메뉴 건너뛰기




Volumn 19, Issue 4, 1998, Pages 351-361

Septo-hippocampal cholinergic and neurotrophin markers in age-induced cognitive decline

Author keywords

Aging; Cognition; Immunoblotting; In situ hybridization histochemistry; Messenger RNA; Spatial learning

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; MESSENGER RNA; NEUROMODULIN; NEUROTROPHIN; NEUROTROPHIN RECEPTOR;

EID: 0031703711     PISSN: 01974580     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0197-4580(98)00072-4     Document Type: Article
Times cited : (64)

References (69)
  • 1
    • 0026024411 scopus 로고
    • Chronic treatment with scopolamine and physostigmine changes nerve growth factor (NGF) receptor density and NGF content in rat brain
    • Alberch, J.; Carman-Krzan, M.; Fabrazzo, M.; Wise, B. C. Chronic treatment with scopolamine and physostigmine changes nerve growth factor (NGF) receptor density and NGF content in rat brain. Brain Res. 542:233-240; 1991.
    • (1991) Brain Res. , vol.542 , pp. 233-240
    • Alberch, J.1    Carman-Krzan, M.2    Fabrazzo, M.3    Wise, B.C.4
  • 2
    • 0029131221 scopus 로고
    • Selective immunotoxic lesions of basal forebrain cholinergic cells: Effects on learning and memory in rats
    • Baxter, M. G.; Bucci, D. J.; Gorman, L. K.; Wiley, R. G.; Gallagher, M. Selective immunotoxic lesions of basal forebrain cholinergic cells: Effects on learning and memory in rats. Behav. Neurosci. 109:714-722; 1995.
    • (1995) Behav. Neurosci. , vol.109 , pp. 714-722
    • Baxter, M.G.1    Bucci, D.J.2    Gorman, L.K.3    Wiley, R.G.4    Gallagher, M.5
  • 4
    • 0029949494 scopus 로고    scopus 로고
    • Intact spatial learning in both young and aged rats following selective removal of hippocampal cholinergic input
    • Baxter, M. G.; Gallagher, M. Intact spatial learning in both young and aged rats following selective removal of hippocampal cholinergic input. Behav. Neurosci. 110:460-467; 1996.
    • (1996) Behav. Neurosci. , vol.110 , pp. 460-467
    • Baxter, M.G.1    Gallagher, M.2
  • 5
    • 0029931413 scopus 로고    scopus 로고
    • Increased beta-amyloid precursor protein mRNA in the rat cerebral cortex and hippocampus after chronic systemic atropine treatment
    • Beach, T. G.; Walker, D. G.; Cynader, M. S.; Hughes, L. H. Increased beta-amyloid precursor protein mRNA in the rat cerebral cortex and hippocampus after chronic systemic atropine treatment. Neurosci. Lett. 210:13-16; 1996.
    • (1996) Neurosci. Lett. , vol.210 , pp. 13-16
    • Beach, T.G.1    Walker, D.G.2    Cynader, M.S.3    Hughes, L.H.4
  • 6
    • 0031027044 scopus 로고    scopus 로고
    • GAP-43 - An intrinsic determinant of neuronal development and plasticity
    • Benowitz, L. I.; Routtenberg, A. GAP-43 - An intrinsic determinant of neuronal development and plasticity. Trends Neurosci. 20:84-91; 1997.
    • (1997) Trends Neurosci. , vol.20 , pp. 84-91
    • Benowitz, L.I.1    Routtenberg, A.2
  • 7
    • 0030599405 scopus 로고    scopus 로고
    • Expression and polarization of VGF in developing hippocampal neurons
    • Benson, D. L.; Salton, S. R. J. Expression and polarization of VGF in developing hippocampal neurons. Dev. Brain Res. 96:219-228; 1996.
    • (1996) Dev. Brain Res. , vol.96 , pp. 219-228
    • Benson, D.L.1    Salton, S.R.J.2
  • 8
    • 0025734299 scopus 로고
    • The role of oxidative abnormalities in the pathophysiology of Alzheimer's disease
    • Blass, J. P.; Gibson, G. E. The role of oxidative abnormalities in the pathophysiology of Alzheimer's disease. Revue Neurolog. 147:513-525; 1991.
