An increased receptive field of olfactory receptor Or43a in the antennal lobe of Drosophila reduces benzaldehyde-driven avoidance behavior

Chemical Senses

Volumn 30, Issue 1, 2005, Pages 81-87

  Störtkuhl, Klemens F ^a   Kettler, Raffael ^a   Fischer, Sven ^a   Hovemann, Bernhard T ^a  

^a RUHR UNIVERSITY BOCHUM   (Germany)

Author keywords

Coding; Ligand; Neuron; Olfaction; Smell

Indexed keywords

ACETIC ACID ETHYL ESTER; BENZALDEHYDE; BENZALDEHYDE DERIVATIVE; DROSOPHILA PROTEIN; OR43A PROTEIN, DROSOPHILA;

ANIMAL BEHAVIOR; ANTENNA; ARTICLE; AVOIDANCE BEHAVIOR; DROSOPHILA; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MAZE TEST; NONHUMAN; ODOR; OLFACTORY RECEPTOR; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTIVE FIELD; RISK REDUCTION; SENSORY STIMULATION; SMELLING; WILD TYPE; ANIMAL; GENETICS; GROWTH, DEVELOPMENT AND AGING; HISTOLOGY; METABOLISM; PHYSIOLOGY; SENSE ORGAN;

ANIMALIA;

ANIMALS; AVOIDANCE LEARNING; BENZALDEHYDES; DROSOPHILA; DROSOPHILA PROTEINS; MAZE LEARNING; OLFACTORY RECEPTOR NEURONS; RECEPTORS, ODORANT; SENSE ORGANS; SMELL;

EID: 22344453515     PISSN: 0379864X     EISSN: None     Source Type: Journal    
DOI: 10.1093/chemse/bji003     Document Type: Article

References (43)

