Effect of 2-(4-aminophenylmethyl)-6-hydroxy-3, 4-dihydronaphthalen-1 (2H)-one on all-trans and 13-cis-retinoic acid levels in plasma quantified by high performance liquid chromatography coupled to tandem mass spectrometry

Journal of Enzyme Inhibition and Medicinal Chemistry

Volumn 20, Issue 3, 2005, Pages 219-226

  Angotti, Marc ^a   Hartmann, Rolf W ^a   Kirby, Andrew J ^b   Simons, Claire ^b   Nicholls, Paul J ^b   Sewell, Robert D E ^b   Smith, H John ^b  

^a SAARLAND UNIVERSITY   (Germany)

^b CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

High performance liquid chromatography; Liquid liquid extraction; RA; Retinoic acid; Tandem mass spectrometry

Indexed keywords

2 (4 AMINOPHENYLMETHYL) 6 HYDROXY 3,4 DIHYDRONAPHTHALEN 1(2H) ONE; CYTOCHROME P450; CYTOCHROME P450 INHIBITOR; ISOTRETINOIN; KETOCONAZOLE; LIAROZOLE FUMARATE; N [4 [2 ETHYL 1 (1H 1,2,4 TRIAZOL 1 YL)BUTYL]PHENYL] 2 BENZOTHIAZOLAMINE; RETINOIC ACID; TETRALIN DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; DRUG STRUCTURE; ENZYME INHIBITION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; IN VIVO STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SKIN DISEASE; STRUCTURE ANALYSIS; TANDEM MASS SPECTROMETRY; VITAMIN BLOOD LEVEL; VITAMIN METABOLISM;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ISOTRETINOIN; KETOCONAZOLE; MALE; MASS SPECTROMETRY; NAPHTHALENES; RATS; RATS, INBRED WF; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TETRALONES; TRETINOIN;

EID: 22544456912     PISSN: 14756366     EISSN: None     Source Type: Journal    
DOI: 10.1080/14756360400008889     Document Type: Article

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