    • (1991) Revue Neurolog. , vol.147 , pp. 513-525
    • Blass, J.P.1    Gibson, G.E.2
  • 9
    • 0026602281 scopus 로고
    • Activation of basal forebrain cholinergic neurons differentially regulates brain-derived neurotrophic factor mRNA expression in different projection areas
    • Boatell, L. L.; Lindefors, N.; Ballarin, M.; Ernfors, P.; Mahy, N.; Persson, H. Activation of basal forebrain cholinergic neurons differentially regulates brain-derived neurotrophic factor mRNA expression in different projection areas. Neurosci. Lett. 136:203-208; 1992.
    • (1992) Neurosci. Lett. , vol.136 , pp. 203-208
    • Boatell, L.L.1    Lindefors, N.2    Ballarin, M.3    Ernfors, P.4    Mahy, N.5    Persson, H.6
  • 10
    • 0029059248 scopus 로고
    • Serine 133-phosphorylated CREB induces transcription via a cooperative mechanism that may confer specificity to neurotrophin signals
    • Bonni, A.; Ginty, d. D.; Dudek, H.; and Greenberg, M. E. Serine 133-phosphorylated CREB induces transcription via a cooperative mechanism that may confer specificity to neurotrophin signals. Mol. Cell Neurosci. 6:168, 183; 1995.
    • (1995) Mol. Cell Neurosci. , vol.6 , pp. 168
    • Bonni, A.1    Ginty, D.D.2    Dudek, H.3    Greenberg, M.E.4
  • 12
    • 0028171962 scopus 로고
    • Reduced transport of [125I]nerve growth factor by cholinergic neurons and down-regulated TrkA expression in the medial septum of aged rats
    • Cooper, J. D.; Lindholm, D.; Sofroniew, M. V. Reduced transport of [125I]nerve growth factor by cholinergic neurons and down-regulated TrkA expression in the medial septum of aged rats. Neurosci. 62:625-629; 1994.
    • (1994) Neurosci. , vol.62 , pp. 625-629
    • Cooper, J.D.1    Lindholm, D.2    Sofroniew, M.V.3
  • 13
    • 0029888642 scopus 로고    scopus 로고
    • Nerve growth factor and Ras regulate beta-amyloid precursor protein gene expression in PC12 cells
    • Cosgaya, J. M.; Latasa, M. J.; Pascual, A. Nerve growth factor and Ras regulate beta-amyloid precursor protein gene expression in PC12 cells. J. Neurochem. 67:98-104; 1996.
    • (1996) J. Neurochem. , vol.67 , pp. 98-104
    • Cosgaya, J.M.1    Latasa, M.J.2    Pascual, A.3
  • 14
    • 0025950097 scopus 로고
    • Hippocampal NGF levels are not reduced in the aged Fischer 344 rat
    • Crutcher, K. A.; and Weingartner, J. Hippocampal NGF levels are not reduced in the aged Fischer 344 rat. Neurbiol. Aging 12:449-454; 1991.
    • (1991) Neurbiol. Aging , vol.12 , pp. 449-454
    • Crutcher, K.A.1    Weingartner, J.2
  • 15
    • 0029166330 scopus 로고
    • The muscarinic Ml agonist xanomeline increases soluble amyloid precursor protein release from Chinese hamster ovary-m1 cells
    • Eckols, K.; Bymaster, F. P.; Mitch, C. H.; Shannon, H. E.; Ward, J. S.; DeLapp, N. W. The muscarinic Ml agonist xanomeline increases soluble amyloid precursor protein release from Chinese hamster ovary-m1 cells. Life Sci. 57:1183-1190; 1995.
    • (1995) Life Sci. , vol.57 , pp. 1183-1190
    • Eckols, K.1    Bymaster, F.P.2    Mitch, C.H.3    Shannon, H.E.4    Ward, J.S.5    DeLapp, N.W.6
  • 16
    • 0030248464 scopus 로고    scopus 로고
    • VGF - A neurotrophin-inducible gene expressed in neuroendocrine tissues
    • Ferri, G. L.; Possenti, R. VGF - A neurotrophin-inducible gene expressed in neuroendocrine tissues. Trends Endocrinol. Metab. 7:233-239; 1996.
    • (1996) Trends Endocrinol. Metab. , vol.7 , pp. 233-239
    • Ferri, G.L.1    Possenti, R.2
  • 17
    • 0029360745 scopus 로고
    • Differential expression of p140trk, p75NGFR and growth-associated phosphoprotein-43 genes in nucleus basalis magnocellularis, thalamus and adjacent cortex following neocortical infarction and nerve growth factor treatment
    • Figueiredo, B. C.; Skup, M.; Bedard, A. M.; Tetzlaff, W.; Cuello, A. C. Differential expression of p140trk, p75NGFR and growth-associated phosphoprotein-43 genes in nucleus basalis magnocellularis, thalamus and adjacent cortex following neocortical infarction and nerve growth factor treatment. Neurosci. 68:29-45; 1995.
