Inhibition of retinoic acid metabolising enzymes by 2-(4-aminophenylmethyl)-6-hydroxy-3,4-dihydronaphthalen-1(2H)-one and related compounds

Journal of Enzyme Inhibition and Medicinal Chemistry

Volumn 18, Issue 1, 2003, Pages 27-33

  Kirby, Andrew J ^a   Le Lain, Regis ^a   Maharlouie, Farshid ^a   Mason, Peter ^a   Nicholls, Paul J ^a   Smith, H John ^a   Simons, Claire ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

Ketoconazole; RA; RA metabolising enzyme inhibitors; RA metabolism blocking agents; RAMBAs; Retinoic acid

Indexed keywords

2 (4 AMINOPHENYLMETHYL) 6 HYDROXY 3,4 DIHYDRONAPHTHALEN 1(2H) ONE; DRUG METABOLIZING ENZYME; ENZYME INHIBITOR; KETOCONAZOLE; LIAROZOLE FUMARATE; N [4 [2 ETHYL 1 (1H 1,2,4 TRIAZOL 1 YL)BUTYL]PHENYL] 2 BENZOTHIAZOLAMINE; PYRROLIDINE DERIVATIVE; RETINOIC ACID; RETINOL; TRIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CADAVER; CANCER; CONTROLLED STUDY; DRUG POTENCY; DRUG STRUCTURE; ENZYME INHIBITION; ENZYME SYNTHESIS; FIBROBLAST CULTURE; GENITAL SYSTEM; HUMAN; HUMAN CELL; MAMMAL; MICROSOME; NONHUMAN; PRIORITY JOURNAL; RAT; SKIN DISEASE; TISSUE HOMOGENATE;

ANIMALS; ENZYME INHIBITORS; HUMANS; MALE; NAPHTHALENES; RATS; RATS, WISTAR; TRETINOIN;

ANIMALIA; MAMMALIA;

EID: 0037323055     PISSN: 14756366     EISSN: None     Source Type: Journal    
DOI: 10.1080/1475636021000049221     Document Type: Article

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