Deficiency in cardiac dystrophin affects the abundance of the α-/β-dystroglycan complex

Journal of Biomedicine and Biotechnology

Volumn 2005, Issue 1, 2005, Pages 28-36

  Lohan, James ^a   Culligan, Kevin ^a   Ohlendieck, Kay ^a  

^a NATIONAL UNIVERSITY OF IRELAND   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA DYSTROGLYCAN; BETA DYSTROGLYCAN; CALCIUM CHANNEL; CALCIUM ION; DYSTROPHIN; GLYCOPROTEIN; MEMBRANE PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARDIOMYOPATHY; COMPARATIVE STUDY; CONTROLLED STUDY; CROSS LINKING; DUCHENNE MUSCULAR DYSTROPHY; GENE MUTATION; HEART MUSCLE; IMMUNOBLOTTING; MOUSE; MUSCULAR DYSTROPHY; NONHUMAN; PROTEIN DEFICIENCY; SARCOLEMMA; SKELETAL MUSCLE; X CHROMOSOME LINKED DISORDER;

EID: 22544433443     PISSN: 11107243     EISSN: None     Source Type: Journal    
DOI: 10.1155/JBB.2005.28     Document Type: Article

References (43)

1. Ahn AH, Kunkel LM. The structural and functional diversity of dystrophin. Nat Genet. 1993;3(4):283-291.
2. Emery AE. The muscular dystrophies. Lancet. 2002;359(9307):687-695.
3. Biggar WD, Klamut HJ, Demacio PC, Stevens DJ, Ray PN. Duchenne muscular dystrophy: current knowledge, treatment, and future prospects. Clin Orthop. 2002;401:88-106.
4. Muntoni F, Torelli S, Ferlini A. Dystrophin and mutations: one gene, several proteins, multiple phenotypes. Lancet Neurol. 2003;2(12):731-740.
5. Culligan KG, Mackey AJ, Finn DM, Maguire PB, Ohlendieck K. Role of dystrophin isoforms and associated proteins in muscular dystrophy. Int J Mol Med. 1998;2(6):639-648.
6. Cox GF, Kunkel LM. Dystrophies and heart disease. Curr Opin Cardiol. 1997;12(3):329-343.
7. Anderson JL, Head SI, Rae C, Morley JW. Brain function in Duchenne muscular dystrophy. Brain. 2002;125(pt 1):4-13.
8. Muntoni F. Cardiomyopathy in muscular dystrophies. Curr Opin Neurol. 2003;16(5):577-583.
9. Finsterer J, Stollberger C. The heart in human dystrophinopathies. Cardiology. 2003;99(1):1-19.
10. Sunada Y, Campbell KP. Dystrophin-glycoprotein complex: molecular organization and critical roles in skeletal muscle. Curr Opin Neurol. 1995;8(5):379-384.
11. Ohlendieck K. Towards an understanding of the dystrophin-glycoprotein complex: linkage between the extracellular matrix and the membrane cytoskeleton in muscle fibers. Eur J Cell Biol. 1996;69(1):1-10.
12. Henry MD, Campbell KP. Dystroglycan inside and out. Curr Opin Cell Biol. 1999;11(5):602-607.
13. Ibraghimov-Beskrovnaya O, Ervasti JM, Leveille CJ, Slaughter CA, Sernett SW, Campbell KP. Primary structure of dystrophin-associated glycoproteins linking dystrophin to the extracellular matrix. Nature. 1992;355(6362):696-702.
14. Ohlendieck K, Matsumura K, Ionasescu VV, et al. Duchenne muscular dystrophy: deficiency of dystrophin-associated proteins in the sarcolemma. Neurology. 1993;43(4):795-800.
15. Alderton JM, Steinhardt RA. How calcium influx through calcium leak channels is responsible for the elevated levels of calcium-dependent proteolysis in dystrophic myotubes. Trends Cardiovasc Med. 2000;10(6):268-272.
16. Alderton JM, Steinhardt RA. Calcium influx through calcium leak channels is responsible for the elevated levels of calcium-dependent proteolysis in dystrophic myotubes. J Biol Chem. 2000;275(13):9452-9460.
17. Durbeej M, Campbell KP. Muscular dystrophies involving the dystrophin-glycoprotein complex: an overview of current mouse models. Curr Opin Genet Dev. 2002;12(3):349-361.
18. Sicinski P, Geng Y, Ryder-Cook AS, Barnard EA, Darlison MG, Barnard PJ. The molecular basis of muscular dystrophy in the max mouse: a point mutation. Science. 1989;244(4912):1578-1580.
19. Bia BL, Cassidy PJ, Young ME, et al. Decreased myocardial nNOS, increased iNOS and abnormal ECGs in mouse models of Duchenne muscular dystrophy. J Mol Cell Cardiol. 1999;31(10):1857-1862.
20. Bridges LR. The association of cardiac muscle necrosis and inflammation with the degenerative and persistent myopathy of MDX mice. J Neurol Sci. 1986;72(2-3):147-157.