    • (1995) Neurosci. , vol.68 , pp. 29-45
    • Figueiredo, B.C.1    Skup, M.2    Bedard, A.M.3    Tetzlaff, W.4    Cuello, A.C.5
  • 18
    • 0026567917 scopus 로고
    • Progressive decline in spatial learning and integrity of forebrain cholinergic neurons in rats during aging
    • Fischer, W.; Chen, K. S.; Gage, F. H.; Bjorklund, A. Progressive decline in spatial learning and integrity of forebrain cholinergic neurons in rats during aging. Neurobiol. Aging 13:9-23; 1992.
    • (1992) Neurobiol. Aging , vol.13 , pp. 9-23
    • Fischer, W.1    Chen, K.S.2    Gage, F.H.3    Bjorklund, A.4
  • 19
    • 0027459976 scopus 로고
    • Nerve growth factor-induced neuronal differentiation is accompanied by differential induction and localization of the amyloid precursor protein (APP) in PC12 cells and variant PC12S cells
    • Fukuyama, R.; Chandrasekaran, K.; Rapoport, S. I. Nerve growth factor-induced neuronal differentiation is accompanied by differential induction and localization of the amyloid precursor protein (APP) in PC12 cells and variant PC12S cells. Mol. Brain Res. 17:17-22; 1993.
    • (1993) Mol. Brain Res. , vol.17 , pp. 17-22
    • Fukuyama, R.1    Chandrasekaran, K.2    Rapoport, S.I.3
  • 20
    • 0025917576 scopus 로고
    • Kainic acid-induced seizures stimulate increased expression of nerve growth factor mRNA in rat hippocampus
    • Gall, C.; Murray, K.; Isackson, P. J. Kainic acid-induced seizures stimulate increased expression of nerve growth factor mRNA in rat hippocampus. Mol. Brain Res. 9:113-123; 1991.
    • (1991) Mol. Brain Res. , vol.9 , pp. 113-123
    • Gall, C.1    Murray, K.2    Isackson, P.J.3
  • 21
    • 0024798104 scopus 로고
    • Relationship of age-related decline across several behavioral domains
    • Gallagher, M.; Burwell, R. Relationship of age-related decline across several behavioral domains. Neurobiol. Aging 10:691-708; 1989.
    • (1989) Neurobiol. Aging , vol.10 , pp. 691-708
    • Gallagher, M.1    Burwell, R.2
  • 22
    • 0027214025 scopus 로고
    • Severity of spatial learning impairment in aging: Development of a learning index for performance in the Morris water maze
    • Gallagher, M.; Burwell, R.; Burchinal, M. Severity of spatial learning impairment in aging: Development of a learning index for performance in the Morris water maze. Behav. Neurosci. 107:618-626; 1993.
    • (1993) Behav. Neurosci. , vol.107 , pp. 618-626
    • Gallagher, M.1    Burwell, R.2    Burchinal, M.3
  • 24
    • 0030639472 scopus 로고    scopus 로고
    • The use of animal models to study the effects of aging on cognition
    • 1997
    • Gallagher, M.; Rapp, P. The use of animal models to study the effects of aging on cognition. Ann. R. Psychol. 48:339-370; 1997, 1997.
    • (1997) Ann. R. Psychol. , vol.48 , pp. 339-370
    • Gallagher, M.1    Rapp, P.2
  • 25
    • 0029983531 scopus 로고    scopus 로고
    • The effect of cholinesterase inhibitors on the secretion of APPS from rat brain cortex
    • Giacobini, E.; Mori, F.; Lai, C. C. The effect of cholinesterase inhibitors on the secretion of APPS from rat brain cortex. Ann. N. Y. Acad. Sci. 777:393-398; 1996.
    • (1996) Ann. N. Y. Acad. Sci. , vol.777 , pp. 393-398
    • Giacobini, E.1    Mori, F.2    Lai, C.C.3
  • 26
    • 0024394332 scopus 로고
    • Function of neurotrophic factors in the adult and aging brain and their possible use in the treatment of neurodegenerative diseases
    • Hefti, F.; Hartikka, J.; Knusel, B. Function of neurotrophic factors in the adult and aging brain and their possible use in the treatment of neurodegenerative diseases. Neurobiol. Aging 10:515-533; 1989.
