for selective cell adhesion. Science 267, 386-389.
38. Ozawa, M., Baribault, H. and Kemler, R. (1989). The cytoplasmic domain of the cell adhesion molecule uvomorulin associates with three independent proteins structurally related in different species. EMBO. J. 8, 1711-1717.
39. Ozawa, M., Ringwald, M. and Kemler, R. (1990). Uvomorulin-catenin complex formation is regulated by a specific domain in the cytoplasmic region of the cell adhesion molecule. Proc. Nat. Acad. Sci. USA 87, 4246-4250.
40. Rajasekaran, A. K., Hojo, M., Huima, T. and Rodriguez-Boulan, E. (1996). Catenins and Zonula Occludens-1 form a complex during early stages in the assembly of tight junctions. J. Cell Biol. 132, 451-463.
41. Richardson, K. C., Jarett, L. and Finke, E. H. (1960). Embedding in epoxy resins for ultrathin sectioning in electron microscopy. Stain Technol. 35, 313-323.
42. Ridley, A. J. and Hall, A. (1992). The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors. Cell 70, 389-399.
43. Shimoyama, Y., Hirohashi, S., Hirano, S., Noguchi, M., Shimosato, Y., Takeichi, M. and Abe, O. (1989). Cadherin cell-adhesion molecules in human epithelial tissues and carcinomas. Cancer Res. 49, 2128-2133.
44. Small, J. V. (1994). Lamellipodia architecture: actin filament turnover and the lateral flow of actin filaments during motility. Semin. Cell Biol. 5, 157-163.
45. Spurr-Michaud, S. J., Barza, M. and Gipson, I. K. (1988). An organ culture system for study of adherence of pseudomonas aeruginosa to normal and wounded corneas. Invest. Ophthalmol. Vis. Sci. 29, 379-386.
46. Stevenson, B. R., Siliciano, J. D., Mooseker, M. S. and Goodenough, D. A. (1986). Identification of ZO-1: a high molecular weight polypeptide associated with the tight junction (zonula occludens) in a variety of epithelia. J. Cell Biol. 103, 755-766.
47. Stossel, T. P. (1993). On the crawling of animal cells. Science 260, 1086-1094.
48. Svitkina, T. M., Verkhovsky, A. B., McQuade, K. M. and Borisy, G. G. (1997). Analysis of the actin-myosin II system in fish epidermal keratocytes: mechanism of cell body translocation. J. Cell Biol. 139, 397-415.
49. Takaishi, K., Sasaki, T., Kotani, H., Nishioka, H. and Takai, Y. (1997). Regulation of cell-cell adhesion by rac and rho small G proteins in MDCK cells. J. Cell Biol. 139, 1047-1059.
50. Takeichi, M. (1991). Cadherin cell adhesion receptors as a morphogenetic regulator. Science 251, 1451-1455.
51. Tsukita, S., Tsukita, S., Nagafuchi, A. and Yonemura, S. (1992). Molecular linkage between cadherins and actin filaments in cell-cell adherens junctions. Curr. Opin. Cell Biol. 4, 834-839.
52. Yap, A. S., Brieher, W. M. and Gumbiner, B. M. (1997). Molecular and functional analysis of cadherin-based adherens junctions. Annu. Rev. Cell Dev. Biol. 13, 119-146.
53. Yonemura, S., Itoh, M., Nagafuchi, A. and Tsukita, S. (1995). Cell-to-cell adherens junction formation and actin filament organization: similarities and differences between non-polarized fibroblasts and polarized epithelial cells. J. Cell Sci. 108, 127-142.
54. Yoshida-Noro, C., Suzuki, N. and Takeichi, M. (1984). Molecular nature of the calcium-dependent cell-cell adhesion system in mouse teratocarcinoma and embryonic cells studied with a monoclonal antibody. Dev. Biol. 101, 19-27.