1. Acebes, A. and Ferrus, A. (2001) Increasing the number of synapses modifies olfactory perception in Drosophila. J. Neurosci., 21, 6264-6273.
2. Ang, L.H., Kim, J., Stepensky, V. and Hing, H. (2003) Dock and Pak regulate olfactory axon pathfinding in Drosophila. Development, 130, 1307-1316
3. Anholt, R.R., Fanara, J.J., Fedorowicz, G.M., Ganguly, I., Kulkarni, N.H., Mackay, T.F. and Rollmann, S.M. (2001) Functional genomics of odor-guided behavior in Drosophila melanogaster. Chem. Senses, 26, 215-221.
4. Ayyub, C., Paranjape, J., Rodrigues, V. and Siddiqi, O. (1990) Genetics of olfactory behavior in Drosophila melanogaster. J. Neurogenet., 6, 243-262.
5. Brand, A.H. and Perrimon, N. (1993) Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development, 118, 401-415.
6. Christensen, T.A., Waldrop, B.R. and Hildebrand, J.G. (1998) Multitasking in the olfactory system: context-dependent responses to odors reveal dual GABA-regulated coding mechanisms in single olfactory projection neurons. J. Neurosci., 18, 5999-6008.
7. Connolly, J.B., Roberts, I.J., Armstrong, J.D., Kaiser, K., Forte, M., Tully, T. and O'Kane, C.J. (1996) Associative learning disrupted by impaired Gs signaling in Drosophila mushroom bodies. Science, 274, 2104-2107.
8. Devaud, J.M. (2003) Experimental studies of adult Drosophila chemosensory behaviour. Behav. Proc., 64, 177-196.
9. Devaud, J.M., Acebes, A. and Ferrus, A. (2001) Odor exposure causes central adaptation and morphological changes in selected olfactory glomeruli in Drosophila. J. Neurosci., 21, 6274-6282.
10. Dobritsa, A.A., van der Goes van Naters, W., Warr, C.G., Steinbrecht, R.A. and Carlson, J.R. (2003) Integrating the molecular and cellular basis of odor coding in the Drosophila antenna. Neuron, 37, 827-841.
11. Elmore, T. and Smith, D.P. (2001) Putative Drosophila odor receptor OR43b localizes to dendrites of olfactory neurons. Insect. Biochem. Mol. Biol., 31, 791-798.
12. Elmore, T., Ignell, R., Carlson, J.R. and Smith, D.P. (2003) Targeted mutation of a Drosophila odor receptor defines receptor requirement in a novel class of sensillum. J. Neurosci., 23, 9906-9912.
13. Ferveur, J.F., Stortkuhl, K.F., Stocker, R.F. and Greenspan, R.J. (1995) Genetic feminization of brain structures and changed sexual orientation in male Drosophila. Science, 267, 902-905.
14. Fiala, A., Spall, T., Diegelmann, S., Eisermann, B., Sachse, S., Devaud, J.M., Buchner, E. and Galizia, C.G. (2002) Genetically expressed cameleon in Drosophila melanogaster is used to visualize olfactory information in projection neurons. Curr. Biol., 12, 1877-1884.
15. Gao, Q., Yuan, B. and Chess, A. (2000) Convergent projections of Drosophila olfactory neurons to specific glomeruli in the antennal lobe. Nat. Neurosci., 3, 780-785.
16. Hallem, E.A., Ho, M.G. and Carlson, J.R. (2004) The molecular basis of odor coding in the Drosophila antenna. Cell, 117, 965-979.
17. Helfand, S.L. and Carlson, J.R. (1989) Isolation and characterization of an olfactory mutant in Drosophila with a chemically specific defect. Proc. Natl Acad. Sci. USA, 86, 2908-2912.
18. Hummel, T. Zipursky, S.L. (2004) Afferent induction of olfactory glomeruli requires N-cadherin. Neuron, 42, 77-88.
19. Hummel, T., Vasconcelos, M.L., Clemens, J.C., Fishilevich, Y., Vosshall, L.B. and Zipursky, S.L. (2003) Axonal targeting of olfactory receptor neurons in Drosophila is controlled by Dscam. Neuron, 37, 221-231.
20. Jhaveri, D., Sen, A. and Rodrigues, V. (2000) Mechanisms underlying olfactory neuronal connectivity in Drosophila - the atonal lineage organizes the periphery while sensory neurons and glia pattern the olfactory lobe. Dev. Biol., 226, 73-87.
21. Jhaveri, D. and Rodrigues, V. (2002) Sensory neurons of the Atonal lineage pioneer the formation for glomeruli within the adult Drosophila olfactory lobe. Development, 130, 1251-1260.
22. Keller, A., Sweeney, S.T., Zars, T., O'Kane, C.J. and Heisenberg, M. (2002) Targeted expression of tetanus neurotoxin interferes with behavioral responses to sensory input in Drosophila. J. Neurobiol., 50, 221-233.
23. Laissue, P.P., Reiter, C., Hiesinger, P.R., Halter, S., Fischbach, K.F. and Stocker, R.F. (1999) Three-dimensional reconstruction of the antennal lobe in Drosophila melanogaster. J. Comp. Neurol., 405, 543-552.
24. Lilly, M. and Carlson, J. (1990) smellblind: a gene required for Drosophila olfaction. Genetics, 124, 293-302.
25. McKenna, M., Monte, P., Helfand, S.L., Woodard, C. and Carlson, J. (1989) A simple chemosensory response in Drosophila and the isolation of acj mutants in which it is affected. Proc. Natl Acad. Sci. USA, 86, 8118-8122.
26. Ng, M., Roorda, R.D., Lima, S.Q., Zemelman, B.V., Morcillo, P. and Miesenbock, G. (2002) Transmission of olfactory information between three populations of neurons in the antennal lobe of the fly. Neuron, 36, 463-474.
27. O'Dell, K.M., Armstrong, J.D., Yang, M.Y. and Kaiser, K. (1995) Functional dissection of the Drosophila mushroom bodies by selective feminization of genetically defined subcompartments. Neuron, 15, 55-61.
28. Rodrigues, V. and Buchner, E. (1984) [3H]2-deoxyglucose mapping of odor-induced neuronal activity in the antennal lobes of Drosophila melanogaster. Brain Res., 324, 374-378.
29. Sachse, S. and Galizia, C.G. (2002) Role of inhibition for temporal and spatial odor representation in olfactory output neurons: a calcium imaging study. J. Neurophysiol., 87, 1106-1117.
30. Sachse, S. and Galizia, C.G. (2003) The coding of odour-intensity in the honeybee antennal lobe: local computation optimizes odour representation. Eur. J. Neurosci., 18, 2119-2132.
31. Siddiqi, O. (1983) Olfactory neurogenetics in Drosophila. In Chopra, V.L. Joshi, B.C., Sharma, R.C. and Bansal, H.C. (eds), Genetics: New Frontiers (Vol. III). New Dehli, Oxford University Press, pp. 243-261.
32. Siddiqi, O. (1987) Neurogenetics of olfaction in Drosophila melanogaster. Trends Genet., 3, 137-142.
33. Stortkuhl, K.F. and Kettler, R. (2001) Functional analysis of an olfactory receptor in Drosophila melanogaster. Proc. Natl Acad. Sci. USA, 98, 9381-9385.
34. Stortkuhl, K.F., Hovemann, B.T. and Carlson, J.R. (1999) Olfactory adaptation depends on the Trp Ca2+ channel in Drosophila. J. Neurosci., 19, 4839-4846.
35. Tissot, M., Gendre, N., Hawken, A., Stortkuhl, K.F. and Stocker, R.F. (1997) Larval chemosensory projections and invasion of adult afferents in the antennal lobe of Drosophila. J. Neurobiol., 32, 281-297.
36. Tissot, M., Gendre, N. and Stocker, R.F. (1998) Drosophila P[Gal4] lines reveal that motor neurons involved in feeding persist through metamorphosis. J. Neurobiol., 37, 237-250.
37. Troemel, E.R., Kimmel, B.E. and Bargmann, C.I. (1997) Reprogramming chemotaxis responses: sensory neurons define olfactory preferences in C. elegans. Cell, 91, 161-169.
38. Vosshall, L.B., Amrein, H., Morozov, P.S., Rzhetsky, A. and Axel, R. (1999) A spatial map of olfactory receptor expression in the Drosophila antenna. Cell, 96, 725-736.
39. Vosshall, L.B., Wong, A.M. and Axel, R. (2000) An olfactory sensory map in the fly brain. Cell, 102, 147-159.
40. Wang, J.W., Wong, A.M., Flores, J., Vosshall, L.B. and Axel, R. (2003) Two-photon calcium imaging reveals an odor-evoked map of activity in the fly brain. Cell, 112, 271-282.
41. Wilson, R.I., Turner, G.C. and Laurent, G. (2004) Transformation of olfactory representations in the Drosophila antennal lobe. Science, 303, 366-370.
42. Yu, D., Ponomarev, A. and Davis, R.L. (2004) Altered representation of the spatial code for odors after olfactory classical conditioning: memory trace formation by synaptic recruitment. Neuron, 42,437-449.
43. Zars, T., Fischer, M., Schulz, R. and Heisenberg, M. (2000) Localization of a short-term memory in Drosophila. Science, 288, 672-675.