    • (1989) Neurobiol. Aging , vol.10 , pp. 515-533
    • Hefti, F.1    Hartikka, J.2    Knusel, B.3
  • 27
    • 0022549757 scopus 로고
    • Nerve growth factor and Alzheimer's disease
    • Hefti, F.; Weiner, W. J. Nerve growth factor and Alzheimer's disease. Ann. Neurol. 20:275-281; 1986.
    • (1986) Ann. Neurol. , vol.20 , pp. 275-281
    • Hefti, F.1    Weiner, W.J.2
  • 28
    • 0025641211 scopus 로고
    • Nerve growth factor levels and choline acetyltransferase activity in the brain of aged rats with spatial memory impairments
    • Hellweg, R.; Fischer, W.; Hock, C.; Gage, F. H.; Bjorklund, A.; Thoenen, H. Nerve growth factor levels and choline acetyltransferase activity in the brain of aged rats with spatial memory impairments. Brain Res. 537:123-130; 1990.
    • (1990) Brain Res. , vol.537 , pp. 123-130
    • Hellweg, R.1    Fischer, W.2    Hock, C.3    Gage, F.H.4    Bjorklund, A.5    Thoenen, H.6
  • 29
    • 0026516257 scopus 로고
    • Hippocampal nerve growth factor levels are related to spatial learning ability in aged rats
    • Henriksson, B. G.; Soderstrom, S.; Gower, A. J.; Ebendal, T.; Winblad, B. Hippocampal nerve growth factor levels are related to spatial learning ability in aged rats. Behav. Brain Res. 48:15-20; 1992.
    • (1992) Behav. Brain Res. , vol.48 , pp. 15-20
    • Henriksson, B.G.1    Soderstrom, S.2    Gower, A.J.3    Ebendal, T.4    Winblad, B.5
  • 30
    • 0024709111 scopus 로고
    • NGF induction of NGF receptor gene expression and cholinergic neuronal hypertrophy within the basal forebrain of the adult rat
    • Higgins, G. A.; Koh, S.; Chen, K. S.; Gage, F. H. NGF induction of NGF receptor gene expression and cholinergic neuronal hypertrophy within the basal forebrain of the adult rat. Neuron 3:247-256; 1989.
    • (1989) Neuron , vol.3 , pp. 247-256
    • Higgins, G.A.1    Koh, S.2    Chen, K.S.3    Gage, F.H.4
  • 31
    • 0025252335 scopus 로고
    • Altered levels of amyloid protein precursor transcripts in the basal forebrain of behaviorally impaired aged rats
    • Higgins, G. A.; Oyler, G. A.; Neve, R. L.; Chen, K. S.; Gage, F. H. Altered levels of amyloid protein precursor transcripts in the basal forebrain of behaviorally impaired aged rats. Proc. Natl. Acad. Sci. USA 87:3032-3036; 1990.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 3032-3036
    • Higgins, G.A.1    Oyler, G.A.2    Neve, R.L.3    Chen, K.S.4    Gage, F.H.5
  • 32
    • 0019795577 scopus 로고
    • Age and neurochemical correlates of radial maze performance in rats
    • Ingram, D. K.; London, E. D.; Goodrick, C. L. Age and neurochemical correlates of radial maze performance in rats. Neurobiol. Aging 2:41-47; 1981.
    • (1981) Neurobiol. Aging , vol.2 , pp. 41-47
    • Ingram, D.K.1    London, E.D.2    Goodrick, C.L.3
  • 33
    • 0029114162 scopus 로고
    • Promoter activity of the gene encoding the beta-amyloid precursor protein is up-regulated by growth factors, phorbol ester, retinoic acid and interleukin-1 (IL-1)
    • Lahiri, D. K.; Nail, C. Promoter activity of the gene encoding the beta-amyloid precursor protein is up-regulated by growth factors, phorbol ester, retinoic acid and interleukin-1 (IL-1). Mol. Brain Res. 32:233-240; 1995.
    • (1995) Mol. Brain Res. , vol.32 , pp. 233-240
    • Lahiri, D.K.1    Nail, C.2
  • 34
    • 0027500640 scopus 로고
    • Cholinergic regulation of hippocampal brain-derived neurotrophic factor mRNA expression: Evidence from lesion and chronic cholinergic drug treatment studies
    • Lapchak, P. A.; Araujo, D. M.; Hefti, F. Cholinergic regulation of hippocampal brain-derived neurotrophic factor mRNA expression: Evidence from lesion and chronic cholinergic drug treatment studies. Neurosci. 52:575-585; 1993.