21. Chu V, Otero JM, Lopez O, et al. Electrocardiographic findings in mdx mice: a cardiac phenotype of Duchenne muscular dystrophy. Muscle Nerve. 2002;26(4):513-519.
22. Sapp JL, Bobet J, Howlett SE. Contractile properties of myocardium are altered in dystrophin-deficient mdx mice. J Neurol Sci. 1996;142(1-2):17-24.
23. Lefaucheur JP, Pastoret C, Sebille A. Phenotype of dystrophinopathy in old mdx mice. Anat Rec. 1995;242(1):70-76.
24. Nakamura A, Yoshida K, Takeda S, Dohi N, Ikeda S. Progression of dystrophic features and activation of mitogen-activated protein kinases and calcineurin by physical exercise, in hearts of mdx mice. FEBS Lett. 2002;520(1-3):18-24.
25. Dowling P, Lohan J, Ohlendieck K. Comparative analysis of Dp427-deficient mdx tissues shows that the milder dystrophic phenotype of extraocular and toe muscle fibres is associated with a persistent expression of beta-dystroglycan. Eur J Cell Biol. 2003;82(5):222-230.
26. Murray BE, Ohlendieck K. Cross-linking analysis of the ryanodine receptor and alpha1-dihydropyridine receptor in rabbit skeletal muscle triads. Biochem J. 1997;324(pt 2):689-696.
27. 2+-ATPase SERCA2 in cardiac muscle. Mol Cell Biol Res Commun. 1999;1(3):182-187.
28. Dunn MJ, Bradd SJ. Separation and analysis of membrane proteins by SDS-polyacrylamide gel electrophoresis. Methods Mol Biol. 1993;19:203-210.
29. Towbin H, Staehelin T, Gordon J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci USA. 1979;76(9):4350-4354.
30. Glover L, Quinn S, Ryan M, Pette D, Ohlendieck K. Supramolecular calsequestrin complex. Eur J Biochem. 2002;269(18):4607-4616.
31. Campbell KP. Three muscular dystrophies: loss of cytoskeleton- extracellular matrix linkage. Cell. 1995;80(5):675-679.
32. Cox GA, Phelps SF, Chapman VM, Chamberlain JS. New mdx mutation disrupts expression of muscle and nonmuscle isoforms of dystrophin. Nat Genet. 1993;4(1):87-93.
33. Han KK, Richard C, Delacourte A. Chemical crosslinks of proteins by using bifunctional reagents. Int J Biochem. 1984;16:129-145.
34. Gaffney BJ. Chemical and biochemical crosslinking of membrane components. Biochim Biophys Acta. 1985;822(3-4):289-317.
35. Mattson G, Conklin E, Desai S, Nielander G, Savage MD, Morgensen S. A practical approach to crosslinking. Mol Biol Rep. 1993;17(3):167-183.
36. 2+-regulatory membrane components involved in the excitation-contraction-relaxation cycle during postnatal development of rabbit skeletal muscle. Biochim Biophys Acta. 1998;1387(1-2):226-238.
37. Froemming GR, Murray BE, Ohlendieck K. Self-aggregation of triadin in the sarcoplasmic reticulum of rabbit skeletal muscle. Biochim Biophys Acta. 1999;1418(1):197-205.
38. Froemming GR, Ohlendieck K. Native skeletal muscle dihydropyridine receptor exists as a supramolecular triad complex. Cell Mol Life Sci 2001;58(2):312-320.
39. Hainsey TA, Senapati S, Kuhn DE, Rafael JA. Cardiomyopathic features associated with muscular dystrophy are independent of dystrophin absence in cardiovasculature. Neuromuscul Disord. 2003;13(4):294-302.
40. Yue Y, Li Z, Harper SQ, Davisson RL, Chamberlain JS, Duan D. Microdystrophin gene therapy of cardiomyopathy restores dystrophin-glycoprotein complex and improves sarcolemma integrity in the mdx mouse heart. Circulation. 2003;108(13):1626-1632.
41. Klietsch R, Ervasti JM, Arnold W, Campbell KP, Jorgensen AO. Dystrophin-glycoprotein complex and laminin colocalize to the sarcolemma and transverse tubules of cardiac muscle. Circ Res. 1993;72(2):349-360.
42. Peri V, Ajdukovic B, Holland P, Tuana BS. Dystrophin predominantly localizes to the transverse tubule/Z-line regions of single ventricular myocytes and exhibits distinct associations with the membrane. Mol Cell Biochem. 1994;130(1):57-65.
43. Rohman MS, Emoto N, Takeshima Y, Yokoyama M, Matsuo M. Decreased mAKAP, ryanodine receptor, and SERCA2a gene expression in mdx hearts. Biochem Biophys Res Commun. 2003;310(1):228-235.