    • (1993) Neurosci. , vol.52 , pp. 575-585
    • Lapchak, P.A.1    Araujo, D.M.2    Hefti, F.3
  • 35
    • 0023574881 scopus 로고
    • Decreased level of nerve growth factor (NGF) and its messenger RNA in the aged rat brain
    • Larkfors, L.; Ebendal, T.; Whittemore, S. R.; Persson, H.; Hoffer, B.; Olson, L. Decreased level of nerve growth factor (NGF) and its messenger RNA in the aged rat brain. Brain Res. 427:55-60; 1987.
    • (1987) Brain Res. , vol.427 , pp. 55-60
    • Larkfors, L.1    Ebendal, T.2    Whittemore, S.R.3    Persson, H.4    Hoffer, B.5    Olson, L.6
  • 36
    • 0028287088 scopus 로고
    • Spatial learning deficits in the aged rats: Neuroanatomical and neurochemical correlates
    • Lee, J. M.; Ross E. R.; Gower, A.; Paris, J. M.; Martensson, R.; and Lorens, S. A. Spatial learning deficits in the aged rats: Neuroanatomical and neurochemical correlates. Brain Res. Bull. 33:489-500; 1994.
    • (1994) Brain Res. Bull. , vol.33 , pp. 489-500
    • Lee, J.M.1    Ross, E.R.2    Gower, A.3    Paris, J.M.4    Martensson, R.5    Lorens, S.A.6
  • 37
    • 0026573196 scopus 로고
    • Septal cholinergic afferents regulate expression of brain-derived neurotrophic factor and beta-nerve growth factor mRNA in rat hippocampus
    • Lindefors, N.; Ernfors, P.; Falkenberg, T.; Persson, H. Septal cholinergic afferents regulate expression of brain-derived neurotrophic factor and beta-nerve growth factor mRNA in rat hippocampus. Exp. Brain Res. 88:78-90; 1992.
    • (1992) Exp. Brain Res. , vol.88 , pp. 78-90
    • Lindefors, N.1    Ernfors, P.2    Falkenberg, T.3    Persson, H.4
  • 38
    • 0028299995 scopus 로고
    • Relationship of APP mRNA transcripts and levels of NGF and low-affinity NGF receptors to behavioral measures of age-related cognitive dysfunction
    • Lindner, M. D.; Dworetzky, S. I.; Sampson, C.; Loy, R. Relationship of APP mRNA transcripts and levels of NGF and low-affinity NGF receptors to behavioral measures of age-related cognitive dysfunction. J. Neurosci. 14:2282-2289; 1994.
    • (1994) J. Neurosci. , vol.14 , pp. 2282-2289
    • Lindner, M.D.1    Dworetzky, S.I.2    Sampson, C.3    Loy, R.4
  • 39
    • 0027524957 scopus 로고
    • The neurotrophic hypothesis and the cholinergic basal forebrain projection
    • Lucidi-Phillipi, C. A.; Gage, F. H. The neurotrophic hypothesis and the cholinergic basal forebrain projection. Prog. Brain Res. 98:241-249; 1993.
    • (1993) Prog. Brain Res. , vol.98 , pp. 241-249
    • Lucidi-Phillipi, C.A.1    Gage, F.H.2
  • 40
    • 0025302857 scopus 로고
    • Spatial memory deficits in aged rats: Contributions of the cholinergic system assessed by ChAT
    • Luine, V.; Hearns, M. Spatial memory deficits in aged rats: Contributions of the cholinergic system assessed by ChAT. Brain Res. 523:321-324; 1990.
    • (1990) Brain Res. , vol.523 , pp. 321-324
    • Luine, V.1    Hearns, M.2
  • 41
    • 0028344036 scopus 로고
    • Differential expression of GAP-43 mRNA in adult central cholinergic neuronal populations
    • McKinney, M.; Kent, C. Differential expression of GAP-43 mRNA in adult central cholinergic neuronal populations. Mol. Brain Res. 23: 213-220; 1994.
    • (1994) Mol. Brain Res. , vol.23 , pp. 213-220
    • McKinney, M.1    Kent, C.2
  • 42
    • 0028918426 scopus 로고
    • Cholinesterase inhibitors increase secretion of APPs in rat brain cortex
    • Mori, F.; Lai, C. C.; Fusi, F.; Giacobini, E. Cholinesterase inhibitors increase secretion of APPs in rat brain cortex. Neuroreport 6:633-636; 1995.
    • (1995) Neuroreport , vol.6 , pp. 633-636
    • Mori, F.1    Lai, C.C.2    Fusi, F.3    Giacobini, E.4
  • 43
    • 0029798860 scopus 로고    scopus 로고
    • Differential regulation of hippocampal neurotrophins during aging in rats
    • Narisawa-saito, M.; Nawa, H. Differential regulation of hippocampal neurotrophins during aging in rats. J. Neurochem. 67:1124-31; 1996.
    • (1996) J. Neurochem. , vol.67 , pp. 1124-1131
    • Narisawa-saito, M.1    Nawa, H.2
  • 45
    • 0026476297 scopus 로고
    • Release of Alzheimer amyloid precursor derivatives stimulated by activation of muscarinic acetylcholine receptors
    • Nitsch, R. M.; Slack, B. E.; Wurtman, R. J.; Growdon, J. H. Release of Alzheimer amyloid precursor derivatives stimulated by activation of muscarinic acetylcholine receptors. Science 258:304-307; 1992.
    • (1992) Science , vol.258 , pp. 304-307
    • Nitsch, R.M.1    Slack, B.E.2    Wurtman, R.J.3    Growdon, J.H.4
  • 46
    • 0028125764 scopus 로고
    • Nerve growth factor content of rat brain increases following basal-forebrain lesions induced by ibotenic acid but not by electrolysis
    • Nitta, A.; Furukawa, Y.; Hayashi, K.; Hasegawa, T.; Nabeshima, T. Nerve growth factor content of rat brain increases following basal-forebrain lesions induced by ibotenic acid but not by electrolysis. Biol. Pharmaceut. Bull. 17:34-38; 1994.
    • (1994) Biol. Pharmaceut. Bull. , vol.17 , pp. 34-38
    • Nitta, A.1    Furukawa, Y.2    Hayashi, K.3    Hasegawa, T.4    Nabeshima, T.5
  • 47
    • 0029869286 scopus 로고    scopus 로고
    • Simplified RT/PCR quantitation of gene transcripts in cultured neuroblastoma (SN49) and microglial (BV-2) cells using capillary electrophoresis and laser-induced fluorescence
    • Personett, D. A.; Chouinard, M.; Sugaya, K.; McKinney, M. Simplified RT/PCR quantitation of gene transcripts in cultured neuroblastoma (SN49) and microglial (BV-2) cells using capillary electrophoresis and laser-induced fluorescence. J. Neurosci. Meth. 65:77-91; 1996.
    • (1996) J. Neurosci. Meth. , vol.65 , pp. 77-91
    • Personett, D.A.1    Chouinard, M.2    Sugaya, K.3    McKinney, M.4
  • 48
    • 0025239154 scopus 로고
    • Distribution of nerve growth factor receptor-like immunoreactivity in the adult rat central nervous system. Effect of colchicine and correlation with the cholinergic system-II. Brainstem, cerebellum and spinal cord
    • Pioro, E. P.; Cuello, A. C. Distribution of nerve growth factor receptor-like immunoreactivity in the adult rat central nervous system. Effect of colchicine and correlation with the cholinergic system-II. Brainstem, cerebellum and spinal cord. Neurosci. 34:89-110; 1990.
    • (1990) Neurosci. , vol.34 , pp. 89-110
    • Pioro, E.P.1    Cuello, A.C.2
  • 49
    • 0025259796 scopus 로고
    • Distribution of nerve growth factor receptor-like immunoreactivity in the adult rat central nervous system. Effect of colchicine and correlation with the cholinergic system-I
    • Pioro, E. P.; Cuello, A. C. Distribution of nerve growth factor receptor-like immunoreactivity in the adult rat central nervous system. Effect of colchicine and correlation with the cholinergic system-I. Forebrain. Neurosci. 34:57-87; 1990.
    • (1990) Forebrain. Neurosci. , vol.34 , pp. 57-87
    • Pioro, E.P.1    Cuello, A.C.2
  • 50
    • 0029821150 scopus 로고    scopus 로고
    • Preserved neuron number in the hippocampus of aged rats with spatial learning deficits
    • Rapp, P. R.; Gallagher, M. Preserved neuron number in the hippocampus of aged rats with spatial learning deficits. Proc. Natl. Acad. Sci. USA 93:9926-9930; 1996.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 9926-9930
    • Rapp, P.R.1    Gallagher, M.2
  • 51
    • 0029055175 scopus 로고
    • Oxidative processes and antioxidative defense mechanisms in the aging brain
    • Reiter, R. J. Oxidative processes and antioxidative defense mechanisms in the aging brain. FASEB J. 9:526-33; 1995.
    • (1995) FASEB J. , vol.9 , pp. 526-533
    • Reiter, R.J.1
  • 52
    • 0026599462 scopus 로고
    • Transcriptional regulation of neuromodulin (GAP-43) in mouse neuroblastoma clone N1E-115 as evaluated by the RT/PCR method
    • Robbins, M.; McKinney, M. Transcriptional regulation of neuromodulin (GAP-43) in mouse neuroblastoma clone N1E-115 as evaluated by the RT/PCR method. Mol. Brain Res. 13:83-92; 1992.
    • (1992) Mol. Brain Res. , vol.13 , pp. 83-92
    • Robbins, M.1    McKinney, M.2
  • 53
    • 0028019154 scopus 로고
    • Role of neurotrophins in cholinergic-neurone function in the adult and aged CNS
    • Rylett, R. J.; Williams, L. R. Role of neurotrophins in cholinergic-neurone function in the adult and aged CNS. Trends Neurosci. 17:486-90; 1994.
    • (1994) Trends Neurosci. , vol.17 , pp. 486-490
    • Rylett, R.J.1    Williams, L.R.2
  • 54
    • 0028927421 scopus 로고
    • Stimulation of vgf gene expression by NGF is mediated through multiple signal transduction pathways involving protein phosphorylation
    • Salton, S. R.; Volonte, C.; D'Arcangelo, G. Stimulation of vgf gene expression by NGF is mediated through multiple signal transduction pathways involving protein phosphorylation. FEBS Lett. 360:106-110; 1995.
    • (1995) FEBS Lett. , vol.360 , pp. 106-110
    • Salton, S.R.1    Volonte, C.2    D'Arcangelo, G.3
  • 56
    • 0028284131 scopus 로고    scopus 로고
    • Increased NGF-like activity in young but not aged rat hippocampus after septal lesions
    • Scott, S. A.; Liang, S.; Weingartner, J. A.; Crutcher, K. A. Increased NGF-like activity in young but not aged rat hippocampus after septal lesions. Neurobiol. Aging 15:337-346.
    • Neurobiol. Aging , vol.15 , pp. 337-346
    • Scott, S.A.1    Liang, S.2    Weingartner, J.A.3    Crutcher, K.A.4
  • 57
    • 0029893741 scopus 로고    scopus 로고
    • Age-related decrease in cholinergic synaptic transmission in three hippocampal subfields
    • Shen, J.; Barnes, C. A. Age-related decrease in cholinergic synaptic transmission in three hippocampal subfields. Neurobiol. Aging 17: 439-51; 1996.
    • (1996) Neurobiol. Aging , vol.17 , pp. 439-451
    • Shen, J.1    Barnes, C.A.2
  • 58
    • 0025906467 scopus 로고
    • Nerve growth fact or-induced neuronal differentiation is accompanied by differential splicing of beta-amyloid precursor mRNAs in the PC12 cell line
    • Smith, C. J.; Wion, D.; Brachet, P. Nerve growth fact or-induced neuronal differentiation is accompanied by differential splicing of beta-amyloid precursor mRNAs in the PC12 cell line. Mol. Brain Res. 10:351-354; 1991.
    • (1991) Mol. Brain Res. , vol.10 , pp. 351-354
    • Smith, C.J.1    Wion, D.2    Brachet, P.3
  • 59
    • 0024203269 scopus 로고
    • Nerve growth factor receptors in the central nervous system
    • Springer, J. E. Nerve growth factor receptors in the central nervous system. Exp. Neurol. 102:354-365; 1988.
    • (1988) Exp. Neurol. , vol.102 , pp. 354-365
    • Springer, J.E.1
  • 60
    • 0029878229 scopus 로고    scopus 로고
    • Molecular indices of neuronal and glial plasticity in the hippocampal formation in a rodent model of age-induced spatial learning impairment
    • Sugaya, K.; Chouinard, M.; Greene, R.; Robbins, M.; Personett, D.; Kent, C.; Gallagher, M.; McKinney, M. Molecular indices of neuronal and glial plasticity in the hippocampal formation in a rodent model of age-induced spatial learning impairment. J. Neurosci. 16:3427-3443; 1996.
    • (1996) J. Neurosci. , vol.16 , pp. 3427-3443
    • Sugaya, K.1    Chouinard, M.2    Greene, R.3    Robbins, M.4    Personett, D.5    Kent, C.6    Gallagher, M.7    McKinney, M.8
  • 61
    • 0029682545 scopus 로고    scopus 로고
    • Do central nervous system neurons require target-derived neurotrophic support for survival throughout adult life and aging?
    • Svendsen, C. N.; Sofroniew, M. V. Do central nervous system neurons require target-derived neurotrophic support for survival throughout adult life and aging? Perspect. Dev. Neurobiol. 3:133-42; 1996.
    • (1996) Perspect. Dev. Neurobiol. , vol.3 , pp. 133-142
    • Svendsen, C.N.1    Sofroniew, M.V.2
  • 62
    • 0030915192 scopus 로고    scopus 로고
    • Brain aging: Changes in the nature of information coding by the hippocampus
    • Tanila, H.; Shapiro, M.; Gallagher, M.; Eichenbaum, H. Brain aging: Changes in the nature of information coding by the hippocampus. J. Neurosci. 17:5155-5166; 1997.
    • (1997) J. Neurosci. , vol.17 , pp. 5155-5166
    • Tanila, H.1    Shapiro, M.2    Gallagher, M.3    Eichenbaum, H.4
  • 65
    • 0026070557 scopus 로고
    • Increased biosynthesis of Alzheimer amyloid precursor protein in the cerebral cortex of rats with lesions of the nucleus basalis of Meynert
    • Wallace, W. C.; Bragin, V.; Robakis, N. K.; Sambamurti, K.; Vander-Putten, D. Increased biosynthesis of Alzheimer amyloid precursor protein in the cerebral cortex of rats with lesions of the nucleus basalis of Meynert. Mol. Brain Res. 10:173-178; 1991.
    • (1991) Mol. Brain Res. , vol.10 , pp. 173-178
    • Wallace, W.C.1    Bragin, V.2    Robakis, N.K.3    Sambamurti, K.4    Vander-Putten, D.5
  • 66
    • 0029013955 scopus 로고
    • Chronic elevation of secreted amyloid precursor protein in subcortically lesioned rats, and its exacerbation in aged rats
    • Wallace, W. C.; Lieberburg, I.; Schenk, D.; Vigo-Pelfrey, C.; Davis, K. L. Chronic elevation of secreted amyloid precursor protein in subcortically lesioned rats, and its exacerbation in aged rats. J. Neurosci. 15:4896-4905; 1995.
    • (1995) J. Neurosci. , vol.15 , pp. 4896-4905
    • Wallace, W.C.1    Lieberburg, I.2    Schenk, D.3    Vigo-Pelfrey, C.4    Davis, K.L.5
  • 67
    • 0023815125 scopus 로고
    • Messenger RNAs of beta-amyloid precursor protein and prion protein are regulated by nerve growth factor in PC12 cells
    • Wion, D.; Le Bert, M.; Brachet, P. Messenger RNAs of beta-amyloid precursor protein and prion protein are regulated by nerve growth factor in PC12 cells. Int. J. Dev. Neurosci. 6:387-393; 1988.
    • (1988) Int. J. Dev. Neurosci. , vol.6 , pp. 387-393
    • Wion, D.1    Le Bert, M.2    Brachet, P.3
  • 68
    • 0028926941 scopus 로고
    • Muscarinic regulation of Alzheimer's disease amyloid precursor prö tein secretion and amyloid beta-protein production in human neuronal NT2N cells
    • Wolf, B. A.; Wertkin, A. M.; Jolly, Y. C.; Yasuda, R. P.; Wolfe, B. B.; Konrad, R. J.; Manning, D.; Ravi, S.; Williamson, J. R.; Lee, V. M. Muscarinic regulation of Alzheimer's disease amyloid precursor prö tein secretion and amyloid beta-protein production in human neuronal NT2N cells. J. Biol. Chem. 270:4916-4922; 1995.
    • (1995) J. Biol. Chem. , vol.270 , pp. 4916-4922
    • Wolf, B.A.1    Wertkin, A.M.2    Jolly, Y.C.3    Yasuda, R.P.4    Wolfe, B.B.5    Konrad, R.J.6    Manning, D.7    Ravi, S.8    Williamson, J.R.9    Lee, V.M.10
  • 69
    • 0029563699 scopus 로고
    • Role of the cholinergic system in the regulation of neurotrophin synthesis
    • Yu, J.; Pizzo, D. P.; Hutton, L. A.; Perez-Polo, J. R. Role of the cholinergic system in the regulation of neurotrophin synthesis. Brain Res. 705:247-252; 1995.
    • (1995) Brain Res. , vol.705 , pp. 247-252
    • Yu, J.1    Pizzo, D.P.2    Hutton, L.A.3    Perez-Polo, J.R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.